| Patent application number | Description | Published |
| 20090275569 | Benzotriazine Inhibitors of Kinases - The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases. | 11-05-2009 |
| 20090275582 | Bi-Aryl Meta-Pyrimidine Inhibitors of Kinases - The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non-receptor kinases. | 11-05-2009 |
| 20090286789 | Bi-Aryl Meta-Pyrimidine Inhibitors of Kinases - The invention provides methods of treating a disease selected from systemic sclerosis, rheumatoid arthritis, mastocytosis, and chronic eosinophilic leukemia comprising administering biaryl meta-pyrimidine compounds having the general structure (A) to a subject in need thereof. The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the JAK kinase family, and various other specific receptor and non-receptor kinases. | 11-19-2009 |
| 20100278811 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF - Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as retinopathies or macular degeneration or other vitreoretinal diseases, inflammatory diseases, vascular leakage syndrome, edema, transplant rejection, adult/acute respiratory distress syndrome (ARDS), and the like. | 11-04-2010 |
| 20100330030 | Vasculostatic Agents and Methods of Use Thereof - Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as retinopathies or macular degeneration or other vitreoretinal diseases, inflammatory diseases, vascular leakage syndrome, edema, transplant rejection, adult/acute respiratory distress syndrome (ARDS), and the like. | 12-30-2010 |
| Patent application number | Description | Published |
| 20090008264 | SYSTEM AND METHOD FOR PROVIDING ELECTROCHEMICAL MACHINING OF A DEVICE - A system and method for electrochemically machining a work-piece contains a fixture capable of receiving a work-piece and securing the work-piece to the fixture. An electrolyte source is also provided. In addition, the system contains a rotary drive subassembly capable of receiving a portion of the work-piece therein, motion of the rotary drive assembly being determined by a received control signal, wherein frequency and amplitude of the control signal increases and decreases motion of the rotary drive subassembly, and wherein the control signal is a trapezoidal waveform. | 01-08-2009 |
| 20110318183 | Method for Producing a Shrouded Impeller from Two or More Components - Provided is a two-piece shrouded impeller, and methods for manufacturing and assembling a two-piece shrouded impeller. The two-piece shrouded impeller, in accordance with one embodiment, may have a one-piece partially shrouded impeller having a central hub, a number of blades integrally attached to the hub, and one or more integral partial shroud sections integrally attached to the blades. The two-piece shrouded impeller in this embodiment may also have a separate shroud section that attaches to the one-piece shrouded impeller, so that the separate shroud section and the partial shroud sections combine to form a completed shroud that covers the impeller blades. The separate shroud section may attach to the one-piece shrouded impeller with a snap joint, or with an interference fit, or using a squeeze deformable ring. Once attached, the shroud section may be bonded to the one-piece shrouded impeller by brazing, stick welding, ultrasonic welding, or electron beam welding. | 12-29-2011 |