Nicholas
Benjamin-Leo Nicholas, Dorset GB
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20120183950 | TISSUE ANALYSIS - The present invention provides a method of tissue analysis, disease modelling or drug development comprising the steps of providing a tissue sample comprising cells of at least two different cell types; exposing cells in the tissue sample to an agent ex vivo; exposing the cells to three or more detection means arranged to distinguish between three or more different cell types and/or different cell states; detecting the detection means in order to determine the different cell types and/or different cell states in the sample. The invention further provides a kit for performing the method of the invention and uses of the method of the invention. | 07-19-2012 |
Christian V. Nicholas, Herfordshire GB
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20100068387 | INK FOR PRINTING ON LOW ENERGY SUBSTRATES - The invention provides an aqueous inkjet ink composition comprises a polymeric compound comprising discrete particles responsive to an external stimulus, and a functional material, wherein the functional material may be incorporated as part of the polymeric particles, the particles causing the composition to have a first rheological state and a different second rheological state in response to a stimulated change in conditions, the first rheological state being associated with a first lower viscosity of the composition, wherein the particles have a first lower volume, enabling the composition to pass through an inkjet printhead orifice and the second rheological state being associated with a second higher viscosity of the composition, wherein the particles have a second higher volume, enabling immobilisation of droplets of the composition on a substrate. The inkjet composition is particularly useful in a continuous inkjet printing system for printing onto a wide range of surfaces including impermeable surfaces. | 03-18-2010 |
Deon Chris Nicholas, Kitchener CA
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20150134602 | ATOMIC UPDATE OPERATIONS IN A DATA STORAGE SYSTEM - Technology is disclosed for performing atomic update operations in a storage system (“the technology”). The technology can receive an update command to update a value associated with a key stored in the storage system as a function of an input value; store the input value in a log stored at the storage system but not updating the value stored in the storage system; and update the value associated with the key with the received input values value based on the a function to generate an updated value, the updating occurring asynchronously with respect to receiving the update command. | 05-14-2015 |
Dolly Nicholas, Marabella TT
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20140026785 | SYNTHETIC MODIFIER FOR HOT ASPHALTIC MIXES FOR ROAD PAVING AND METHOD OF MAKING SAME - A synthetic modifier known as JSSM for hot asphaltic paving mixes is formed of refinery bitumen, of which one example is 60/70 penetration grade, and clay and/or sand that is siloxane bonded. Another component may be a UV absorber. The synthetic modifier is added to refinery bitumen to produce a paving asphalt cement. | 01-30-2014 |
20150203654 | INORGANIC MODIFIER FOR HOT MIX ASPHALT FOR ROAD BUILDING AND METHOD OF MAKING SAME - An organic modifier for hot mix asphalt containing one or more components of clay, feldspar, kaolinite or sand which absorb or adsorb oil. All or some of the components may be silane coupled. The modifier may include a clay which prevents the sedimentation of the asphalt to which it is added. The modifier is added to molten asphalt and stirred with the asphalt until homogeneous therewith. | 07-23-2015 |
Gareth Nicholas, Reading GB
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20110249219 | INTEGRATED DISPLAY AND PHOTOVOLTAIC ELEMENT - A display device includes a first layer having an optically active display portion, a second layer including a photovoltaic element, and a third layer including electronics operatively coupled to the first layer, wherein the electronics are configured to drive the optically active display portion. Further, the second layer is arranged between the first and third layers. | 10-13-2011 |
Gareth Nicholas, Oxford GB
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20110012125 | THIN FILM TRANSISTOR AND ACTIVE MATRIX DISPLAY - A thin film transistor is formed in a semiconductor island on an insulating substrate. The transistor comprises a source ( | 01-20-2011 |
Gareth Nicholas, Great Milton GB
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20120061802 | BIPOLAR JUNCTION TRANSISTOR - A bipolar junction transistor includes a semiconductor island on an insulating substrate; an emitter and at least one of a collector and sub collector within the semiconductor island, the emitter and the at least one of the collector and the sub collector being of a first conductivity type; a base within the semiconductor island separating the emitter and the at least one of the collector and the sub collector, the base being of a second conductivity type; a base contact region within the semiconductor island, the base contact region being of the second conductivity type; and a connecting base region adjacent the base within the semiconductor island and connecting the base to the base contact region while not directly contacting the emitter, the connecting base region being of the second conductivity type with a doping concentration less than a doping concentration of the base contact region. | 03-15-2012 |
Gina Diane Nicholas, Hamilton NZ
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20090324590 | MYOSTATIN ANTAGONISTS - An isolated recombinant polypeptide having myostatin antagonist activity, comprising a C-terminally truncated mature myostatin peptide, wherein the C-terminal truncation is at a position at or between amino acids 281 and 329, or a fragment, variant or derivative thereof. | 12-31-2009 |
20130065820 | SYNTHETIC MYOSTATIN PEPTIDE ANTAGONISTS - The present invention relates to novel synthetic myostatin antagonists, comprising a synthetic mature myostatin peptide, wherein the peptide comprises at least two cysteine residues at positions | 03-14-2013 |
Greatex Nicholas, Aachen DE
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20140114202 | BLOOD WITHDRAWAL CANNULA OF A PUMP REPLACING OR ASSISTING ACTIVITY OF THE HEART - The invention relates to a blood withdrawal cannula ( | 04-24-2014 |
Jason Nicholas, Mississauga CA
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20140271108 | COMPRESSOR BLEED SELF-RECIRCULATING SYSTEM - A compressor for a gas turbine engine having a bleed air recirculation system includes a plurality of bleed holes extending through the shroud at a first axial location thereon substantially adjacent the blade tips. The bleed holes have a closed outer perimeter along their complete length. An annular bleed cavity surrounds the shroud and is in communication with outlet openings of the bleed holes. The bleed holes provide communication between said main gas flow passage and the bleed cavity. The bleed cavity includes exit passages having outlets disposed in said shroud at a second axial location which is upstream of both the first axial location and the leading edge of the blades of the rotor. Bleed air is passively bled from the main gas flow passage via the bleed holes, recirculated through the bleed cavity and re-injected back into the main gas flow passage at the second axial location. | 09-18-2014 |
Kevin Roy Nicholas, Victoria AU
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20100035803 | Polypeptides and Polynucleotides Encoding the same - Provided herein are lactation-associated polypeptides and polynucleotides, expression vectors a host cells for expressing lactation-associated polypeptides and polynucleotides, and methods of producing said polypeptides and polynucleotides. | 02-11-2010 |
20110201105 | LACTATION-ASSOCIATED POLYPEPTIDES - The invention relates to cDNA libraries obtained from Tammar wallaby ( | 08-18-2011 |
Malcolm G. Nicholas, Berks GB
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20100099426 | TELECOMMUNICATION NETWORK - A telecommunication network including: a radio access network; and a network switching subsystem operable for communication with the radio access network and with a demand-driven, dynamically-configurable IP based computing infrastructure. | 04-22-2010 |
20130005311 | TELECOMMUNICATION NETWORK - A method of communicating a telecommunication request initiated by a subscriber in a telecommunication network. The method according to an embodiment includes: receiving a request for a voice or data communication by a radio access network; and communicating the received request to a network switching subsystem for processing by a demand-driven, dynamically-configurable IP based computing infrastructure. | 01-03-2013 |
Marty Nicholas, Sydney AU
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20110295648 | Computer and Computer Program for Evaluating the Sales Force Effectiveness of a Selected Business - A computer for evaluating the sales force effectiveness of a selected business includes a processor, a data communication device operatively connected to the processor and computer readable memory operatively connected to the processor and storing a program. The program comprises code adapted to calculate a final score representing the sales force effectiveness of the selected business by calculating the difference between the sales force effectiveness score of the selected business and a sales force effectiveness benchmark score which it also calculates. Also provided are computer executable steps for evaluating the sales force effectiveness of a selected business. Finally provided is a computer program product comprising a computer usable medium having a computer readable program code embodied therein, the computer readable program code adapted to be executed to implement a method for evaluating the sales force effectiveness of a selected business. | 12-01-2011 |
Nico Nicholas, London GB
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20100307933 | GREETING CARD AND GIFT PACKAGE COMBINATION - The Combination Greeting Card & Gift Package is a gift card that can have a personal message written inside, but also with a compartment containing a gift, such as chocolates, jelly beans or any other type of gift. The invention has extension flaps (G, K) which seal the inner compartment in order to hold the gift inside, and at the same time, make the package ready for posting. When received the removable or tear-off segments so the outer packaging can be removed, leaving a greetings card that can be stood up as a regular greeting card. | 12-09-2010 |
O'Hear Nicholas, Schonhoven NL
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20100071340 | CABLE,COMBINED CABLE MAADE OF PLASTIC FIBERS AND STEEL WIRE STRANS, ANDCOMBINED ATRANDS MADE OF PLASTIC FIBERS AND STEEL WIRES - A combined cable comprising a core cable of high-strength synthetic fibers, which take the form of a twisted bundle of monofilaments or a plurality of twisted bundles of monofilaments, and comprising an outer layer of steel wire strands, is characterized in that the bundle or bundles of monofilaments is or are stretched, with a reduction in diameter, and held in this state by a sheathing, in particular a braided sheathing. The extension under strain of the core cable under load is thereby reduced, so that the load distribution between the cross section of steel and the cross section of synthetic material of the cable improves. | 03-25-2010 |
Olaf Nicholas, Kitzingen DE
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20110180480 | REVERSE-OSMOSIS SYSTEM WITH AN APPARATUS FOR REDUCING NOISE AND METHOD FOR REDUCING NOISE IN A REVERSE-OSMOSIS SYSTEM - The present invention relates to a reverse osmosis system having an apparatus for noise cancellation of the reverse osmosis system, wherein the apparatus has at least one sensor for the detection of at least one noise emitted by the reverse osmosis system; at least one controller connected to the sensor for the evaluation of the signal or signals obtained from the sensor; and at least one actuator connected to the controller, with the actuator being designed such that it generates an acoustic signal or a vibration by means of which the noise emitted by the reverse osmosis system is damped or cancelled out. | 07-28-2011 |
20130333795 | CONCENTRATE CONTAINER HAVING SUPPORTING ELEMENTS - The invention relates to a container for dialysis concentrates, in particular acidic dry concentrates. When these dry concentrates are dissolved directly by the dialysis machine to form liquid concentrates, the containers must provide a volume of 4-12 liters. To impart the required stability to these containers, they have integral supporting elements, which manifest their supporting function only when the container is used on the dialysis machine. | 12-19-2013 |
Olaf Nicholas, Kiltzingen DE
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20090205426 | Method and device for monitoring a flowing liquid for the presence of air - The present invention relates to a method and a device for monitoring a flowing medium, in particular the blood flowing in an extracorporeal blood circulation, for the presence of air, in particular micro-bubbles. A sequence of signal pulses or a continuous signal is injected into the flowing medium, and the signal pulses or continuous signal leaving the flowing medium are received. To detect micro-bubbles, a signal pattern that is characteristic of the variation over time of the received signal pulses or the continuous signal in a predetermined period of time is extracted from the signal received. The characteristic signal pattern is compared with one or more characteristic reference patterns, and the presence of air bubbles is determined if the characteristic signal pattern deviates from the characteristic reference pattern by a predetermined amount. Statistical characteristic variables, in particular the variance, are preferably determined from the signal patterns and compared with one another. | 08-20-2009 |
Paul Nicholas, Ottawa CA
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20090154484 | SCALEABLE VOIP TELEPHONE LINE CIRCUIT - A telephone subscriber line device for providing an interface between a legacy telephone circuit based on circuit-switched technology and a packet network has a legacy interface for connection to telephone circuit; a packet interface for connection to a packet network, processing circuitry for converting between legacy telephone signals and packet signals, and a cascadable expansion bus permitting multiple said devices to be connected to a common port on a packet network. Such a device is highly scalable. | 06-18-2009 |
Richard Nicholas, London Greater London GB
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20160059966 | SEATING ARRAY FOR AN AIRCRAFT CABIN - A seating array for an aircraft cabin comprises a plurality of passenger modules. Each module is defined by first and second end walls, includes a seat assembly and an ottoman, and has at least one door assembly moveable from a stowed position to a deployed position. The end walls extend substantially transversely to a longitudinal centerline of the aircraft cabin and are connected by at least one sidewall which defines an entrance to the module. When in the deployed position, the doorway will at least partially obstruct the entrance. The ottoman is spaced in a longitudinal direction of the array from the seat assembly. Each module is wider adjacent the seat assembly than adjacent the ottoman. The plurality of passenger modules is divided into at least two columns of modules, each column including at least two modules, the at least two columns being separated by an aisle. | 03-03-2016 |
Timothy Nicholas, Alton GB
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20120117930 | PLASMA TREATED FILTER - A method, including receiving a turbine filter unit in a plasma treatment system, wherein the turbine filter unit comprises a filter media assembled with a framework, and applying at least one plasma treatment coating to the turbine filter unit via the plasma treatment system. | 05-17-2012 |
Timothy John Nicholas, Calmore GB
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20140144320 | CARTRIDGE FILTER DIMENSIONAL COMPENSATOR - A cartridge filter insert includes a body, an internal opening, and an exterior surface. The internal opening is configured to permit an airflow through the body. The exterior surface is configured to removably engage a surface of a cartridge filter having an outlet. The internal opening has an inside dimension smaller than an inside dimension of the outlet of the cartridge filter to effectively reduce the inside dimension of the outlet. An inlet filter house including the cartridge filter and the cartridge filter insert are also provided. Methods of filtering a fluid using the cartridge filter and the cartridge filter insert within the inlet filter house are also provided. | 05-29-2014 |
20150113938 | WEATHER HOOD WATER REMOVAL SYSTEM AND METHOD FOR ASSEMBLY - An air intake system for use with a gas turbine is provided. The air intake system includes a weather hood coupled to a filter house. The air intake system also includes a prefilter assembly configured within said weather hood, wherein said prefilter assembly includes at least three air filtration units, including at least one moisture separator and at least one coalescing filter. | 04-30-2015 |
Timothy John Nicholas, Calmore Hampshire GB
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20110289894 | FILTER ELEMENT OF MICROGLASS & NONWOVEN SUPPORT LAYER MEDIA - A composite filter element is provided. The composite filter element is configured for filtering fluid. The composite filter element includes a microglass media of glass fibers and a scrim laminated to the microglass media. The scrim is configured to provide support for the microglass media. In one aspect, the composite filter element has a filtration efficiency greater than or equal to about 99.5% for capturing a particle size of about 0.3 microns. In another aspect, a frame is provided that is configured to hold the at least one composite filter element in a V-shaped pocket and a basis weight of the microglass media and the scrim is at least about 90 g/m | 12-01-2011 |
Timothy John Nicholas, Hampshire GB
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20110277430 | FILTER MEDIA PLEAT PACK RETENTION - An approach that provides filter media pleat pack retention is described. In one embodiment, filter media pleat pack retention is attained by providing a filter media pleat pack having a joining member located between a first filter media portion and a second filter media portion. The first filter media portion is coupled to the joining member at one side and the second filter media portion is coupled to the joining member at an opposite side. The joining member provides stiffness to the filter media pleat pack and provides support to the panel stopping excessive bowing under high pressure and subsequent tearing and puncture. | 11-17-2011 |
Timothy John Nicholas, Southampton GB
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20110252759 | FILTER - A filter assembly includes a frame for mounting the filter assembly. The frame defines a rectangular opening. A channel is disposed about at least a portion of the periphery of the rectangular opening. Filter media pleat pack is disposed in the channel in the frame. The filter media pleat pack extends across the entire rectangular opening in the frame. The filter media pleat pack separates particles from a gas flowing through the filter media in a first direction. Support structure is connectable with the frame. The support structure engages the filter media pleat pack to limit movement of the filter media pleat pack when gas flows in the first direction through the filter media. | 10-20-2011 |
20120255268 | MOISTURE REDUCING APPARATUS - A moisture reducing apparatus is provided that includes a housing configured to receive an air stream and a net disposed outside the housing. In the apparatus, the net is held sufficiently loosely to permit movement of the net such that flow through the net is variable over time to remove moisture with the net and to permit a relatively substantial portion of a gaseous and particulate matter in the air stream to continue to flow through the net and inside the housing to protect filter media from moisture. | 10-11-2012 |
20140202235 | CARTRIDGE FILTER ROBUSTNESS TESTING - A method includes providing at least one filter element in a test rig. The at least one filter element separates a clean side from a dirty side within the test rig. The pressure differential between the clean side and the dirty side is measured. The pressure differential between the clean side and the dirty side is increased by filtering particulate matter and fluid from an air flow within the test rig. The at least one filter element is cleaned. The previous three steps are repeated to replicate the conditions the at least one filter element is subjected to during substantially the entire life cycle of the at least one filter element. | 07-24-2014 |
20140360217 | COOLING SYSTEM FOR USE IN A TURBINE ASSEMBLY AND METHOD OF ASSEMBLY - A cooling system for use in a turbine assembly is provided. The cooling system includes a first filter configured to remove particles entrained in a flow of intake air, an array of nozzles downstream from the first filter, and a second filter downstream from the array. The array of nozzles is configured to facilitate reducing a temperature of the intake air, and the second filter is configured to repel cooling liquid discharged from the array of nozzles while allowing cooled intake air to flow therethrough. | 12-11-2014 |
Tyrone Nicholas, Croydon GB
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20140081805 | SOFTWARE PRODUCT REVIEW SYSTEM AND METHOD - A customer with a customer device performs a search for reviews of a particular software product of interest to the customer. The customer is then presented with entries from reviewers that have the same device as the customer, or a device on which the product is expect to run or operate in a manner similar to how it runs on the customer's device. | 03-20-2014 |