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Niklason
Laura Niklason, Greenwich, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090028817 | Compositions and methods for soft tissue augmentation - The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 01-29-2009 |
| 20090108503 | Method and System for Aligning Fibers During Electrospinning - A method and system are provided for aligning fibers in an electrospinning process. A jet of a fiberizable material is directed towards an uncharged collector from a dispensing location that is spaced apart from the collector. While the fiberizable material is directed towards the collector, an elliptical electric field is generated via the electrically charged dispenser and an oppositely-charged control location. The field spans between the dispensing location and the control location that is within line-of-sight of the dispensing location, and impinges upon at least a portion of the collector. Various combinations of numbers and geometries of dispensers, collectors, and electrodes can be used. | 04-30-2009 |
Laura A. Niklason, Greenwich, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120028234 | TISSUE AND ORGAN GRAFT BIOREACTOR AND METHOD OF OPERATION - A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions. | 02-02-2012 |
Laura E. Niklason, Greenwich, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090319033 | METHOD FOR ENDOTHELIAL CELL EXTRACTION FROM ADISPOSE TISSUES - Adipose tissue has proven to serve as an abundant, accessible, and rich source of endothelial or vascular endothelial cells suitable for tissue engineering. We describe a detailed method for the isolation and purification of endothelial cells using purified enzymes and antibody-based selection. The cells can be obtained from liposuction procedures and used in vascular grafts. | 12-24-2009 |
| 20110020271 | ELASTIN FOR SOFT TISSUE AUGMENTATION - The present invention provides compositions comprising isolated elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 01-27-2011 |
| 20120064050 | Tissue Engineering of Lung - The present invention relates to compositions comprising a decellularized tissue. The present invention also provides an engineered three dimensional lung tissue exhibiting characteristics of a natural lung tissue. The engineered tissue is useful for the study of lung developmental biology and pathology as well as drug discovery. | 03-15-2012 |
Lennart Niklason, Sollentuna SE
| Patent application number | Description | Published |
|---|---|---|
| 20080220464 | BLOOD TEST INSTRUMENT USING A DISPOSABLE CARTRIDGE - A blood test instrument using a disposable cartridge and a method of measuring a blood sample using the instrument are disclosed. The instrument includes a cell counting station for counting blood cells by electrical resistance measurement, a pressure actuating component adapted to apply a pressure alternately on two flexible receptacles of a disposable cartridge removably placed in the instrument to cause flowing of a mixture of a blood sample and a liquid agent between the two receptacles to obtain proper mixing, and a conduit adapted to deliver the mixture to the cell counting station for counting. After measuring the blood sample, the instrument withdraws a washing liquid contained in another receptacle of the disposable cartridge and uses the washing liquid to clean the instrument and to deliver the mixture back to the cartridge for disposal. | 09-11-2008 |
| 20100221150 | APPARATUS FOR FILLING A SAMPLE VOLUME DEFINING DEVICE - An apparatus for filling a sample volume defining device for separating at least one small defined volume of a liquid sample from a relatively larger undefined volume of said sample, said device including a first body and a second body movable relative to each other, whereby said first body has at least one cavity in a surface thereof, said at least one cavity having said defined volume. One of said first or said second body has at least one inlet opening adapted to be placed in a drop of the liquid sample. A defined channel is provided between said first and second body, which channel has fluid connection with said at least one opening and at least beyond said at least one cavity whereby the dimensions of said channel being such that said channel and said at least one cavity is filled with said liquid sample. | 09-02-2010 |
| 20110039298 | METHOD OF MEASURING BLOOD SAMPLE ON BLOOD TEST INSTRUMENT USING A DISPOSABLE CARTRIDGE - A blood test instrument using a disposable cartridge and a method of measuring a blood sample using the instrument are disclosed. The instrument includes a cell counting station for counting blood cells by electrical resistance measurement, a pressure actuating component adapted to apply a pressure alternately on two flexible receptacles of a disposable cartridge removably placed in the instrument to cause flowing of a mixture of a blood sample and a liquid agent between the two receptacles to obtain proper mixing, and a conduit adapted to deliver the mixture to the cell counting station for counting. After measuring the blood sample, the instrument withdraws a washing liquid contained in another receptacle of the disposable cartridge and uses the washing liquid to clean the instrument and to deliver the mixture back to the cartridge for disposal. | 02-17-2011 |
Loren Niklason, Tetonia, ID US
| Patent application number | Description | Published |
|---|---|---|
| 20120033868 | DETECTING AND QUANTIFYING PATIENT MOTION DURING TOMOSYNTHESIS SCANS - The effects of patient motion in tomosynthesis scan images are automatically detected and quantified. In at least one embodiment an indication of detection of the effects of patient motion in tomosynthesis scan images is provided shortly after the scan, e.g., before the patient is discharged or before the breast is decompressed. A patient motion score may be calculated as part of motion quantification. The score may be stored for subsequent retrieval. Images may be presented with reference features to help a technician confirm of the effects of motion in images. | 02-09-2012 |
Loren Niklason, N.tetonia, ID US
| Patent application number | Description | Published |
|---|---|---|
| 20120114095 | Upright x-ray breast imaging with a CT mode, multiple tomosynthesis modes, and a mammography mode - A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast. | 05-10-2012 |