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Noujaim
Antoine Noujaim, Edmonton CA
| Patent application number | Description | Published |
|---|---|---|
| 20080206318 | Therapeutic compositions that alter the immune response - The invention is therapeutic methods and compositions that alter the immunogenicity of the host. | 08-28-2008 |
| 20080220012 | Therapeutic Compositions that alter the immune response - The invention is therapeutic methods and compositions that alter the immunogenicity of the host. | 09-11-2008 |
| 20090312404 | Cleavable Carnitine Compound - The invention includes novel compounds, including but not limited to formula A and formula B, and an improved delivery method. These compounds and methods are useful in preventing or treating diseases or conditions associated with or caused by the presence of free radicals, and are useful for increasing cellular metabolism while simultaneously alleviating the resultant increase in oxidative stress. Specifically, a carnitine is bound to a lipoic acid derivative or to dihydrolipoic acid or its derivatives using a hydrolysable linker to form a single compound. | 12-17-2009 |
Antoine Noujaim, Alberta CA
| Patent application number | Description | Published |
|---|---|---|
| 20110189180 | ANTIGENIC COMPOSITIONS AND USE OF SAME IN THE TARGETED DELIVERY OF NUCLEIC ACIDS - Methods and compositions are provided for delivery of therapeutic nucleic acids to a target cell. A chimeric antigen is provided to encapsulate, bind, or otherwise carry a nucleic acid molecule to a target cell where the chimeric antigen and nucleic acid are internalized by receptor-mediated endocytosis. The chimeric antigen has a nucleic acid interaction domain, a target binding domain, and an immune response domain that may include a target antigen. Targeting is generally provided by the specificity of the target binding domain for a particular target cell receptor, but may also be provided by inclusion of a targeting antigen within the immune response domain. The combined delivery of chimeric antigen and nucleic acid, which may be a siRNA, may be synergistic in certain applications, for example in breaking host tolerance to a virus or in providing immunostimulation. | 08-04-2011 |
Antoine A. Noujaim, Edmonton CA
| Patent application number | Description | Published |
|---|---|---|
| 20080311127 | Combination therapy for treating disease - Disclosed are methods for treating cancer comprising administering a xenotypic antibody and a chemotherapeutic drug to a patient suffering from cancer. Also disclosed is a method for inducing a host immune response in a patient against a multi-epitopic in vivo tumor antigen present in the host serum, which antigen does not elicit an effective host immune response, comprising administering to the patient a chemotherapeutic drug and a composition comprising a binding agent that specifically binds to a first epitope on the antigen and allowing the binding agent to form a binding agent/antigen pair, wherein an effective host immune response is elicited against a second epitope on the antigen. | 12-18-2008 |
| 20090202560 | Method for diagnosing efficacy of xenotypic antibody therapy - The invention concerns methods and compositions for intiating and/or enhancing an immune response by contacting a binding reagent with a soluble antigen, wherein the binding reagent-antigen pair generates an immune response to the antigen. | 08-13-2009 |
| 20090220493 | Reagents and methods for inducing an immune response to prostate specific antigen - The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen. | 09-03-2009 |
| 20090238822 | Chimeric Hepatitis C Virus Antigens For Eliciting an Immune Response - Disclosed herein are chimeric antigens, comprising an hepatitis C virus (HCV) antigen and a Fc fragment of an immunoglobulin for eliciting an immune response against said antigen. The immune response is enhanced by presenting the host immune system with an immune response domain (HCV antigen from HCV core, envelope, or non-structural protein fragments) and a target binding domain (an Fc fragment). By virtue of the target binding domain, antigen presenting cells internalize and process the chimeric antigens for antigen presentation, thereby eliciting both a humoral and cellular immune response. | 09-24-2009 |
Majed Noujaim, Manchester, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080251503 | MODULAR PLASMA SPRAY GUN - The present invention provides a modular plasma spray gun including a sleeve, a core, and a water tube connectable to the sleeve. The sleeve has a cylindrical sidewall defining a central opening through a length thereof for receiving the core. The sleeve includes a mounting member for mounting the sleeve and an associated spray gun to a spray gun manipulator. The core receives an anode housing and is removably disposed in the central opening of the sleeve and includes forward and rearward portions defined by a stepped central bore through a length thereof. The forward portion receives an anode housing therein, the rearward portion for carrying coolant to and from the anode housing. The coolant inlet tube, coolant outlet tube, and gas inlet tube are manually detachable from an opening in the plasma spray gun assembly and have manually removable locks to prevent tube detachment. | 10-16-2008 |
Sharbel Noujaim, Menlo Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100130838 | Infrared Temperature Measurement of Strip - Provided are systems and methods that permit the direct assessment of temperature on an electrochemical test strip, including at the reaction site of the strip, through the inclusion of an infrared sensor within the biosensing instrument. Analyte measurement systems are provided in which an infrared sensor is used to assess temperature associated with a test strip, and the acquired temperature data is used to modulate data regarding an analyte in a biological sample, thereby providing a more accurate measurement of the analyte. | 05-27-2010 |
Sharbel E. Noujaim, Menlo Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080208026 | SYSTEMS AND METHODS FOR DETECTING HYPOGLYCEMIC EVENTS HAVING A REDUCED INCIDENCE OF FALSE ALARMS - The present invention is directed to a method of reducing false readings in a hypoglycemic detector that includes establishing a predetermined hypoglycemic threshold, a predetermined critical threshold, a predetermined rate of change in glucose concentration where the predetermined critical threshold is below the predetermined hypoglycemic threshold. A first sampling rate is then calculated based upon said predetermined hypoglycemic threshold, said predetermined critical threshold, and said predetermined rate of change in glucose concentration. | 08-28-2008 |