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Niu, US
Baohua Niu, Portland, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20120249859 | THROUGH SILICON IMAGING AND PROBING - Through silicon imaging and probing. A light source provides unpolarized light to be projected on a device under test (DUT). Light reflected from the DUT may be captured by a camera or other image capture device. A pellicle is utilized to reflect light from the light source toward the DUT. The pellicle also passes light reflected by the DUT to the camera. One or more linear polarizers or half wave plates may be used to provide the desired light polarization. The ability to provide the desired polarization provides an improved image that can be captured by the camera. | 10-04-2012 |
Bo Niu, Kearny, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090005028 | SUM RATE OF BROADCAST CHANNELS WITH OUTDATED 1-BIT FEEDBACK - A single-input single-output (SISO) downlink channel with K users is analyzed in the presence of Rayleigh flat fading. A limited channel state information (CSI) feedback scheme is included, where only an outdated 1-bit feedback per user is available at the base station for each fading block. A closed-form expression for the achievable ergodic sum-rate of the 1-bit feedback scheme is presented for any number of users, as a function of the fading temporal correlation coefficient, the threshold of the 1-bit CSI quantizer and the SNR. The sum-rate scales with increasing number of users as log logK, which is the same scaling law achieved by the optimal non-delayed full CSI feedback scheme. | 01-01-2009 |
Cheng Niu, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100082511 | JOINT RANKING MODEL FOR MULTILINGUAL WEB SEARCH - Described is a technology in which a classifier is built to rank documents of different languages found in a query based at least in part on similarity to other documents and the relevance of those other documents to the query. A joint ranking model, e.g., based upon a Boltzmann machine, is used to represent the content similarity among documents, and to help determine joint relevance probability for a set of documents. The relevant documents of one language are thus leveraged to improve the relevance estimation for documents of different languages. In one aspect, a hidden layer of units (neurons) represents clusters (corresponding to relevant topics) among the retrieved documents, with an output layer representing the relevant documents and their features, and edges representing a relationship between clusters and documents. | 04-01-2010 |
Chengyu Niu, Fishkill, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100073122 | DUAL THIN FILM PRECISION RESISTANCE TRIMMING - A trimmable resistor for use in an integrated circuit is trimmed using a heater. The heater is selectively coupled to a voltage source. The application of voltage to the heater causes the heater temperature to increase and produce heat. The heat permeates through a thermal separator to the trimmable resistor. The resistance of the trimmable resistor is permanently increased or decreased when the temperature of the resistor is increased to a value within a particular range of temperatures. | 03-25-2010 |
Chengyu Niu, Hopewell Junction, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120266452 | DUAL THIN FILM PRECISION RESISTANCE TRIMMING - A trimmable resistor for use in an integrated circuit is trimmed using a heater. The heater is selectively coupled to a voltage source. The application of voltage to the heater causes the heater temperature to increase and produce heat. The heat permeates through a thermal separator to the trimmable resistor. The resistance of the trimmable resistor is permanently increased or decreased when the temperature of the resistor is increased to a value within a particular range of temperatures. | 10-25-2012 |
Chuan S. Niu, Cheshire, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080221181 | COMPOUNDS FOR TREATING TUMORS - The invention provides compounds of formula (I): | 09-11-2008 |
Chuansheng Niu, Cheshire, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090270363 | 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof - The present invention discloses fused bicyclic 2-aryl- or 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumor growth in particular and to treat diseases or disorders associated with securin, including elevated securin levels. | 10-29-2009 |
| 20090270447 | 2-Aryl-and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof - The present invention discloses fused heterobicyclic 2-aryl- and 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumor growth in particular and to treat diseases or disorders associated with securin. | 10-29-2009 |
| 20110028455 | Indole-substituted 3-cyanopyridines As Kinase Inhibitors - Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X is —O—, —N(R | 02-03-2011 |
Chunming Niu, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080224101 | POLYVINYLIDENE FLUORIDE COMPOSITES AND METHODS FOR PREPARING SAME - An electrically conductive composite comprising a polyvinylidene fluoride polymer or copolymer and carbon nanotubes is provided. Preferably, carbon nanotubes may be present in the range of about 0.5-20% by weight of the composite. | 09-18-2008 |
Dequiang Niu, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100185419 | ALGORITHM FOR DESIGNING IRREVERSIBLE INHIBITORS - The invention is an algorithm and method for designing an inhibitor that covalently binds a target polypeptide. The algorithm and method can be used to rapidly and efficiently convert reversible inhibitors into irreversible inhibitors. | 07-22-2010 |
Dong Niu, West Linn, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20110236594 | In-Situ Deposition of Film Stacks - Methods and hardware for depositing film stacks in a process tool in-situ (i.e., without a vacuum break or air exposure) are described. In one example, a method for depositing, on a substrate, a film stack including films of different compositions in-situ in a process station using a plasma is described, the method including, in a first plasma-activated film deposition phase, depositing a first layer of film having a first film composition on the substrate; in a second plasma-activated deposition phase, depositing a second layer of film having a second film composition on the first layer of film; and sustaining the plasma while transitioning a composition of the plasma from the first plasma-activated film deposition phase to the second plasma-activated film deposition phase. | 09-29-2011 |
| 20110236600 | Smooth Silicon-Containing Films - Methods and hardware for depositing ultra-smooth silicon-containing films and film stacks are described. In one example, an embodiment of a method for forming a silicon-containing film on a substrate in a plasma-enhanced chemical vapor deposition apparatus is disclosed, the method including supplying a silicon-containing reactant to the plasma-enhanced chemical vapor deposition apparatus; supplying a co-reactant to the plasma-enhanced chemical vapor deposition apparatus; supplying a capacitively-coupled plasma to a process station of the plasma-enhanced chemical vapor deposition apparatus, the plasma including silicon radicals generated from the silicon-containing reactant and co-reactant radicals generated from the co-reactant; and depositing the silicon-containing film on the substrate, the silicon-containing film having a refractive index of between 1.4 and 2.1, the silicon-containing film further having an absolute roughness of less than or equal to 4.5 Å as measured on a silicon substrate. | 09-29-2011 |
Feng Niu, Weston, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20080240116 | Method and Apparatus for Determining the Locating of Nodes in a Wireless Network - A method and apparatus for determining the relative locations of nodes in a wireless network is disclosed. A list of neighboring nodes of a master node of the wireless network is generated and, from this list, a list of independent nodes is generated. An adjacency table for the independent nodes is then generated by examining the neighbors of dependent nodes. Two independent nodes are determined to be adjacent nodes only if they are the only neighboring nodes of a dependent node. Relative locations of nodes in wireless network may be determined from the adjacency table. | 10-02-2008 |
Fenghul Niu, Lawrence, KS US
| Patent application number | Description | Published |
|---|---|---|
| 20120022287 | Spray Process for Selective Oxidation - Oxidation process can include: introducing small droplets of liquid reaction mixture having oxidizable reactant, catalyst, and solvent into a reaction zone containing oxygen and diluent gas; and oxidizing the reactant with the oxygen at a suitable reaction temperature and a suitable reaction pressure to produce an oxidized product. The liquid reaction mixture can have an aromatic feedstock having an oxidizable substituent as the oxidizable reactant. The oxidized product can include an aromatic compound having at least one carboxylic acid. For example, the aromatic feedstock can include a benzene ring having at least one oxidizable alkyl substituent, furan hetero-ring having at least one oxidizable alkyl substituent, a naphthalene poly-ring having at least one oxidizable alkyl substituent, derivatives thereof, and mixtures thereof. | 01-26-2012 |
Huifeng Niu, Scotch Plains, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080207563 | METHOD FOR INHIBITING PROLIFERATION OF TUMOR CELLS - Disclosed are methods for synergistically inhibiting the proliferation of tumor cells by contacting the tumor cells with a MEK inhibitor compound and erlotinib, either sequentially or simultaneously. Also disclosed are methods for inhibiting the proliferation of tumor cells in a human, by administering to the human, sequentially or simultaneously, an amount of erlotinib and a MEK inhibitor compound, wherein the amounts are effective, in combination, to synergistically inhibit the proliferation of the tumor cells in the human. | 08-28-2008 |
Jianli Niu, Orlando, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20100041736 | Isolated MCPIP and Methods of Use - A monocyte chemoattractant protein (MCP-1)-inducible protein, MCPIP, its polynucleotide and amino acid sequences from mouse and human, and methods for its use are disclosed. | 02-18-2010 |
| 20110002981 | MCPIP Protection Against Cardiac Dysfunction - Disclosed herein are methods and compositions of treating a patient at risk of experiencing sepsis induced cardiac dysfunction. In exemplary examples, the method involves elevating MCPIP levels in a patient in need. Elevating MCPIP levels may involve direct administration (e.g. delivery of protein) or indirect administration (e.g. delivery vehicle capable of increasing expression of MCPIP). | 01-06-2011 |
Joseph H.y. Niu, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080200353 | Viscoelastic surfactant fluids and related methods of use - Viscoelastic surfactant based aqueous fluid systems useful as thickening agents in various applications, e.g. to suspend particles produced during the excavation of geologic formations. The surfactants are zwitterionic/amphoteric surfactants such as dihydroxyl alkyl glycinate, alkyl ampho acetate or propionate, alkyl betaine, alkyl amidopropyl betaine and alkylimino mono- or di-propionates derived from certain waxes, fats and oils. The thickening agent is used in conjunction with an inorganic water-soluble salt or organic additive such as phthalic acid, salicylic acid or their salts. | 08-21-2008 |
| 20110092398 | VISCOELASTIC SURFACTANT FLUIDS AND RELATED METHODS OF USE - Viscoelastic surfactant based aqueous fluid systems useful as thickening agents in various applications, e.g. to suspend particles produced during the excavation of geologic formations. The surfactants are zwitterionic/amphoteric surfactants such as dihydroxyl alkyl glycinate, alkyl ampho acetate or propionate, alkyl betaine, alkyl amidopropyl betaine and alkylimino mono- or di-propionates derived from certain waxes, fats and oils. The thickening agent is used in conjunction with an inorganic water-soluble salt or organic additive such as phthalic acid, salicylic acid or their salts. | 04-21-2011 |
Li Niu, Loudonville, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100099749 | Nucleic Acid Inhibitors Of Glutamate Receptors - The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors. | 04-22-2010 |
| 20120088818 | CONFORMATION-SELECTIVE NUCLEIC ACID INHIBITORS OF AMPA GLUTAMATE RECEPTORS - The present invention relates to novel nucleic acid ligands or aptamers that demonstrate potent and selective inhibition of the open-channel conformation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. | 04-12-2012 |
Li Niu, Loundonville, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120225929 | Nucleic Acid Inhibitors Of Glutamate Receptors - The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors. | 09-06-2012 |
Ling Niu, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090213206 | Aggregation of Video Receiving Capabilities - Video receiving capabilities of participants and source capabilities are compared and conference capabilities for providing different resolutions, frame rates, bit rate, and number of streams are determined by maintaining a conference receiving capability list updated as number and capability of participants' changes. Preferred receiving capabilities of participants are also taken into account in determining conference characteristics based on comparison with allowed capabilities. | 08-27-2009 |
| 20090231415 | Multiple Video Stream Capability Negotiation - Video send and receive capabilities of participants are determined by the respective machines determining available combinations, as well as preferences for the receivers. Receiver capabilities are forwarded to the source for computation of negotiated video capabilities through a logic intersection of the determined capabilities based on desired number of streams and resolutions. If a resolution of a send capability exists within the receive capability, the highest frame and/or bit rate may be selected for transmission. | 09-17-2009 |
| 20120154516 | AGGREGATION OF VIDEO RECEIVING CAPABILITIES - Video receiving capabilities of participants and source capabilities are compared and conference capabilities for providing different resolutions, frame rates, bit rate, and number of streams are determined by maintaining a conference receiving capability list updated as number and capability of participants' changes. Preferred receiving capabilities of participants are also taken into account in determining conference characteristics based on comparison with allowed capabilities. | 06-21-2012 |
| 20120176469 | MULTIPLE VIDEO STREAM CAPABILITY NEGOTIATION - Video send and receive capabilities of participants are determined by the respective machines determining available combinations, as well as preferences for the receivers. Receiver capabilities are forwarded to the source for computation of negotiated video capabilities through a logic intersection of the determined capabilities based on desired number of streams and resolutions. If a resolution of a send capability exists within the receive capability, the highest frame and/or bit rate may be selected for transmission. | 07-12-2012 |
Mei Niu, Tampa, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20110020863 | BIOREACTOR ASSEMBLY AND ASSOCIATED METHODS - A bioreactor assembly, including: a housing internally defining a plurality of reaction chambers; a medium flow supply line associated with each of the plurality of reaction chambers, wherein the medium flow supply line associated with each of the plurality of reaction chambers is operable for delivering a medium flow to each of the plurality of reaction chambers; and one or more framed membrane cartridges selectively disposed within each of the plurality of reaction chambers, wherein each of the one or more framed membrane cartridges disposed within each of the plurality of reaction chambers is operable for holding a biochemically active material that is reacted when exposed to the medium flow. | 01-27-2011 |
Qiang Niu, Novi, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120249128 | MAGNETIC SENSOR SYSTEM - A linear sensor system includes a first field sensor displaced linearly from a second field sensor. A member having high magnetic permeability is disposed between the first field sensor and the second field sensor. The member is optimized in shape and material to completely remove any redirection or interference of the magnetic flux in the field sensors. A torque transmitting device incorporating the linear sensor system is also disclosed. | 10-04-2012 |
| 20120286613 | ASYMMETRIC STATOR TEETH IN AN ELECTRIC MOTOR - A permanent magnet motor includes a permanent magnet rotor, a stator surrounding the rotor having a plurality of teeth radially inwardly oriented toward a longitudinal axis of the stator wherein each tooth has a tooth length and a tooth tip surface geometry. An asymmetric air gap is defined by variations in the tooth lengths and tooth tip surface geometries. | 11-15-2012 |
| 20120293105 | ROTOR SLOT ASYMMETRY IN AN ELECTRIC MOTOR - An electric motor includes a stator configured to receive electrical energy and generate an electromagnetic field in accordance with the electrical energy received. A rotor is in electromagnetic communication with the stator and is configured to rotate in accordance with the electromagnetic field generated by the stator. The rotor includes a plurality of poles including a first set of poles and a second set of poles. The first set of poles defines a first slot and the second set of poles defines a second slot that has a different configuration than the first slot to reduce a torque ripple effect. The electric motor may be used in a system having a power source configured to output direct current energy and an inverter configured to convert direct current energy to alternating current energy. | 11-22-2012 |
Qi-Wen Niu, Staten Island, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100169997 | PROMOTION OF SOMATIC EMBRYOGENESIS IN PLANTS BY WUSCHEL GENE EXPRESSION - The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants. | 07-01-2010 |
| 20110078823 | PROMOTION OF SOMATIC EMBRYOGENESIS IN PLANTS BY WUSCHEL GENE EXPRESSION - The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants. | 03-31-2011 |
| 20110252506 | PROMOTION OF SOMATIC EMBRYOGENESIS IN PLANTS BY WUSCHEL GENE EXPRESSION - The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants. | 10-13-2011 |
| 20120102594 | PROMOTION OF SOMATIC EMBRYOGENESIS IN PLANTS BY WUSCHEL GENE EXPRESSION - The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants. | 04-26-2012 |
Qi-Wen Niu, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080313773 | PRODUCTION OF ARTIFICIAL MICRORNAS USING SYNTHETIC MICRORNA PRECURSORS - The invention provides methods and compositions useful in target sequence suppression, target sequence validation and target sequence down regulation. The invention provides polynucleotide constructs useful for producing artificial microRNA (amiRNA) using synthetic amiRNA precursors. | 12-18-2008 |
Sanjun Niu, Lincoln, NE US
| Patent application number | Description | Published |
|---|---|---|
| 20100237325 | Highly resolved, low noise, room-temperature coulomb-staircase and blockade up to 2.2V in isolated 50 micron long one dimensional necklace of 10 NM AU particles - Coulomb blockade in metal nanoparticles isolated by a tunneling barrier is considered to be a potential solution to low power, robust, high-speed electronic switching device operating at single-electron transport. However, the switching voltage equal to the threshold voltage to overcome coulomb blockade for these devices is typically in the 10 mV range and/or operating at currents well below 1 nA, which inhibits their application as a practical device. Theoretically, a one dimensional nanoparticle necklace is predicted to be an ideal structure to achieve higher switching voltages. The present invention provides a single-electron device composed of a necklace of about 5000 nanoparticles. The linear necklace is self-assembled by interfacial phenomena along a triple-phase line of fiber, a substrate and electrolyte containing nanoparticles. The I-V measurements on the system show both coulomb blockade and staircase, with high currents and high threshold voltage of 1-3 V. The present invention also provides methods for constructing such a device. | 09-23-2010 |
Sanjun Niu, Mundelein, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100120236 | FABRICATION OF ULTRA LONG NECKLACE OF NANOPARTICLES - The present invention provides a single-electron device composed of a necklace of about 5000 nanoparticles. The linear necklace is self-assembled by interfacial phenomena along a triple-phase line of fiber, a substrate and electrolyte containing nanoparticles. A variety of combinations of nanoparticles, such as Au and CdS nanoparticles, may be used to form a necklace. The I-V measurements on the system show both coulomb blockade and staircase, with high currents and high threshold voltage of 1-3 V. The present invention also provides methods for constructing such a device. | 05-13-2010 |
| 20100243984 | Live bioelectronic cell gated nanodevice - This invention is directed toward a bioelectronic cell gated nanodevice. The bioelectronic cell gated nanodevice comprises a plurality of bioelectric cells deposited on a fiber of a nanodevice. The bioelectronic cells of the nanodevice act as a gate, allowing current to be transmitted when the bioelectronic cells are exposed to an actuating chemical. The present invention also provides methods for constructing such a device. | 09-30-2010 |
Sanjun Niu, Lake Villa, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090069743 | INFUSION THERAPY SENSOR SYSTEM - A sensor system for use with an infusion system may include at least one sensor disposed within a catheter, the at least one sensor comprising at least one of an optical sensor, an electrical sensor or a chemical/biochemical sensor. The sensor system may instead include a sample cell that is in fluid communication with the infusion system, which sample cell may be used with an analyzer to determine a patient's condition. The sensor system may be integrated with a control system for an infusion pump to control operation of the pump. | 03-12-2009 |
Suyi Niu, Salt Lake City, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20080228151 | Transdermal drug delivery with controlled heat for treating musculoskeletal pain and/or inflammation - Systems and methods for transdermal drug delivery with controlled heat are provided. Such systems can comprise a heating apparatus that includes an exothermic chemical composition, typically in the form of individual heating elements. The heating apparatus can be exposed to ambient oxygen through a cover. The cover can reduce the amount of ambient oxygen capable of contacting the chemical composition compared to when the cover is not present. In some embodiments, the heating apparatus can include more than one heating element. The systems can further include a drug-containing layer that includes a drug. The drug-containing layer can have a surface area of about 50 cm | 09-18-2008 |
| 20120022158 | SOLID-FORMING LOCAL ANESTHETIC FORMULATIONS FOR PAIN CONTROL - Solid-forming local anesthetic formulations for pain control can include a lidocaine base and tetracaine base, polyvinyl alcohol, water, and an emulsifier. The formulation can be prepared to be in a semi-solid state prior to application to a skin surface, can form a soft solidified layer after application, and can provide pain relief when applied to a skin surface proximate a pain site. | 01-26-2012 |
Tianye Niu, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20120263360 | SCATTER CORRECTION METHODS - Described herein are improved methods for correcting cone beam computed tomography signals to reduce scatter contamination contained therein. Generally, the improved methods involve generating a plurality of two-dimensional projection images of a subject from a three-dimensional multi-detector computed tomography image of the subject. This is followed by subtracting the plurality of two-dimensional projection images from a plurality of two-dimensional cone beam projection images of the subject to produce a plurality of two-dimensional estimated error projections that comprise an estimated error in the plurality of two-dimensional cone beam projection images. The plurality of two-dimensional estimated error projection images are subtracted from the plurality of two-dimensional cone beam projection images to generate a plurality of two-dimensional corrected cone beam projection images. A three-dimensional corrected cone beam computed tomography image of the subject is then constructed from the plurality of two-dimensional corrected cone beam projection images. | 10-18-2012 |
Wei Niu, Wayland, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100099116 | Methods for Analysis of Hedgehog Pathway Inhibitors - One aspect of the present invention relates to a method of ascertaining the inhibitory activity in a mammal of a candidate inhibitor of the hedgehog pathway. In certain embodiments, the candidate inhibitor is administered systemically. In certain embodiments, the mammal is a rodent or primate. In certain embodiments, the mammal is a mouse. In certain embodiments, the candidate inhibitor is a small molecule or natural product. | 04-22-2010 |
Wei Niu, Lincoln, NE US
| Patent application number | Description | Published |
|---|---|---|
| 20110045575 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS - The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO. | 02-24-2011 |
| 20110129899 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO - The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO), 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway comprising at least one exogenous nucleic acid encoding a BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway enzyme expressed in a sufficient amount to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine. | 06-02-2011 |
| 20110217742 | MICROORGANISMS AND METHODS FOR THE COPRODUCTION 1,4-BUTANEDIOL AND GAMMA-BUTYROLACTONE - The invention provides non-naturally occurring microbial organisms comprising 1,4-butanediol (14-BDO) and gamma-butyrolactone (GBL) pathways comprising at least one exogenous nucleic acid encoding a 14-BDO and GBL pathway enzyme expressed in a sufficient amount to produce 14-BDO and GBL. The invention additionally provides methods of using such microbial organisms to produce 14-BDO and GBL. | 09-08-2011 |
| 20110229946 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO - The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO), 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway comprising at least one exogenous nucleic acid encoding a BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway enzyme expressed in a sufficient amount to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine. | 09-22-2011 |
| 20120225463 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS - The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO. | 09-06-2012 |
Weijun Niu, Painted Post, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100305288 | Fused Thiophenes, Articles, and Methods Thereof - Fused thiophene (FT) compounds, FT polymers, FT containing articles, and methods for making and using the FT compounds and polymers thereof of the formulas, as defined herein. | 12-02-2010 |
| 20110166307 | FUSED THIOPHENES, ARTICLES, AND METHODS THEREOF - Fused thiophene (FT) compounds, FT polymers, FT containing articles, and methods for making and using the FT compounds and polymers thereof of the formulas, as defined herein. | 07-07-2011 |
| 20110288306 | METHODS OF MAKING FUSED THIOPHENES - β″-di-R-substituted fused thiophene (DCXFT4) compounds, and a method for making a compound of the formula (V): | 11-24-2011 |
| 20110291054 | POLYMERIC FUSED THIOPHENE SEMICONDUCTOR FORMULATION - A formulation including: | 12-01-2011 |
| 20120022116 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX - Disclosed are compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically related to GPR35, and/or GPR35-hERG signaling complex. For example, disclosed are compounds for preventing and/or treating diseases which are pathophysiologically related to GPR35 in a subject. The compounds having a formula (I), (II) or (III): | 01-26-2012 |
| 20120035375 | DI-TIN FUSED THIOPHENE COMPOUNDS AND POLYMERS AND METHODS OF MAKING - Di-tin fused thiophene (FT) compounds, FT polymers, such as of the formula -{-(FTx)-(Ar) | 02-09-2012 |
| 20120220748 | FIVE-RING FUSED HETEROAROMATIC COMPOUNDS AND CONJUGATED POLYMERS THEREOF - Compounds having a core comprised of an aromatic ring and at least two annulated beta-substituted fused thiophene ring systems of the general formula: | 08-30-2012 |
| 20120295965 | FUSED THIOPHENES AS DUAL INHIBITORS OF EGFR/VEGFR AND THEIR USE IN THE TREATMENT OF CANCER - Disclosed are compositions and methods related to identification of modulators of EGFR and VEGFR. | 11-22-2012 |
| 20120329865 | MOLECULES RELATED hERG ION CHANNELS AND THE USE THEREOF - Disclosed are compounds having structural formula (I, II) or a pharmaceutically acceptable sale, solvate, clathrate, or prodrug thereof, wherein R | 12-27-2012 |
Xiang Niu, Watertown, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110046398 | INTERMEDIATES IN THE SYNTHESIS ZEARALENONE MACROLIDE ANALOGS - Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV), wherein R | 02-24-2011 |
| 20110060151 | REAGENTS AND METHODS FOR THE BETA-KETO AMIDE SYNTHESIS OF A SYNTHETIC PRECURSOR TO IMMUNOLOGICAL ADJUVANT E6020 - This invention relates to the synthesis for a precursor of E6020, compound 26, via a β-keto amide alcohol intermediate, compound 22. The synthesis reacts compound 22 with compound 25 and the resultant intermediate is oxidized to produce compound 26, the precursor to E6020. Compounds 22 and 25, and their crystalline forms, represent separate embodiments of the invention. The invention also relates to compounds of formulas (3) and (4) and processes for their preparation. | 03-10-2011 |
| 20110237805 | INTERMEDIATES AND METHODS FOR MAKING ZEARALENONE MACROLIDE ANALOGS - Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R | 09-29-2011 |
Xiang Niu, Malden, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090187038 | REAGENTS AND METHODS FOR THE BETA-KETO AMIDE SYNTHESIS OF A SYNTHETIC PRECURSOR TO IMMUNOLOGICAL ADJUVANT E6020 - This invention relates to the synthesis for a precursor of E6020, compound 26, via a β-keto amide alcohol intermediate, compound 22. The synthesis reacts compound 22 with compound 25 and the resultant intermediate is oxidized to produce compound 26, the precursor to E6020. Compounds 22 and 25, and their crystalline forms, represent separate embodiments of the invention. The invention also relates to compounds of formulas (3) and (4) and processes for their preparation. | 07-23-2009 |
| 20120232298 | COMPOUNDS FOR PREPARING IMMUNOLOGICAL ADJUVANT - The present invention provides methods for preparing TLR-4 receptor agonist E6020: | 09-13-2012 |
Yanhui Niu, Newark, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20080242831 | Lower-color polytrimethylene ether glycol using zero-valent metals - The present invention relates to a process for preparing lower-color polytrimethylene ether glycol polymer, comprising contacting said polytrimethylene ether glycol polymer, or its precursor reaction-mixture, with a zero-valent metal during at least one stage of the process of manufacture, or on the polytrimethylene glycol resulting form such process, such that the polytrimethylene ether glycol polymer demonstrates a reduced color (as compared to using no zero-valent metal). | 10-02-2008 |
| 20100204376 | Rheology Control Agents - The present invention provides for a rheology control agent that includes a following compound represented by the following formula: | 08-12-2010 |
| 20100204436 | PROCESS FOR PREPARING POLY(TRIMETHYLENE ETHER) GLYCOL AND COPOLYMERS THEREOF - Processes for preparing relatively high molecular weight poly(trimethylene ether)glycol employing a cocatalyst system are provided. | 08-12-2010 |
| 20100204439 | PROCESSES FOR MAKING POLY(TRIMETHYLENE ETHER) GLYCOL USING ORGANOPHOSPHOROUS COMPOUND - Processes for preparing poly(trimethylene ether)glycol-based polymers using an organophosphorous compound are provided. | 08-12-2010 |
Yuhua Niu, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130009131 | DEVICE INCLUDING QUANTUM DOTS - A device including an emissive material comprising quantum dots is disclosed. In one embodiment, the device includes a first electrode and a second electrode, a layer comprising quantum dots disposed between the first electrode and the second electrodes, and a first interfacial layer disposed at the interface between a surface of the layer comprising quantum dots and a first layer in the device. In certain embodiments, a second interfacial layer is optionally further disposed on the surface of the layer comprising quantum dots opposite to the first interfacial layer. In certain embodiments, a device comprises a light-emitting device. Other light emitting devices and methods are disclosed. | 01-10-2013 |
Yuhua Niu, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100051915 | POLYMER CHARGE TRANSPORT MATERIAL FOR OPTOELECTRONIC DEVICES - Polymers that enable the use of high work-function metals as a cathode in optoelectronic devices and optoelectronic devices incorporating the polymers as an electron transport layer. | 03-04-2010 |
Yu-Hua Niu, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090153021 | LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS - Polymers and compounds having high-triplet-energy; guest-host films comprising the polymers or compounds as hosts and phosphorescent compounds as guests; and electroluminescent devices that include the films. | 06-18-2009 |
| 20090278445 | CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES - Crosslinkable compounds useful for making hole-transporting materials for organic light-emitting devices, hole-transporting layers made from the crosslinkable compounds, and light-emitting devices that include the hole-transporting layers. | 11-12-2009 |
Yuping Niu, River Vale, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080234340 | Synthesis and characterization of polymorph form II of 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-YL)thiazol-4-YL)benzonitrile - A polymorph Form II of 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzonitrile and methods of preparing Form II are described. Also provided are methods of contraception, treating or preventing fibroids, uterine leiomyomata, endometriosis, dysfunctional bleeding, polycystic ovary syndrome, and hormone-dependent carcinomas, providing hormone replacement therapy, stimulating food intake, and synchronizing estrus including using polymorph Form II of 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzonitrile. | 09-25-2008 |
| 20080312306 | POLYMORPHS, SOLVATES, AND HYDRATE OF 5-(4'-FLUORO-2'-OXO-1',2'-DIHYDROSPIRO[CYCLOPROPANE-1,3'-INDOL]-5'-YL)-1-METHYL-1H-PYRROLE-2-CARBONITRILE - Novel polymorph Form II and III, solvate Forms I, II, III, and IV, and the hydrate of 5-(4′-fluoro-2′-oxo-1′,2′-dihydrospiro[cyclopropane-1,3′-indol]-5′-yl)-1-methyl-1H-pyrrole-2-carbonitrile are provided, as are methods for preparing the same. Pharmaceutical compositions and kits containing these novel polymorphs, solvates, and hydrate, and combinations thereof are further provided, as are methods of contraception; treating or preventing fibroids, uterine leiomyomata, endometriosis, dysfunctional bleeding, polycystic ovary syndrome, hormone-dependent carcinomas; treating symptoms of premenstrual syndrome and premenstrual dysphoric disorder; providing hormone replacement therapy; stimulating food intake; synchronizing estrus; or treating symptoms of premenstrual syndrome using one or more of these polymorphs, solvates, or hydrate. | 12-18-2008 |
| 20110281900 | Crystalline Pharmaceutical - New crystalline forms of lopinavir are disclosed. | 11-17-2011 |