Njardarson
Jon Njardarson, Ithaca, NY US
Patent application number | Description | Published |
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20090131691 | Production of 2,5-Dihydrofurans and Analogous Compounds - Vinyl oxiranes are rearranged to 2,5-dihydrofuran using catalyst (III) or (IV). The 2,5-dihydrofuran can be reduced to tetrahydrofuran. 3,4-Epoxy-1-butene substrate is converted to 2,5-dihydrofuran which in turn is converted to tetrahydrofuran. Substrate for making 3-methyltetrahydrofuran is prepared from isoprene. Substrate for making 2-methyltetrahydrofuran is prepared from piperylene. Reactions analogous to that with vinyl oxiranes are carried out with vinyl thiiranes and vinyl aziridines. | 05-21-2009 |
20140086831 | Single Wall Nanotube Constructs and Uses Thereof - The present invention provides soluble single wall nanotube (SWNT) constructs functionalized with a plurality of a targeting moiety and a plurality of one or more payload molecules attached thereto. The targeting moiety and the payload molecules may be attached to the soluble SWNT via a DNA or other oligomer platform attached to the SWNT. These soluble SWNT constructs may comprise a radionuclide or contrast agent and as such are effective as diagnostic and therapeutic agents. Methods provided herein are to diagnosing or locating a cancer, treating a cancer, eliciting an immune response against a cancer or delivering an anticancer drug in situ via an enzymatic nanofactory using the soluble SWNT constructs. | 03-27-2014 |
Jon T. Njardarson, Ithaca, NY US
Patent application number | Description | Published |
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20090124662 | Migrastatin analogs in the treatment of cancer - In one aspect, the present invention provides a method for treating colon and/or ovarian cancer in a subject comprising administering to a subject in need thereof a compound of general formula (I): wherein R1-R6, R, -R, Q, Y1, Y2 and n are as defined herein, wherein the compound is present in an amount effective to inhibit colon and/or ovarian tumor metastasis. | 05-14-2009 |
20110281916 | MIGRASTATIN ANALOGS AND USES THEREOF - The present invention provides compounds having formula (I): | 11-17-2011 |
20140011844 | MIGRASTATIN ANALOGS AND USES THEREOF - The present invention provides compounds having formula (I): | 01-09-2014 |
Jon T. Njardarson, Tucson, AZ US
Patent application number | Description | Published |
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20160042156 | METHOD AND SYSTEM FOR DRUG DESIGN - The present invention provides a method for conducting a drug discovery research by identifying a lead candidate based solely on drugs that have been approved for a clinical use by an agency who has the authority to approve a drug for clinical use in mammal. The method uses a cheminformatics database. The present invention also provides a method and system for analyzing chemical drugs that have been approved for clinical use. | 02-11-2016 |
Jön T. Njardarson, Ithaca, NY US
Patent application number | Description | Published |
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20110263653 | MIGRASTATIN ANALOG COMPOSITIONS AND USES THEREOF - In one aspect, the present invention provides pharmaceutical compositions comprising a therapeutically effective amount of a compound of general formula (I), | 10-27-2011 |