Nielsen, CA
Alex Nielsen, Stanford, CA US
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20100167370 | REDUCTION OF CARBON DIOXIDE EMISSION DURING ISOPRENE PRODUCTION BY FERMENTATION - The present invention provides methods for increasing the amount of isoprene produced by cultured cells with only a minimal increase in carbon dioxide emitted, thereby resulting in process having a greater yield of isoprene relative to carbon dioxide. In addition, the present invention provides compositions that include the cultured cells or isoprene produced there from. | 07-01-2010 |
Alex T. Nielsen, Stanford, CA US
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20110159557 | COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE - Provided herein are improved compositions and methods for the increased production of isoprene. Also provided herein are improved compositions and methods for the increased production of heterologous polypeptides capable of biological activity. | 06-30-2011 |
20110195472 | MEMBRANE BIOREACTOR FOR INCREASED PRODUCTION OF ISOPRENE GAS - The invention provides improved methods for the production of isoprene from biological materials. | 08-11-2011 |
Andreas K. Nielsen, Valley Center, CA US
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20080252188 | FURNITURE SYSTEM ENCLOSING ENTERTAINMENT ELECTRONICS IN RANGE OF WIDTHS - An entertainment center includes a base that expands horizontally to accommodate different width home theater displays; and, a light bridge that rests on top of one or more cabinets placed on either side of the base. The side cabinets provide a vertical column of open space for accommodating wiring among the entertainment system components and ventilation for heat generated by those components. The base includes casters to facilitate moving the base in and out from between the side cabinets. Sliding portions of the base extend horizontally yet continue to transfer all load weight onto the casters. The front woodwork of the base presents a pleasing seamless appearance as a consequence of overlapping trim pieces. | 10-16-2008 |
20080258589 | FURNITURE SYSTEM ENCLOSING ENTERTAINMENT ELECTRONICS IN RANGE OF WIDTHS - An entertainment center includes a base that expands horizontally to accommodate different width home theater displays; and, a light bridge that rests on top of one or more cabinets placed on either side of the base. The side cabinets provide a vertical column of open space for accommodating wiring among the entertainment system components and ventilation for heat generated by those components. The base includes casters to facilitate moving the base in and out from between the side cabinets. Sliding portions of the base extend horizontally yet continue to transfer all load weight onto the casters. The front woodwork of the base presents a pleasing seamless appearance as a consequence of overlapping trim pieces. | 10-23-2008 |
20080258595 | FURNITURE SYSTEM ENCLOSING ENTERTAINMENT ELECTRONICS IN RANGE OF WIDTHS - An entertainment center includes a base that expands horizontally to accommodate different width home theater displays; and, a light bridge that rests on top of one or more cabinets placed on either side of the base. The side cabinets provide a vertical column of open space for accommodating wiring among the entertainment system components and ventilation for heat generated by those components. The base includes casters to facilitate moving the base in and out from between the side cabinets. Sliding portions of the base extend horizontally yet continue to transfer all load weight onto the casters. The front woodwork of the base presents a pleasing seamless appearance as a consequence of overlapping trim pieces. | 10-23-2008 |
Andrew Nielsen, Santa Clara, CA US
Patent application number | Description | Published |
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20110173215 | RETRIEVAL SYSTEM, RETRIEVAL SPACE MAP SERVER APPARATUS AND PROGRAM - To provide a retrieval space map in which the ratio of unnecessary files included in the retrieval result can be decreased. One or more retrieval object spaces (retrieval objects) in which a file suitable for a retrieval purpose exists at high possibility are predefined according to the retrieval purpose under a condition containing a number of retrieval objects, and the space in which a necessary file exists at high possibility can be searched by designating the retrieval object to be suited for the retrieval purpose at the time of retrieval. | 07-14-2011 |
20140346217 | MULTI-PAGE PRESENTATION AND STORAGE FOLDER AND METHOD OF USE - A multi-page presentation folder is described that is capable of securing and displaying one or more sheets of material, such as sheets of music. One or more sheets may be secured and displayed via each panel of the multi-page presentation folder. In various embodiments, for a given number of page turns, a greater number of sheets may be displayed and/or presented. For example, in one embodiment, a multi-page presentation folder allows user to “turn a page” only once to view up to six sheets or only twice to view up to eight sheets. The folder may also provide stability to the sheets of material preventing them from sagging. | 11-27-2014 |
Benjamin E. Nielsen, Sunnyvale, CA US
Patent application number | Description | Published |
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20150347776 | METHODS AND SYSTEM FOR IMPLEMENTING A SECURE LOCK SCREEN - Disclosed herein is a technique for implementing a secure lock screen on a computing device. The secure lock screen is configured to permit particular applications to display their content—such as main user interfaces (UIs)—while maintaining a desired overall level of security on the computing device. Graphics contexts, which represent drawing destinations associated with the applications, are tagged with entitlement information that indicates whether or not each graphics context should be displayed on the computing device when the computing device is in a locked-mode. Specifically, an application manager tags each application that is initialized, where the tagging is based on a level of entitlement possessed by the application. In turn, a rendering server that manages the graphics contexts can identify the tagged entitlement information and display or suppress the content of the applications in accordance with their entitlements. | 12-03-2015 |
Bruce S. Nielsen, Diamond Springs, CA US
Patent application number | Description | Published |
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20150013249 | Door Jamb Security Fixture - A door jamb assembly with improved aesthetics and security includes a strike plate and at least one bolt hole in the strike plate that engages a bolt. The assembly further includes a door jamb and a recessed portion on a stud side of the door jamb. The recessed portion is dimensioned to provide clearance for the strike plate so that the strike plate is substantially disposed within the door jamb when the door jamb abuts a stud. | 01-15-2015 |
Bryan Joseph Nielsen, San Diego, CA US
Patent application number | Description | Published |
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20090303698 | ILLUMINATED HELMET - The present invention provides an illuminated helmet with a plurality of lamps positioned in at least one recess in the helmet to reduce the risk of damage to the lamps and prevent the lamps from injuring a user during an accident. The illuminated helmet also provides specific recesses for the lamps and other components located in a non-impact area of the helmet to further reduce the risk of injury from the components and lamps in an accident. Furthermore, the illuminated helmet provides a proximity sensor mounted within the helmet that lacks mechanical parts and automatically activates the lamps when the helmet is worn by a user, improving the safety and reliability of the proximity sensor and overall helmet. The lamps are arranged in such a manner as to be visible to a viewer from any angle, and the flashing patterns of the lamps are uniquely programmed to draw the attention of the human eye. | 12-10-2009 |
Cameron James Nielsen, San Diego, CA US
Patent application number | Description | Published |
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20120016345 | LUER CONNECTOR - A luer lock connector is disclosed. The luer lock connector includes a connector body having a distal end, a proximal end, and a gripping portion between the distal end and the proximal end. A substantially flexible material is disposed on at least the outer surface of the gripping portion of the connector body. An intravenous line is coupled to the distal end of the connector body. A luer connector fitting is disposed on the proximal end of the body, the luer connector having an outer diameter less than a maximum exterior thickness of the gripping portion of the connector body. | 01-19-2012 |
Curtis W. Nielsen, Carlsbad, CA US
Patent application number | Description | Published |
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20130054023 | Asynchronous Data Stream Framework - An architecture comprising a hardware layer, a data collection layer and an execution layer lays the foundation for a behavioral layer that can asynchronously access abstracted data. A plurality of data sensors asynchronously collect data which is thereafter abstracted so as to be usable by one or more behavioral modules simultaneously. Each of the behaviors can be asynchronously executed as well as dynamically modified based on the collected abstracted data. Moreover, the behavior modules themselves are structured in a hierarchical manner among one or more layers such that outputs of behavior module associated with a lower layer may be the input to a behavior module of a higher letter. Conflicts between outputs of behavior modules are arbitrated and analyzed so as to conform with an overall mission objective. | 02-28-2013 |
20130054024 | Universal Payload Abstraction - Robotic payloads are abstracted to provide a plug-and-play system in which mission specific capabilities are easily configured on a wide variety of robotic platforms. A robotic payload architecture is presented in which robotic functionalities are bifurcated into intrinsic capabilities, managed by a core module, and mission specific capabilities, addressed by mission payload module(s). By doing so the core modules manages a particular robotic platform's intrinsic functionalities while mission specific tasks are left to mission payloads. A mission specific robotic configuration can be compiled by adding multiple mission payload modules to the same platform managed by the same core module. In each case the mission payload module communicates with the core module for information about the platform on which it is being associated. | 02-28-2013 |
20140035725 | Distributed Positioning and Collaborative Behavior Determination - A system and its associated methodology for distributed positioning and collaborative behavioral determination among a group of objects, interactive tags associated with each of a plurality of objects provide to each object relative positional data and state information regarding the other nearby objects. Using this information, each object develops a spatial awareness of its environment, including the position and action of nearby objects so as to, when necessary, modify its behavior to more effectively achieve an objective. | 02-06-2014 |
20140049429 | Collaborative Spatial Positioning - Disparate positional data derived from one or more positional determinative resources are fused with peer-to-peer relational data to provide an object with a collaborative positional awareness. An object collects positional determinative information from one or more positional resources so to independently determine its spatial location. That determination is thereafter augmented by peer-to-peer relational information that can be used to enhance positional determination and modify behavioral outcomes. | 02-20-2014 |
20140052293 | Conflict Resolution Based on Object Behavioral Determination and Collaborative Relative Positioning - Using distributed positioning, collaborative behavioral determination, and probabilistic conflict resolution objects can independently identify and resolve potential conflicts before the occur. In one embodiment of the invention, interactive tags and other sensor resources associated with each of a plurality of objects provide among the objects relative positional data and state information. Using this information each object develops a spatial awareness of its environment, including the positional and action of nearby objects so as to, when necessary, modify its behavior to more effectively achieve an objective and resolve potential conflicts. | 02-20-2014 |
David Nielsen, Alameda, CA US
Patent application number | Description | Published |
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20090271160 | Composite assets for use in multiple simulation environments - One of a plurality of description elements for a scenario is attached to a composite asset. The composite asset comprises one or more data sets. Each data set is associated with a simulation. And, a simulation asset is generated for a scenario based at least in part on the composite asset. | 10-29-2009 |
Douglas A. Nielsen, San Diego, CA US
Patent application number | Description | Published |
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20090231580 | BEAM STEERING ELEMENT AND ASSOCIATED METHODS FOR MANIFOLD FIBEROPTIC SWITCHES AND MONITORING - An optical system comprising a combination optical switch and monitoring system based on an array of mirrors, and a moveable reflective element co-packaged together, including discrete sets of fiber ports wherein λn from input fiber ports is focused on λn mirror via the use of shared free space optics; such as shared beam steering elements, dispersive elements, and optical elements, and discrete arrays of MEMS mirrors utilized to select and switch selected wavelengths from the input fiber port(s) to an output fiber port(s) of the optical switch, and wherein a moveable reflective element sharing the same free space optics is utilized to sweep across and reflect selected portions of the optical spectrum back to a photodetector. By correlating reflective element position with power measured, a processor can obtain a spectral plot of the wavelength band of interest, as well as calculate parameters such as center wavelength, passband shape, and OSNR. | 09-17-2009 |
Douglas Soren Nielsen, Placentia, CA US
Patent application number | Description | Published |
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20150252602 | LOCKING HINGE WITH SPHERICAL BEARING ASSEMBLIES - The present disclosure includes a hinge assembly for use in a hinged attachment of a panel relative to a frame and providing movement of the panel relative to the frame. A link which provides an extension or reach motion and positioning of the assembly, shown for purposes of illustration and not limitation in the form of a gooseneck arm, is provided in the hinge assembly to facilitate an extended range of motion of the hinge assembly. A first spherical bearing assembly and a second spherical bearing assembly are operatively associated with a bearing end of the link to provide multiple degrees of motion while securely retaining the panel relative to the frame. The hinge is intended to provide universal application of a single version of a hinge which can be used in multiple locations as facilitated by the multiple degrees of motion provided by the bearing end of the link | 09-10-2015 |
Edward S. Nielsen, Castaic, CA US
Patent application number | Description | Published |
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20080255438 | SYSTEM FOR MONITORING PHYSIOLOGICAL CHARACTERISTICS - Apparatuses and methods for medical monitoring physiological characteristic values such as blood glucose levels for the treatment of diabetes, are presented. The apparatuses and methods provide for preventing any negative consequence in the operation of a monitor and/or infusion device as a result of disorientation that may occur from waking from slumber with a low blood glucose level. In addition, a graphical display is disclosed incorporating a variety of enhancements which readily conveys to the user historical as well as real time information regarding the measured characteristic value. | 10-16-2008 |
Elizabeth Leigh Nielsen, Santa Monica, CA US
Patent application number | Description | Published |
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20150324434 | User-Trained Searching Application System and Method - System, apparatus, user equipment, and associated computer program and computing methods are provided for suggesting websites that are relevant based on the user's browsing history and past search results. In one aspect, a hosted computer application stores the user's browsing history and search results using a cloud-based storage facility, and computing methods, using machine learning techniques, are operative to predict websites the user may want to visit next. Example machine learning techniques may be configured to use non-parsed and unstructured data to identify patterns and map hundreds of thousands of data elements, to predict which website(s) the user might like to visit in a search/browsing session. Example machine learning techniques may be further operative to recognize patterns and analyze data at each interaction with the user. The training of example machine learning techniques is driven by user interaction, allowing the removal of non-relevant or less relevant websites from the suggested websites via a suitable user interface. | 11-12-2015 |
Engward William Nielsen, El Cajon, CA US
Patent application number | Description | Published |
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20120156005 | BUFFER AIR FOR A LABYRINTH SEAL - A method of providing buffer air to a labyrinth seal includes operating a multi-stage compressor system having an earlier stage and a later stage such that the air pressure at the later stage is higher than the air pressure at the earlier stage. The method may further include selectively directing compressed air from one of the earlier stage or the later stage to the seal based on a parameter indicative of air pressure within the compressor system. | 06-21-2012 |
20130214492 | GAS TURBINE ENGINE LUBRICATION FLUID BARRIER - A system for forming a barrier between a lubrication oil region and an air region of a gas turbine engine comprising a lubrication oil return path, a centrifugal oil slinger on a rotating member fixed to a spool of the gas turbine engine, a spiral groove configured to directs lubrication oil toward an oil return path, a labyrinth seal, and a cavity configured to form a non-contacting seal with the spiral groove and the labyrinth seal. | 08-22-2013 |
20140064946 | GAS TURBINE ENGINE COMPRESSOR UNDERCUT SPACER - A gas turbine engine compressor spacer ( | 03-06-2014 |
Eric H. Nielsen, Santa Cruz, CA US
Patent application number | Description | Published |
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20130124807 | Enhanced Software Application Platform - A system includes information for generating a first appliance based on first appliance information, information for generating a second appliance based on second appliance information, and information for configuring communication between the first appliance and the second appliance. The system further includes at least one processor configured to generate a first volume by copying the first appliance information using a first set of parameters associated with an environment in which the first volume is situated, and generate a second volume by copying the second appliance information using a second set of parameters associated with an environment in which the second volume is situated. The system also includes at least one processor configured to initiate a first appliance instance by executing code from the first volume using information in the third volume, and initiate a second appliance instance by executing code in the second volume using information in a fourth volume. | 05-16-2013 |
20150268881 | Enhanced Software Application Platform - A system includes information for generating a first appliance based on first appliance information, information for generating a second appliance based on second appliance information, and information for configuring communication between the first appliance and the second appliance. The system further includes at least one processor configured to generate a first volume by copying the first appliance information using a first set of parameters associated with an environment in which the first volume is situated, and generate a second volume by copying the second appliance information using a second set of parameters associated with an environment in which the second volume is situated. The system also includes at least one processor configured to initiate a first appliance instance by executing code from the first volume using information in the third volume, and initiate a second appliance instance by executing code in the second volume using information in a fourth volume. | 09-24-2015 |
Henrik K. Nielsen, San Jose, CA US
Patent application number | Description | Published |
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20080225275 | Detection system for nanometer scale topographic measurements of reflective surfaces - A linear position array detector system is provided which imparts light energy to a surface of a specimen, such as a semiconductor wafer, receives light energy from the specimen surface and monitors deviation of the retro or reflected beam from that expected to map the contours on the specimen surface. The retro beam will, with ideal optical alignment, return along the same path as the incident beam if and only if the surface is normal to the beam. The system has a measurement device or sensor within the path of the retro or reflected beam to measure deviation of the retro beam from expected. The sensor is preferably a multiple element array of detector-diodes aligned in a linear fashion. A unique weighting and summing scheme is provided which increases the mechanical dynamic range while preserving sensitivity. The system further includes a bright field Nomarski Differential Interference Contrast sensor used to split the beam into two beams and for scanning in an orientation orthogonal to the orientation of the optical lever created by the system. | 09-18-2008 |
20090067137 | High Density In-Package Microelectronic Amplifier - A sensor module having a package substrate, a sensor disposed within and electrically connected to the package substrate, an amplifier disposed within and electrically connected to the package substrate, and electrical traces within the package substrate for routing sensor signals from the sensor to the amplifier, and then from the amplifier to external electrical connectors on the package substrate. | 03-12-2009 |
Holly H. Nielsen, San Jose, CA US
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20140156103 | AUTOMATICALLY MANAGING THE ENVIRONMENT OF A PHYSICAL ZONE - A system, method, and computer program product for automatically managing an environment for a physical zone over a period of time. Position coordinates are received from a plurality of entities. It is determined which of the entities will occupy the physical zone over a time frame, the physical zone including at least one environmental characteristic. Environmental preferences are accessed for the entities determined to occupy the physical zone for the time frame. The environmental characteristic of the physical zone is adjusted for the time frame based on the accessed environmental preferences for the entities. | 06-05-2014 |
Holly L. Nielsen, San Jose, CA US
Patent application number | Description | Published |
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20150127665 | Personalized Quantitative Measure of Accessibility - A mechanism is provided in a data processing system for personalized quantitative measure of accessibility. For a given web site or web application, the mechanism accesses existing crowd sourced user ratings. The mechanism generates a crowd source score for the given web site or web application based on the crowd sourced user ratings. The mechanism generates a compliance score for the given web site or web application based on compliance data published for the given web site or web application. The mechanism obtains a static analysis score for the given web site or web application. The mechanism generates weights for a given user based on user profile information of the given user and applies the weights to the crowd source score, the compliance score, and the static analysis score to form weighted data. The mechanism generates a personalized accessibility score based on the weighted data. | 05-07-2015 |
James Nielsen, San Francisco, CA US
Patent application number | Description | Published |
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20090036923 | Systems and methods for accommodating anatomical characteristics in the treatment of septal defects - Systems and methods for treating internal tissue defects, such as septal defects, with implantable devices are provided. An exemplary clip-based device includes a tubular body having at least a deflectable anchors coupled thereto. The anchors can be coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each anchor extends outwardly away from the tubular body in a position configured to abut a tissue surface. The anchors are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall. Also provided are delivery devices for delivering the implantable closure device and methods for using the various devices. | 02-05-2009 |
20100234854 | Systems and Methods for Treating Septal Defects with Capture Devices and Other Devices - Systems, devices and methods for treating internal tissue defects, such as septal defects, are provided. An exemplary method of treating an internal tissue defect, specifically a method of closing a patent foramen ovale (PFO), can include passing a closure element from a right atrium through a septal wall in a first location and into the left atrium. A capture device, which can be configured as a snare-like device, can be used to capture the closure element in the left atrium and pull the closure element back through the septal wall in a different, second location, such that the closure element is routed over the PFO. The closure element can then be anchored and/or locked against the septal wall such that the PFO is at least partially closed. | 09-16-2010 |
20110208213 | Systems and Methods for Treating Septal Defects with Capture Devices and Other Devices - Systems, devices and methods for treating internal tissue defects, such as septal defects, are provided. An exemplary method of treating an internal tissue defect, specifically a method of closing a patent foramen ovale (PFO), can include passing a closure element from a right atrium through a septal wall in a first location and into the left atrium. A capture device, which can be configured as a snare-like device, can be used to capture the closure element in the left atrium and pull the closure element back through the septal wall in a different, second location, such that the closure element is routed over the PFO. The closure element can then be anchored and/or locked against the septal wall such that the PFO is at least partially closed. | 08-25-2011 |
20110245849 | Systems and Methods for Accommodating Anatomical Characteristics in the Treatment of Septal Defects - Systems and methods for treating internal tissue defects, such as septal defects, with implantable devices are provided. An exemplary clip-based device includes a tubular body having at least a deflectable anchors coupled thereto. The anchors can be coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each anchor extends outwardly away from the tubular body in a position configured to abut a tissue surface. The anchors are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall. Also provided are delivery devices for delivering the implantable closure device and methods for using the various devices. | 10-06-2011 |
20120046688 | Clip-Based Systems and Methods for Treating Septal Defects - Systems and methods for treating internal tissue defects, such as septal defects, with clip-based devices are provided. An exemplary clip-based device includes a tubular body having at least a first and a second deflectable member coupled thereto. The first and second members are coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each member extends outwardly away from the tubular body in a position configured to abut a tissue surface. The first and second members are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall. | 02-23-2012 |
20120245599 | Systems and Methods for Treating Septal Defects with Capture Devices and Other Devices - Systems, devices and methods for treating internal tissue defects, such as septal defects, are provided. An exemplary method of treating an internal tissue defect, specifically a method of closing a patent foramen ovale (PFO), can include passing a closure element from a right atrium through a septal wall in a first location and into the left atrium. A capture device, which can be configured as a snare-like device, can be used to capture the closure element in the left atrium and pull the closure element back through the septal wall in a different, second location, such that the closure element is routed over the PFO. The closure element can then be anchored and/or locked against the septal wall such that the PFO is at least partially closed. | 09-27-2012 |
James T. Nielsen, San Francisco, CA US
Patent application number | Description | Published |
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20090259126 | METHODS AND DEVICES FOR DELIVERING INJECTIONS - Device and method are provided for diagnosing and treating diseases and injuries to the spine by injecting drugs into the diseased or injured area. The device and method of the subject invention provide improvements to patient and operator safety, along with ease-of-use and convenience improvements over conventional techniques. | 10-15-2009 |
20100069934 | Anastomosis Method Utilizing Tool with Fluid-Driven Actuator - A method of performing anastomosis between a graft vessel and a target vessel, each having a circumferential wall and a lumen therethrough, may include providing an anastomosis tool including a tissue effector and a fluid-driven actuator operationally connected to that tissue effector; connecting the fluid-driven actuator to an energy source; placing an end of the graft vessel in proximity to the side of the target vessel; and actuating the fluid-driven actuator to connect the end of the graft vessel to the side of the target vessel. | 03-18-2010 |
20100155453 | Surgical Staples Frangibly Connected to Staple Holding Strip - A surgical tool may include a staple holding strip, and surgical staples frangibly connected to an edge of that staple holding strip. | 06-24-2010 |
20110101069 | Surgical Stapler with Direct Sled to Staple Contact - An exemplary surgical stapler may include a staple holder, staples positioned within the staple holder, and at least one structure slidable within the staple holder to contact directly at least one staple, where that direct contact deploys at least one staple from the staple holder. Another exemplary surgical stapler may include a staple holder, an anvil movably connected to the staple holder, staples positioned within the staple holder; and a sled slidable within the staple holder to contact directly at least one staple, where that direct contact urges at least one staple out of the staple holder and against the anvil. | 05-05-2011 |
20120004595 | DEVICES AND METHODS FOR CUTTING AND EVACUATING TISSUE - Various medical devices and methods for cutting and/or evacuating tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy or discectomy. | 01-05-2012 |
20120283742 | DEVICES AND METHODS FOR CUTTING TISSUE - Various medical devices and methods for cutting and/or evacuating tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy or discectomy. | 11-08-2012 |
20130046199 | DEVICES AND METHODS FOR CUTTING TISSUE - Various medical devices and methods for cutting and/or evacuating tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy or discectomy. | 02-21-2013 |
20130211321 | DEVICES AND METHODS FOR RESECTING SOFT TISSUE - The present devices and methods relate generally to medical devices and methods for cutting, resecting, excising and/or evacuating tissue from various regions of a patient's body. In particular, devices and methods for cutting and/or removing various tissues, e.g., polyps or endometrium, from a uterus or uterine space are provided. Devices and methods for cutting and/or removing various tissues from the human body, such as during laparoscopic or thoracoscopic surgery, are also provided. | 08-15-2013 |
20130211438 | DEVICES AND METHODS FOR CUTTING TISSUE - Various medical devices and methods for cutting, evacuating and/or performing work on tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy. | 08-15-2013 |
20130218186 | VACUUM POWERED ROTARY DEVICES AND METHODS - The present devices and methods relate generally to vacuum or suction powered medical devices and methods for cutting, resecting, excising, morcellating and/or evacuating tissue from various regions of a patient's body, in certain variations, the devices may produce a rotational motion by converting a linear reciprocating motion to a rotational motion, causing a cutting shaft or other tool to rotate to perform work on a tissue in various regions of the body. | 08-22-2013 |
20130310834 | DEVICES AND METHODS FOR CUTTING TISSUE - Various medical devices and methods for cutting, evacuating and/or performing work on tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy. | 11-21-2013 |
20140081266 | DEVICES AND METHODS FOR CUTTING TISSUE - Various medical devices and methods for cutting, evacuating and/or performing work on tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy. | 03-20-2014 |
20150150580 | DEVICES AND METHODS FOR CUTTING TISSUE - Various medical devices and methods for cutting, evacuating and/or performing work on tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy. | 06-04-2015 |
20150201995 | VACUUM POWERED ROTARY DEVICES AND METHODS - The present devices and methods relate generally to vacuum or suction powered medical devices and methods for cutting, resecting, excising, morcellating and/or evacuating tissue from various regions of a patient's body. In certain variations, the devices may produce a rotational motion by converting a linear reciprocating motion to a rotational motion, causing a cutting shaft or other tool to rotate to perform work on a tissue in various regions of the body. | 07-23-2015 |
Jeffery Nielsen, Simi Valley, CA US
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20100325687 | Systems and Methods for Custom Device Automatic Password Management - In various embodiments, a method comprises receiving a custom login script from a first user, receiving a custom change password script from the first user, logging onto an account on a digital device using the custom login script from the first user, changing an old password on the account to a new password at predetermined intervals using the custom change password script from the first user, receiving a password request from a second user, approving the password request, and checking out the new password to the second user. | 12-23-2010 |
20100325705 | Systems and Methods for A2A and A2DB Security Using Program Authentication Factors - In various embodiments, security may be provided for application to application (A2A) and application to database (A2DB) implementations. In some embodiments, a method comprises receiving a registration request at a first digital device for a first application, receiving a first program factor associated with the first application, confirming the first program factor, generating a first password for a second application based, at least, on the confirmation of the first program factor, and providing the first password to a second digital. | 12-23-2010 |
20100325707 | Systems and Methods for Automatic Discovery of Systems and Accounts - In various embodiments, a method comprises scanning a directory structure to generate a scan result comprising a plurality of discovered systems, identifying one or more accounts associated with at least one of the plurality of discovered systems, configuring a security appliance to change one or more old passwords to one or more new passwords for the one or more accounts, and changing, with the configured security appliance, the one or more old passwords to the one or more new passwords. | 12-23-2010 |
Jens Mitchell Nielsen, San Francisco, CA US
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20150070821 | COVER, ELECTRONIC DEVICE THEREWITH AND METHOD FOR MANUFACTURING THE SAME - A cover adapted to an electronic device is disclosed. The electronic device includes a casing and the cover includes a first covering member and a second covering member. The first covering member is made of first transparent material. The second covering member is adjacent to the first covering member. The second covering member is made of second transparent material, and at least one fine feature is formed on the second covering member. | 03-12-2015 |
Jessica Nielsen, Le Verne, CA US
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20130019813 | Burrow Filling Compressed Growing Medium - A growing medium for use in plugging pest orifices includes a bulking agent and a water-retentive polymer blended together and compressed at a volume-to-volume ratio greater than 3:1, wherein the growing medium is at least 50% superabsorbing polymer. | 01-24-2013 |
Jonathan Nielsen, Aliso Viejo, CA US
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20140052149 | HIP REPLACEMENT NAVIGATION SYSTEM AND METHOD - In another embodiment, a hip joint navigation jig is provided that includes an anatomical interface comprising a bone engagement portion. A registration jig is also provided that is coupled, e.g., removeably, with the anatomical interface. A rotatable member is provided for rotation about an axis that is not vertical when the jig is mounted to the bone adjacent to a hip joint and the registration jig is coupled with the anatomical interface. An anatomy engaging probe is coupled with the rotatable member for rotation about the axis and is translatable to enable the probe to be brought into contact with a plurality of anatomical landmarks during a procedure. An inertial sensor is coupled with the probe to indicate orientation related to the landmarks, the sensor being disposed in a different orientation relative to horizontal when the probe is in contact with the landmarks. | 02-20-2014 |
20150127009 | DEVICES AND METHODS FOR KNEE ARTHROPLASTY - The present invention provides, in certain embodiments, a device for positioning and orienting the femoral cutting block. The present invention also provides a device for setting rotation of sagittal resection for unicompartmental knee arthroplasty. The present invention further provides methods for setting the rotation of the tibial implant by kinematic measurements. | 05-07-2015 |
20150150569 | DEVICES AND METHODS FOR INTRA-OPERATIVE SPINAL ALIGNMENT - The present invention provides a spinal alignment system comprising at least one vertebral coupler, at least one reference device and a surgical orientation device. The present invention further provides methods using the spinal alignment system to assist in alignment of the spine during a surgical procedure to correct a deformity due to trauma or degeneration. The present invention also provides a pedicle screw navigation system comprising of a pedicle screw navigator, a first reference device, a second reference device and a surgical orientation device. The present invention provides methods using the pedicle screw navigation system to assist in determining the proper orientation of a pedicle screw during spinal surgery. | 06-04-2015 |
Jonathan Kirk Nielsen, Dana Point, CA US
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20100332194 | IMPLANT TRAINING SYSTEM - An implant training system based on a biomechanical modeling system is disclosed. In one embodiment, the implant training system includes a processor configured to load and execute instructions from an implant simulation module and the implant simulation module configured to provide a preloaded case representing a model patient to a user, receive input from the user to adjust the preloaded case to represent a particular patient, and provide outcome information for using an implant in the particular patient. | 12-30-2010 |
20110190898 | CRUCIATE-RETAINING KNEE PROSTHESIS - Certain embodiments generally provide an improved tibial base member comprising keel portions that allow one or both cruciate ligaments to be preserved. Other embodiments provide improved lateral and/or medial inserts having a mesial lip that helps relieve and/or prevent impingement between the femoral component and the tibial eminence. Other embodiments provide improved femoral components having various chamfers to provide additional clearance with respect to the tibial eminence and posterior cruciate ligament without decreasing bone coverage. | 08-04-2011 |
20130331945 | ANATOMICAL MOTION HINGED PROSTHESIS - A hinged knee prosthesis comprises a tibial component and a femoral component. The tibial component is configured to attach to a tibia. The tibial component has a bearing surface. The femoral component is configured to hingedly attach to the tibial component and rotate relative to the tibial component. The femoral component comprises a medial condyle and a lateral condyle. The medial and lateral condyles have an eccentric sagittal curvature surface configured to rotate and translate on the bearing surface of the tibial component. A method of rotating a hinged knee through a range of flexion is provided. The method fixedly attaches a femoral component to a tibial component. Axial rotation of the femoral component is induced relative to the tibial component when the hinged knee is flexed. | 12-12-2013 |
20150088265 | CRUCIATE-RETAINING KNEE PROSTHESIS - Certain embodiments generally provide an improved tibial base member comprising keel portions that allow one or both cruciate ligaments to be preserved. Other embodiments provide improved lateral and/or medial inserts having a mesial lip that helps relieve and/or prevent impingement between the femoral component and the tibial eminence. Other embodiments provide improved femoral components having various chamfers to provide additional clearance with respect to the tibial eminence and posterior cruciate ligament without decreasing bone coverage. | 03-26-2015 |
Jon F. Nielsen, Los Angeles, CA US
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20090002851 | Sub-Micron Adjustable Mount for Supporting a Component and Method - An optical assembly includes a light path and at least one optic to be positioned in the path. A support arrangement supports the optic having a foot arrangement including at least one foot that receives a direct manipulation with the foot slidingly engaged against a support surface to move the optic relative to the light path. Movement of the foot may move the optic along a predetermined path. The foot defines a footprint for engaging the support surface and receives the direct manipulation in a way which changes the footprint on the support surface to move the optic responsive to changes in the footprint. A movement arrangement may selectively bias the foot against the support surface during a movement mode, intended to permit movement of the foot against the support surface, and in a locked mode, intended to lock the foot against the support surface. | 01-01-2009 |
20100118421 | Sub-Micron Adjustable Mount for Supporting a Component and Method - An optical assembly includes a light path and at least one optic to be positioned in the path. A support arrangement supports the optic having a foot arrangement including at least one foot that receives a direct manipulation with the foot slidingly engaged against a support surface to move the optic relative to the light path. Movement of the foot may move the optic along a predetermined path. The foot defines a footprint for engaging the support surface and receives the direct manipulation in a way which changes the footprint on the support surface to move the optic responsive to changes in the footprint. A movement arrangement may selectively bias the foot against the support surface during a movement mode, intended to permit movement of the foot against the support surface, and in a locked mode, intended to lock the foot against the support surface. | 05-13-2010 |
Justin O. Nielsen, Redondo Beach, CA US
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20110169438 | METHOD AND SYSTEM FOR CONTROLLING AN ELECTRIC MOTOR USING ZERO CURRENT OFFSET VALUE CANCELLATION - Methods and systems for controlling an electric motor are provided. The electric motor includes at least one winding. A winding current flowing through the at least one winding is monitored. The winding current has an oscillating component and an offset component. The offset component of the winding current is isolated from the oscillating component of the winding current. The electric motor is controlled based on the offset component of the winding current. | 07-14-2011 |
Kirk G. Nielsen, Newport Beach, CA US
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20100121307 | Microneedles, Microneedle Arrays, Methods for Making, and Transdermal and/or Intradermal Applications - Embodiments are directed to microneedle array devices for intradermal and/or transdermal interaction with the body of patient to provide therapeutic, diagnostic or preventative treatment wherein portions of the devices may be formed by multi-layer, multi-material electrochemical fabrication methods and wherein individual microneedles may include valve elements or other elements for controlling interaction (e.g. fluid flow). In some embodiments needles are retractable and extendable from a surface of the device. In some embodiments, interaction occurs automatically with movement across the skin of the patient while in other embodiments interaction is controlled by an operator (e.g. doctor, nurse, technician, or patient). | 05-13-2010 |
Kyle P. Nielsen, Diamond Springs, CA US
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20150013249 | Door Jamb Security Fixture - A door jamb assembly with improved aesthetics and security includes a strike plate and at least one bolt hole in the strike plate that engages a bolt. The assembly further includes a door jamb and a recessed portion on a stud side of the door jamb. The recessed portion is dimensioned to provide clearance for the strike plate so that the strike plate is substantially disposed within the door jamb when the door jamb abuts a stud. | 01-15-2015 |
Lars Fjeldsoe Nielsen, San Francisco, CA US
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20140087709 | ASSOCIATING A PARTICULAR ACCOUNT CONFIGURATION DURING THE OUT OF BOX EXPERIENCE FOR A MOBILE DEVICE - A method of providing particular account configurations to a user of a mobile device based on a predetermined account configuration offering between a mobile device manufacturer and a third-party service provider based on a code stored on the mobile device. During the out-of-box experience (OOBE) when the user is initially configuring the mobile device, the third-party provider receives user information, a code, and a mobile device identification number. The third-party service provider confirms that the mobile device is eligible for the particular account configuration by using the code and mobile device identification number. Once account configuration eligibility is confirmed, the third-party service provider associates the particular account configuration with either an existing user account or with a new user account established during the OOBE. | 03-27-2014 |
20140370874 | ASSOCIATING A PARTICULAR ACCOUNT CONFIGURATION DURING THE OUT OF BOX EXPERIENCE FOR A MOBILE DEVICE - A method of providing particular account configurations to a user of a mobile device based on a predetermined account configuration offering between a mobile device manufacturer and a third-party service provider based on a code stored on the mobile device. During the out-of-box experience (OOBE) when the user is initially configuring the mobile device, the third-party provider receives user information, a code, and a mobile device identification number. The third-party service provider confirms that the mobile device is eligible for the particular account configuration by using the code and mobile device identification number. Once account configuration eligibility is confirmed, the third-party service provider associates the particular account configuration with either an existing user account or with a new user account established during the OOBE. | 12-18-2014 |
Laurence E. Nielsen, Escondido, CA US
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20080312861 | CALIBRATION PROCESS MANAGEMENT SYSTEM AND DATA STRUCTURE - A method for calibration process management of a calibration testing unit and a plurality of units under test, comprising configuring a user interface in communication with a calibration process management software system, configuring a communications link in communication with the software system, the software system capable of communicating with the calibration testing unit and the plurality of units under test, wherein the software system manages the user interface and the communications link in a manner permitting an operator to calibrate the plurality of units under test. Tracking of the calibrated units under test uses a permanent unique identifier and a dynamic unique identifier. | 12-18-2008 |
Mark Nielsen, San Juan Capistrano, CA US
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20130045713 | Text Message Authentication System - Systems and method for authenticating users are presented. A system can send a passkey to a user interface of a known device. A user can then send a messaging service message with the passkey from a second device to the system. After receiving the message from the user, the system can extract the passkey from the message, and compare the received passkey against the passkey originally sent to the user. The known device and the second device can each have separate and unique device identifiers. | 02-21-2013 |
20150113615 | TEXT MESSAGE AUTHENTICATION SYSTEM - Systems and method for authenticating users are presented. A system can send a passkey to a user interface of a known device. A user can then send a messaging service message with the passkey from a second device to the system. After receiving the message from the user, the system can extract the passkey from the message, and compare the received passkey against the passkey originally sent to the user. The known device and the second device can each have separate and unique device identifiers. | 04-23-2015 |
Mary Nielsen, Palo Alto, CA US
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20080267524 | AUTOMATIC IMAGE ENHANCEMENT - This invention provides a method for automated image enhancement. Attribute measurements are extracted from a digital image and used for the generation of at least a noise threshold parameter, a sharpness parameter and a radicality parameter. The noise threshold parameter and sharpness parameter are evaluated to determine the degree of noise reduction and the degree of sharpening to be performed, collectively a determined enhancement. The determined enhancement is applied to derive a nominally enhanced image. With respect to the radicality parameter, the output image is the weighted average between the initial image and the nominally enhanced image. | 10-30-2008 |
Michael Scott Nielsen, San Francisco, CA US
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20120023116 | SYSTEM AND METHOD FOR CONVERSION OF JMS MESSAGE DATA INTO DATABASE TRANSACTIONS FOR APPLICATION TO MULTIPLE HETEROGENEOUS DATABASES - A system and method for performing real-time conversion of data which is present in the form of messages on JMS-compliant or other messaging systems into database transactions, which can then subsequently be applied to multiple heterogeneous databases or other systems. In accordance with an embodiment, the invention provides a means by which data can be read from messages in a messaging system, and converted to a set of database operations that are then stored as a persistent trail file (for example, as an Oracle GoldenGate trail file). The operations, as recorded in the trail file, can then be routed via a network and applied to target systems as required, for example to maintain a replicated set of information at one or more different or heterogeneous systems. The data in the message can be formatted in a variety of ways, for example, as fixed width, delimited, or XML data, and the system can be configured to convert this data as appropriate. In accordance with an embodiment, the data can be read in real-time from the messaging system, and written out as quickly as it can be consumed to the persistent trail files. In scenarios where there is no current means of integration of two systems, the invention can be used as a bridge if, for example, the source system is modified or configured to write data changes to a messaging system, and Oracle GoldenGate is used as a means of delivery to the target system. | 01-26-2012 |
20140172886 | SYSTEM AND METHOD FOR CONVERSION OF JMS MESSAGE DATA INTO DATABASE TRANSACTIONS FOR APPLICATION TO MULTIPLE HETEROGENEOUS DATABASES - A system and method for performing real-time conversion of data which is present in the form of messages on JMS-compliant or other messaging systems into database transactions; which can then subsequently be applied to multiple heterogeneous databases or other systems. In accordance with an embodiment, the invention provides a means by which data can be read from messages in a messaging system, and converted to a set of database operations that are then stored as a persistent trail file. The operations can then be routed via a network and applied to target systems as required, for example to maintain a replicated set of information at one or more different or heterogeneous systems. The data in the message can be formatted in a variety of ways, for example, as fixed width, delimited, or XML data, and the system can be configured to convert this data as appropriate. | 06-19-2014 |
Nerissa Nielsen, Kingsburg, CA US
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20140205569 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING OSTEOARTHRITIS - The invention provides methods for preventing and treating osteoarthritis, preventing and treating the degradation of articular cartilage, and promoting and maintaining joint health in an animal. The methods comprise administering DGLA to the animals, preferably in amounts of from about 0.01 to about 100 mg/kg/day. | 07-24-2014 |
Nierissa Nielsen, Kingsburg, CA US
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20140205569 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING OSTEOARTHRITIS - The invention provides methods for preventing and treating osteoarthritis, preventing and treating the degradation of articular cartilage, and promoting and maintaining joint health in an animal. The methods comprise administering DGLA to the animals, preferably in amounts of from about 0.01 to about 100 mg/kg/day. | 07-24-2014 |
Per Nielsen, Chula Vista, CA US
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20090286520 | SYSTEM, METHOD, AND APPARATUS FOR INCREASING A LIKELIHOOD OF ADVERTISEMENT DISPLAY - Aspects include methods, systems, and apparatuses for increasing a likelihood of advertisement display. The method may include receiving advertisement information comprising a presentation schedule and indicia indicating the first advertisement; determining, based upon the advertisement information, whether the first advertisement is located on a mobile device; retrieving the first advertisement from a remote device and storing it on a storage module on the mobile device if the first advertisement is determined to not be located on the mobile device; and rendering the first advertisement on the mobile device. The method may also include receiving advertisement information comprising a retrieval schedule and retrieving the first advertisement from a remote device by reference to the retrieval schedule. Other methods and apparatuses include determining and broadcasting advertisement information. | 11-19-2009 |
20150244689 | METHODS AND APPARATUS FOR PROTECTED DISTRIBUTION OF APPLICATIONS AND MEDIA CONTENT - Methods, devices, apparatus, computer-readable media and processors are provided that protect the distribution of media content. Media content is encrypted and the associated cryptographic mechanisms are stored and accessible either remotely at a networked database or internally within a data storage device memory. Access to the cryptographic mechanisms is granted by associating the cryptographic mechanisms with a data storage device identification and, optionally, a computing device identification. | 08-27-2015 |
Per O. Nielsen, Chula Vista, CA US
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20100122189 | SYSTEM AND METHOD OF PROVIDING INTERACTIVE ADVERTISEMENTS - Apparatus and methods for providing content by presenting multimedia content on a mobile device; receiving, on the mobile device, indicia of at least one insertion point in the multimedia content; receiving, on the mobile device, at least one identifier associated with the at least one insertion point, the identifier identifying one or more executable content; and presenting the executable content to a user of the mobile device proximate to the at least one insertion point. | 05-13-2010 |
20100262336 | SYSTEM AND METHOD FOR GENERATING AND RENDERING MULTIMEDIA DATA INCLUDING ENVIRONMENTAL METADATA - A system and method for generating and rendering multimedia data including environmental data is disclosed. In one embodiment, a system for rendering content in a vehicle is disclosed, the system comprising a receiver configure to receive, via a wireless broadcast, audiovisual content and an environmental event associated with a subset of the audiovisual content and a vehicular electronic system configured to render the audiovisual content and alter an environmental parameter in accordance with the environmental event when the associated subset of the audiovisual content is rendered. | 10-14-2010 |
20110126094 | METHOD OF MODIFYING COMMANDS ON A TOUCH SCREEN USER INTERFACE - A method of modifying commands is disclosed and may include detecting an initial command gesture and determining whether a first subsequent command gesture is detected. Further, the method may include executing a base command when a first subsequent command gesture is not detected and executing a first modified command when a first subsequent command gesture is detected. | 05-26-2011 |
20130342573 | Transitioning 3D Space Information to Screen Aligned Information for Video See Through Augmented Reality - Methods, apparatuses, and systems are provided to transition 3D space information detected in an Augmented Reality (AR) view of a mobile device to screen aligned information on the mobile device. In at least one implementation, a method includes determining augmentation information associated with an object of interest, including a Modelview (M1) matrix and a Projection (P1) matrix, displaying the augmentation information on top of a video image of the object of interest using the M1 and P1 matrices, generating a second Modelview (M2) matrix and a second Projection (P2) matrix, such that the matrices M2 and P2 represent the screen aligned final position of the augmentation information, and displaying the augmentation information using the M2 and P2 matrices. | 12-26-2013 |
20140028712 | Method and apparatus for controlling augmented reality - Method and apparatus for controlling an augmented reality interface are disclosed. In one embodiment, a method for use with an augmented reality enabled device (ARD) comprises receiving image data for tracking a plurality of objects, identifying an object to be selected from the plurality of objects, determining whether the object has been selected based at least in part on a set of selection criteria, and causing an augmentation to be rendered with the object if it is determined that the object has been selected. | 01-30-2014 |
20140028713 | Interactions of Tangible and Augmented Reality Objects - Method, computer program product, and apparatus for providing interactions of tangible and augmented reality objects are disclosed. In one embodiment, a method for use with an augmented reality enabled device (ARD) comprises performing 3-dimensional tracking of one or more objects based at least in part on captured images of the one or more objects, detecting a state change of at least one object of the one or more objects based at least in part on the captured images, and causing an augmentation to be rendered in response to the state change of the at least one object, where a type of the augmentation is based at least in part on the state change of the at least one object. | 01-30-2014 |
20140028714 | Maintaining Continuity of Augmentations - Methods and apparatuses for maintaining continuity of augmentations are disclosed. In one embodiment, a method for use with an augmented reality enabled device (ARD) comprises tracking a plurality of objects and a background based at least in part on visual information derived from an image, maintaining states of the plurality of objects based at least in part on information other than the visual information, and providing data for rendering augmentation in response to the states of the plurality of objects. | 01-30-2014 |
20140028850 | Augmentation of Tangible Objects as User Interface Controller - Method, computer program product, and apparatus for providing interactions of tangible and augmented reality objects are disclosed. In one embodiment, a method of controlling a real object using a device having a camera comprises receiving a selection of at least one object, tracking the at least one object in a plurality of images captured by the camera, and causing control signals to be transmitted from the device to the real object via a machine interface based at least in part on the tracking. | 01-30-2014 |
Per O. Nielsen, Chulas Vista, CA US
Per O. Nielsen, San Diego, CA US
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20110090255 | CONTENT BOUNDARY SIGNALING TECHNIQUES - Methods and devices provide a user interface that provides visual cues when a document pan or scroll has reached an end or boundary by distorting the document image in response to further user inputs. The image distortion functionality may include shrinking, stretching, accordion expansion, or bouncing of a document image. The degree of image distortion may be proportional to the distance that a user input would have the document move beyond the encountered boundary. When a boundary of a document image is reached during a rapid pan or scroll, a bouncing image distortion may be applied to the document image to inform the user that the document reached a boundary during the movement. | 04-21-2011 |
20110166932 | SYSTEM AND METHOD OF PROVIDING CONTENT BASED ON USER INTERACTION - Methods and systems provide for displaying advertisement items on mobile devices in response to user selections. Advertisement items may be transmitted to mobile devices ahead of an insertion point and stored in memory. While displaying a content item, mobile devices may display a list of alternatives related advertisement content and prompt the user to select one. Mobile devices may determine an advertisement content item to display at the insertion point based on a received user input or lack of an input. In a further embodiment, mobile devices report displayed advertisement items to a service, such as the distributor, content provider, or a third party. In a further embodiment, the selection of alternative advertisement items to present to the user is made based upon weighting values associated with each advertisement item. Such weighting values may be adjusted when advertisement items are displayed or listed in a user interface display. | 07-07-2011 |
20130222312 | CONTENT BOUNDARY SIGNALING TECHNIQUES - Methods and devices provide a user interface that provides visual cues when a document pan or scroll has reached an end or boundary by distorting the document image in response to further user inputs. The image distortion functionality may include shrinking, stretching, accordion expansion, or bouncing of a document image. The degree of image distortion may be proportional to the distance that a user input would have the document move beyond the encountered boundary. When a boundary of a document image is reached during a rapid pan or scroll, a bouncing image distortion may be applied to the document image to inform the user that the document reached a boundary during the movement. | 08-29-2013 |
20140192210 | MOBILE DEVICE BASED TEXT DETECTION AND TRACKING - Embodiments disclosed pertain to mobile device based text detection and tracking. In some embodiments, a first reference frame is obtained by performing Optical Character Recognition (OCR) on an image frame captured by a camera to locate and recognize a first text block. A subsequent image frame may be selected from a set of subsequent image frames based on parameters associated with the selected subsequent image and a second reference frame may be obtained by performing OCR on the selected subsequent image frame to recognize a second text block. A geometric relationship between the first and second text blocks is determined based on a position of the first text block in the second reference frame and a pose associated with the second reference frame. | 07-10-2014 |
Per Orum Nielsen, San Diego, CA US
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20140285522 | SYSTEM AND METHOD FOR PRESENTING TRUE PRODUCT DIMENSIONS WITHIN AN AUGMENTED REAL-WORLD SETTING - Methods, systems, computer-readable media, and apparatuses for presenting a representation of an augmented real-world setting are presented. In some embodiments, a method includes presenting a representation of an augmented real-world setting. The method includes capturing a plurality of images of a real-world setting. The method also includes analyzing one or more real-world objects within the plurality of images of the real-world setting. The method further includes receiving information pertaining to a real-world product, wherein the information is indicative of first physical dimensions of the real-world product during a first mode of operation and second physical dimensions of the real-world product during a second mode of operation and overlaying an augmented reality object depicting the real-world product during the first mode of operation, and having the first physical dimensions, within at least one of the plurality of images of the real-world setting, based at least in part on the analyzing step. | 09-25-2014 |
20150062166 | EXPANDING A DIGITAL REPRESENTATION OF A PHYSICAL PLANE - Techniques are presented for expanding a digital representation of a physical plane from a physical scene. In some aspects, a method may include determining an orientation and an initial portion of a physical plane in the scene, and subdividing a rectified image for the scene into a plurality of grid cells. For the grid cells, an image signature may be generated. A grid cell contiguous to the obtained initial portion of the plane is determined to include part of the plane. An iterative process may be performed for each neighboring grid cell from the grid cell contiguous to at least part of the obtained initial portion, determining whether the neighboring grid cell is to be included as part of the plane if the image signature of said neighboring grid cell is similar to the image signature of a grid cell already determined to be included as part of the plane. | 03-05-2015 |
Richard Nielsen, Laguna Niguel, CA US
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20100111784 | Configurations And Methods For Carbon Dioxide And Hydrogen Production From Gasification Streams - A syngas treatment plant is configured to remove sulfurous compounds and carbon dioxide from shifted or un-shifted syngas in a configuration having a decarbonization section and a desulfurization section. Most preferably, the solvent in the decarbonization section is regenerated and cooled by flashing, while the solvent is regenerated in the desulfurization section via stripping using external heat, and it is still further preferred that carbonylsulfide is removed in the desulfurization section via hydrolysis, and that the so produced hydrogen sulfide is removed in a downstream absorber. | 05-06-2010 |
Richard B. Nielsen, Laguna Niguel, CA US
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20100011810 | NGL Recovery Methods and Configurations - Contemplated plants and methods for NGL recovery from feed gases having a carbon dioxide content equal or greater than about 2% employ temperature control configurations that allow high-level and flexible recovery of ethane and heavier components while avoiding freezing of the carbon dioxide in the process. Where the feed gas has a significant fraction of C3+ components and moderate carbon dioxide content, a single column configuration with an intermediate reflux condenser may be used, while two-column configurations may be used for feed gases with high carbon dioxide content and relatively low C3+ component concentration. | 01-21-2010 |
20100043488 | NGL Recovery Methods and Configurations - Contemplated NGL plants include a feed gas bypass circuit through which a portion of the feed gas is provided downstream to a vapor portion of the feed gas to thereby increase turbo expander inlet temperature and demethanizer temperature. Contemplated configurations are especially advantageous for feed gases with relatively high carbon dioxide content as they entirely avoid carbon dioxide freezing in the demethanizer, provide additional power production by the turboexpander, and recover C2+ components to levels of at least 80% while achieving a low carbon dioxide content in the NGL product. | 02-25-2010 |
20100135880 | Hydrocarbon Based Sulfur Solvent Systems and Methods - Contemplated configurations and methods for elemental sulfur removal from various gases, and especially well acid gases employ a hydrocarbon solvent that dissolves the sulfur to form a rich solvent and that is then regenerated by hydrotreating. Thus, sulfur is removed from the rich solvent as H2S that may then be processed (e.g., in Claus unit or absorption unit) while the regenerated solvent is routed back to the well and associated production pipes. | 06-03-2010 |
20120186788 | LOW-ENERGY WASTE GAS COOLING USING DIRECT CONTACT CONDENSER - Heat is removed from a process liquid of a direct contact condenser in waste gas cooling using two separate and distinct cooling devices that provide cooled process liquid to at least two separate sections in the direct contact condenser. Most preferably, the sections are liquidly isolated and provide the heated process liquids to the respective cooling devices. However, in other embodiments, the sections are liquidly coupled to each other so to allow transfer of the process liquid from one section to another section. One of the two cooling devices uses a lower-cost or higher-availability coolant that the other. It is generally preferred that one of the cooling devices is an air cooler and that another one of the cooling devices employs a cooling medium other than air. | 07-26-2012 |
Richard Ove Nielsen, Anaheim, CA US
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20090257314 | ACOUSTIC WIDE AREA AIR SURVEILLANCE SYSTEM - A method and apparatus for detecting an aircraft. The method is provided for wide area tracking of aircraft. An acoustic emission of the aircraft is detected from a plurality of locations. A position of the aircraft at a set of times is estimated by comparing a set of harmonically related Doppler shifted frequencies for the acoustic emission to an expected zero Doppler shifted frequency of the aircraft to form an estimated position. The position of the aircraft and a heading of the aircraft are tracked using the estimated position. The aircraft type is classified based on the corresponding set of zero Doppler frequencies at each acoustic sensor. | 10-15-2009 |
Robert Nielsen, Pasadena, CA US
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20150203974 | CATALYTIC PLATFORM FOR CO2 REDUCTION - Carbon dioxide reduction includes bonding CO | 07-23-2015 |
Robert D. Nielsen, Cupertino, CA US
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20120278808 | PEER TO PEER COMPONENT DISTRIBUTION - A method, apparatus, and system are provided for assigning tasks and/or providing resources in a distributed system. An indication of a task being available for processing is provided to one or more remote systems in a distributed system based on a distribution list. At least one response from one of the remote systems capable of performing the task is received in response to the indication. The response includes a request for a resource for performing the task. The resource for performing the task is provided to the remote systems. | 11-01-2012 |
Robert David Nielsen, Palo Alto, CA US
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20110307902 | ASSIGNING TASKS IN A DISTRIBUTED SYSTEM - A method and apparatus are provided for assigning tasks in a distributed system. The method comprises indicating to one or more remote systems in the distributed system that a task is available for processing based on a list identifying the one or more remote systems. The method further comprises receiving at least one response from the one or more remote systems capable of performing the task based on the indication. The method comprises allowing at least one of the remote systems to perform the task based on the at least one received response. | 12-15-2011 |
Simon Nielsen, El Segundo, CA US
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20130174439 | Diffuser - A diffuser for use with a hair dryer has a body that fits over the outlet of the hair dryer. The diffuser has one or more diffusing features, namely excess mesh, a non-symmetrical rotor, a perforated plate, and diffusion projections extending toward a discharge opening of the diffuser, each projection having a bore with a side orifice for directing air output by the hair dryer radially. | 07-11-2013 |
Simon S. Nielsen, El Segundo, CA US
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20110079058 | Locking Top for Container - A locking apparatus for containers, vials and bottles comprises a combination lock to be applied to a generic bottle or vial or for a custom bottle. The locking apparatus comprises a locking subassembly: a housing, a collapsible portion on the housing or on a separate washer piece, at least one indicia ring, at least one tumbler key ring, and a setting plug; the locking subassembly will engage a first bracket, which can be mounted on a generic bottle or vial or to a custom bottle with a top end, which has a integrated bracket end. | 04-07-2011 |
Suzanne M. Nielsen, San Clemente, CA US
Patent application number | Description | Published |
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20110106181 | ADJUSTABLE SADDLE FOR A BONE ANCHOR - A bone anchor is provided, which may be used in cervical, thoracic, lumbar or sacral areas of the spine or other orthopedic locations. The anchor includes an anchoring portion, a receiving portion, and an internal saddle that is rotatable with respect to the receiving portion at least to a degree. The anchoring portion is attachable to a bone. A rod or other elongated support member is received in the receiving portion in contact with the saddle. The rod and saddle may be rotated for variability substantially in a plane, and an engaging member is engaged to the receiving portion to lock the rod within the receiving portion. | 05-05-2011 |
Sven Nielsen, San Diego, CA US
Patent application number | Description | Published |
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20090249000 | Method and system for error correction of a storage media - A data file on a storage media is processed during playback or execution to identify unreadable data. Replacement data corresponding to the unreadable data is obtained over a communications network, and the replacement data is used to playback or execute the data file as if the data file does not contain any unreadable data. | 10-01-2009 |
20120210168 | METHOD AND SYSTEM FOR ERROR CORRECTION OF A STORAGE MEDIA - A data file on a storage media is processed during playback or execution to identify unreadable data. Replacement data corresponding to the unreadable data is obtained over a communications network, and the replacement data is used to playback or execute the data file as if the data file does not contain any unreadable data. | 08-16-2012 |
Sven E. Nielsen, San Diego, CA US
Patent application number | Description | Published |
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20090234912 | FILE TRANSFER VIA LOCAL SERVER - Embodiments of the present invention use a web browser on a client and a file transfer server to transfer files over a wide-area network (WAN). The files are transferred from the client to the server or vice versa. The server transfers the file to a remote server via the WAN. Because the file transfer over the WAN is server-based, the client can handle its end of the file transfer process using a conventional web browser without special file transfer software. | 09-17-2009 |
20130031214 | METHOD AND SYSTEM FOR EFFICIENT DOWNLOAD OF DATA PACKAGE - Methods for efficient download of a data package and a client device and server that may implement such methods are disclosed. The client device sends an inventory identifying existing stored content packages to the download server. The download server identifies portions of the requested data package already corresponding to content elements already stored on the client device, and sends information to the client device indicating which portions of the requested data package are already stored on the client device. The client device gathers the already-stored portions of the requested data package and requests a remaining portion of the requested data package from the download server. The download server receives the request for the remaining portion of the requested data package and sends the remaining portion to the client device. | 01-31-2013 |
Thomas A. Nielsen, Newark, CA US
Patent application number | Description | Published |
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20110307351 | MICRO-PAYMENT SYSTEM ARCHITECTURE - A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers. | 12-15-2011 |
Thomas A. Nielsen, San Francisco, CA US
Patent application number | Description | Published |
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20120130855 | MICRO-PAYMENT SYSTEM ARCHITECTURE - A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers. | 05-24-2012 |
20130006812 | MICRO-PAYMENT SYSTEM ARCHITECTURE - A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers. | 01-03-2013 |
Thomas Kurt Nielsen, Oceanside, CA US
Patent application number | Description | Published |
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20080246485 | Compact underwater electromagnetic measurement system - An underwater EM measurement system, which is substantially smaller, much simpler to use, and more robust than prior systems, is formed as a sensor package integrated into a single pressure vessel includes two magnetic sensors including induction coils disposed substantially horizontally so as to measure fields in orthogonal directions. The package also includes two electric field sensors including electric potential antennas adapted to couple to a water potential via a capacitive electrode having a conducting material and an electrically insulative layer formed of an insulating material. The capacitive electrode has a capacitance to the medium of greater than 1 mF. Preferably, the insulating material is a metal oxide. | 10-09-2008 |
20100245120 | SEA VESSEL TAGGING APPARATUS AND SYSTEM - The present invention discloses a tagging and identification device and system for tracking and monitoring sea vessels as they enter sea ports, estuaries and/or other channels. The tagging device of the present invention comprises a receiver, for receiving an underwater electromagnetic signal transmitted by an underwater beacon. An acoustic transmitter is provided for transmitting an identification signal to an acoustic receiver deployed nearby. The acoustic identification signal is transmitted after an electromagnetic trigger signal is received from the underwater beacon. The tagging and device may further comprise a memory device which can store data relating to position and time of the see vessel to which it is attached. The tagging and identification device of the present invention is covert, compact and is capable of extended active deployment without replenishment of batteries etc. The identification tagging device and system of the present invention is capable of being deployed for tracking the location of sea vessels without the knowledge of the vessel crew. The system of the present invention allows third a third party to monitor suspect vessels as they enter specific ports or estuaries. | 09-30-2010 |
Tom Nielsen, Newark, CA US
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20120272176 | Persistent User Interface for Providing Navigational Functionality - A method and apparatus, including a graphical user interface, for allowing quick processing of queries, including display of results, without requiring opening of a traditional browser program application window. Queries may be input and processed directly from a persistent or otherwise on-demand query input area, without the need to open a browser or other program separately for entering/processing a query, navigating to a search engine or particular document, etc. A number of query types may be supported by the user interface of the present invention, such that depending on a particular query type selected for/indicated by a query, a particular information retrieval mechanism processes the query to obtain one or more results. An on-demand result window is generated in response to a query request to output one or more results obtained in response to a given query. | 10-25-2012 |
William Nielsen, San Jose, CA US
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20110126911 | Composite Plastic Articles - This invention provides composite plastic articles and methods of making them. The articles can be fluidic or microfluidic devices having fluidic conduits and, optionally, pneumatic conduits that regulate flow in the fluidic conduits. The articles comprise a first substrate coated with a layer of a material that comprises, or onto which have been introduced, reactive groups. For example, the substrate can be a plastic coated with an oxide or a siloxane onto which hydroxyl groups have been introduced. These articles are covalently bonded with other articles comprising reactive groups on their surfaces, for example, polysiloxanes treated to have silanol groups. Certain articles have specified locations on their surfaces that are not bonded to the other piece. For example, the coating can be removed from these locations before bonding. Such locations can be useful as functional elements of various devices, such as valve seats in valves of microfluidic devices. | 06-02-2011 |
William D. Nielsen, Livermore, CA US
Patent application number | Description | Published |
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20110039303 | MICROFLUIDIC AND NANOFLUIDIC DEVICES, SYSTEMS, AND APPLICATIONS - The present invention discloses the integration of programmable microfluidic circuits to achieve practical applications to process biochemical and chemical reactions and to integrate these reactions. In some embodiments workflows for biochemical reactions or chemical workflows are combined. Microvalves such as programmable microfluidic circuit with Y valves and flow through valves are disclosed. In some embodiments microvalves of the present invention are used for mixing fluids, which may be part of an integrated process. These processes include mixing samples and moving reactions to an edge or reservoir for modular microfluidics, use of capture regions, and injection into analytical devices on separate devices. In some embodiments star and nested star designs, or bead capture by change of cross sectional area of a channel in a microvalve are used. Movement of samples between temperature zones are further disclosed using fixed temperature and movement of the samples by micropumps. | 02-17-2011 |
William D. Nielsen, San Jose, CA US
Patent application number | Description | Published |
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20090253181 | Universal sample preparation system and use in an integrated analysis system - The invention provides for devices and methods for interfacing microchips to cartridges and pneumatic manifolds. The cartridges, microchips, and pneumatic manifolds can be integrated with downstream preparation devices, such as thermal regulating devices and separation and analysis devices. | 10-08-2009 |
20100165784 | INSTRUMENT WITH MICROFLUIDIC CHIP - This invention provides microfluidic devices that comprise a fluidics layer having microfluidic channels and one or more regulating layers that regulate the movement of fluid in the channels. The microfluidic devices can be used to mix one or more fluids. At least a portion of the fluidics layer can be isolated from the regulating layer, for example in the form of a shelf. Such isolated portions can be used as areas in which the temperature of liquids is controlled. Also provided are instruments including thermal control devices into which the microfluidic device is engaged so that the thermal control device controls temperature in the isolated portion, and a movable magnetic assembly including magnets with shields so that a focused magnetic field can be applied to or withdrawn from the isolated portion or any other portion of the microfluidic device. Also provided are methods of mixing fluids. The methods include stacking a plurality of alternating boluses of different liquids in a microfluidic channel, and moving the stacked boluses through the channel. In another method, the boluses are moved into a diaphragm valve having a volume able to accommodate several boluses, and then pumping the liquids out of the valve. | 07-01-2010 |
20110005932 | UNIVERSAL SAMPLE PREPARATION SYSTEM AND USE IN AN INTEGRATED ANALYSIS SYSTEM - The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft | 01-13-2011 |
20120115189 | MICROFLUIDIC AND NANOFLUIDIC DEVICES, SYSTEMS, AND APPLICATIONS - The present invention discloses the integration of programmable microfluidic circuits to achieve practical applications to process biochemical and chemical reactions and to integrate these reactions. In some embodiments workflows for biochemical reactions or chemical workflows are combined. Microvalves such as programmable microfluidic circuit with Y valves and flow through valves are disclosed. In some embodiments microvalves of the present invention are used for mixing fluids, which may be part of an integrated process. These processes include mixing samples and moving reactions to an edge or reservoir for modular microfluidics, use of capture regions, and injection into analytical devices on separate devices. In some embodiments star and nested star designs, or bead capture by change of cross sectional area of a channel in a microvalve are used. Movement of samples between temperature zones are further disclosed using fixed temperature and movement of the samples by micropumps. | 05-10-2012 |
20120315635 | Universal Sample Preparation System And Use In An Integrated Analysis System - The invention provides for devices and methods for interfacing microchips to cartridges and pneumatic manifolds. The cartridges, microchips, and pneumatic manifolds can be integrated with downstream preparation devices, such as thermal regulating devices and separation and analysis devices. | 12-13-2012 |
20130115607 | Sample Preparation, Processing and Analysis Systems - This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module. | 05-09-2013 |
20130224846 | Universal Sample Preparation System and Use in an Integrated Analysis System - The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft | 08-29-2013 |
20140045704 | MICROFLUIDIC AND NANOFLUIDIC DEVICES, SYSTEMS, AND APPLICATIONS - The present invention discloses the integration of programmable microfluidic circuits to achieve practical applications to process biochemical and chemical reactions and to integrate these reactions. In some embodiments workflows for biochemical reactions or chemical workflows are combined. Microvalves such as programmable microfluidic circuit with Y valves and flow through valves are disclosed. In some embodiments microvalves of the present invention are used for mixing fluids, which may be part of an integrated process. These processes include mixing samples and moving reactions to an edge or reservoir for modular microfluidics, use of capture regions, and injection into analytical devices on separate devices. In some embodiments star and nested star designs, or bead capture by change of cross sectional area of a channel in a microvalve are used. Movement of samples between temperature zones are further disclosed using fixed temperature and movement of the samples by micropumps. | 02-13-2014 |
20140170645 | UNIVERSAL SAMPLE PREPARATION SYSTEM AND USE IN AN INTEGRATED ANALYSIS SYSTEM - The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft | 06-19-2014 |
20140370519 | UNIVERSAL SAMPLE PREPARATION SYSTEM AND USE IN AN INTEGRATED ANALYSIS SYSTEM - The invention provides for devices and methods for interfacing microchips to cartridges and pneumatic manifolds. The cartridges, microchips, and pneumatic manifolds can be integrated with downstream preparation devices, such as thermal regulating devices and separation and analysis devices. | 12-18-2014 |
20150024436 | SAMPLE PREPARATION, PROCESSING AND ANALYSIS SYSTEMS - This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module. | 01-22-2015 |
20150136602 | UNIVERSAL SAMPLE PREPARATION SYSTEM AND USE IN AN INTEGRATED ANALYSIS SYSTEM - The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft | 05-21-2015 |
20150136604 | SAMPLE PREPARATION, PROCESSING AND ANALYSIS SYSTEMS - This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module. | 05-21-2015 |