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Ofer Yodfat, Maccabim-Reut IL

Ofer Yodfat, Maccabim-Reut IL

Patent application numberDescriptionPublished
20080214916Fluid Delivery With In Vivo Electrochemical Analyte Sensing - One or more therapeutic fluids, such as for example insulin can be delivered to a body. In addition or alternatively, the concentrations of one or more analytes can be measured in vivo. A feedback process can be used to regulate levels of the one or more analytes based on the measurements via delivery of the one or more therapeutic fluids. Related systems, apparatus, methods, and/or articles are also described.09-04-2008
20080215035Systems, devices and methods for sustained delivery of a therapeutic fluid - Embodiments of the present invention are directed to devices, systems and methods for delivering therapeutic fluid (e.g., insulin) into the body, including a skin adherable cradle, for retaining a therapeutic fluid dispenser for delivering a therapeutic fluid to a user.09-04-2008
20080234630Disposable Dispenser for Patient Infusion - Embodiments of the invention are directed to methods and systems associated with a disposable dispenser (09-25-2008
20080234663Method for Selecting Bolus Doses in a Drug Delivery System - A method, apparatus and system for selecting a bolus dose of a drug in a drug delivery device is disclosed. The method comprises selecting the bolus dose from a pre-determined schedule of bolus doses, wherein each dose corresponds to a range of a body analyte levels.09-25-2008
20080255516Apparatus and method for pumping fluid - Methods, systems, and apparatuses for delivering therapeutic fluid to a user are disclosed. The apparatus includes a pump mechanism for pumping therapeutic fluid to the user having a reusable part which includes a housing and a disposable part configured to be inserted into the housing of the reusable part and to be connected with the reusable part. The connection of the reusable part and the disposable part enables operation of the pump mechanism and disconnection of the reusable part and the disposable part disables operation of the pump mechanism10-16-2008
20080281290Reciprocating Delivery Of Fluids To The Body With Analyte Concentration Monitoring - A volume of an analyte-enriched fluid can be withdrawn out of a user's subcutaneous compartment using a patch unit that includes a reversible pumping mechanism. The volume can be withdrawn out of the body and into the patch unit through a cannula inserted into the subcutaneous compartment so that an analyte concentration in the volume can be measured using a sensing element within the patch unit. After analyte concentration analysis, at least the volume can be delivered back into the subcutaneous compartment by operating the pumping mechanism in a forward direction. biologically compatible fluid can optionally be pumped into the subcutaneous compartment from a reservoir in the patch unit and then allowed to partially or completely equilibrate with the analyte concentration in the interstitial fluid of the subcutaneous compartment via a permeable or semi-permeable cannula surface before being drawn back into the patch unit for analysis. Related systems, apparatus, methods, and/or articles are also described.11-13-2008
20080319381Method System and Device for Assessing Insulin Sensitivity - A method and a system for determining insulin sensitivity (IS) is described. In one aspect the method and the system can be implemented by receiving a first parameter corresponding to an insulin dose in a subcutaneous tissue; applying a first kinetic model to obtain a plasma insulin concentration based on the first parameter; receiving a second parameter corresponding to a plasma glucose concentration; determining the insulin sensitivity (IS) based on the plasma insulin concentration and the second parameter.12-25-2008
20080319384Tailored Basal Insulin Delivery System and Method - Disclosed is a system to deliver insulin to a user's body. The system includes a dispensing unit to deliver the insulin to the body, and a control mechanism to control delivery of basal insulin according to a predetermined basal infusion pattern, the basal infusion pattern selected from a plurality of predetermined basal infusion patterns. In some embodiments, selection of the basal infusion pattern may be based on one or more personal characteristics of the user.12-25-2008
20080319394Portable infusion device with reduced level of operational noise - An infusion system, method and device for infusing therapeutic fluid into the body of a patient are provided. The device includes a driving mechanism including a plurality of gears, wherein at least one gear is adjacent to another gear. The device includes a gear in the plurality of gears having plurality of teeth and at least another gear in the plurality of gears having a plurality of teeth. The plurality of teeth of another gear interact with the plurality of teeth of the gear. At least one tooth in the plurality of teeth of the gear is elastically deformable for causing at least one tooth to elastically deform upon meshing with a tooth in the plurality of teeth of another gear and further for causing reduction of noise associated with operation of the driving mechanism.12-25-2008
20080319414Insertion device - An insertion apparatus and a method for use with a device for delivery of a therapeutic fluid into a body of a patient and/or for sensing of a bodily analyte are disclosed. The apparatus includes a housing adapted for loading therein at least one cannula cartridge unit having a protective member. The protective member accommodates at least one penetrating cartridge having a subcutaneously insertable element and a penetrating member. The apparatus includes a displacement mechanism capable of protracting the penetrating cartridge towards the body of the patient, where protraction of the penetrating cartridge results in insertion of the subcutaneously insertable element into the body of the patient.12-25-2008
20080319416Protector apparatus - An apparatus and a method for use with a device for delivery of a therapeutic fluid into a body of a patient and/or for sensing of a bodily analyte are disclosed. The apparatus is adapted for accommodating at least one subcutaneously insertable element and at least one penetrating member for penetrating the skin of the patient. The apparatus includes a protective member having an elongate body from which the subcutaneously insertable element and the penetrating member can be protracted to penetrate the skin of the patient and into which the penetrating member can be retracted subsequent to the penetrating, thereby retaining the subcutaneously insertable element in the body of the patient.12-25-2008
20090018406Method and Device for Assessing Carbohydrate-to-Insulin Ratio - A system and a method for determining an assessed carbohydrate to insulin ratio of a patient is described. The system and the method can comprise a memory component adapted for storing an initial set of values comprising at least one of a blood glucose level, a target blood glucose level, an insulin sensitivity, and, an estimated carbohydrate to insulin ratio. The system and the method can also comprise a bolus selection component adapted for selecting a test bolus corresponding to the determined initial set of values and a planned meal. In one implementation, the bolus selection component can receive bolus dose input from a user. In another implementation, the bolus selection component can estimate the bolus dose using a set of available inputs (e.g. the amount of carbohydrates in the planned meal). The system and the method can further comprise a user interface component adapted for receiving a confirmation that the test bolus has been administered to the patient. In some implementations, the user interface component can be adapted for selecting a meal of a known content.01-15-2009
20090030398Device and method for preventing hypoglycemia - A device and a method are provided that can be used for prevention of hypoglycemia. In one aspect, a device and a method for prevention of hypoglycemia can comprise receiving a target blood glucose (TBG) level corresponding to a desired level of glucose in a patient's body during a fasting time period; receiving a bedtime blood glucose (BBG) level corresponding to the level of glucose in the patient's body substantially at the beginning of the fasting time period; receiving a first set of parameters corresponding to a medical state of the patient; providing the levels of the TBG, BBG and the medical state of the patent to a therapeutic course of action determining means; and, providing means for administering the therapeutic course of action to the patient.01-29-2009
20090048152Systems and Methods for Glycemic Control During Pump Disconnection - Techniques and devices are described for allowing a diabetes patient to safely disconnect an insulin infusion system device for a time period. In one aspect, the techniques and devices can be implemented by receiving a maximum glucose amount, a minimum glucose amount, and a contemplated disconnection time; receiving a current glucose amount of the user; determining an expected increase in glucose of the user based on the contemplated disconnection time, an insulin sensitivity of the user and a contemplated basal insulin dose; validating the contemplated disconnection time based on at least one of the expected increase in glucose, the maximum glucose amount, and the minimum glucose amount; and, administering a therapeutic action to the user based on the validation of the contemplated disconnection time.02-19-2009
20100106088PORTABLE INFUSION PUMP WITH CANNULA INSERTER AND PAIN REDUCTION MECHANISM - An apparatus for insertion of a subcutaneously insertable element within a body of a patient is described: The apparatus is used for delivery of a therapeutic fluid into a body of a patient and/or sensing of a bodily analyte The apparatus allows alleviating of pain associated with the penetrating of the skin of the patient during needle insertion.04-29-2010
20100121306COLLAPSIBLE RESERVOIR FOR USE WITH A DELIVERY DEVICE - Disclosed is a therapeutic fluid reservoir to be used with an ambulatory portable infusion device. The reservoir includes a pliable shell defining a varying inner volume that varies based on the volume of therapeutic fluid held inside the reservoir, the varying inner volume having a predetermined maximum volume for containing a corresponding volume of therapeutic fluid and an outlet port for communicating fluid from the reservoir to a patient, the varying inner volume decreasing upon therapeutic fluid being communicated through the outlet port. Upon the reservoir reaching the predetermined maximum volume when being filled with therapeutic fluid, any therapeutic fluid in excess of the predetermined maximum volume driven into the reservoir causes a substantially corresponding amount of therapeutic fluid to exit out of the reservoir via the outlet port and/or at least one other port provided in the pliable shell.05-13-2010
20100130931FLUID DELIVERY DEVICE - A method and an apparatus for delivery of a therapeutic fluid to the body of a patient are provided. The apparatus includes a dispensing unit having a driving mechanism and a pumping mechanism for pumping the fluid to the body of the patient and a collapsible reservoir fillable with the therapeutic fluid for delivery thereof to the body of the patient.05-27-2010
20100130932POSITIVE DISPLACEMENT PUMP - Systems, methods and apparatuses for delivering therapeutic fluid to the body of a patient are disclosed. The apparatus includes a dispensing unit having a driving mechanism, a pumping mechanism, a reservoir containing therapeutic fluid, and an outlet port. The driving mechanism causes the pumping mechanism to positively displace therapeutic fluid within the reservoir for delivery of therapeutic fluid to the body of the patient via the outlet port.05-27-2010
20100137695DEVICE FOR METHOD FACILITATING INFUSION OF THERAPEUTIC FLUIDS AND SENSING OF BODILY ANALYTES - Disclosed is an assembly for use with a portable therapeutic device. The assembly includes a mounting housing securable to skin of a patient, and a cannula subcutaneously insertable through a passageway provided within the housing. The cannula is configured to be inserted subsequent to securing of the housing to the skin of the patient.06-03-2010
20100137790DETACHABLE PORTABLE INFUSION DEVICE - A portable therapeutic apparatus and a method for controlling the apparatus are provided. In one aspect the apparatus and the method can be implemented using a patch unit (06-03-2010
20100137802METHODS AND APPRATUS FOR MONITORING ROTATION OF AN INFUSION PUMP DRIVING MECHANISM - An infusion system, method and device for delivering therapeutic fluid to the body of a patient are disclosed. The device includes a dispensing unit having a peristaltic pump for dispensing therapeutic fluid to the body of the patient. The peristaltic pump includes a driving mechanism. The device further includes a monitoring mechanism (06-03-2010
20100145276PORTABLE INFUSION DEVICE WITH MEANS FOR MONITORING AND CONTROLLING FLUID DELIVERY06-10-2010
20100145303DEVICE FOR DRUG DELIVERY - Delivery of more than one therapeutic fluid as a means to control symptoms of a health conditions is disclosed. More than one therapeutic fluid may be dispensed from more than one reservoir and delivered to a user's body via one or more cannula that penetrate the skin. The therapeutic fluids may be delivered by action of one or more pumping mechanisms that may be controlled by a processor in a portable, ambulatory device. The therapeutic fluids may optionally be insulin and one or more of an amylin analog, pramlintide acetate and an exenatide, and the health condition may optionally be diabetes.06-10-2010
20100174239Tubing for Fluid Delivery Device - Delivery tubes having a flexible portion and pump mechanisms (07-08-2010
20100191078ENERGY SUPPLY FOR FLUID DISPENSING DEVICE - Disclosed is a portable fluid dispensing device for infusing a fluid into the body of a user and/or for sensing an analyte within the body. The device includes at least one housing to retain a source of energy to energize the device, the source of energy comprising at least one electrochemical cell to produce electrical energy upon exposure of the cell to air, and a seal to prevent exposure of the at least one cell to air when the source of energy is not in use and to enable exposure of the at least one cell to air prior to energizing the device with the source of energy. The at least one housing includes an opening to provide access to the seal to enable actuation of the seal to control exposure of the at least one cell to air.07-29-2010
20100198187VENTED DISPENSING DEVICE AND METHOD - Disclosed is a fluid dispensing device that includes at least one reservoir to hold the therapeutic fluid, at least one other unit requiring communication with ambient air, at least partly, to operate, and at least one housing defining an interior to retain the at least one reservoir and the at least one other unit. The at least one housing has at least one vent port formed on one or more of its walls. The at least one vent port is adapted to direct or communicate air to maintain pressure equilibrium between the air pressure in the interior of the at least one housing and the ambient air pressure outside the at least one housing, and provide communication with the ambient air to the at least one other unit requiring air to enable operation of the at least one other unit.08-05-2010
20100204657MANUALLY OPERABLE PORTABLE DEVICE - A portable therapeutic fluid delivery device and a method for delivering a therapeutic fluid into a body of a patient are provided. In one aspect the therapeutic fluid delivery device and the method can be implemented using at least one housing securable to the body of the patient, a reservoir coupled to the at least one housing, a therapeutic fluid dispensing mechanism, a memory component, a controller, at least one bolus delivery button configured to signal the controller to initiate the delivery of the therapeutic fluid into the body of the patient; and, an inadvertent initiation prevention mechanism adapted for preventing the patient from activating the at least one bolus delivery button.08-12-2010
20100217105Insertion device and method for inserting a subcutaneously insertable element into body - An insertion device (08-26-2010
20100217230Systems, Devices and Methods for Fluid/Drug Delivery - Fluid delivery systems, methods and devices for delivering a therapeutic fluid to the body of the patient are disclosed. A fluid delivery device for delivering fluid to the body of the patient includes a housing having an upper wall and a lower wall, wherein the upper wall includes an upper opening and the lower wall includes a lower opening, a well-arrangement mechanism configured to be disposed inside the housing and between the upper wall and the lower wall and including a tubular member having a bore, wherein the bore is configured to be disposed between the upper opening and the lower opening, and a penetrating cartridge for delivery of therapeutic fluid to the body of the patient, wherein the penetrating cartridge is configured to engage the bore following its insertion through the upper opening and the lower opening, wherein therapeutic fluid is configured to be delivered through the tubular member into the penetrating cartridge into the body of the patient when the penetrating cartridge engages the bore.08-26-2010
20100241086Flluid deliver system with electrochemical sensing of analyte concentration levels - A system and a method for delivering fluid to and sensing analyte levels in the body of the patient are disclosed. The system includes a dispensing apparatus configured to infuse fluid into the body of the patient and a sensing apparatus configured to be in communication with the dispensing apparatus and further configured to detect a level of analyte concentration in the body of the patient upon diffusion of the analyte into the fluid to be dispensed by the dispensing apparatus.09-23-2010
20100243099METHODS AND DEVICES FOR DELIVERING FLUID TO A RESERVOIR OF A FLUID DELIVERY DEVICE - Medical devices and methods for delivering therapeutic fluids transcutaneously to a body of a patient via a fluid delivery device and an adapter is provided. A Luer slip connector is provided at a first connecting end of the adapter. A therapeutic fluid container is connected with the second connecting end such that the container's neck is received in the second connecting end and a hollow penetrating member provided in the adapter punctures the septum of the container to admit the therapeutic fluid into a needle-less syringe from the container. After, fluid emerges from the tip of the penetrating member, the second connecting end of the adapter is attached to the fluid delivery device, thereby filling the reservoir with the fluid and pushing the syringe plunger forward to inject fluid into reservoir.09-30-2010
20100249558Hypodermic Optical Monitoring of Bodily Analyte - Disclosed is a skin adherable device for monitoring analytes in interstitial fluid. The device includes an electromagnetic radiation emitting source and a transmitter for transmitting the electromagnetic radiation between the electromagnetic radiation emitting source and the interstitial fluid. The device further includes a detector, operating electronics and a power supply. The device may include a reusable part and a disposable part.09-30-2010
20100268043Device and Method for Preventing Diabetic Complications - Methods, systems and devices for preventing diabetic complications are provided. In some embodiments, methods, systems and devices can be implemented using at least one subcutaneously insertable element, the element having a proximal portion and a distal portion, the proximal portion coupled to the housing, the distal portion configured for subcutaneous placement within a human body; a plurality of electrodes coupled to the distal portion of the at least one subcutaneously insertable element; and, a processor adapted to correlate a signal received from the plurality of electrodes to a concentration of ketone in the human body.10-21-2010
20100274218COMMUNICATIONS FOR MEDICINAL FLUID DELIVERY SYSTEM - Disclosed are methods, devices, systems and computer program products for communicating between at least one unit of a therapeutic fluid dispensing device and at least another unit of the dispensing device. The method includes performing a determination whether a first frequency can be used to transmit a message related to operations of the dispensing device, and transmitting the message based on the determination.10-28-2010
20100280499SYSTEM AND METHOD FOR GLYCEMIC CONTROL - Disclosed is a glucose monitoring system. The system includes a glucose sensor to periodically perform a plurality of glucose measurements in interstitial fluid, and a processor to determine one or more HbA1c values representative of a patient's glycosylated hemoglobin levels based on the periodic glucose measurements. In some embodiments, the glucose sensor is coupled to a therapeutic fluid (e.g., insulin) dispensing pump.11-04-2010
20100286601MAINTAINING GLYCEMIC CONTROL DURING EXERCISE - Devices, apparatuses and methods for controlling blood-glucose levels during exercise are described. For example, an insulin infusion apparatus can include a control module to regulate a rate of therapeutic fluid release into a body of a patient based on a determined therapeutic fluid requirement profile, and a dispensing unit to release therapeutic fluid at the regulated rate. The methods and devices can be implemented by receiving a first value corresponding to a first glucose concentration before an exercise activity of a user; receiving a second value corresponding to a second glucose concentration after the exercise activity for the user; determining a glucose concentration change based on a difference between the second value and the first value; modifying a basal rate based on a comparison of the glucose concentration change with a predetermined threshold value; and, recording the modified basal rate in a computer-readable memory device.11-11-2010
20100292651DEVICE FOR DRUG DELIVERY - Disclosed is an ambulatory therapeutic fluid delivery device (11-18-2010
20110004160Devices and Methods for Powering a Medical Device - Devices and methods for powering a medical device for sustained delivery of fluids or continuous monitoring of body analyte. The devices may comprise a pumping mechanism, a driving mechanism for activating the pumping mechanism to dispense fluid, and a power source coupled to the driving mechanism and having an energy storage cell for providing a pulsed power to the driving mechanism. The methods may be implemented by activating the driving mechanism using pulsed energy in the form of at least one pulse train pattern accumulated in and discharged from an energy storage component.01-06-2011
20110112696Fluid Delivery Device and Methods of Its Operation - A medicinal fluid delivery device and methods for its use are provided. The device can include a command means and a dispensing unit that can include a reusable part and a disposable, reservoir part. Software can be included that facilitates pairing and communications between a command means and the dispensing unit.05-12-2011
20110160652MODULAR SKIN-ADHERABLE SYSTEM FOR MEDICAL FLUID DELIVERY - Disclosed is a portable therapeutic fluid dispensing device. The fluid dispensing device includes a reusable part (06-30-2011

Patent applications by Ofer Yodfat, Maccabim-Reut IL