| Patent application number | Description | Published |
| 20080255248 | Prodrug compounds with isoleucine - The compounds of the invention are modified forms of therapeutic agents. A typical prodrug compound of the invention comprises a therapeutic agent, an oligopeptide having an isoleucine residue, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by an enzyme associated with the target cell. Methods of making and using the compounds are also disclosed. | 10-16-2008 |
| 20090110753 | Enzyme-cleavable prodrug compounds - The prodrug of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the enzyme Thimet oligopeptidase, or TOP. Also disclosed are methods of designing prodrugs by utilizing TOP-cleavable sequences within the conjugate and methods of treating patients with prodrugs of the invention. | 04-30-2009 |
| 20090136980 | CD10-activated prodrug compounds - The compounds of the invention are modified forms of therapeutic agents. A typical prodrug compound of the invention comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the CD10 enzyme. Methods of treatment using the prodrug and methods of designing the prodrug are also disclosed. | 05-28-2009 |
| Patent application number | Description | Published |
| 20080220767 | Method, Telecommunication System and Telecommunication Handset for Wireless Communication and Telecommunication in a Smart Home Environment - In order to achieve simple, user-friendly “smart home” scenarios in a telecommunications system in the context of the transmission of textual, audio, video and/or control data between a data source and a data sink, a mobile element of the telecommunications system generates control commands and transmits the latter in a target manner in message traffic between the units that form part of the wireless communication or telecommunication process via the air interface. The mobile element is preferably configured as a cordless telephone handset or a mobile telephone. Textual, audio, video and/or control data that has been stored in the data source is detected, issued, released or externally transferred to a data sink or issued to a data source with the aid of the control commands. | 09-11-2008 |
| 20100159969 | MULTIMEDIA MESSAGE CENTER FOR DELIVERING A MULTIMEDIA MESSAGE TO A TELECOMMUNICATION DEVICE DURING AN ESTABLISHED TRAFFIC CHANNEL CONNECTION - The present application discloses an apparatus, system and method for reducing the time required for transmitting a multimedia message from any sender to any addressee and thus generally cut the cost of the multimedia message service. A traffic channel connection is kept to a receiving telecommunication device, which is established by a multimedia message service center that has received a multimedia message designated by a transmitting telecommunication device for said receiving telecommunication device, for example, in order to transmit an information message to the receiving telecommunication device during an SMS session by means of which the multimedia message service center informs the receiving telecommunication device about the arrival of the multimedia message, established for at least the period of time it takes the receiving telecommunication device to evaluate the received information message and hold an MMS session for fetching the message content of the multimedia message designated for the receiving telecommunication device from the multimedia message service center. | 06-24-2010 |