Patent application number | Description | Published |
20100203637 | Fluorescent cell markers - The preparation and use of fluorescent cell markers of the structure F—S | 08-12-2010 |
20100227402 | Cell Surface Coating with Hyaluronic Acid Oligomer Derivative - A method of localising reproduction assisting hyaluronic acid to reproductive cells surfaces by covalently linking it to lipids is disclosed. | 09-09-2010 |
20110171666 | PEPTIDE-LIPID CONSTRUCTS AND THEIR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS - Peptide-lipid constructs of the structure L-S—F are disclosed, where F is a peptide, S is a spacer covalently linking F to L via an oligomer of ethylene glycol, and L is a diacyl- or dialkyl-glycerolipid (including glycerophospholipids). The spacer ideally has 6 to 14 ethylene glycol repeats, corresponding to PEG with a molecular weight of approximately 250 to 600. Also disclosed is a method of detecting reactive antibodies in serum by contacting serum with cells modified to incorporate a peptide-lipid construct, where the peptide is an epitope of the antibody, and determining the degree of aggluthination of the cells. | 07-14-2011 |
20110213134 | Synthetic membrane anchors - The invention relates to synthetic molecules that spontaneously and stably incorporate into lipid by-layers, including cell membranes. Particularly, although not exclusively, the invention relates to the use of these molecules as synthetic membrane anchors or synthetic molecule constructs to effect qualitative and quantitative changes in the expression of cell surface antigens. | 09-01-2011 |
20120277416 | CELL SURFACE COATING WITH HYALURONIC ACID OLIGOMER DERIVATIVE - A method of localising reproduction assisting hyaluronic acid to reproductive cell surfaces by covalently linking it to lipids is disclosed. | 11-01-2012 |
20130018195 | FLUORESCENT CELL MARKERS - The preparation and use of fluorescent cell markers of the structure F—S | 01-17-2013 |
20130280746 | PEPTIDE-LIPID CONSTRUCTS AND THEIR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS - Peptide-lipid constructs of the structure L-S-F are disclosed, where F is a peptide, S is a spacer covalently linking F to L via an oligomer of ethylene glycol, and L is a diacyl- or dialkyl-glyccrolipid (including glyccrophospholipids). The spacer ideally has 6 to 14 ethylene glycol repeats, corresponding to PEG with a molecular weight of approximately 250 to 600. Also disclosed is a method of detecting reactive antibodies in serum by contacting serum with cells modified to incorporate a peptide-lipid construct, where the peptide is an epitope of the antibody, and determining the degree of agglutination of the cells. | 10-24-2013 |
20140186950 | SYNTHETIC MEMBRANE ANCHORS - Cells incorporating a synthetic molecule construct of the structure F—S | 07-03-2014 |
20140371437 | CELL SURFACE COATING WITH HYALURONIC ACID OLIGOMER DERIVATIVE - A method of localizing reproduction assisting hyaluronic acid to reproductive cell surfaces by covalently linking it to lipids is disclosed. | 12-18-2014 |