Osborne, FL
Carl G. Osborne, Jacksonville, FL US
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20100009981 | Tetracycline Derivatives with Reduced Antibiotic Activity and Neuroprotective Benefits - The present disclosure is directed to compositions and methods which utilize the tetracycline scaffold, preferably the scaffold of tetracycline or minocycline, and which significantly lack antibiotic activity. The compounds have neuroprotective attributes without interfering with the drugs capacity to pass through the blood brain barrier. These compounds have neuroprotective activity because of their inhibition of neuronal cell cycle progression. The compounds are characterized in part by a fifth ring joining positions 9 and 10. | 01-14-2010 |
20130123217 | TETRACYCLINE DERIVATIVES WITH REDUCED ANTIBIOTIC ACTIVITY AND NEUROPROTECTIVE BENEFITS - The present disclosure is directed to compositions and methods which utilize the tetracycline scaffold, preferably the scaffold of tetracycline or minocycline, and which significantly lack antibiotic activity. The compounds have neuroprotective attributes without interfering with the drugs capacity to pass through the blood brain barrier. These compounds have neuroprotective activity because of their inhibition of neuronal cell cycle progression. The compounds are characterized in part by a fifth ring joining positions 9 and 10. | 05-16-2013 |
Dan Osborne, Gulfport, FL US
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20120199233 | REPAIR APPARATUS AND METHOD - A repair device may include a cured-in-place liner having a modification to prevent adhesion of the liner adjacent to an opening in a pipe during the curing process and where a fire activated device has previously been installed/located. The liner may also soften and give way under specific time/temperature exposure that permits an existing fire-stop device to function properly and as designed in a fire event while preventing that device from deploying prematurely and/or by failure of the existing strap, fitting and/or other design deficiency. | 08-09-2012 |
Daniel E. Osborne, Naples, FL US
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20090113823 | OFF-RIDGE ROOF VENT - An off-ridge vent for a roof may comprise a longitudinally-extending main body having an arcuate lateral cross-sectional shape with two ends, a front flange extending from one lateral side of the main body, and a rear flange extending the other lateral side of the main body; two end caps, each end cap attached to and closing one of the ends of the main body, each end cap including a face portion which attaches to the main body and a side flange extending from the face portion; wherein, at least one of the end caps comprises a vented portion. The rear flange of the main body and the side flanges of the end caps may comprise return flanges that assist in redirecting any water that contacts the flange. The vent may overlay an aperture in the roof such that air may flow through the aperture and out the axial vent ends. | 05-07-2009 |
Jason Lee Osborne, Napies, FL US
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20120115728 | COMPOSITIONS CONTAINING ANTHRAQUINONE DERIVATIVES AS GROWTH PROMOTERS AND ANTIFUNGAL AGENTS - Compositions for modulating plant growth, seed germination and soil borne diseases comprising anthraquinone derivatives are disclosed. | 05-10-2012 |
Joel Osborne, Port Orange, FL US
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20110067781 | AUTOMATED WORKSTATION FOR THE SECURE PREPARATION OF A FINAL PRODUCT FOR MEDICAL OR PHARMACEUTICAL USE - An automated workstation ( | 03-24-2011 |
Joel A. Osborne, Port Orange, FL US
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20100097465 | AUTOMATED DRUG PREPARATION APPARATUS INCLUDING SYRINGE LOADING, PREPARATION AND FILLING - An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device. The system includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time. | 04-22-2010 |
20100100234 | AUTOMATED DRUG PREPARATION APPARATUS INCLUDING SYRINGE LOADING, PREPARATION AND FILLING - An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device. The system includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time. | 04-22-2010 |
20100161113 | AUTOMATED DRUG PREPARATION APPARATUS INCLUDING DRUG RECONSTITUTION - An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time. | 06-24-2010 |
20100217431 | AUTOMATED DRUG PREPARATION APPARATUS INCLUDING AUTOMATED DRUG RECONSTITUTION - An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time. | 08-26-2010 |
20130000250 | AUTOMATED DRUG PREPARATION APPARATUS INCLUDING AUTOMATED DRUG RECONSTITUTION - An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time. | 01-03-2013 |
20140290796 | AUTOMATED DRUG PREPARATION APPARATUS INCLUDING AUTOMATED DRUG RECONSTITUTION - An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time. | 10-02-2014 |
20150205932 | DATA TRANSMISSION CAPTURE IN SUPPORT OF MEDICATION PREPARATION - A method and software interface enables selective processing of data transmissions containing one or more medication orders intended for a pharmacy. Data transmissions are monitored and parsed for prescribed information which is utilized to populate a prescribed data structure, The data structure and parsing rules can be associated with a specific source that can be determined from the data transmission. The parsed data is tested against an order database to determine suitability for automated handling. If suitable, the medication preparation system prepares the medications identified by the data. Those portions of the data that are not suited for automated handling are released (e.g., from the parser). Further verification can be performed by determining the source of the data transmission and verifying it as a valid source, Data transmissions can be monitored over a network, within a network component, or in cooperation with another software program. | 07-23-2015 |
20150278477 | DATA TRANSMISSION CAPTURE IN SUPPORT OF MEDICATION PREPARATION - A method and software interface enables selective processing of data transmissions containing one or more medication orders intended for a pharmacy. Data transmissions are monitored and parsed for prescribed information which is utilized to populate a prescribed data structure. The data structure and parsing rules can be associated with a specific source that can be determined from the data transmission. The parsed data is tested against an order database to determine suitability for automated handling. If suitable, the medication preparation system prepares the medications identified by the data. Those portions of the data that are not suited for automated handling are released (e.g., from the parser). Further verification can be performed by determining the source of the data transmission and verifying it as a valid source. Data transmissions can be monitored over a network, within a network component, or in cooperation with another software program. | 10-01-2015 |
Jonathan Osborne, Ft. Lauderdale, FL US
Patrick H. Osborne, Ft. Lauderdale, FL US
Randy Lance Osborne, Valrico, FL US
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20130340357 | Method and Apparatus for Attaching Temporary Lifting Members to an Existing Lifting Anchor - A hoisting assembly for precast concrete structures is provided. A shackle is joined to an embedded anchor member by a pin or bolt, and the shackle is provided with load bearing members to accommodate various loads in a manner that reduces risk of damage to concrete and provides for a more efficient anchor. | 12-26-2013 |
20140096459 | LIFTING AND BRACING SYSTEM FOR A WALL PANEL - A connector member and system is provided for selectively connecting to an anchor of a precast concrete structure. The connector member comprises arcuate members for rotating the anchor into a position of secure interconnection and serves as a force-transmitting device for contacting the anchor and associated features and structures. | 04-10-2014 |
Scott Douglas Osborne, Tampa, FL US
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20090121864 | DEVICES, SYSTEMS AND FUNCTIONALITY FOR FIELD PERSONNEL COMMUNICATION AND MANAGEMENT - Devices, systems and functionality are provided that enable communication with, tracking of and managing activity/movements of field personnel | 05-14-2009 |
Timothy Osborne, Merritt Island, FL US
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20140364460 | USE OF FATOSTATIN FOR TREATING CANCER HAVING A p53 MUTATION - Fatostatin, a recently described inhibitor of SREBP activation, significantly reduces the level of mutant p53 binding to the HMG-CoA reductase gene promoter. Further, fatostatin treatment had a dramatic effect on normalizing the abnormal 3D morphology of 3 strains of breast cancer cells: MDA-468 cells, MDA-231 cells, and SKBR3 cells. The results show a functional interaction with SREBPs as being critical for mutant p53-mediated upregulation of the mevalonate pathway genes. At a clinical level, inhibition of the mevalonate pathway, either alone or in combination with other therapies, offers a novel, safe and much needed therapeutic option for tumors bearing mutant p53. | 12-11-2014 |
Tom Osborne, Jupiter, FL US
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20130272794 | FLOOD WATER BARRIER - A flood barrier protection system has a first barrier support member having a channel therein. A second barrier member spaced from the first support member having a channel therein. A barrier member disposed within both channels is sealingly engageable with one surface of each the support member. The barrier member has a rigid front wall and a rigid rear wall spaced across a gap form each other to form a hollow body open at at least one end. An upper engaging portion and a lower engaging portion each extend from the hollow body in opposite directions. | 10-17-2013 |