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Northrup, US
Alan Northrup, Reading, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100160309 | INHIBITORS OF JANUS KINASES AND/OR 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 - The instant invention provides for compounds that inhibit JAK2 tyrosine kinase and/or PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting JAK2 tyrosine kinase activity and/or PDK1 kinase inhibitory activity by administering the compound to a patient in need of treatment or prevention of myeloproliferative disorders or cancer. | 06-24-2010 |
| 20100197634 | INHIBITORS OF JANUS KINASES - The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer. | 08-05-2010 |
Alan B. Northrup, Reading, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090012076 | Tyrosine kinase inhibitors - The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 01-08-2009 |
| 20090131423 | Tyrosine Kinase Inhibitors - The present invention relates to imidazo[1,2-a]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 05-21-2009 |
| 20090156617 | Tyrosine kinase inhibitors - The present invention relates to imidazo[1,2-a]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 06-18-2009 |
| 20090203684 | Tyrosine kinase inhibitors - The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives of formula (I) that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 08-13-2009 |
| 20090291941 | Tyrosine Kinase Inhibitors - The present invention relates to pyrido[3,2-c]benzazocinone derivatives and related compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 11-26-2009 |
Alan B. Northrup, Us Residency Reading, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110230500 | Inhibitors of Phosphoinositide Dependent Kinase 1 (PDK1) - The instant invention provides for compounds that inhibit PDK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting PDK1 activity by administering the compound to a patient in need of treatment of cancer. | 09-22-2011 |
Charles J. Northrup, Old Bridge, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090300192 | Subscription-Based Services - The present invention provides a virtual network, sitting “above” the physical connectivity and thereby providing the administrative controls necessary to link various communication devices via an Access-Method-Independent Exchange. In this sense, the Access-Method-Independent Exchange can be viewed as providing the logical connectivity required. In accordance with the present invention, connectivity is provided by a series of communication primitives designed to work with each of the specific communication devices in use. As new communication devices are developed, primitives can be added to the Access-Method-Independent Exchange to support these new devices without changing the application source code. A Thread Communication Service is provided, along with a Binding Service to link Communication Points. A Thread Directory Service is available, as well as a Broker Service and a Thread Communication Switching Service. Intraprocess, as well as Interprocess, services are available. Dynamic Configuration Management and a Configurable Application Program Service provide software which can be commoditized, as well as upgraded while in operation. | 12-03-2009 |
James Northrup, Draper, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20090016657 | Two-piece bearing housing for a centrifugal pump - A two-piece bearing housing is provided for use in centrifugal pumps having or requiring multiple chambers for enclosing or confining bearings or seals, and/or providing lubricant or coolant to the bearings and seals of the pump, the two-piece housing providing several improvements including the ability to make the two pieces from different materials, the reduction in scrap castings due to imprecision achieved in the casting process and improved structures in the housing for monitoring the lubricant chambers in the housing. | 01-15-2009 |
| 20090232639 | Wear plate for a centrifugal pump - A wear plate for use in a centrifugal pump is structured with at least one cutting element positioned at the inner bore of the wear plate, the cutting element or elements being positioned to impact the cutting edge of the vanes of an impeller and oriented in a direction relative to the rotation of the impeller so that the wear plate cutting element or elements can capture the solids in a processed fluid and hold them in place until the solids can be cut by the impeller vane or vanes, the wear plate cutting elements further being structured to be self-sharpening. | 09-17-2009 |
| 20100313972 | Check Valve For A Self-Priming Pump - A check valve of the flapper type structured for use in a self-primer pump is structured for attachment to the pump casing in a manner that facilitates servicing of the check valve, and includes securement means that are positioned external to the casing and a flapper that is located through an opening of the casing in a manner that enables the servicing of the valve without dropping the flapper or the hardware into the interior of the pump. | 12-16-2010 |
Marlan L. Northrup, Albuquerque, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20110139190 | Apparatus, method and system for substantially preventing mold in front loading washing machines - The present invention is generally directed to providing an apparatus, method or system for substantially or completely removing mold (and thus, odor) from a front loading washing machine. Briefly, the present invention may be described as a gasket air tee and may be further generally described as a venting apparatus or device having an elongated main portion and an elongated handle portion, the main portion being attached or otherwise integrated with the handle portion, the main portion further being in air flow communication with the handle portion. This apparatus may be used in a method or system for substantially preventing mold typically found within a gasket assembly in a front loading washing machine. | 06-16-2011 |
Ryan Northrup, Renton, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110231787 | GUI FOR PROGRAMMING STEP AND REPEAT OPERATIONS IN A MACHINE VISION INSPECTION SYSTEM - A method is provided for programming step and repeat operations of a machine vision inspection system. The machine vision inspection system includes an imaging portion, a stage for holding one or more workpieces in a field of view (FOV) of the imaging portion, a control portion, and a graphical user interface (GUI). According to the method, a user operates the machine vision inspection system to define a set of inspection operations to be performed on a first configuration of workpiece features. The user also operates the GUI to display a step and repeat dialog box, in which he defines a first plurality of parameters defining a set of default step and repeat locations for performing the defined set of inspection operations. The user further operates the GUI to define a set of inspection step and repeat locations, which is a subset of the defined set of default step and repeat locations, where the inspection operations are to be actually performed. | 09-22-2011 |