Patent application number | Description | Published |
20090012076 | Tyrosine kinase inhibitors - The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 01-08-2009 |
20090131423 | Tyrosine Kinase Inhibitors - The present invention relates to imidazo[1,2-a]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 05-21-2009 |
20090156617 | Tyrosine kinase inhibitors - The present invention relates to imidazo[1,2-a]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 06-18-2009 |
20090203684 | Tyrosine kinase inhibitors - The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives of formula (I) that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 08-13-2009 |
20090291941 | Tyrosine Kinase Inhibitors - The present invention relates to pyrido[3,2-c]benzazocinone derivatives and related compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 11-26-2009 |
20110245205 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 10-06-2011 |
20120277192 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 11-01-2012 |
20120309735 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 12-06-2012 |
20140100250 | PYRIDYL AMINOPYRIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer. | 04-10-2014 |
20140148474 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer. | 05-29-2014 |
20140243290 | Aminopyrimidines as SYK Inhibitors - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 08-28-2014 |
20140243336 | 2-Pyridyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors - The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase. | 08-28-2014 |
20140243337 | Phenyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors - The invention provides certain phenyl carboxamide-containing compounds of the Formula (I); or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase. | 08-28-2014 |
20140249130 | BIPYRIDYLAMINOPYRIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, or are prodrugs thereof, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer. | 09-04-2014 |
20140303206 | 3-Pyridyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors - The invention provides certain 3-pyridyl carboxamide-containing compounds of the Formula (I) (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase. | 10-09-2014 |
20150148327 | SUBSTITUTED PYRIDINE SPLEEN TYROSINE KINASE (SYK) INHIBITORS - The invention provides certain substituted pyridines of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R | 05-28-2015 |
20150175575 | IMIDAZOLYL ANALOGS AS SYK INHIBITORS - The present invention provides novel imidazole analogs of Formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer. | 06-25-2015 |
20150191461 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS - The present invention provides novel pyrazole derivatives of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer. | 07-09-2015 |
20150232428 | SUBSTITUTED PHENYL-SPLEEN TYROSINE KINASE (SYK) INHIBITORS - The invention provides certain substituted phenyl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R | 08-20-2015 |
20150239866 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS - Provided are triazole derivatives of Formula I which are potent inhibitors of spleen tyrosine kinase and pharmaceutical composition. The triazole derivatives are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer. | 08-27-2015 |
Patent application number | Description | Published |
20090016657 | Two-piece bearing housing for a centrifugal pump - A two-piece bearing housing is provided for use in centrifugal pumps having or requiring multiple chambers for enclosing or confining bearings or seals, and/or providing lubricant or coolant to the bearings and seals of the pump, the two-piece housing providing several improvements including the ability to make the two pieces from different materials, the reduction in scrap castings due to imprecision achieved in the casting process and improved structures in the housing for monitoring the lubricant chambers in the housing. | 01-15-2009 |
20090232639 | Wear plate for a centrifugal pump - A wear plate for use in a centrifugal pump is structured with at least one cutting element positioned at the inner bore of the wear plate, the cutting element or elements being positioned to impact the cutting edge of the vanes of an impeller and oriented in a direction relative to the rotation of the impeller so that the wear plate cutting element or elements can capture the solids in a processed fluid and hold them in place until the solids can be cut by the impeller vane or vanes, the wear plate cutting elements further being structured to be self-sharpening. | 09-17-2009 |
20100313972 | Check Valve For A Self-Priming Pump - A check valve of the flapper type structured for use in a self-primer pump is structured for attachment to the pump casing in a manner that facilitates servicing of the check valve, and includes securement means that are positioned external to the casing and a flapper that is located through an opening of the casing in a manner that enables the servicing of the valve without dropping the flapper or the hardware into the interior of the pump. | 12-16-2010 |
20110280714 | Two-Piece Bearing Housing For A Centrifugal Pump - A two-piece bearing housing is provided for use in centrifugal pumps having or requiring multiple chambers for enclosing or confining bearings or seals, and/or providing lubricant or coolant to the bearings and seals of the pump, the two-piece housing providing several improvements including the ability to make the two pieces from different materials, the reduction in scrap castings due to imprecision achieved in the casting process and improved structures in the housing for monitoring the lubricant chambers in the housing. | 11-17-2011 |
20120014783 | Apparatus For Non-Clogging Pumps - Improvements in the operation and maintenance of non-clogging pumps are provided which increase pump efficiencies through improved impeller design and vacuum assembly design, and which increase seal lubrication efficiencies through improved seal lubricant reservoir system design. | 01-19-2012 |
Patent application number | Description | Published |
20130344897 | SYSTEM AND METHOD FOR USER INTERACTION WITH VIRTUAL GEOGRAPHIC ZONES - A system and method for user interaction includes a network, a server connected to the network, an administrator device receiving information from a global positioning system and connected to the network, a user device receiving information from the global positioning system and connected to the network. The administrator, having the administrator device, defines a set of virtual geographic zones and sub-zones in which the user device is tracked, and saves the set of virtual geographic zones and sub-zones to an administrator account on the server. The user downloads a user application, sets-up a user account, and downloads the set of virtual geographic zones and sub-zones. As the user, having the user device, moves through the virtual geographic zones and sub-zones the location of the user device is determined and a set of administrator-defined actions are executed on the user device based on the location of the user device. | 12-26-2013 |
20140099975 | SYSTEM AND METHOD FOR PROVIDING AUTOMATIC SUPERVISION OF EMPLOYEES USING VIRTUAL GEOGRAPHIC ZONES - A system and method for user interaction includes a network, a server connected to the network, a supervisor device receiving information from a global positioning system and connected to the network, a user device receiving information from the global positioning system and connected to the network. The supervisor, having the supervisor device, defines a set of virtual geographic zones and sub-zones in which the user device is tracked, and saves the set of virtual geographic zones and sub-zones to a supervisor account on the server. The user downloads a user application, sets-up a user account, and downloads the set of virtual geographic zones and sub-zones. As the user, having the user device, moves through the virtual geographic zones and sub-zones the location of the user device is determined and a set of supervisor-defined actions are executed on the user device based on the location of the user device. | 04-10-2014 |
20140194192 | METHOD FOR AUTHENTICATING A WAGER USING A SYSTEM AND METHOD FOR INTERACTING WITH VIRTUAL GEOGRAPHIC ZONES - A system and method for user interaction includes a network, a server connected to the network, a supervisor device receiving information from a global positioning system and connected to the network, a user device receiving information from the global positioning system and connected to the network. The supervisor, having the supervisor device, defines a set of virtual geographic zones and sub-zones in which the user device is tracked, and saves the set of virtual geographic zones and sub-zones to a supervisor account on the server. The user downloads a user application, sets-up a user account, and downloads the set of virtual geographic zones and sub-zones. As the user, having the user device, moves through the virtual geographic zones and sub-zones the location of the user device is determined and a set of supervisor-defined actions are executed on the user device based on the location of the user device. | 07-10-2014 |
20140335478 | SYSTEM AND METHOD FOR MARKSMANSHIP TRAINING - A system and method for marksmanship training comprises a screen, a computer having a processor and a memory connected to the processor and adjacent the screen, a set of modified video images stored in the memory, a set of projectors for projecting the set of modified video images onto the screen, connected to the computer and adjacent the screen, the set of modified video images including a moving clay target image and a phantom clay target image adjacent the moving clay target image at a lead distance from the moving clay target image, a camera connected to the computer and adjacent the screen, a weapon adjacent the screen, and a laser operatively mounted in the weapon. The phantom clay target image has a contrast level range from a fully opaque image to a fully transparent image. | 11-13-2014 |
20140335479 | SYSTEM AND METHOD FOR MARKSMANSHIP TRAINING - A system and method for marksmanship training comprises a screen, a computer having a processor and a memory connected to the processor and adjacent the screen, a set of modified video images stored in the memory, a set of projectors for projecting the set of modified video images onto the screen, connected to the computer and adjacent the screen, the set of modified video images including a moving clay target image and a phantom clay target image adjacent the moving clay target image at a lead distance from the moving clay target image, a camera connected to the computer and adjacent the screen, a weapon adjacent the screen, and a laser operatively mounted in the weapon. The phantom clay target image has a contrast level range from a fully opaque image to a fully transparent image. | 11-13-2014 |
Patent application number | Description | Published |
20110231787 | GUI FOR PROGRAMMING STEP AND REPEAT OPERATIONS IN A MACHINE VISION INSPECTION SYSTEM - A method is provided for programming step and repeat operations of a machine vision inspection system. The machine vision inspection system includes an imaging portion, a stage for holding one or more workpieces in a field of view (FOV) of the imaging portion, a control portion, and a graphical user interface (GUI). According to the method, a user operates the machine vision inspection system to define a set of inspection operations to be performed on a first configuration of workpiece features. The user also operates the GUI to display a step and repeat dialog box, in which he defines a first plurality of parameters defining a set of default step and repeat locations for performing the defined set of inspection operations. The user further operates the GUI to define a set of inspection step and repeat locations, which is a subset of the defined set of default step and repeat locations, where the inspection operations are to be actually performed. | 09-22-2011 |
20130120567 | SYSTEM AND METHOD UTILIZING AN EDITING INITIALIZATION BLOCK IN A PART PROGRAM EDITING ENVIRONMENT IN A MACHINE VISION SYSTEM - A method is provided for defining and utilizing an editing initialization block for a part program. The part program comprises a plurality of steps for taking measurements of a part and is displayed in an editing interface. An option is provided in the editing interface for selecting which steps are in an editing initialization block. After the part program has been saved, at a later time when the part program is recalled for editing, the editing initialization block may be run before additional steps are added to the part program. At least some of the data that would have been obtained by one or more of the initial part program steps that are not in the editing initialization block may be based on estimated data that is related to (e.g., modified based on) data determined from running the editing initialization block. | 05-16-2013 |
20130123945 | MACHINE VISION SYSTEM PROGRAM EDITING ENVIRONMENT INCLUDING REAL TIME CONTEXT GENERATION FEATURES - A machine vision system program editing environment includes near real time context generation. Rather than requiring execution of all preceding instructions of a part program in order to generate a realistic context for subsequent edits, surrogate data operations using previously saved data replace execution of certain sets of instructions. The surrogate data may be saved during the actual execution of operations that are recorded in a part program. An edit mode of execution substitutes that data as a surrogate for executing the operations that would otherwise generate that data. Significant time savings may be achieved for context generation, such that editing occurs within an operating context which may be repeatedly refreshed for accuracy in near real time. This supports convenient program modification by relatively unskilled users, using the native user interface of the machine vision system, rather than difficult to use text-based or graphical object-based editing environments. | 05-16-2013 |
20130125044 | Machine Vision System Program Editing Environment Including Synchronized User Interface Features - A machine vision system program editing environment including synchronized selection and/or identification of related features in a plurality of different user interface windows is provided. In particular, one of the windows is an editing window where a part program representation is displayed for editing by a user. In one embodiment, a user may select data or another feature of interest in a window that is not the editing window (e.g., a results window, or graphical workpiece inspection feature display window) and the associated part program instruction representation is automatically highlighted and/or selected in the editing window. Conversely, a part program instruction representation may be selected by a user in the editing window and the associated results or feature in another window is automatically highlighted and/or selected. User interface navigation, rapid program quality assessment, and overall part program creation and editing efficiency are significantly enhanced in such an editing environment. | 05-16-2013 |
20140337775 | MACHINE VISION SYSTEM PROGRAM EDITING ENVIRONMENT INCLUDING OPERATING CONTEXT AWARE COPY AND PASTE FEATURE - A method is provided for copying and pasting a set of machine vision part program operations when editing a part program in a machine vision inspection system. The method includes: a) selecting at least a first instruction representation at a copy location in a displayed part program representation; b) performing copy operations by executing a first subset of modification operations directed to elements that are specific to a first operating context at the copy location, to thereby generate a partially modified selected instruction representation and/or its underlying instruction code; c) defining a paste location in the displayed part program representation; and d) performing paste operations by executing a second subset of modification operations directed to elements that are specific to a second operating context at the paste location, to thereby generate and paste onto the paste location a fully modified selected instruction representation and/or its underlying instruction code. | 11-13-2014 |
20140337780 | SYSTEM, GUI AND METHOD FOR EDITING STEP AND REPEAT OPERATION INSTRUCTIONS IN A MACHINE VISION INSPECTION SYSTEM - A system, a GUI and a method are provided that allow intuitive, flexible and robust editing of individually editable instructions generated by conversion operations applied to a defined step-and-repeat programming element in a machine vision inspection system. The method includes: a) Converting a defined step-and-repeat programming element to generate N independently-editable code blocks including an independently-editable substantial replication of a repeated operation block of the step-and-repeat element, each of code blocks executed at a respective location corresponding to a step and repeat location; b) Representing the code blocks in an editing GUI; and c) Eliminating the defined step-and-repeat programming element as an editable element. The defined step-and-repeat programming element may be represented in the editing GUI. The conversion operations may be initiated by a user activating a step and repeat conversion command directed to the defined step-and-repeat programming element. | 11-13-2014 |
20150103156 | SYSTEM AND METHOD FOR CONTROLLING A TRACKING AUTOFOCUS (TAF) SENSOR IN A MACHINE VISION INSPECTION SYSTEM - A method is provided for controlling a Tracking AutoFocus (TAF) portion of a machine vision inspection system including an imaging portion, a movable workpiece stage, a control portion, and graphical user interface (GUI). The TAF portion automatically adjusts a focus position of the imaging portion to focus at a Z height corresponding to a current surface height of the workpiece. The method includes providing the TAF portion, and providing TAF enable and disable operations, wherein: the TAF disable operations comprise a first set of TAF automatic interrupt operations that are automatically triggered by user-initiated operations that include changing the Z height, and the TAF disable operations may further comprise automatic interrupt operations that are automatically triggered based on at least one respective TAF Z height surface tracking characteristic exceeding a previously set TAF disable limit for that respective TAF Z height surface tracking characteristic. | 04-16-2015 |