| Patent application number | Description | Published |
|---|
| 20080213753 | METHOD FOR THE VERIFICATION OF THE REMOVAL OF VIRUSES TO VALIDATE FILTERS AND FILTERING PROCESSES - Disclosed is a method for verification of the removal of viruses to validate filters, filtering processes, physical and chemical inactivation processes, or adsorptive removal processes in predefined process conditions that are simulated on a small scale. According to said method, viruses are cultured in suitable cell lines in a first step, a virus suspension is obtained after solubilizing cells in a second step, the virus suspension obtained is added in a third step to a protein solution that is to be analyzed, and the virus-containing protein solution is filtered through the filter that is to be validated, and the removal of viruses is then analyzed in a fourth step. The virus suspension is first processed via a membrane adsorber following step two, the viruses being bonded to the membrane adsorber and contaminants being removed with the aid of a detergent buffer solution, while the bonded, purified viruses are eluted from the membrane adsorber area and are added to the protein solution that is to be analyzed as a concentrated virus suspension in step three. | 09-04-2008 |
| 20090050213 | Connector, Connector System and Use Thereof - The invention relates to a connector ( | 02-26-2009 |
| 20090075362 | Disposable Bioreactor Comprising a Sensor Arrangement - The invention relates to a disposable bioreactor comprising a reversible, externally attachable sensor arrangement for measuring a physical variable of a contained medium. A sensor adapter ( | 03-19-2009 |
| 20090103772 | Method and Detection Device for the Imaging Detection of a Sample - The invention relates to a device for detecting a sample in a longitudinal sample container ( | 04-23-2009 |
| 20090188871 | Device, method and computer program product for carrying out a process for the filtration of fluids - The invention relates to a filtration system and method for carrying out a process for the filtration of fluids, comprising at least one filtration device with at least one filtration element comprising readable data and a check and/or test apparatus to which the filtration device may be connected, by means of data and testing means lines. The check and/or testing device is connected to a process controller, by data exchange means, for regulation and control of the filtration process and the process controller is connected to a filtration databank, by means of data exchange means, which comprises data sets for at least one filter element and/or for each filtration device and/or for the filtration process. The invention further relates to a computer programme product for carrying out a filtration process on fluids whereby programme components may be called up from a programme memory which support the carrying out of the filtration process. | 07-30-2009 |
| 20090263848 | Method for Determining the Viability of Cells in Cell Cultures - The invention relates to a method for determining the viability of cells in cell cultures, said method comprising the steps of: colouring the sample with a dye which can penetrate into individual cells depending on the viability of the latter, determining the proportions of cells which are coloured to differing extents. The invention is distinguished by virtue of the fact that a cell suspension of the coloured cells is centrifuged as a sample in a sample vessel ( | 10-22-2009 |
| 20090275121 | Vibrational Mixer - A vibrational mixer ( | 11-05-2009 |
| 20090311775 | Disposable Bioreactor for Culturing Cells in a Nutrient Medium - Disposable bioreactor for culturing cells in a nutrient medium, consisting of a reagent container which is sealable with a lid and which is capable of being subjected to a shaking process in a shaking device, where the reagent container is equipped with at least one web adjacent to the internal wall of the container, the web being arranged running vertically from the bottom upward, preferably in the shape of a helix. | 12-17-2009 |
| 20090314666 | Container System With One Container With a Flexible Partition - Container system with one container ( | 12-24-2009 |
| 20100072125 | FILTER CARTRIDGE UNIT WITH ADHESIVE INTERCONNECTING FILTER CARTRIDGE AND END PLATES - A filter cartridge unit including a first end plate, at least one second end plate, and a filter cartridge that is arranged between the end plates. The filter cartridge is connected, in a form-fitting and fluid-tight manner, to its adjacent end plates in a circumferential subarea of contact surfaces thereof using an adhesive. | 03-25-2010 |
| 20100170400 | Waste gas system for bioreactors - The invention relates to a waste gas system for bioreactors having a hydrophobic sterile filter, arranged at the end, and a heat exchanger which protects the sterile filter against blocking by liquid media. The gas outflow duct for discharging waste gas from a bioreactor vessel is divided in a cooling zone of the heat exchanger into a multiplicity of subducts and is extended in a heating zone of the heat exchanger to a calming zone. Due to the multiplicity of subducts, a considerably larger surface area for the removal of heat from the waste gas is available, with the result that in the case of laminar flow of the waste gas through the subducts a high effectiveness of the separation of liquids from the waste gas can be achieved. In the heating zone, the waste gas can heat up again due to the reduced flow rate until it reaches the hydrophobic sterile filter by way of taking up heat from the surroundings to a such a degree that the relative vapor contents are below 100% and separation of liquids from residual vapors at or in the hydrophobic sterile filter is precluded. | 07-08-2010 |
| 20110014075 | HOSE SYSTEM - A hose system has a pump hose with a hose portion insertable into a pump head of a hose pump. The hose portion has at least a first stop element fixing the hose portion in the feed direction. The first stop element can subsequently be connected immovably to the pump hose at a predefinable position of the pump hose. Thus, the pump hose can be used more universally and can be adapted to different pump heads. | 01-20-2011 |
| 20110038222 | MIXING VESSEL - A mixing vessel includes a flexible container, elements for mixing its contents, aeration elements, a drain/lower bearing port having a rigid flange provided with a drain passage, attached in a tight manner to the lower portion of the container wall, supporting a lower bearing that is adjacent to the drain passage. The vessel includes an extended element for dispensing aeration gas and is spaced essentially radially from the drain/bearing port; at least one tubular element for dispensing aeration gas extends from the extended dispensing element, in the inside space, along the inside surface of the lower portion and the side portion of the wall of the container and extends on the outside of the container from the upper portion; at least one mixing element is spaced essentially from the lower portion of the container wall, from the lower bearing, and from at least one extended element for dispensing aeration gas. | 02-17-2011 |
| 20110120151 | SYSTEMS AND METHODS FOR USE IN FREEZING, THAWING, AND STORING BIOPHARMACEUTICAL MATERIALS - A system for use in freezing, thawing, transporting or storing biopharmaceutical materials which includes a container, a holder and plurality of heat transfer members. The container is configured to hold biopharmaceutical materials therein. The holder has a cavity for receiving the container and includes an interior surface bounding the cavity. A plurality of pockets contact outer surfaces of the container and is received in the cavity. Each pocket of the plurality of pockets includes a pocket cavity. A heat transfer member actively controls the temperature of biopharmaceutical materials held in the container and is received in the pocket cavity. | 05-26-2011 |
| 20110120667 | SYSTEMS AND METHODS FOR USE IN FREEZING, THAWING, AND STORING BIOPHARMACEUTICAL MATERIALS - A system for use in freezing, thawing, transporting or storing biopharmaceutical materials which includes a container, a holder and plurality of heat transfer members. The container is configured to hold biopharmaceutical materials therein. The holder has a cavity for receiving the container and includes an interior surface bounding the cavity. A plurality of pockets contact outer surfaces of the container and is received in the cavity. Each pocket of the plurality of pockets includes a pocket cavity. A heat transfer member actively controls the temperature of biopharmaceutical materials held in the container and is received in the pocket cavity. | 05-26-2011 |
| 20110148597 | Dosing System and Method for the Dosing of a Medium - A dosing system and a method for dosing a medium, having a dosing control unit ( | 06-23-2011 |
