Nieman, US
David Nieman, Weaverville, NC US
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20140050800 | METHOD OF REDUCING OXIDATIVE STRESS - Methods of ameliorating cellular oxidative stress and reducing serum cholesterol are disclosed. | 02-20-2014 |
20140056991 | METHOD OF MODULATING FATTY ACID MOBILIZATION AND OXIDATION - Methods of mobilizing fatty acids are disclosed. | 02-27-2014 |
Derek E. Nieman, Peoria, IL US
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20150369160 | METHOD OF CONTROLLING INJECTION PRESSURE LEVEL IN UNIT INJECTORS - A method to control an injection pressure level of fuel within a unit injector is provided. The method includes provision of a second spill valve in the unit injector, which is connected in parallel to a first spill valve. The fuel is delivered to the unit injector with the first spill valve maintained in a passive state. This facilitates return of the first portion of the fuel to the low-pressure fuel manifold. The first spill valve is actuated to an active state to block the flow of fuel to the low-pressure fuel manifold, to maintain the unit injector at the injection pressure level. The second spill valve is actuated concurrently or prior to the actuation of the first spill valve. This facilitates return of a second portion of the fuel to the low-pressure fuel manifold. This is done to limit the injection pressure level within the unit injector. | 12-24-2015 |
Gary F. Nieman, Manlius, NJ US
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20140088567 | Compositions and Methods for Removing Ascitic Fluid from the Abdomen - The present invention features devices that can be used to extract ascites and other fluids from the body with a minimally invasive procedure and, if desired, can also be used to flush the cavity (e.g., the abdominal cavity) from which the fluids were removed. The devices also permit characterization of the fluids in that a surgeon or other health care provider can conveniently obtain a sample of the fluids to assess their composition. The amount of fluid removed from a cavity can also be determined. While the present devices and procedures are not limited to those that bring about any particular physiological response, we believe they will help maintain blood flow and prevent the accumulation of toxins and inflammatory cytokines in bodily cavities, such as the abdominal cavity. We may refer to the devices of the invention as MIST, as they allow for minimally invasive suction and treatment. | 03-27-2014 |
James Nieman, Kalamazoo, MI US
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20090264487 | HEMIASTERLIN ANALOGS - This invention provides analogs of hemiasterlin, methods of synthesis of the analogs and use of the analogs as a cytotoxic anti-mitotic agents. | 10-22-2009 |
Karl F. Nieman, Austin, TX US
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20150326286 | Massive MIMO Architecture - Techniques are disclosed relating to a massive MIMO base station architecture. In some embodiments, a base station is configured to combine signals received by multiple antennas and, for at least a subset of processing elements included in the base station, each processing element is configured to operate on a different portion of the combined signals. In these embodiments, each portion includes signals from multiple antennas. In some embodiments, the portions are different time and/or frequency portions of the combined signals. In some embodiments, this distributed processing may allow the number of antennas of the base station to scale dramatically, provide dynamic re-configurability, facilitate real-time reciprocity-based precoding, etc. | 11-12-2015 |
20150326291 | Signaling and Frame Structure for Massive MIMO Cellular Telecommunication Systems - Techniques are disclosed relating to signaling and frame structure for massive MIMO communication systems. In some embodiments, an apparatus is configured to receive an uplink pilot symbol from a mobile device over a first channel and receive uplink data from the mobile device over the first channel, where the uplink data is included in one or more orthogonal frequency division multiplexing (OFDM) symbols at a symbol rate. In these embodiments, the apparatus is configured to, determine channel information based on the pilot symbol, precode downlink data based on the channel information, and transmit the precoded downlink data to the mobile device. In these embodiments, a transition interval between receiving the uplink pilot symbol and beginning to transmit the precoded downlink data corresponds to less than five OFDM symbols at the symbol rate. This may facilitate reciprocity-based precoding for fast-moving mobile devices, in some embodiments. | 11-12-2015 |
20150326383 | Synchronization of Large Antenna Count Systems - Techniques are disclosed relating to synchronization of radios in a large antenna count (LAC) system. In some embodiments, a LAC system includes a plurality of slave radios, a clock and trigger distribution system, and a master device. In these embodiments, the plurality of slave radios are configured to establish a fixed relationship between a reference clock and their respective local clocks. In these embodiments, the master device and plurality of slave radios are configured to generate and align respective common periodic time reference (CPTR) signals, at a lower frequency than the local clocks. In these embodiments, the master device is configured to transmit a trigger signal based on its CPTR and the plurality of slave radios are configured to perform an action based on the trigger at a subsequent edge of their CPTRs. This may allow synchronization of sampling for antennas in a massive MIMO base station, for example. In some embodiments the master device a radio and includes a local clock, is configured to establish and maintain a fixed relationship between a reference clock and its local clock, and is configured to perform an action based on the trigger at the subsequent edge of its CPTR. | 11-12-2015 |
Kevin Nieman, Avon, OH US
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20130106416 | ROUTER AND COIL ARRAY FOR ULTRA HIGH FIELD MRI | 05-02-2013 |
Kevin M. Nieman, Avon, OH US
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20080312526 | HYBRID PET/MR IMAGING SYSTEMS - A hybrid imaging system includes a magnetic resonance scanner and a second modality imaging system disposed in the same radio frequency isolation space. The second modality imaging system includes radiation detectors configured to detect at least one of high energy particles and high energy photons. In some embodiments a retractable radio frequency screen is selectively extendible into a gap between the magnetic resonance scanner and the second modality imaging system. In some embodiments shim coils are disposed with the magnetic resonance scanner and are configured to compensate for distortion of the static magnetic field of the magnetic resonance scanner produced by proximity of the second modality imaging system. | 12-18-2008 |
20110115483 | TRANSMIT/RECEIVE COIL FOR ULTRA-HIGH FIELD MRI - A magnetic resonance coil comprises a first set of coil elements ( | 05-19-2011 |
Kristin Nieman, Mitchelville, IA US
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20160074459 | PLANT EXTRACTS FOR IMPROVING COGNITIVE FUNCTION - Extracts of plants of the Lamiaceae family, including the | 03-17-2016 |
Kristin Nieman, Westchester, IL US
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20120289570 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING CANCER BY INHIBITING FATTY ACID BINDING PROTEINS - The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins. | 11-15-2012 |
20140363522 | Compositions and Methods for Treating and/or Preventing Cancer by Inhibiting Fatty Acid Binding Proteins - The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins. | 12-11-2014 |
Leonard C. Nieman, Warren, MI US
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20130012179 | ENHANCED SMARTPHONE IN-VEHICLE ACCOMMODATION - A system and method for configuring communications between a wireless device and a vehicle telematics unit over a short-range wireless communication link includes receiving a serial port profile (SPP) software application at a wireless device from a central facility; storing the SPP software application at the wireless device; identifying third-party software applications stored on the wireless device using the SPP software application; sending the identity of the third-party software applications to the central facility; and communicating between the wireless device and a vehicle telematics unit via a short-range wireless communication link using the stored SPP software application and data transmitted using one or more software templates that have been received by the vehicle telematics unit in response to the identity of the third-party software applications sent. | 01-10-2013 |
20140303806 | APPARATUS AND METHODS FOR PROVIDING TAILORED INFORMATION TO VEHICLE USERS BASED ON VEHICLE COMMUNITY INPUT - The present disclosure relates to a method, for providing a relevant information set, based on vehicle crowd data, to vehicles. The method includes receiving, from a plurality of participating vehicles, vehicle crowd data relating to a condition sensed by the participating vehicles in a geographic area, yielding received vehicle crowd data. In one embodiment, the condition includes at least one pre-identified condition selected from a group consisting of cruise-control engagement, road hazard, icy road, other slick-road condition, and vehicle-security violation. The method also includes filtering the received vehicle crowd data, yielding relevant vehicle crowd data, and constructing, by the device, using the relevant vehicle crowd data, the relevant information set. The method further includes sending the relevant information set for delivery to one or more user vehicles associated with the geographic area. | 10-09-2014 |
20150261754 | METHOD AND APPARATUS OF USER RECOMMENDATION SYSTEM FOR IN-VEHICLE APPS - A method and system for recommending applications to users of in-vehicle infotainment systems are disclosed. Application rating data from many road vehicle infotainment system users are collected on a central server, including both explicit ratings and implicit ratings. Implicit ratings may be calculated based on application usage data. The user/application rating data is filtered for relevance, and then analyzed to determine inferred ratings for user/application relationships where no rating exists. The inferred ratings are calculated using both a user-driven consensus rating calculation and an application-driven consensus rating calculation. The inferred ratings, along with optional cyberspace-based external inputs, are used to synthesize application recommendations for users. The synthesized recommendations for application consideration are provided to the appropriate user via downloading from the central server to the infotainment system in the user's vehicle. | 09-17-2015 |
20150262198 | METHOD AND APPARATUS OF TRACKING AND PREDICTING USAGE TREND OF IN-VEHICLE APPS - A method and system for tracking and predicting usage trends for in-vehicle infotainment system applications are disclosed. Application usage data are collected in the infotainment systems of many road vehicles. Vehicle context relevance indicators are also provided, using data from the vehicle CAN bus or other data bus. The context relevance indicators—which indicate vehicle contextual situations such as traffic and weather conditions, presence of back seat passengers, length of driving trip, etc.—are cross-referenced to the application usage data to determine which applications are likely to be used in which situations. Application usage data and application/context correlation data from many vehicles are collected on a central server and analyzed to provide various metrics which are indicative of application usage trends. The application usage trend data can be used by vehicle manufacturers to optimize future infotainment system designs. | 09-17-2015 |
20160025507 | CARPOOL FINDER ASSISTANCE - A method of determining ride share compatibility. Vehicle data acquisition devices are employed to collect user attribute information relating to a travel route and locations traveled by the operator. The attribute information includes regularity data, frequency data, and duration data. A regression analysis is applied by a processor for using the regularity data, the frequency data, and the duration data, for identifying an importance probability of each of the locations visited by the operator. A match is determined between the operator and a potential travel partner traveling to locations in proximity to the locations traveled by the operator. | 01-28-2016 |
Linda T. Nieman US
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20120075619 | FIBER-OPTIC PROBES AND ASSOCIATED METHODS - Fiber-optic probes are provided comprising an illumination fiber and a plurality of collection beveled fibers. In some embodiments, the fiber-optic probes may further comprise a collection flat-tip fiber. A system comprising a fiber-optic probe operably connected to a spectrometer, wherein the fiber-optic probe comprises an illumination fiber and a plurality of collection beveled fibers is provided. Associated methods are also provided. | 03-29-2012 |
Lynnette Nieman, Bethesda, MD US
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20090192130 | Method for Treating Uterine Fibroids - The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids. | 07-30-2009 |
20130023506 | METHOD FOR TREATING UTERINE FIBROIDS - The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids. | 01-24-2013 |
20140187525 | METHOD FOR TREATING UTERINE FIBROIDS - The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids. | 07-03-2014 |
20150174140 | METHOD FOR ON-DEMAND CONTRACEPTION - The invention relates to a method for on-demand contraception, which method comprises administering a progestogen agent or progesterone receptor modulator, such as 17a-acetoxy-11b-(4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal acetate) in a woman, within 72 hours before an intercourse or within 120 hours after the intercourse. | 06-25-2015 |
20160022698 | METHOD FOR TREATING UTERINE FIBROIDS - The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids. | 01-28-2016 |
Robert Paul Nieman, Loudonville, NY US
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20090112912 | Reference Architecture Framework - An architecture record can be created for a computer system that includes a plurality of computing devices, each having an operating system. The architecture record includes platform definition architectures each associated with one of the computing devices and the operating system of the computing device, domain reference architectures each associated with one or more of the platform definition architectures and a service performed by the computing device of each platform definition architecture, and channel reference architectures each associated with one or more of the domain reference architectures, wherein the computing devices associated with the one or more domain reference architectures are configured to communicate with each other while performing the respective services associated with the one or more domain reference architectures. | 04-30-2009 |
Ronald J. Nieman, Colwich, KS US
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20100176243 | Anti-Icing Piccolo Tube Standoff - A standoff structure for an anti-icing piccolo tube wherein a flexible structure is formed from support ribs, a support bar and a diverter bar for supporting the piccolo tube within the slat or other aircraft leading edge, and for diverting hot gas from the piccolo tube across the inner surface of the slat or other aircraft leading edge. | 07-15-2010 |
20140116194 | SELF-CENTERING AIRCRAFT FLAP POSITION COMMAND APPARATUS - An apparatus for controlling positioning of flaps in an aircraft includes a shift lever movable to each of a plurality of shift lever positions to control positioning of the flaps of the aircraft to each of a respective plurality of associated flap positions. A shift lever indexing plate includes a plurality of engagement positions associated with the plurality of shift lever positions, respectively, the shift lever being coupled to an engagement member, the engagement member moving with the shift lever and being biased to selectively engage a selected one of the plurality of the engagement positions associated with a selected one of the shift lever positions to command the aircraft flaps to the flap position associated with the selected one of the shift lever positions. The shift lever indexing plate includes a web portion which separates the engagement positions of the shift lever indexing plate, the web portion and the shift lever being shaped and the shift lever being biased such that when the shift lever is at rest and only the shift lever bias is applied to the shift lever, the engagement member must be engaged with one of the plurality of engagement positions of the shift lever indexing plate. | 05-01-2014 |
Shawn Nieman, Grand Prairie, TX US
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20140020410 | CONTROLLING METERING DEVICES - A metering device may automatically control fluid flow through a valve. A control system may alter the automatic control of a metering device. In some implementations, a predetermined event may occur to alter the automatic control of the metering device. | 01-23-2014 |
Thomas Nieman, Greenfield, WI US
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20090006010 | Method and System for Remote Monitoring and Control of Wireless Cell-Sites - A method and system for remotely monitoring and controlling one or more cell-sites are disclosed. In one embodiment, the method includes (a) receiving data indicative of a status of at least one battery of at least one cell-site at a remote processing device, where the status relates to at least one of a voltage status, a conductance status, and a temperature status. Additionally, the method includes (b) processing the data at the processing device, and (c) determining at least one further action that should be taken by the at least one cell-site in response to the data. Further, the method includes (d) sending from the processing device at least one control signal to the at least one cell-site configured to cause the at least one cell-site to take the at least one further action. Also, in other embodiments, the method involves remote monitoring and controlling of devices other than batteries. | 01-01-2009 |
Thomas A. Nieman, Austin, TX US
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20130041788 | Method and System for Calculating and Reporting Fund Values for Omnibus Investment Accounts - An omnibus fund accounting system is described that comprises a system of servers and databases connected to a network that can host a set of application instructions and a fund investment database to manage multiple fund investments. An institutional investor places an investment with an investment fund. The institutional investment comprises a plurality of individual investors who may invest at varied times and in varied amounts. The discrepancies in investment initiation dates by individual investors causes expenses such as performance based management fees to be assessed differently against each individual investor. The omnibus fund accounting system tracks the increases or decreases in overall fund performance with respect to the institutional investment or, alternatively, with respect to the fund as a whole. This may be reflected by the overall net asset value of the institutional investment or the fund as a whole as determined by the omnibus fund accounting system. The omnibus fund accounting system also accommodates the deviations in costs attributable to each individual investor while tracking the overall institutional investment performance. The omnibus fund accounting system may accommodate deviations in costs for each individual investor with the addition of positive unit adjustments or subtraction of negative unit adjustments to or from individual accounts. The omnibus fund accounting system reports the performance of the individual investments and the overall institutional investment to the institutional investor. | 02-14-2013 |
Tim Nieman, Salt Lake City, UT US
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20090292160 | Electromagnetic Cardiac Assist Device and Method - Embodiments of the present invention provide systems and methods for assisting with contraction of the heart muscle. For example, in one embodiment of the invention, one or more flexible strips are attached to the surface of the heart, each strip having a plurality of electromagnets alternating with a plurality of permanent magnets. The electromagnets are electrically coupled to a control device and a power supply for generating current in the electromagnets. The control device controls the current in the electromagnets in such a way that the electromagnets are periodically activated to attract the adjacent permanent magnets to assist with contraction of the heart muscle. In some embodiments a sensor is provided for sensing the sinus rhythm so that the control device can activate the electromagnets based on the sensed sinus rhythm. | 11-26-2009 |
20140048067 | ELECTROLYSIS SYSTEM AND APPARATUS FOR COLLECTING HYDROGEN GAS - The present disclosure relates to an electrolysis apparatus that includes an anode electrically connectable to a direct current electrical source. The apparatus also includes a cathode comprising a proximal segment and a distal segment. The proximal segment is electrically connectable to the direct current electrical source. Further, the apparatus includes a hydrogen collector receptacle that limits generation and collection of hydrogen at the cathode to a specified amount. The hydrogen collector receptacle encompasses a portion of the cathode. Also, the apparatus includes a delivery device that receives hydrogen from and is connected to the hydrogen collector receptacle. According to one embodiment, the hydrogen gas generated in the electrolysis apparatus and collected in the collector receptacle is less than about 4.5% of a user's breath. | 02-20-2014 |
Tim Nieman, North Salt Lake, UT US
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20100305503 | OPTICALLY GUIDED FEEDING TUBE, CATHETERS AND ASSOCIATED METHODS - The present invention provides devices and methods for safe, easy and cost effective means of placing and verifying proper placement of nasogastric and nasoenteric feeding tubes. Specifically, an integrated feeding device including a tube operable to deliver a nutritional and/or medicinal substance to the gastrointestinal tract, an optical system including a light source, flexible optical fibers or a camera, and a lens, and a steering system is disclosed. The components of the system, namely the optical system and the steering system, may be integrated into the tube. | 12-02-2010 |
20140039253 | Optically Guided Feeding Tube, Catheters and Associated Methods - The present invention provides devices and methods for safe, easy and cost effective means of placing and verifying proper placement of nasogastric and nasoenteric feeding tubes. Specifically, an integrated feeding device including a tube operable to deliver a nutritional and/or medicinal substance to the gastrointestinal tract, an optical system including a light source, flexible optical fibers or a camera, and a lens, and a steering system is disclosed. The components of the system, namely the optical system and the steering system, may be integrated into the tube. | 02-06-2014 |
20150151098 | SKIN PUNCTURING DEVICE - A safety needle assembly for skin puncturing. A plurality of needles driven by a reciprocating drive shaft extend and retract through an opening in one end of the assembly. Eleven or twelve needles are configured so as to minimize potential surface tension and reduce stress applied to the skin. The opening may be rounded or scalloped to reduce friction on the skin. An elastomeric or mechanical spring is used to assist in retracting the needles. Various alignment tabs and features are used to ensure proper alignment of the drive shaft within the assembly, and alignment of the needle assembly when attached to a handpiece during use. Safety tabs on the needle assembly prevent reuse. A protective sleeve may be used to cover the exterior of the needle assembly. | 06-04-2015 |
Timothy Nieman, North Salt Lake, UT US
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20140249540 | DEVICE OF INSERTING AND CONTROLLING A SNARE - Embodiments of the present invention relate to systems, methods, and apparatus for introducing and/or controlling a snare in a lumen (e.g., a lumen of a catheter tube, a body lumen, etc.). In one example, a snare loading device can reduce the size of a loop on a snare to allow the snare to be inserted into the catheter tube. Furthermore, before and/or after insertion of the snare into the catheter tube, the snare loading device can control the snare, by transferring motion thereto. | 09-04-2014 |
Timothy R. Nieman, Salt Lake City, UT US
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20120116160 | OPTICALLY GUIDED MEDICAL TUBE AND CONTROL UNIT ASSEMBLY AND METHODS OF USE - An optical medical tube and control unit assembly and methods of using the same are provided. The optical medical tube may include a steering mechanism and an imaging device which provides the user a visual aid when placing a tube in the body of a patient. The optical medical tube may be coupled to a coupling adaptor to enable quick and easy connecting of the imaging device and steering mechanism of the tube with a control unit such that a single control unit may be used to place multiple feeding tubes or confirm that a feeding tube remains in its proper position without the need for lengthy sterilization procedures between uses. | 05-10-2012 |
20120116161 | OPTICALLY GUIDED MEDICAL TUBE AND CONTROL UNIT ASSEMBLY AND METHODS OF USE - An optical medical tube and control unit assembly and methods of using the same are provided. The optical medical tube may include a steering mechanism and an imaging device which provides the user a visual aid when placing a tube in the body of a patient. The optical medical tube may be coupled to a coupling adaptor to enable quick and easy connecting of the imaging device and steering mechanism of the tube with a control unit such that a single control unit may be used to place multiple feeding tubes or confirm that a feeding tube remains in its proper position without the need for lengthy sterilization procedures between uses. | 05-10-2012 |
Timothy R. Nieman, North Salt Lake, UT US
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20120126499 | CONVERTIBLE CONVEYANCE METHOD AND APPARATUS - Devices and methods for convertibly changing the means and carrying capacity of a pedestrian are provided. Specifically the present disclosure comprises a backpack capable of being converted into a wheelbarrow for the purpose of transporting increased loads in emergency or varying conditions. The device may include a frame and satchel whereby a series of components are fastened to the frame in order provide for implements such as handles and rolling wheels for transportation of increased loads. The components of the system may include, for example, a frame, a satchel, handles, a wheel, and an axle. When assembled to convert the pack to a wheelbarrow configuration, the device may increase the safe carrying capacity of a pedestrian from 50-100 lbs. to 200-300 lbs. or more. | 05-24-2012 |
20140182140 | SAFETY CUTTING DEVICE - A safety cutting device includes a slidable insert that moves longitudinally within a cavity of a housing. The slidable insert has a cutting blade attached and moves within the housing from a safe position in which the blade is covered to an exposed position for cutting. The safety device has a release button positioned near an anterior end of the housing. A biasing member automatically retracts the blade when the release button is activated. | 07-03-2014 |
20150112132 | ELONGATE MEDICAL INSTRUMENT WITH SHEATH - An elongate medical instrument that may comprise steering mechanisms, optical sensors, light emitters, and/or fluid flow paths is disclosed. A removable sheath may be utilized to isolate the instrument from contamination when the instrument is used within the human body. The sheath may be disposable or reusable. In some instances, the elongate device may be used to position other components, such as elongate tubes. | 04-23-2015 |
20150305765 | TISSUE RESECTORS WITH CUTTING WIRES, HAND OPERATED TISSUE RESECTING SYSTEMS AND ASSOCIATED METHODS - A tissue resector includes an outer cannula with a cutting wire disposed therein. The outer cannula includes an opening that is configured to be associated with a cutting element of the cutting wire in such a way that when tissue is drawn into the opening of the cannula, a cutting element of the cutting wire can be rotated past the opening to engage and cut into and through the tissue. The outer cannula and the cutting wire may also be configured to enable aspiration of the tissue. A tissue resector according to this disclosure may be used with a hand-held, hand-operated rooter. | 10-29-2015 |