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Nielsen, Lyngby

Carl Nielsen, Lyngby DK

Patent application numberDescriptionPublished
20090284934DATA ACQUISITION MODULE AND SYSTEM - The present invention relates to units or modules for data acquisition that may either be used as stand alone units or be used to form a modular system where a plurality of modules are mounted together in a frame or rack structure as well as combinations of such stand-alone units and frames. More specifically the invention relates to a module for data acquisition comprising a detachable front unit (11-19-2009

Hans Jorgen Nielsen, Lyngby DK

Patent application numberDescriptionPublished
20080261246TISSUE INHIBITOR OF MATRIX METALLOPROTEINASES TYPE-1 (TIMP-1) AS A CANCER MARKER AND POSTOPERATIVE MARKER FOR MINIMAL RESIDUAL DISEASE OR RECURRENT DISEASE IN PATIENTS WITH A PRIOR HISTORY OF CANCER - The present invention describes a method for determining whether an individual is suffering from cancer by determining a parameter representing the TIMP-1 concentration in body fluid samples from the individual. The present invention furthermore describes a method for determining whether an individual is suffering from minimal residual disease or recurrent cancer after being treated for the primary cancer by determining a parameter representing the post-operative TIMP-1 concentration in body fluid samples from the individual. In addition, the invention describes the additive effect of combined post-operative measurements of plasma TIMP-1 and serum CEA.10-23-2008
20090035794METHOD FOR DETECTING, SCREENING, AND/OR MONITORING CANCER IN AN INDIVIDUAL - The invention relates to a method for screening and/or detecting and/or monitoring a cancer in an individual, said method comprising determining a first parameter represented by the concentration of TIMP-1 in at least one excreta, e.g. saliva, from the individual. The invention provides a method that without the need to use a blood sample is suitable for facilitating the early diagnosis of a cancer, monitoring the recurrence of a cancer, and/or monitoring the status of a cancer or the effect of cancer treatment in an individual.02-05-2009

Patent applications by Hans Jorgen Nielsen, Lyngby DK

Hans Jørgen Nielsen, Lyngby DK

Patent application numberDescriptionPublished
20110060529TISSUE INHIBITOR OF MATRIX METALLOPROTEINASES TYPE-1 (TIMP-1) AS A CANCER MARKER - The present invention describes a method for determining whether an individual is likely to suffer from cancer by determining a parameter representing the TIMP-1 concentration in body fluid samples from the individual.03-10-2011

Jan Frank Nielsen, Lyngby DK

Lone Kierstein Nielsen, Lyngby DK

Patent application numberDescriptionPublished
20110212877DETERGENT COMPOSITION - Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.09-01-2011

Martin Dybendal Nielsen, Lyngby DK

Patent application numberDescriptionPublished
20090202204OPTICAL COUPLER, A METHOD OF ITS FABRICATION AND USE - The invention relates to: An optical coupler for coupling light from at least two input fibres into one output fibre. The invention further relates to a method of fabricating and to the use of an optical coupler. The object of the present invention is to provide an optical coupler, which is relatively easy to manufacture. The problem is solved in that the coupler comprises a) an input section comprising at least two input fibres, which are bundled over a bundling-length and having an output end face at one end of the bundling-length; and b) an output section comprising an output fibre comprising a confining region for confining light propagated in said input fibres and a surrounding cladding region and having an input end face;08-13-2009

Niels Fisker Nielsen, Lyngby DK

Patent application numberDescriptionPublished
20100216864RNA Antagonist Compounds for the Modulation of PCSK9 - The present invention provides compounds, compositions and methods for modulating the expression of PCSK9. In particular, this invention relates to oligomeric compounds, such as oligonucleotide compounds, which are hybridisable with target nucleic acids encoding PCSK9, and methods for the preparation of such oligomeric compounds. The oligonucleotide compounds have been shown to modulate the expression of PCSK9, and pharmaceutical preparations thereof and their use as treatment of hypercholesterolemia and related disorders are disclosed.08-26-2010
20110054011RNA Antagonist Compounds for the Modulation of FABP4/AP2 - Oligonucleotides directed against the FABP4 gene are developed for modulating the expression of FABP4 protein. The compositions comprise oligonucleotides, particularly antisense oligonucleotides, targeted to nucleic acids encoding FABP4. Methods of using these compounds for modulation of FABP4 expression and for the treatment of diseases associated with over expression of FABP4 are provided. Examples of such diseases are the metabolic syndrome, diabetes, atherosclerosis, and inflammatory states such as arthritis. The oligomer may be composed of deoxyribonucleosides or a nucleic acid analogue such as for example locked nucleic acid (LNA) or a combination thereof.03-03-2011