Patent application number | Description | Published |
20080318277 | Expression of human milk proteins in transgenic plants - The invention is directed to seed and seed extract compositions containing levels of a human milk protein between 3-40% or higher of the total protein weight of the soluble protein extractable from the seed. Also disclosed is a method of producing the seed with high levels of extractable human milk protein. The method includes transforming a monocotyledonous plant with a chimeric gene having a protein-coding sequence encoding a protein normally present in human milk under the control of a seed maturation-specific promoter. The method may further includes a leader DNA sequence encoding a monocot seed-specific transit sequence capable to target a linked milk protein to a storage body. | 12-25-2008 |
20090156486 | PRODUCTION OF HUMAN DEFENSINS IN PLANT CELLS - The present invention relates, generally, to the production of human defensins from plant cells. Heterologous DNA comprising genes encoding one or more desired human defensins are introduced into plant cells. The one or more human defensins can be recombinantly-produced in the plant cells, purified from the plant cells, and used as an anti-infective agent, a wound treatment agent, a skin care agent, or an agent in the treatment of various intestinal diseases, including irritable bowel disease (IBD), ulcerative colitis, and Crohn's disease. The recombinantly-produced α-defensins can be provided as oral and topical formulations. | 06-18-2009 |
20090258004 | HUMAN BLOOD PROTEINS EXPRESSED IN MONOCOT SEEDS - The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, and to methods of making these isolated blood proteins and to therapeutic compositions comprising them. | 10-15-2009 |
20100003235 | ORAL FORMULATIONS FOR ENTERIC DISORDERS AND/OR REHYDRATION - The present invention relates, generally, to oral formulations including one or more recombinantly-produced human milk proteins. The formulations of the present invention may be used to prevent the onset of diarrhea in patients who have been or will be exposed to one or more agents known to cause diarrhea, and to prevent the recurrence of diarrhea in a patient recovering therefrom. The formulations may also be used in the treatment of inflammatory bowel disease, including Crohn's disease and ulcerative colitis. The formulations may also be beneficially administered in accordance with methods for promoting the development of healthy intestinal flora in a human patient. | 01-07-2010 |
20100015713 | COMPONENTS OF CELL CULTURE MEDIA PRODUCED FROM PLANT CELLS - The present invention comprises the production of components of cell culture media produced from plant cells and cell culture media containing the same. Heterologous DNA comprising genes encoding the desired component are introduced into plant cells, especially rice, which then produce the desired component. The component can be isolated from the plant cell and combined with other components to form the required cell culture medium. | 01-21-2010 |
20100031394 | Human Blood Proteins Expressed in Monocot Seeds - The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, and to methods of making these isolated blood proteins and to therapeutic compositions comprising them. | 02-04-2010 |
20100119691 | EXPRESSION OF HUMAN MILK PROTEINS IN TRANSGENIC PLANTS - The invention is directed to food and food additive compositions comprising one or more human milk proteins produced in the seeds of a transgenic plant and methods of making the same. The invention is further directed to improved infant formula comprising such food supplement composition. | 05-13-2010 |
20100183589 | HUMAN BLOOD PROTEINS EXPRESSED IN MONOCOT SEEDS - The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, and to methods of making these isolated blood proteins and to therapeutic compositions comprising them. | 07-22-2010 |
20110117131 | Production of OspA for Lyme Disease Control - The present invention relates, generally, to the production of one or more OspA proteins in plant cells. Heterologous DNA comprising genes encoding one or more desired OspA protein(s) are introduced into plant cells. The one or more OspA protein(s) can be recombinantly-produced in the plant cells, optionally purified from the plant cells, and used as an oral vaccine to prevent the transmission of Lyme disease, particularly by animal vectors. The recombinantly-produced OspA protein(s) can be provided in oral and parenteral formulations. The present invention also relates to oral administration of OspA protein(s) to vaccinate against Lyme disease. The OspA protein(s) may be provided in a dosage form that is suitable for oral administration as a vaccine to prevent an animal from developing Lyme disease after exposure to a source of | 05-19-2011 |
20120088729 | NON-GLYCOSYLATED TRANSFERRIN EXPRESSED IN MONOCOTS - Disclosed are compositions and methods of making non-glycosylated transferrin protein in transgenic monocot plants. | 04-12-2012 |
20120195883 | MONOCOT SEED PRODUCT COMPRISING A HUMAN BLOOD PROTEIN - The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, as well as to methods of making these isolated blood proteins and to therapeutic compositions comprising them. | 08-02-2012 |
20120315697 | Cell Culture Media Containing Combinations of Proteins - The present invention relates to cell culture media containing combinations of proteins, as well as methods of making the cell culture media, and methods of using the cell culture media to improve growth characteristics of cultured cells. | 12-13-2012 |