Nielsen, US
Alex Nielsen, Rexburg, ID US
Patent application number | Description | Published |
---|---|---|
20100094674 | Supply Chain Management Systems and Methods - Supply chain management (SCM) systems and methods are presented. In SCM ecosystems having multiple independent trading partners that can functions as peers, the trading partners likely lack a “single version of truth” with respect to retail data formats or transactions. The partners can utilize database connectors to interact with other peer partners by converting the partner's retail data from proprietary formats to a common transaction format understood by all connectors or by an SCM application stack constructed from SCM modules. The connectors can use a registry server to discover other connectors capable participating in a requested transaction relationship. SCM modules can be configured to support a transaction relationship according to the transaction relationships available to the peers' connectors. | 04-15-2010 |
Allan N. Nielsen, Dallas, TX US
Patent application number | Description | Published |
---|---|---|
20110241771 | ACTIVE MUTE SCHEME FOR AN AMPLIFIER - Conventional muting circuitry for amplifiers (which usually uses clamps) generally has about 20-30 dB of attenuation. Here, an integrated circuit or IC is provided that includes an amplifier, switch networks, and a controller. The controller provides control signals to the switch network to provide mute functionality by actively muting the amplifier. In particular, feedback is provided through at least one of the switch networks to drive the output of the amplifier to null or ground so as to provide 70-80 dB (or more) of attenuation. | 10-06-2011 |
Allan Nogueras Nielsen, Dallas, TX US
Patent application number | Description | Published |
---|---|---|
20100188155 | CLOSED LOOP RAMP UP FOR POP AND CLICK REDUCTION IN AN AMPLIFIER - To reduce pop or click during turn-on, a method and apparatus are provided. Initially, a plurality of current sources in the amplifier is actuated. The amplifier is transitioned from an off-state to an on-state in a class B amplifier mode by de-coupling each input node of an output stage of the amplifier from a voltage rail, and the amplifier is transitioned from the on-state in the class B amplifier mode to an on-state in a class AB amplifier mode by actuating at least a portion of an intermediate circuit in the amplifier. | 07-29-2010 |
Ben Nielsen, Eden Prairie, MN US
Patent application number | Description | Published |
---|---|---|
20110184588 | SYSTEM AND METHOD FOR ESTIMATING AND DETECTING SPEED - A system for determining instances when a vehicle's indicated speed exceeds a governing speed includes a receiver to receive information from which a vehicle's location envelope, indicated direction of travel, and indicated speed can be derived, and a processor. The processer is configured to ascertain a location envelope in which the vehicle is located, an indicated speed of the vehicle, and a direction of travel of the vehicle at a sample time. It is also configured to select the governing speed for the vehicle at the sample time, which includes ascertaining possible road segments with at least a portion within the location envelope, eliminating road segments with a road segment direction of travel inconsistent with the indicated direction of travel, and selecting as the governing speed a speed associated with a remaining road segment. The processor will then determine if the indicated speed exceeds the governing speed. | 07-28-2011 |
20120323404 | SYSTEM AND METHOD FOR ESTIMATING AND DETECTING SPEED - A system for determining instances when a vehicle's indicated speed exceeds a governing speed includes a receiver to receive information from which a vehicle's location envelope, indicated direction of travel, and indicated speed can be derived, and a processor. The processor is configured to ascertain a location envelope in which the vehicle is located, an indicated speed of the vehicle, and a direction of travel of the vehicle at a sample time. It is also configured to and select the governing speed for the vehicle at the sample time, which includes ascertain possible road segments with at least a portion within the location envelope, eliminate road segments with a road segment direction of travel inconsistent with the indicated direction of travel, and select as the governing speed a speed associated with a remaining road segment. The processor will then determine if the indicated speed exceeds the governing speed. | 12-20-2012 |
Benjamin Jason Nielsen, Prior Lake, MN US
Patent application number | Description | Published |
---|---|---|
20090287369 | Method and System for Providing Supplemental Services to Telematics Systems - The embodiments of the present innovation provide a method and system for providing supplemental services to telematics systems. The method and system receives data from a telematics provider in a non-proprietary format, parses the data, stores the data, provides the data to a third party application, obtains an output from the third party application, and transmits the output to a customer. The method and system may also receive data from any portable device, parse the data, store the data, provide the data to a third party application, obtain an output from the third party application, and transmit the output to a customer. | 11-19-2009 |
Bent L. Nielsen, Huntington, WV US
Patent application number | Description | Published |
---|---|---|
20090288913 | CLIMB-ASSIST DEVICE - A climbing assistance device having a connection assembly disposed at a predetermined location on the structure, a yoke attachable to a person, a counterweight connected to the yoke by a cable which passes through a pulley system, and a stabilizer operative to stabilize the counterweight to prevent rotation thereof. By employing the stabilizer, the counterweight remains stable during ascent and descent, and the load of the counterweight is controlled. | 11-26-2009 |
Blake Nielsen, Schaumberg, IL US
Patent application number | Description | Published |
---|---|---|
20100133209 | CONFIGURABLE DISPLAY SYSTEM AND MODULAR DISPLAY ARRANGEMENT FOR CONSUMER ELECTRONIC DEVICES - A method of displaying consumer electronic devices comprises supporting a plurality of rails on a frame in a generally parallel, spaced relationship and configuring each rail for slidable movement relative to the frame in a direction generally perpendicular to a longitudinal axis of each rail. A first row of display units is supported between a first adjacent pair of the rails and a second row of display units between a second adjacent pair of the rails, with each display unit comprising at least one of a device support unit and a plate. The plurality of display units are reconfigurable by exchanging the display units between different lateral positions within at least one of the first and second rows of display units and/or by exchanging at least one display unit between the first row and the second row of display units. | 06-03-2010 |
Blake Nielsen, Schaumburg, IL US
Patent application number | Description | Published |
---|---|---|
20090065454 | PRODUCT DISPLAY SYSTEM - A product display includes at least one shelf and a plurality of product displays. The at least one shelf is configured to receive a stack of product packages thereon. The product displays are pivotally mounted, at spaced intervals, along the at least one shelf. In a first position, each product display supports a product generally in front of the stack of product packages on the at least one shelf, and in a second position, each product display is pivotally moved away from a front of the stack of product packages to enable direct access to the stack of product packages. | 03-12-2009 |
Blake Nielsen, Chicago, IL US
Patent application number | Description | Published |
---|---|---|
20100118512 | Lighting strip shower cleaner - An elongated lighting strip is provided. The lighting strip is positioned inside of a shower or bathtub enclosure in order to both illuminate the enclosure as well as spray or diffuse and aqueous solution onto the enclosure. | 05-13-2010 |
Bo Hjort Nielsen, Jamaica Plain, MA US
Patent application number | Description | Published |
---|---|---|
20110173546 | INFORMATION MANAGEMENT - An approach to managing information makes use of a multi-program graphical user environment (e.g., a virtual desktop). The graphical environment includes a first part in which information elements are presented to a user. A user selection of one or more information elements is accepted and corresponding representations of those elements are formed in another part of the graphical environment. The representations formed in the other part of the graphical environment are persistent as further information elements are presented to the user in the first part of the environment. In some examples, information elements may be classified by users such that application of and access to classifications is mediated a privilege system. | 07-14-2011 |
20140181742 | MANAGING INTERACTIONS WITH DATA HAVING MEMBERSHIP IN MULTIPLE GROUPINGS - Interactions with data stored in a data storage system are managed through a view of an interface provided on a display. Information specifying multiple data elements and multiple groupings of related data elements is received. At least one of the data elements is a member of multiple of the groupings. A view is rendered that includes tokens representing respective data elements. At least some tokens include a selectable indicator including portions that indicate membership of the data element represented by that token in each of multiple groupings of related data elements. A first selection of a portion of one of the selectable indicators is received, corresponding to a first selected grouping of related data elements. In response to the first selection, tokens representing one or more other members of the first selected grouping of related data elements are rendered in the view. | 06-26-2014 |
Charles A. Nielsen, Midland, MI US
Patent application number | Description | Published |
---|---|---|
20090215190 | APPARATUS AND METHOD FOR EXOTHERMIC AND ENDOTHERMIC REACTIONS - The present invention generally relates to an apparatus and method for running a plurality of essentially simultaneous exothermic reactions, endothermic reactions, or a combination thereof in sealed reactors and obtaining physico-chemical data, preferably temperature data, and, optionally, time data, for the reactions, wherein reaction mixtures in the sealed reactors are adiabatically thermally insulated from one another so that temperature in one sealed reactor does not materially affect temperature in any other, including an adjacent, sealed reactor. | 08-27-2009 |
Curtis Nielsen, Rexburg, ID US
Curtis W. Nielsen, Rexburg, ID US
Patent application number | Description | Published |
---|---|---|
20100313146 | METHODS AND SYSTEMS RELATING TO AN AUGMENTED VIRTUALITY ENVIRONMENT - Systems and methods relating to an augmented virtuality system are disclosed. A method of operating an augmented virtuality system may comprise displaying imagery of a real-world environment in an operating picture. The method may further include displaying a plurality of virtual icons in the operating picture representing at least some assets of a plurality of assets positioned in the real-world environment. Additionally, the method may include displaying at least one virtual item in the operating picture representing data sensed by one or more of the assets of the plurality of assets and remotely controlling at least one asset of the plurality of assets by interacting with a virtual icon associated with the at least one asset. | 12-09-2010 |
20110054689 | ROBOTS, SYSTEMS, AND METHODS FOR HAZARD EVALUATION AND VISUALIZATION - A robot includes a hazard sensor, a locomotor, and a system controller. The robot senses a hazard intensity at a location of the robot, moves to a new location in response to the hazard intensity, and autonomously repeats the sensing and moving to determine multiple hazard levels at multiple locations. The robot may also include a communicator to communicate the multiple hazard levels to a remote controller. The remote controller includes a communicator for sending user commands to the robot and receiving the hazard levels from the robot. A graphical user interface displays an environment map of the environment proximate the robot and a scale for indicating a hazard intensity. A hazard indicator corresponds to a robot position in the environment map and graphically indicates the hazard intensity at the robot position relative to the scale. | 03-03-2011 |
Cynthia A. Nielsen, Commerce, MI US
Patent application number | Description | Published |
---|---|---|
20100230018 | THEFT DETERRENT ANTI-SCANNING DEVICE - A theft deterrent anti-scanning device incorporating a metallic anti-scanning and shielding layer laminated into various articles to encapsulate cards and financial documents which carry sensitive personal financial information that can be read by traditional RIFD scanning devices. However, if you incorporate a Faraday cage to block RF frequencies up to 2.4 gigahertz, the card must be entirely encapsulated for the RF shielding to be effective. A GPS tracking device may be added in order to retrieve lost or stolen information, and the entire device may be configured to become portion of a purse or an enclosable pouch. In other aspects of the present invention, an enclosable pouch of description in the application may render the pouch to be water proof, fire resistant, and to be protected from theft. | 09-16-2010 |
Dale P. Nielsen, Amherst, MA US
Patent application number | Description | Published |
---|---|---|
20120084375 | APPARATUS AND METHODS FOR CONTROLLING THE TRANSMISSION OF MESSAGES - The invention provides systems, mechanisms and techniques for controlling transmission of outbound messages, such as e-mail or other types of messages, onto a computer network from an originator computer system. Connection equipment can authenticate and authorize the connection for the computer user and can capture and map originator network address information assigned to the originator computer system. A quota server can then determine if the message count exceeds the message limit for the originator identity associated with the outbound message Embodiments of the invention control message transmission from a sending or origination point prior to the messages being transmitted on the computer network, resources of a computer network are conserved and these embodiments prevent computer users from transmitting large amounts of outbound messages in excess of the message limits. | 04-05-2012 |
Daniel Nielsen, Burlington, VT US
Patent application number | Description | Published |
---|---|---|
20140066529 | Nanoporous Silica Polyamine Composites with Surface-bound Zirconium (IV) and Methods of Use - Silica polyamine composites (SPC) made from silanized amorphous nano-porous silica gel and poly(allylamine) (BP-1) were functionalized with phosphorus acid using the Mannich reaction, resulting in a phosphonic acid modified composite (BPAP). Zirconium (IV) was immobilized on BPAP. Arsenate anions strongly adsorbed on the ZrBPAP composite in the pH range 2 to 8, while arsenite only adsorbed well at pH 10. Regeneration of the resin was carried out successfully for As(V) and As(III) using 2M-H | 03-06-2014 |
David Nielsen, Champaign, IL US
Patent application number | Description | Published |
---|---|---|
20100044344 | Silicon Nanoparticle Formation From Silicon Powder and Hexacholorplatinic Acid - A silicon nanoparticle formation method that can rapidly produce substantial quantities of silicon nanoparticles, which are readily recoverable for subsequent uses. Methods of the invention treat silicon powder in hexachloroplatinic acid. The treated silicon powder is then etched with an etching solution of HF/H | 02-25-2010 |
D. Jeffrey Nielsen, Nibley, UT US
Patent application number | Description | Published |
---|---|---|
20100041522 | METHOD AND SYSTEM FOR VARYING STRIDE IN AN ELLIPTICAL EXERCISE MACHINE - Disclosed is an exercise machine, and particularly a front or rear mount elliptical or elliptical-type machine, comprising: (a) a support structure; (b) a drive component pivotally coupled to the support structure and configured to rotate about a first pivot axis; (c) a reciprocating foot support configured to travel about a closed path having a stride length upon rotation of the drive component; (d) a coupling configuration configured to support the reciprocating foot support about the drive component at a position radially offset from the first pivot axis, the coupling configuration pivotally coupled to the drive component about a second pivot axis; and (e) an adjustment mechanism configured to enable the coupling configuration to pivot about the second pivot axis between at least two adjustment positions to vary the radial offset of the reciprocating foot support with respect to the first pivot axis. | 02-18-2010 |
Elizabeth Nielsen, Bountiful, UT US
Patent application number | Description | Published |
---|---|---|
20120289117 | MODULAR FIGURINE AND ACCESSORY SYSTEM - The present disclosure provides various systems and methods for a customized modular figurine and accessory system having any number of components. A user may select from various possible components and accessories to assemble a unique and customized modular figurine using the artistic expression of the user. The customized modular figurine and accessory system may include a plurality of modular components, for example, a torso component, a head component, a wing component, and a skirt component, each of these individual components may then be selected by an individual to create and assemble a customized modular figurine. A support riser may extend into or through various components of an assembled customized modular figurine. A customizable display component may also be provided. | 11-15-2012 |
Erik R. Nielsen, Houston, TX US
Patent application number | Description | Published |
---|---|---|
20110095715 | System and Method for Cooling Using Counter-Rotating Fans - A system includes two counter-rotating electric fans. A cooling controller is configured to run the fans at first and second operating points responsive to a measured value of a parameter. The first and second operating points correspond to first and second different required volumes per unit time of air flow. Rotational speeds of the fans at the first and second operating points define first and second different rotational speed offsets. | 04-28-2011 |
20110130891 | HEATSINK WITH A PLURALITY OF FANS - In at least some embodiments, an apparatus comprises an electronic component and a heatsink for the electronic component. The apparatus further comprises a plurality of fans mounted to the heatsink. The plurality of fans comprises a first fan that provides an airflow for the heatsink and a second fan that selectively modifies the airflow. | 06-02-2011 |
Hugh C. Nielsen, Provo, UT US
Patent application number | Description | Published |
---|---|---|
20090238109 | METHOD FOR QUALIFIED ROUTE BUILDING IN A WIRELESS NETWORK - A method of establishing a qualified route in a mesh network includes transmitting a route-discovery request from a source node such that transmitting includes transmitting the route-discovery request from the source node to at least one intermediate node that is a neighbor node to the source node, receiving the route-discovery request from an intermediate node at the destination node, and updating a route-discovery table for the intermediate node such that the route between the source node and the destination node is the only qualified route. | 09-24-2009 |
Issac R. Nielsen, Redford, MI US
Patent application number | Description | Published |
---|---|---|
20100127857 | DIAGNOSTIC SYSTEM HAVING A WAKE-UP CIRCUIT - A system comprises an electronic device including at least one input for receiving at least one enable signal and external data. The system also comprises a wake-up circuit including at least one input for receiving at least one informational signal, an output for sending the at least one enable signal to the electronic device, and a data interface for external configuration of the wake-up circuit. | 05-27-2010 |
Jacob Thymann Nielsen, Houston, TX US
Patent application number | Description | Published |
---|---|---|
20110267921 | MULTICOMPONENT SEISMIC INVERSION OF VSP DATA - A method for seismic inversion of vertical seismic profile (VSP) data in an oilfield. The method includes obtaining an initial velocity model of a subterranean formation including acoustic velocities of wave propagation in proximity to the wellbore, determining an acquisition geometry for obtaining the VSP data including receiver locations within the wellbore and a source location, performing a seismic survey to obtain the VSP data based on the acquisition geometry, analyzing arrival signals of the VSP data to generate transit time data for wave propagation from the source location to the receiver locations, modifying the initial velocity model to generate an updated velocity model by performing a tomographic inversion of the transit time data, generating an elastic model of the subterranean formation by performing the seismic inversion of the VSP data using the updated velocity model, and adjusting the operations of the oilfield based on the elastic model. | 11-03-2011 |
Jeffrey Nielsen, Corvallis, OR US
Patent application number | Description | Published |
---|---|---|
20120272896 | APPARATUS TO CAPTURE AEROSOLS, FLUID JETTING APPARATUS, AND AEROSOL DIVERTERS - Apparatus to capture aerosols, fluid jetting apparatus, and aerosol diverters are disclosed. An example aerosol capture apparatus includes a corona wire to generate ions, and a reference plate positioned below the corona wire and above a substrate on which a fluid is to be deposited, the reference plate to provide a reference potential to direct the ions toward the reference plate to force aerosol particles associated with the fluid toward the reference plate. | 11-01-2012 |
Jeffrey A. Nielsen, Corvallis, OR US
Patent application number | Description | Published |
---|---|---|
20080259148 | Handheld and/or mountable fluid-ejection device having tip-extension assembly and/or tubings - A fluid-ejection device includes a handheld and/or mountable enclosure, a removable tip having a fluid-ejection mechanism, a first fitting extending from the enclosure and receptive to placement of the removable tip thereon, and a controller situated within the enclosure to cause the removable tip to eject the fluid. The fluid-ejection device may also include tip-extension assembly having an electrical cable connecting to the controller and having a second fitting receptive to placement of the removable tip thereon. The electrical cable permits the removable tip to be located substantially independently of the enclosure. The fluid-ejection device may further include tubings fluidically couplable with the removable tip through at least one of the first and second fittings to provide fluid to the removable tip and to regulate backpressure of the fluid within the removable tip. | 10-23-2008 |
20090096839 | FLUID EJECTION DEVICE - A fluid ejection device includes a fluid chamber, a resistor formed within the fluid chamber, and an orifice communicated with the fluid chamber, wherein the fluid ejection device is adapted to eject drops of a non-aqueous fluid, and wherein a ratio of a square root of an area of the resistor to a diameter of the orifice is in a range of approximately 1.75 to approximately 2.25. | 04-16-2009 |
20100304496 | FLUID DISPENSER WITH LOW SURFACE ENERGY ORIFICE LAYER FOR PRECISE FLUID DISPENSING - The present invention is embodied in a method for precisely dispensing fluid, including treating an orifice of a fluid dispensing apparatus during a fabrication process by applying a low surface energy material layer onto the orifice, adjusting a thickness of the low surface energy material coating to a predetermined threshold and limiting backpressure of a low dead volume fluid delivery system coupled to the orifice to reduce interference or interruptions for precisely dispensing the fluid. | 12-02-2010 |
20120056943 | FLUID-EJECTION PRINTHEAD DIE HAVING AN ELECTROCHEMICAL CELL - A fluid-ejection printhead die includes a fluid-ejection firing element and an electrochemical cell. The fluid-ejection firing element is to cause droplets of fluid to be ejected from the fluid-ejection printhead die. The electrochemical cell is to measure an electrical property of the fluid. The fluid-ejection firing element and the electrochemical cell are both part of the fluid-ejection printhead die. | 03-08-2012 |
20140193309 | Liquid Dispenser Cassette - A liquid dispenser cassette includes a frame, dispense head assemblies, and a one-piece integrated slot extender. The frame defines openings. The dispense head assemblies are mounted on the frame. The dispense head assemblies include dispense head dies at least partially exposed through the corresponding openings. The dispense head dies defines top slots. The slot extender is mounted on the dispense head assemblies. The slot extender has reservoirs defining drain openings mated to the corresponding top slots. | 07-10-2014 |
20140217201 | DISPENSING HEADS WITH FLUID PUDDLE LIMITING SURFACE FEATURES - Methods and apparatus are provided related to fluid dispensing heads. A dispense head is formed to define a plurality of fluid jetting nozzles and a surface pattern. The surface pattern is characterized by one or more voids extending inward from an outer surface of the dispense head. Fluid puddle formation during operation of the dispense head is limited in volume by way of the surface pattern. Fluid puddle limiting reduces or eliminates dispensing errors to an entity, undesirable artifacts from resulting on a printed media, or similar problems. | 08-07-2014 |
Jeffrey A. Nielsen US
Patent application number | Description | Published |
---|---|---|
20110157279 | Multiple drop weight printhead and methods of fabrication and use - A printhead includes a chamber layer and at least two orifice layers. A first orifice layer is disposed on the chamber layer, and a second orifice layer is disposed on the first orifice layer. The second orifice layer has at least one counterbore formed therein. A first nozzle is formed through both orifice layers and produces droplets of a first drop weight. A second nozzle is formed through the first orifice layer, coincident with the counterbore, and produces droplets of a second drop weight that is different than the first drop weight. In one embodiment, the printhead is used in a stand-alone fluid-dispensing device. | 06-30-2011 |
Jennifer Nielsen, Arlington, VA US
Patent application number | Description | Published |
---|---|---|
20100252460 | Giftwear greeting card and packaging - A personally crafted greeting card adapted to insert over a gift is disclosed. The greeting card includes a top horizontal panel and two vertical panels. The top horizontal panel is adhered to the vertical panels by means of adhesive tapes to form a receptacle for inserting over a gift. The vertical panels are designed in T-shirt shape including front and back surface for inputting personalized messages over it for imparting a personal touch while presenting the gift to a recipient. The greeting card is inserted over the neck of a wine or other spirit bottle, or gifts with similar neck configurations through a cutout orifice formed at the center of the top horizontal panel in the unfolded position. The invention includes a packaging system for holding the greeting cards in their greeting card covers. The packaging system includes a crate for holding a plurality of greeting cards in their greeting card covers. | 10-07-2010 |
Jens Nielsen, Traverse City, MI US
Patent application number | Description | Published |
---|---|---|
20120041450 | MINIMAL ACCESS TOOL - A minimal access tool includes a frame arranged to be attached to an arm of a user, a tool shaft having a proximal end and a distal end, where the tool shaft proximal end is connected to the frame. The tool further includes an input joint having a first end connected to the frame and a second end arranged to receive user input, the input joint including a virtual center-of-rotation (VC) mechanism which provides a center of rotation that generally coincides with a wrist joint of the user. An output joint is connected to the tool shaft distal end, where the output joint is coupled to the input joint via a mechanical transmission connected therebetween to correlate motion of the input joint to motion of the output joint. | 02-16-2012 |
20140142595 | MINIMAL ACCESS TOOL - A minimal access tool includes a frame arranged to be attached to an arm of a user, a tool shaft having a proximal end and a distal end, where the tool shaft proximal end is connected to the frame. The tool further includes an input joint having a first end connected to the frame and a second end arranged to receive user input, the input joint including a virtual center-of-rotation (VC) mechanism which provides a center of rotation that generally coincides with a wrist joint of the user. An output joint is connected to the tool shaft distal end, where the output joint is coupled to the input joint via a mechanical transmission connected therebetween to correlate motion of the input joint to motion of the output joint. | 05-22-2014 |
John A. Nielsen, Woodbury, MN US
Patent application number | Description | Published |
---|---|---|
20100143654 | ADHESIVE ARTICLES AND RELEASE LINERS - The present application is directed to adhesive articles and release liners. Namely, the present application is directed to an article comprising an adhesive layer with a structured surface. The structured surface comprises a first groove and a second groove recessed into the adhesive layer from a reference plane defined by the adhesive surface on either rim of the groove. In some embodiments, the second groove is contained within the first groove, and in other embodiments the grooves are separate. The first groove and the second groove have walls. The wall angle of the first groove with respect to the reference plane is non-zero and is smaller than the wall angle of the second groove with respect to the reference plane. The application is also directed to release liners for the adhesive article, wherein the surface of the release liner is the inverse of the adhesive surface. | 06-10-2010 |
20130101775 | MULTILAYER FILM - The present application is directed to a multilayer film The film comprises a thermoplastic receptor layer comprising a polyurethane, a thermoplastic core layer on the receptor layer comprising an acidic group or an anhydride group, and a thermoplastic primer layer on the core layer opposite the receptor layer comprising a nitrogen containing polymer. In some embodiments, the multilayer film includes additional layers. For example, an adhesive layer may be on the primer layer opposite the core layer. In another embodiment, a release layer is on the adhesive layer opposite the primer layer. In another embodiment, a liner layer is on the release layer opposite the adhesive layer. | 04-25-2013 |
20140141214 | GRAPHIC ARTICLE - The present application is directed to articles useful as graphic films. Specifically, the present application is directed to an article comprising a film layer, the film layer comprising a polymer blend comprising a thermoplastic polyurethane and a cellulose ester, and an ink layer adjacent to at least one surface of the film. In some embodiments, the cellulose ester is a cellulose acetate butyrate. In some embodiments, the cellulose ester is a cellulose acetate propionate. | 05-22-2014 |
20140154505 | GRAPHIC ARTICLE - The present application is directed to articles useful as graphic films. Specifically, the present application is directed to a multilayer film, at least one layer of the multilayer film comprising a polymer blend comprising a thermoplastic polyurethane and a cellulose ester. In some embodiments, a second layer of the multilayer film comprises thermoplastic polyurethane and the cellulose ester. In some embodiments, a second layer of the multilayer film comprises a material different from the polymer blend. | 06-05-2014 |
20140158278 | GRAPHIC ARTICLE - The present application is directed to methods of using articles useful as graphic films. Specifically, the present application is directed to a method of displaying an image comprising providing a substrate with an irregular surface and applying an adhesive article to the substrate. The adhesive article comprises a film layer, and an adhesive layer. The film layer comprises a thermoplastic polyurethane and a cellulose ester. The adhesive layer adheres the adhesive article to the substrate. | 06-12-2014 |
20140162010 | GRAPHIC ARTICLE - The present application is directed to articles useful as graphic films. Specifically, the present application is directed to an article comprising a film layer, the film layer comprising a polymer blend comprising a thermoplastic polyurethane and a cellulose ester, and an adhesive layer adjacent the film layer. | 06-12-2014 |
20140262013 | ADHERING GRAPHIC FILMS ON IRREGULAR SUBSTRATES - Methods of adhering graphic film on an irregular substrate are disclosed. The methods includes providing a polymer film composite having two or more layers with at least one layer having a glass transition temperature of at least about 40° C., the polymer film composite having a first side and a second side, and an adhesive layer disposed on the second side. Then the method includes, positioning the adhesive layer against the irregular substrate, heating the polymer film composite, and pressing the heated polymer film against the irregular substrate. | 09-18-2014 |
John Oliver Nielsen, Cullman, AL US
Patent application number | Description | Published |
---|---|---|
20120205602 | ELECTRIC WEB FENCE - An electric fence including a web of galvanized, high-tensile strength steel wires coupled to and between a pair of posts, the web including a plurality of substantially horizontally extending wires arranged substantially parallel to one another, and a plurality of substantially vertically extending wires arranged substantially parallel to one another and extending to and between each of the horizontally extending wires to form a plurality of wire rectangles, each rectangle having a desired size. The construction and arrangement of the web enables the web to be energized using less energy than conventional fencing. | 08-16-2012 |
Jonathan Kirk Nielsen, Memphis, TN US
Patent application number | Description | Published |
---|---|---|
20100131070 | ANATOMICAL MOTION HINGED PROSTHESIS - A hinged knee prosthesis ( | 05-27-2010 |
Jon-Fredrik Nielsen, West Bloomfield, MI US
Patent application number | Description | Published |
---|---|---|
20100102816 | EDDY-CURRENT ARTIFACT REDUCTION IN BALANCED STEADY-STATE FREE PRECESSION MAGNETIC RESONANCE IMAGING - Magnetic resonance imaging techniques are described that utilize bSSFP sequences in which two or more gradient waveforms are interleaved in a “groupwise” fashion, i.e., each waveform is executed consecutively two or more times before switching to the other waveform, where “N” counts the number of times each waveform is executed consecutively. As a result, embodiments of the present disclosure can mitigate steady-state signal distortions or artifacts in interleaved balanced steady-state free precession (bSSFP) caused by slightly unbalanced eddy-current fields. Related MRI systems are also described. | 04-29-2010 |
20100109665 | FAST VELOCITY MEASUREMENTS USING BALANCED SSFP MAGNETIC RESONANCE IMAGING - Referenceless techniques for flow imaging are described that exploit a refocusing property of balanced steady state free precession (“SSFP”) magnetic resonance imaging (“MRI”), and achieve up to approximately a 50% reduction in total scan time. With the echo time set to one half of the sequence repetition time (TE=TR/2), non-flow-related image phase tends to vary smoothly across the field-of-view, and can be estimated from static tissue regions to produce a phase reference for nearby voxels containing flowing blood. These approaches produce accurate in vivo one-dimensional velocity estimates in half the scan time compared with conventional balanced SSFP phase-contrast methods. The feasibility of referenceless time-resolved 3D flow imaging (called “7D” flow) is demonstrated for a carotid bifurcation application from just three acquisitions. Related systems are also described. Other attributes such as blood acceleration can also be imaged with such techniques. | 05-06-2010 |
Karsten V. Nielsen, Depere, WI US
Patent application number | Description | Published |
---|---|---|
20110284385 | Method and Apparatus For Anodizing Objects - A method and apparatus for electrolytically treating a surface of a component includes a reaction chamber, a transport chamber and a fluid return path. The reaction chamber is adapted for placing at least a portion of the component therein, and holds a reaction fluid. Fluid enters the reaction chamber through a plurality of inlets. Each inlet directs the fluid toward the component at one or more non-zero vertical angles, and at one or more non-zero horizontal angles. The reaction chamber is a fixture having a cover with an underside shaped to direct the fluid to the surface of the component, such as by having a plurality of slopes. The inlets are through a material that is electrically non-conductive, such as ceramic, plastic, PVC, and fiber reinforced plastic, and/or the fixture further includes a titanium cathode ring that can be vertically adjacent the non-conductive material. | 11-24-2011 |
Kurt Nielsen, Chadds Ford, PA US
Patent application number | Description | Published |
---|---|---|
20080305171 | PYRROLOPYRAZINE, FORMULATIONS, METHODS OF MANUFACTURE, AND METHODS OF USE THERE - Disclosed herein is a pyrrolopyrazine COMPOUND I having defined amounts of R isomer, particle size, and stability. Also disclosed are pyrrolopyrazine oral dosage forms comprising the described COMPOUND I material as well as methods of treating disorders amenable to therapy using COMPOUND I. | 12-11-2008 |
20090312430 | COLCHICINE SOLID-STATE FORMS; METHODS OF MAKING; AND METHODS OF USE THEREOF - Disclosed are new colchicine solid-state forms, methods of preparing the solid-state forms, as well as formulations prepared therefrom and uses thereof. | 12-17-2009 |
20110178180 | DEUTERIUM-ENRICHED COLCHICINE, THIOCOLCHICINE, AND DERIVATIVES THEREOF; METHODS OF PREPARATION; AND USE THEREOF - Disclosed herein are deuterium-enriched colchicine, thiocolchicine, and derivatives thereof. The deuterium-enriched compounds are useful as, an antiproliferative agent, a muscle relaxant, an anti-inflammatory agent, or an anti-gout agent. | 07-21-2011 |
20130116330 | COLCHICINE SOLID-STATE FORMS; METHODS OF MAKING; AND METHODS OF USE THEREOF - Disclosed are new colchicine solid-state forms, methods of preparing the solid-state forms, as well as formulations prepared therefrom and uses thereof. | 05-09-2013 |
Kurt R. Nielsen, Chadds Ford, PA US
Patent application number | Description | Published |
---|---|---|
20080220076 | Active Agent Formulations, Methods of Making, and Methods of Use - Active agent compositions comprising active agent particles having an effective average particle size of less than 2000 nm, wherein the compositions comprise a particle sequestrant are disclosed. Compositions having an effective average particle size of less than 2000 nm, wherein the compositions comprise no added surfactants, phospholipids, or combinations thereof, are also disclosed. | 09-11-2008 |
20090163540 | Quinine Sulfate Polymorphs, Processes of Preparing, Compositions and Uses Thereof - Disclosed are new quinine sulfate polymorphs, methods of making the polymorphs as well as formulations prepared therefrom and uses thereof. | 06-25-2009 |
20090163561 | AMORPHOUS METAXALONE AND AMORPHOUS DISPERSIONS THEREOF - The present invention provides various amorphous forms of the compound metaxalone (I), such as solid amorphous metaxalone and amorphous dispersions comprising metaxalone. The present invention further provides pharmaceutical compositions comprising these amorphous forms, and methods of their preparation. The present invention additionally provides methods of treating painful conditions (e.g., such as painful musculoskeletal conditions) comprising administering a therapeutically effective amount of any one of these amorphous forms to a subject in need thereof. | 06-25-2009 |
20090318561 | COLCHICINE PRODUCTS, METHOD OF MANUFACTURE, AND METHODS OF USE - Disclosed herein is a method of using colchicine. In one embodiment, the method comprises administering to a patient colchicine and a substrate of cytochrome P450 1A2 and monitoring the patient during administration of colchicine and the substrate for an adverse event. Also disclosed are articles of manufacture comprising a container containing a dosage form of colchicine and a method of manufacturing a colchicine product. | 12-24-2009 |
20110184061 | THIOCOLCHICINE AND COLCHICINE ANALOGS, METHODS OF MAKING AND METHODS OF USE THEREOF - Disclosed herein are thiocolchicine and colchicine analogs and derivatives suitable for use as a muscle relaxant, an anti-inflammatory agent, an anti-gout agent, an anti-proliferative agent, or an anti-cancer agent; methods of making the compounds, and compositions comprising the compounds. | 07-28-2011 |
Lars Christian Nielsen, Dallas, TX US
Patent application number | Description | Published |
---|---|---|
20110251858 | INSURANCE ALERT SYSTEM AND METHOD - An insurance alert system comprises an alert module executable by a processor, the alert module configured to automatically interface with a plurality of different insurance providers for an insurance broker. The alert module is configured to obtain and aggregate alert data from the plurality of different insurance providers corresponding to customers of the insurance broker, the alert data corresponding to insurance policies of the customers with the respective insurance providers. | 10-13-2011 |
Lars K. Nielsen, Denver, NC US
Patent application number | Description | Published |
---|---|---|
20090034921 | Distribution Cable Assembly Having Overmolded Mid-Span Access Location - A fiber optic cable assembly comprising a first fiber optic cable having pre-selected optical fibers pre-terminated and branched at a cable access point, a second cable optically connected to the pre-terminated optical fibers, and a flexible body encapsulating the cable access point. A method for manufacturing a fiber optic cable assembly comprising providing a fiber optic cable, making an opening in the cable for access, pre-terminating pre-selected optical fibers, optically connecting the pre-selected optical fibers with optical fibers of a tether cable, and encapsulating at least a portion of the cable access location within a flexible overmolded body. | 02-05-2009 |
Lennart Nielsen, Edina, MN US
Loretta Nielsen, Millington, NJ US
Patent application number | Description | Published |
---|---|---|
20080286239 | COMBINED TUMOR SUPPRESSOR GENE THERAPY AND CHEMOTHERAPY IN THE TREATMENT OF NEOPLASMS - In one embodiment, this invention provides methods of treating mammalian cancer or hyperproliferative cells, said method comprising contacting said cells with a tumor suppressor protein or tumor suppressor nucleic acid and also contacting said cell with at least one adjunctive anti-cancer agent. The invention also provides for a pharmacological composition comprising a tumor suppressor protein or a tumor suppressor nucleic acid and at least one adjunctive anti-cancer agent, and a kit for the treatment of mammalian cancer or hyperproliferative cells. | 11-20-2008 |
Mark Nielsen, Cambridge, MN US
Patent application number | Description | Published |
---|---|---|
20120037231 | CEMENTIOUS WASHOUT CONTAINER AND METHOD FOR SAME - A cementious washout container includes a container body having a container reservoir. A hinged chute assembly is rotatably coupled with an upper portion of the container body. The hinged chute assembly includes a chute panel, and a hopper screen coupled with the chute panel. The hopper screen includes perforations overlying the container body. A container drain is positioned at a lower end of the container body, and a container valve is movably coupled over the container drain. The cementious washout container retains and stores washout water and fine particles from multiple loads of cement or concrete and consolidates the washout water and fine particles for a single delivery of the same without requiring multiple separate deliveries of these wastes in multiple trucks. | 02-16-2012 |
Mark D. Nielsen, Austin, TX US
Patent application number | Description | Published |
---|---|---|
20100020727 | SYSTEM AND METHOD OF USING DIAMETER BASED SIGNALING TO ACTIVATE AND DEACTIVATE SUBSCRIBER CENTRIC, VISUALLY RENDERED, SERVICES - A system and method is provided for providing using Diameter based signaling to activate and deactivate subscriber centric, visually rendered, services. The system is implemented in a computer infrastructure which includes computer executable code tangibly embodied on a computer readable medium. The executable code is operable to activate and deactivate subscriber centric, visually rendered, services using a Diameter based signaling protocol and support home subscriber server (HSS) based subscriber profiles that pertain to visual characteristics. | 01-28-2010 |
20100041369 | SYSTEM AND METHOD OF USING DIAMETER BASED SIGNALING TO SUPPORT BILLING MODELS FOR VISUALLY RENDERED SERVICES - A system and method of using Diameter based signaling is provided to track usage to support multiple billing models for visually rendered revenue generating services in an IP Multimedia subsystem based network. The system includes a computer system includes first program instructions to provide usage information to an accounting platform for processing charging information for visually rendered services in an IP Multimedia subsystem based network. The computer system also comprises a computer readable media which stores the first program instructions and a central processing unit to execute the first program instructions. | 02-18-2010 |
20100203903 | SYSTEM AND METHODS FOR PROVIDING LOCATION INFORMATION USING LOCATION BASED QUEUES - A location based service and method configured to provide a mechanism for delivering location to a subscribing user using a location queuing system. The method is implemented on a computing infrastructure and includes receiving one or more SIP (Session Initiation Protocol) messages with location information of a user. The method further includes publishing the location information to a location system queue with related timestamp information | 08-12-2010 |
20110131197 | OPTIMIZING CACHING PERIOD OF LOCATION DATA FOR NETWORK BASED LOCATION SERVICES - A system and associated method for optimizing caching period of location data for network based location services. A location caching server receives a location request from a mobile device. The location caching server calculates, pursuant to a predefined calculation rule, a caching period of a location cache entry for the mobile device based on a precision level requested by the mobile device and a service precision level assigned for a type of location service for which the location request was made. The location caching server obtains real location data of the mobile device of the calculated caching period is expired. The location caching server subsequently adjusts the caching period based on a distance traveled by the mobile device pursuant to a predefined adjustment rule, and updates the location cache entry. | 06-02-2011 |
20110252054 | SYSTEMS AND METHODS OF NETWORKING ENHANCEMENTS USING LOCATION BASED SERVICES - A location based service and method configured to provide a mechanism for information to a subscribing user. The method is implemented on a computing infrastructure and includes querying one or more databases for matching information of a third party that is associated with one or more mobile devices that pass within a predefined location at one or more predefined intervals. The method further includes providing location information to a subscribing user of the one or more mobile devices that have the matching information and pass within the predefined location. | 10-13-2011 |
20120276931 | SYSTEMS AND METHODS OF NETWORKING ENHANCEMENTS USING LOCATION BASED SERVICES - A location based service and method configured to provide a mechanism for information to a subscribing user. The method is implemented on a computing infrastructure and includes querying one or more databases for matching information of a third party that is associated with one or more mobile devices that pass within a predefined location at one or more predefined intervals. The method further includes providing location information to a subscribing user of the one or more mobile devices that have the matching information and pass within the predefined location. | 11-01-2012 |
20130295968 | SYSTEMS AND METHODS OF NETWORKING ENHANCEMENTS USING LOCATION BASED SERVICES - A location based service and method configured to provide a mechanism for information to a subscribing user. The method is implemented on a computing infrastructure and includes querying one or more databases for matching information of a third party that is associated with one or more mobile devices that pass within a predefined location at one or more predefined intervals. The method further includes providing location information to a subscribing user of the one or more mobile devices that have the matching information and pass within the predefined location. | 11-07-2013 |
20130346611 | SYSTEM AND METHOD OF USING DIAMETER BASED SIGNALING TO ACTIVATE AND DEACTIVATE SUBSCRIBER CENTRIC, VISUALLY RENDERED, SERVICES - A system and method are provided for providing using Diameter based signaling to activate and deactivate subscriber centric, visually rendered, services. The system is implemented in a computer infrastructure which includes computer executable code tangibly embodied on a computer readable medium. The executable code is operable to activate and deactivate subscriber centric, visually rendered, services using a Diameter based signaling protocol and support home subscriber server (HSS) based subscriber profiles that pertain to visual characteristics. | 12-26-2013 |
Mark T. Nielsen, Nicholasville, KY US
Patent application number | Description | Published |
---|---|---|
20100235938 | Nicotiana Nucleic Acid Molecules and Uses Thereof - The present invention features | 09-16-2010 |
20110289836 | USE OF CHLORATE, SULFUR OR OZONE TO REDUCE TOBACCO SPECIFIC NITROSAMINES - A method is provided for reducing levels of tobacco specific nitrosamines (TSNA) in tobacco during barn curing. The method includes contacting tobacco with chlorate, sulfur, ozone or combinations thereof in amounts effective for controlling or reducing bacterial an/or fungal populations on or in tobacco. | 12-01-2011 |
20120199148 | TOBACCO PLANTS HAVING A MUTATION IN A NICOTINE DEMETHYLASE GENE - The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. | 08-09-2012 |
20120216309 | NOVEL TOBACCO COMPOSITIONS AND METHODS OF MAKING - The present disclosure describes tobacco varieties having reduced levels of DVTs, methods of making such varieties, and tobacco compositions including such varieties. | 08-23-2012 |
20120222689 | TOBACCO INBRED PLANTS ALBEX1F AND ALBEX1MS - The present invention provides tobacco inbred plants ALBEX1F and ALBEX1MS. The present invention also provides parts of such plants and products made from those parts. The present invention also includes progeny of the provided plants including hybrids. | 09-06-2012 |
20130074858 | TOBACCO PLANTS HAVING REDUCED NICOTINE DEMETHYLASE ACTIVITY - The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nomicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof. | 03-28-2013 |
20130081157 | TOBACCO PLANTS HAVING REDUCED NICOTINE DEMETHYLASE ACTIVITY - The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof. | 03-28-2013 |
20130233742 | Container Device for Tobacco Articles - Some embodiments of a tobacco product package device can be used to enhance freshness and other characteristics of tobacco products or other products contained therein. Certain features can improve product freshness both during shelf life and during consumer use. | 09-12-2013 |
20140021077 | Container Device for Tobacco Articles - Some embodiments of a tobacco product package device can be used to enhance freshness and other characteristics of tobacco products or other products contained therein. Certain features can improve product freshness both during shelf life and during consumer use. | 01-23-2014 |
20140123987 | NICOTIANA NUCLEIC ACID MOLECULES AND USES THEREOF - The present invention features | 05-08-2014 |
20140190498 | NICOTIANA NUCLEIC ACID MOLECULES AND USES THEREOF - The present invention features | 07-10-2014 |
20140261481 | NITRITE-DEGRADING AND TSNA-DEGRADING BACTERIA AND METHODS OF MAKING AND USING - Provided herein are bacterial strains that are capable of degrading nitrite and/or TSNAs. Also provided herein are methods of using such bacterial strains to degrade nitrite and/or TSNAs. | 09-18-2014 |
Mark T. Nielsen, Madison, TN US
Patent application number | Description | Published |
---|---|---|
20080209586 | NOVEL TOBACCO COMPOSITIONS AND METHODS OF MAKING - The present disclosure describes tobacco varieties having reduced levels of DVTs, methods of making such varieties, and tobacco compositions including such varieties. | 08-28-2008 |
20100307113 | Container Device for Tobacco Articles - Some embodiments of a tobacco product package device can be used to enhance freshness and other characteristics of tobacco products or other products contained therein. Certain features can improve product freshness both during shelf life and during consumer use. | 12-09-2010 |
Mark T. Nielsen, Nicholas, KY US
Patent application number | Description | Published |
---|---|---|
20100012137 | TOBACCO PLANTS HAVING REDUCED NICOTINE DEMETHYLASE ACTIVITY - The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof. | 01-21-2010 |
20100218270 | TOBACCO PLANTS HAVING A MUTATION IN A NICOTINE DEMETHYLASE GENE - The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. | 08-26-2010 |
20100235945 | NICOTIANA NUCLEIC ACID MOLECULES AND USES THEREOF - The present invention features | 09-16-2010 |
20100235952 | Nicotiana Nucleic Acid Molecules and Uses Thereof - The present invention features | 09-16-2010 |
Michael Hoeg Nielsen, Ellicott City, MD US
Patent application number | Description | Published |
---|---|---|
20090271039 | Method and apparatus for flue gas recirculation - An improved method and system for flue gas recirculation (FGR) from the ID Fan located downstream of a scrubber (or other Air Quality Control Equipment including cyclones, baghouses, etc., hereafter “AQC equipment”) back to the scrubber (or other AQC Equipment) inlet to maintain the minimum required flue gas throughput during low-load conditions, thereby eliminating the need for a separate booster fan. A flue gas recirculation duct is connected from downstream of the ID Fan to the inlet of the scrubber (or other AQC Equipment). A variable flow restrictor is placed in the duct downstream of the ID Fan for controlling pressure of the recirculated flue gas. The flow restrictor is controlled in accordance to a function of boiler load or flue gas flow to produce the required backpressure that enables the flue gas to flow through the recirculation duct back to the inlet of the scrubber (or other AQC Equipment) at low loads. This side stream of treated gas is recirculated from the discharge of the ID Fan to the inlet of the AQC Equipment to maintain the appropriate gas velocity regardless of boiler load conditions. The pressure differential between fan discharge and the AQC Equipment inlet enables recirculation of a sufficient amount of treated flue gas using only a small duct and simple flow control damper, without using a booster fan. | 10-29-2009 |
Montana Bach Nielsen, Bountiful, UT US
Patent application number | Description | Published |
---|---|---|
20120289117 | MODULAR FIGURINE AND ACCESSORY SYSTEM - The present disclosure provides various systems and methods for a customized modular figurine and accessory system having any number of components. A user may select from various possible components and accessories to assemble a unique and customized modular figurine using the artistic expression of the user. The customized modular figurine and accessory system may include a plurality of modular components, for example, a torso component, a head component, a wing component, and a skirt component, each of these individual components may then be selected by an individual to create and assemble a customized modular figurine. A support riser may extend into or through various components of an assembled customized modular figurine. A customizable display component may also be provided. | 11-15-2012 |
Nicholas Nielsen, Erie, CO US
Patent application number | Description | Published |
---|---|---|
20110231883 | METHODS AND APPARATUS FOR VARIABLE DELAY COMPENSATION IN NETWORKS - Methods and apparatus for performing dynamic compensation for delays over extant infrastructure within a content-based network. In one embodiment, the network comprises a cable network, and the infrastructure comprises that nominally used for on-demand (OD) services such as VOD. The method includes periodically or situationally assessing variable delays within the system associated with functional commands (such as “trick mode” commands), and dynamically compensating for these variable delays in order to improve the accuracy and timeliness of the user's trick mode command. This approach increases user satisfaction, and obviates the issuance of additional compensatory trick mode commands that only further degrade the performance of the network. | 09-22-2011 |
20140237524 | METHODS AND APPARATUS FOR VARIABLE DELAY COMPENSATION IN NETWORKS - Methods and apparatus for performing dynamic compensation for delays over extant infrastructure within a content-based network. In one embodiment, the network comprises a cable network, and the infrastructure comprises that nominally used for on-demand (OD) services such as VOD. The method includes periodically or situationally assessing variable delays within the system associated with functional commands (such as “trick mode” commands), and dynamically compensating for these variable delays in order to improve the accuracy and timeliness of the user's trick mode command. This approach increases user satisfaction, and obviates the issuance of additional compensatory trick mode commands that only further degrade the performance of the network. | 08-21-2014 |
Nicholas Martin Nielsen, Erie, CO US
Patent application number | Description | Published |
---|---|---|
20100199036 | SYSTEMS AND METHODS FOR BLOCK-LEVEL MANAGEMENT OF TIERED STORAGE - Acceleration of I/O access to data stored on large storage systems is achieved through multiple tiers of data storage. An array of first storage devices with relatively slow data access rates, such as hard disk drives, is provided along with a smaller number of second storage devices having relatively fast data access rates, such as solid state disks. Data is moved from the first storage devices to the second storage devices to improve data access time based on applications accessing the data and data access patterns. | 08-05-2010 |
Per E. Nielsen, Westlake, OH US
Patent application number | Description | Published |
---|---|---|
20100288944 | METHODS AND SYSTEMS FOR IN SITU PHYSICOCHEMICAL PROPERTY TESTING - An apparatus for evaluating physicochemical properties of sample materials contained in an array of vessels includes: a light detector; a light source for transmitting a light beam through the sample material in a vessel to the light detector; an analyzer for processing data from the light detector to determine concentration-related properties of the sample material as a function of time; and a mixing system. The mixing system includes: a plurality of magnetic stirrer elements, each for being placed in a sample material in a different one of the array of vessels; an array of magnetic drive elements, each associated with a different one of the array of vessels and being magnetically coupled with a magnetic stirrer element in an associated vessel; and a drive mechanism coupled to the array of magnetic drive elements for simultaneously moving each of the magnetic drive elements relative to an associated vessel. | 11-18-2010 |
Peter M. Nielsen, Chelsea, MA US
Patent application number | Description | Published |
---|---|---|
20090110380 | Underwater adaptive camera housing - An underwater camera housing provided with an adaptive mechanical control arrangement for use with a broad range of camera brands and models. The camera housing is preferably formed of front and rear housing sections that are molded of clear transparent plastic and arranged to be moved between an open position for mounting a camera within the housing and a closed position in which the housing provides a watertight enclosure for protecting and communicating with a camera. The housing is provided with a truncated hemispherical lens through which a camera views scenes to be photographed to reduce distortion and not foreshorten viewing angle and a flat window and optional diffuser for providing controlled artificial illumination to a scene. A mounting plate is structured to slideably fit into one of the housing halves in one of two lateral orientations and includes a slidably adjustable camera mounting plate that permits a user to securely and accurately position cameras side-to-side and for and aft with respect to truncated hemispherical lens. Push button assemblies adjustable in length and point of contact are used to permit a user to adapt them to interact with a variety of camera control actuator architectures. | 04-30-2009 |
Ralph Bendt Nielsen, Mclean, VA US
Patent application number | Description | Published |
---|---|---|
20110028774 | Hypernucleophilic Catalysts For Detoxification Of Chemical Threat Agents - A polymeric hypernucleophilic catalyst is effective for hydrolytic destruction of chemical threat agents under mild conditions, e.g., near neutral pH and at ambient temperatures. The polymeric hypernucleophilic catalysts are particularly useful to affect rapid destruction of chemical threat agents on sensitive surfaces such as paint, metal, rubber, plastic, fabric, wood, and skin. Catalyst formulations such as creams, lotions, sprays, foams, powders, or gels, and articles such as filters, wipes, membranes, yarns, fabrics, and articles of clothing, may be used for detoxification of or prophylactic protection against chemical threat agents. | 02-03-2011 |
Robert D. Nielsen, Lambertville, NJ US
Patent application number | Description | Published |
---|---|---|
20110095757 | Non-Destructive Determination of the Pore Size Distribution and The Distribution of Fluid Flow Velocities - A method is disclosed for the non-destructive determination of the pore size distribution and the distribution of fluid flow velocities using NMR spin echo signal measurements. In one embodiment, the invention involves simultaneously injecting acoustic energy ( | 04-28-2011 |
20140220638 | ALGAL MUTANTS HAVING A LOCKED-IN HIGH LIGHT ACCLIMATED PHENOTYPE - Mutant photosynthetic microorganisms having reduced chlorophyll and increased photosynthetic efficiency are provided. The mutants have a locked in high light-acclimated phenotype, in which many of the photosynthetic parameters characteristic of high light acclimated wild type cells are found in the LIHLA mutants when acclimated to low light, such as reduced chlorophyll, reduced NPQ, higher qP, higher E | 08-07-2014 |
Robert Louis Nielsen, Chapel Hill, NC US
Patent application number | Description | Published |
---|---|---|
20100293204 | RESOURCE NAME RECONCILIATION IN A CONFIGURATION DATABASE - A Configuration Management DataBase (CMDB) is utilized to reconcile names of enterprise computer resources in a Configuration Management Database (CMDB). Steps taken include creating a resource that belongs to a class that has multiple naming rules; in response to determining that more than one set of naming attributes is provided by the multiple naming rules, generating a set of valid names, in a priority order, for the resource; and correlating different names for the resource by, in accordance with the priority order, assigning one name for the resource to be a master name and assigning all other names for the resource to be alias names. | 11-18-2010 |
20100293205 | RESOURCE NAME RECONCILIATION IN A CONFIGURATION DATABASE - A Configuration Management DataBase (CMDB) is utilized to reconcile names of enterprise computer resources in a Configuration Management Database (CMDB). Steps taken include creating a resource that belongs to a class that has multiple naming rules; in response to determining that more than one set of naming attributes is provided by the multiple naming rules, generating a set of valid names, in a priority order, for the resource; and correlating different names for the resource by, in accordance with the priority order, assigning one name for the resource to be a master name and assigning all other names for the resource to be alias names. | 11-18-2010 |
Russell Nielsen, Boise, ID US
Patent application number | Description | Published |
---|---|---|
20080227293 | INTEGRATED CIRCUIT FABRICATION - A method for defining patterns in an integrated circuit comprises defining a plurality of features in a first photoresist layer using photolithography over a first region of a substrate. The method further comprises using pitch multiplication to produce at least two features in a lower masking layer for each feature in the photoresist layer. The features in the lower masking layer include looped ends. The method further comprises covering with a second photoresist layer a second region of the substrate including the looped ends in the lower masking layer. The method further comprises etching a pattern of trenches in the substrate through the features in the lower masking layer without etching in the second region. The trenches have a trench width. | 09-18-2008 |
20100317193 | INTEGRATED CIRCUIT FABRICATION - A method for defining patterns in an integrated circuit comprises defining a plurality of features in a first photoresist layer using photolithography over a first region of a substrate. The method further comprises using pitch multiplication to produce at least two features in a lower masking layer for each feature in the photoresist layer. The features in the lower masking layer include looped ends. The method further comprises covering with a second photoresist layer a second region of the substrate including the looped ends in the lower masking layer. The method further comprises etching a pattern of trenches in the substrate through the features in the lower masking layer without etching in the second region. The trenches have a trench width. | 12-16-2010 |
20120193777 | INTEGRATED CIRCUIT FABRICATION - A method for defining patterns in an integrated circuit comprises defining a plurality of features in a first photoresist layer using photolithography over a first region of a substrate. The method further comprises using pitch multiplication to produce at least two features in a lower masking layer for each feature in the photoresist layer. The features in the lower masking layer include looped ends. The method further comprises covering with a second photoresist layer a second region of the substrate including the looped ends in the lower masking layer. The method further comprises etching a pattern of trenches in the substrate through the features in the lower masking layer without etching in the second region. The trenches have a trench width. | 08-02-2012 |
20130320552 | INTEGRATED CIRCUIT FABRICATION - A method for defining patterns in an integrated circuit comprises defining a plurality of features in a first photoresist layer using photolithography over a first region of a substrate. The method further comprises using pitch multiplication to produce at least two features in a lower masking layer for each feature in the photoresist layer. The features in the lower masking layer include looped ends. The method further comprises covering with a second photoresist layer a second region of the substrate including the looped ends in the lower masking layer. The method further comprises etching a pattern of trenches in the substrate through the features in the lower masking layer without etching in the second region. The trenches have a trench width. | 12-05-2013 |
Simon L. Nielsen, Avoca, IA US
Patent application number | Description | Published |
---|---|---|
20090038564 | FAN DESIGN AND METHOD OF OPERATING - A method of cooling a radiator in an internal combustion engine wherein a plurality of fan assemblies is provided. Specifically, each fan assembly has a housing with an interior containing a fan blade and an exterior having six sides to form a hexagonal perimeter. The fan assemblies are then arranged side by side to form a cluster of fan assemblies in order to maximize the amount of fan assemblies that may be provided on an enclosure. The cluster of fan assemblies is then placed adjacent to a radiator to control the air flow over the radiator in order to cool the engine. | 02-12-2009 |
Steven F. Nielsen, Charlotte, NC US
Patent application number | Description | Published |
---|---|---|
20090183446 | MATERIAL AND METHOD FOR PROVIDING INSULATION AND DRAINAGE TO A FOUNDATION WALL - A material and method for insulating and providing a drainage path for a foundation wall includes a non-woven thermoplastic board being for insulating and providing a drainage path for a foundation wall. The non-woven thermoplastic board has a thermal resistance of an R-value per inch thickness of at least 1. The non-woven thermoplastic board also has a vertical drainage ability per inch thickness of at least 135 Gallons/Hour/Lineal-Foot/inch at a pressure of 500 pounds per square foot (psf). | 07-23-2009 |
20090200241 | REMOVAL OF OILS FROM SOLID SURFACES AND WATER WITH A SUBSTANCE HAVING A HIGH HUMATE LEVEL - The present invention relates to a method for removing oil from water or a solid surface. This involves contacting the water or the solid surface with a substance in the form of a sheet and having a high humate level under conditions effective for the substance to absorb oil from the water or the solid surface. The substance, having absorbed oil, is then recovered from the water or solid surface. In an alternative embodiment this method can be carried out where the substance is manure which may or may not be in the form of a sheet. | 08-13-2009 |
20090241453 | WATER VAPOR BARRIER FOR A CONCRETE FLOORING SYSTEM - A water vapor barrier material for a building structure includes a base entangled net material and a composite nonwoven. The composite nonwoven includes a film layer with a nonwoven layer on each side of the film layer. The film layer has a water vapor transmission rate of less than 10.0 g-MIL/100-in | 10-01-2009 |
20090242325 | ACOUSTICALLY INSULATING PRODUCT - An acoustically insulating product for acoustically insulating a building structure includes a base entangled net material, and an acoustical nonwoven material. The acoustical nonwoven material is on at least one side of the base entangled net material. The acoustical nonwoven material has an increase in impact insulation class of 6 or greater. | 10-01-2009 |
20110129649 | MATERIAL AND METHOD FOR PROVIDING INSULATION AND DRAINAGE TO A FOUNDATION WALL - A material and method for insulating and providing a drainage path for a foundation wall includes a non-woven thermoplastic board being for insulating and providing a drainage path for a foundation wall. The non-woven thermoplastic board has a thermal resistance of an R-value per inch thickness of at least 1. The non-woven thermoplastic board also has a vertical drainage ability per inch thickness of at least 135 Gallons/Hour/Lineal-Foot/inch at a pressure of 500 pounds per square foot (psf). | 06-02-2011 |
20110167999 | NONWOVEN CONSTRUCTION PRODUCT AND METHOD OF MAKING THE SAME - A protective armor product comprised of a panel which defines the interior and perimeter profile of the protective armor product. The panel is comprised of a stiff fibrous boardstock material with one or more layers of fibrous felted material of densified needlepunched construction. The fibrous felted material is comprised of a plurality of entangled polymeric fibers where at least a portion of the entangled polymeric fibers are melt fused together such that a plurality of fiber to fiber fusion bonding points are distributed within the fibrous felted material. The stiff fibrous boardstock material is formed into the panels to make the protective armor product. | 07-14-2011 |
20120064270 | FIBER-REINFORCED FILM PROCESSES AND FILMS - A blown-film process for making a fiber-reinforced film comprises providing and melting at least one thermoplastic resin. The at least one thermoplastic resin is extruded through an extension die to form a film bubble. A plurality of fibers is introduced inside of the film bubble. The fibers are distributed inside of the film bubble. The film bubble is collapsed after introducing the plurality of fibers so as to form a fiber-reinforced film. The fiber-reinforced film has a first thermoplastic layer, a second thermoplastic layer, and a plurality of fibers dispersed therebetween. The film may be formed in a bag. | 03-15-2012 |
20140090776 | FIBER-REINFORCED FILM PROCESSES AND FILMS - A blown-film process for making a fiber-reinforced film comprises providing and melting at least one thermoplastic resin. The at least one thermoplastic resin is extruded through an extension die to form a film bubble. A plurality of fibers is introduced inside of the film bubble. The fibers are distributed inside of the film bubble. The film bubble is collapsed after introducing the plurality of fibers so as to form a fiber-reinforced film. The fiber-reinforced film has a first thermoplastic layer, a second thermoplastic layer, and a plurality of fibers dispersed therebetween. The film may be formed in a bag. | 04-03-2014 |
20140370773 | INTERIOR PANEL FOR VEHICLE - An interior component for a vehicle may include a nonwoven fabric impregnated with a resin. The nonwoven fabric and resin are consolidated into a solid sheet devoid of pockets. The interior component may exclude metal coated filler particles and lubricants. The method of making the interior component includes the steps of: forming a nonwoven fabric of a staple fiber and a resin, consolidating the nonwoven fabric and the resin into a solid sheet, and forming the solid sheet into the vehicle component. The vehicle may be an airplane, train, subway car, light rail car, bus, or automobile. The resin may be a polymer selected from the group consisting of polyphenylene sulfide, polyetherimide, polyaryletherketone, co-polymers thereof, and combinations thereof. | 12-18-2014 |
Steven M. Nielsen, Hastings, MN US
Patent application number | Description | Published |
---|---|---|
20100007954 | RETROREFLECTIVE ARTICLES COMPRISING OLEFINIC SEAL FILMS - Microstructured articles, such as a retroreflective articles, having a plurality of (e.g. cube-corner) microstructured elements and a seal film layer adhered to portions of the cube-corner elements and/or portions of a (e.g., flexible) body layer. The seal film is a thermoplastic polymeric material comprising reaction products of alkylene in an amount of at least about 50% and reaction products of at least one non-acidic polar monomer. | 01-14-2010 |
Terence Nielsen, Spencerville, OH US
Patent application number | Description | Published |
---|---|---|
20090080976 | LIGHTWEIGHT AGGREGATE UNIT AND METHOD OF MANUFACTURE - A water channeling system includes at least one channeling member comprising fixed aggregate forming a solid body. In this embodiment, the at least one channeling member has a first end, a second end, and a plurality of fluidly connecting interstices therewithin. In this version, the at least one channeling member is water permeable longitudinally between the first end and the second end. The at least one channeling member may be installed below ground to channel water from a first location to a second location. The channeling member may be an elongate member or a vertical panel. The channeling member may comprise comprises polymeric aggregate particles having irregular shapes. The fixed aggregate may have a density of less than or equal to about 1 lb per cubic foot. Multiple channeling members may be placed end-to-end. | 03-26-2009 |
Terry Nielsen, Austin, TX US
Patent application number | Description | Published |
---|---|---|
20120258839 | AUXILIARY POWER UNIT HAVING A CONTINUOUSLY VARIABLE TRANSMISSION - Inventive embodiments are directed to components, subassemblies, systems, and/or methods for auxiliary power units (APU). In one embodiment, the APU includes a source of rotational power such as a combustion engine operably coupled to a continuously variable transmission (CVT). The CVT can be coupled to a load. In some embodiments, the load is provided by a generator. In one embodiment, the APU has a control system configured to control the operation of the engine and the operation of the CVT. The control system can facilitate substantially constant speed operation of the generator in the presence of variable operation of the engine. In another embodiment, the APU includes a continuously variable accessory drive (CVAD) operably coupled to an engine. The CVAD can include a continuously variable transmission operably coupled to a generator. In one embodiment, a skew-based control system is adapted to facilitate a change in the ratio of a CVAD. | 10-11-2012 |
Torben N. Nielsen, Monmouth Beach, NJ US
Patent application number | Description | Published |
---|---|---|
20100098406 | METHOD AND APPARATUS FOR INTERCONNECTING A PLURALITY OF OPTICAL TRANSDUCERS WITH A WAVELENGTH DIVISION MULTIPLEXED OPTICAL SWITCH - In a WDM optical communication system that includes a plurality of nodes interconnected by communication links, a node is provided that includes a first plurality of transponders each generating and/or receiving an information-bearing optical signal at a different channel wavelength from one another. An optical coupling arrangement, which may include one or more reconfigurable optical switches, transfers the channel wavelengths between a link connected to the node and the first plurality of transponders. The arrangement is adaptable to reconfigure its operational state to selectively direct different ones of the channel wavelengths from the link to different ones of the transponders without disturbing the optical path through the node traversed by any other channel wavelengths. A communications and configuration arrangement is provided, which transfers data identifying the respective channel wavelengths at which the transponders operate from the transponders to the optical coupling arrangement. In response to the transferred data, the communications and configuration arrangement reconfigures the operational state of the optical coupling arrangement. | 04-22-2010 |
Ulrik Nielsen, Quincy, MA US
Patent application number | Description | Published |
---|---|---|
20090291085 | ANTIBODIES AGAINST ERBB3 AND USES THEREOF - The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor. | 11-26-2009 |
20100056761 | ANTIBODIES AGAINST ERBB3 AND USES THEREOF - The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor. | 03-04-2010 |
20100266584 | ANTIBODIES AGAINST THE ECTODOMAIN OF ERBB3 AND USES THEREOF - The present invention provides a novel class of antibodies and antigen binding fragments thereof that bind the extracellular domain of ErbB3 receptor and inhibit various ErbB3 functions. For example, the antibodies and antigen binding fragments described herein are capable of binding to the receptor designated ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor. Such antibodies and antigen binding fragments thereof have the useful characteristic of inhibiting the proliferation of cancer cells expressing ErbB3. | 10-21-2010 |
20110027291 | METHODS, SYSTEMS AND PRODUCTS FOR PREDICTING RESPONSE OF TUMOR CELLS TO A THERAPEUTIC AGENT AND TREATING A PATIENT ACCORDING TO THE PREDICTED RESPONSE - The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided. | 02-03-2011 |
20110123523 | ANTIBODIES AGAINST ERBB3 AND USES THEREOF - The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor. | 05-26-2011 |
20110159513 | METHODS AND SYSTEMS FOR PREDICTING RESPONSE OF CELLS TO A THERAPEUTIC AGENT - The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided. | 06-30-2011 |
20110286976 | BI-SPECIFIC FUSION PROTEINS - Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair damaged tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to an ischemia-associated molecule; and (b) an activator domain that that detectably modulates the activity of a cellular network. | 11-24-2011 |
20110293579 | Bi-specific fusion proteins - Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to a target molecule; and (b) an activator domain that detectably modulates tissue regeneration. | 12-01-2011 |
20120244163 | BISPECIFIC BINDING AGENTS TARGETING IGF-1R AND ERBB3 SIGNALLING AND USES THEREOF - Disclosed are bispecific binding agents that specifically target both of the IGF-1 and the ErbB intracellular signaling pathways. For example, bispecific binding agents that comprise an anti-IGF-1R antibody and an anti-ErbB3 antibody connected by a linker are described herein. These bispecific agents are capable of antagonizing signal transduction by both of the IGF-1 and the ErbB signaling pathways and are useful in inhibiting the proliferation of tumor cells whose growth involves the signaling activity of both pathways. | 09-27-2012 |
20120308576 | MONOCLONAL AND OLIGOCLONAL ANTI-EGFR ANTIBODIES FOR USE IN THE TREATMENT OF TUMORS EXPRESSING PREDOMINANTLY HIGH AFFINITY EGFR LIGANDS OR TUMORS EXPRESSING PREDOMINANTLY LOW AFFINITY EGFR LIGANDS - Disclosed are pharmaceutical preparations for, and methods for determining, appropriate and effective treatment with therapeutic agents comprising a single species of anti-EGFR monoclonal antibody or therapeutic agents comprising a plurality of species of such antibodies, as well as kits useful for making such determinations. | 12-06-2012 |
20140127207 | ANTIBODIES AGAINST EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) AND USES THEREOF - Anti-EGFR antibodies, therapeutic compositions comprising combinations of anti-EGFR antibodies, as well as methods for using such antibodies and compositions to treat EGFR-related disorders (e.g., cancers), are disclosed. | 05-08-2014 |
20140127238 | METHODS, SYSTEMS AND PRODUCTS FOR PREDICTING RESPONSE OF TUMOR CELLS TO A THERAPEUTIC AGENT AND TREATING A PATIENT ACCORDING TO THE PREDICTED RESPONSE - The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided. | 05-08-2014 |
20140170668 | MONOCLONAL AND OLIGOCLONAL ANTI-EGFR ANTIBODIES FOR USE IN THE TREATMENT OF TUMORS EXPRESSING PREDOMINANTLY HIGH AFFINITY EGFR LIGANDS OR TUMORS EXPRESSING PREDOMINANTLY LOW AFFINITY EGFR LIGANDS - Disclosed are pharmaceutical preparations for, and methods for determining, appropriate and effective treatment with therapeutic agents comprising a single species of anti-EGFR monoclonal antibody or therapeutic agents comprising a plurality of species of such antibodies, as well as kits useful for making such determinations. | 06-19-2014 |
20140178380 | Bi-Specific Fusion Proteins - Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair damaged tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to an ischemia-associated molecule; and (b) an activator domain that that detectably modulates the activity of a cellular network. | 06-26-2014 |
20140234314 | ANTIBODIES AGAINST EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) AND USES THEREOF - Anti-EGFR antibodies, therapeutic compositions comprising combinations of anti-EGFR antibodies, as well as methods for using such antibodies and compositions to treat EGFR-related disorders (e.g., cancers), are disclosed. | 08-21-2014 |
20140234329 | ANTIBODIES AGAINST THE ECTODOMAIN OF ERBB3 AND USES THEREOF - The present invention provides a novel class of antibodies and antigen binding fragments thereof that bind the extracellular domain of ErbB3 receptor and inhibit various ErbB3 functions. For example, the antibodies and antigen binding fragments described herein are capable of binding to the receptor designated ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor. Such antibodies and antigen binding fragments thereof have the useful characteristic of inhibiting the proliferation of cancer cells expressing ErbB3. | 08-21-2014 |
Ulrik B. Nielsen, Quincy, MA US
Patent application number | Description | Published |
---|---|---|
20090246206 | BISPECIFIC BINDING AGENTS FOR MODULATING BIOLOGICAL ACTIVITY - Methods for improving the specific binding ability of bispecific binding compositions are described. The bispecific binding compositions are able to target cells by a high affinity targeting domain to a target cell surface marker and a low affinity binding domain that binds specifically to a second cell surface marker, wherein the binding of each domain to its respective cell surface marker increases or decreases, as desired, the biological activity of the respective cell surface markers. The invention further provides bispecific binding agents for use in the methods, as well as uses for the agents. | 10-01-2009 |
20120177652 | BISPECIFIC BINDING AGENTS FOR MODULATING BIOLOGICAL ACTIVITY - Methods for improving the biological and pharmaceutical properties of bispecific binding agents are described herein where the bispecific binding agents are able to target cells by a high affinity binding domain to a first cell surface marker that does not induce a significant biological effect and a low affinity binding domain that binds specifically to a second cell surface marker, causing a significant and desired biological effect. Compositions of such bispecific binding agents, uses for them, and kits containing them are also provided. | 07-12-2012 |
20130183311 | BISPECIFIC BINDING AGENTS FOR MODULATING BIOLOGICAL ACTIVITY - Methods for improving the biological and pharmaceutical properties of bispecific binding agents are described herein where the bispecific binding agents are able to target cells by a high affinity binding domain to a first cell surface marker that does not induce a significant biological effect and a low affinity binding domain that binds specifically to a second cell surface marker, causing a significant and desired biological effect. Compositions of such bispecific binding agents, uses for them, and kits containing them are also provided. | 07-18-2013 |
Vance G. Nielsen, Moorestown, NJ US
Patent application number | Description | Published |
---|---|---|
20120045518 | ENHANCING COAGULATION OR REDUCING FIBRINOLYSIS - Methods for controlling bleeding (e.g., enhancing coagulation and reducing fibrinolysis) in a subject are disclosed. The methods include selecting a subject in need of enhanced coagulation or reduced fibrinolysis, and administering to the subject a carbon monoxide releasing molecule (CORM). Examples of CORMs include tricarbonyldichloro-ruthenium (II) dimer, tricarbonylchloro-(glycinato)ruthenium (II), sodium boranocarbonate, dimanganese decacarbonyl, and iron pentacarbonyl. Further disclosed are compositions and methods for treating a subject in need of a blood product by administering to the subject a composition including a CORM and a blood product (e.g., cryoprecipitate or fresh frozen plasma). | 02-23-2012 |