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Niklason, NC

Laura Niklason, Hillsborough, NC US

Patent application numberDescriptionPublished
20080248080Decelluarlized Tissue Engineered Constructs and Tissues - New methods for producing tissue engineered constructs and engineered native tissues are disclosed. The methods include producing a tissue engineered construct by growing cells in vitro on a substrate and then decellularizing the construct to produce a decellularized construct consisting largely of extracellular matrix components. The construct can be used immediately or stored until needed. The decellularized construct can be used for further tissue engineering, which may include seeding the construct with cells obtained from the intended recipient of the construct. During any of the growth phases required for production of the construct, the developing construct may be subjected to various tissue engineering steps such as application of mechanical stimuli including pulsatile forces. The methods also include producing an engineered native tissue by harvesting tissue from an animal or human, performing one or more tissue engineering steps on the tissue, and subjecting the tissue to decellularization. The decellularized, engineered native tissue may then be subjected to further tissue engineering steps.10-09-2008

Loren Niklason, Hillsborough, NC US

Patent application numberDescriptionPublished
20090080752Breast tomosynthesis with display of highlighted suspected calcifications - Systems and methods that facilitate the presentation and assessment of selected features in projection and/or reconstructed breast images, such as calcifications that meet selected criteria of size, shape, presence in selected slice images, distribution of pixels that could be indicative of calcification relative to other pixels or of other image features of clinical interest.03-26-2009
20090135997Breast Compression For Digital Mammography, Tomosynthesis And Other Modalities - A breast x-ray imaging method and system that is particularly suited for tomosynthesis imaging but also is useful for conventional mammography. A fluid containing pillow or bag is placed between the breast and a paddle that compresses the breast against a breast platform covering an imaging device, to enhance patient comfort and provide other benefits. Alternatives include a flexible sheet compressing the breast, and a compressible foam, preferably contoured to accommodate a patient's breast.05-28-2009
20090141859Image Handling and Display in X-Ray Mammography and Tomosynthesis - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images06-04-2009
20090213987System and Method for Low Dose Tomosynthesis - A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.08-27-2009
20090296882Image Handling And Display In X-Ray Mammography And Tomosynthess - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images12-03-2009
20090304147X-RAY MAMMOGRAPHY/TOMOSYNTHESIS OF PATIENT'S BREAST - A breast x-ray system and method using tomosynthesis imaging in which the x-ray source generally moves away from the patient's head. The system may include an operation mode in which it additionally takes mammogram image data.12-10-2009
20100086188Breast Tomosynthesis With Display Of Highlighted Suspected Calcifications - Systems and methods that facilitate the presentation and assessment of selected features in projection and/or reconstructed breast images, such as calcifications that meet selected criteria of size, shape, presence in selected slice images, distribution of pixels that could be indicative of calcification relative to other pixels or of other image features of clinical interest.04-08-2010
20110135185IMAGE HANDLING AND DISPLAY IN X-RAY MAMMOGRAPHY AND TOMOSYNTHESIS - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images06-09-2011

Patent applications by Loren Niklason, Hillsborough, NC US