Patent application number | Description | Published |
20090232734 | ANTI-TISSUE FACTOR ANTIBODIES AND COMPOSITIONS - Isolated anti-tissue factor antibodies, immunoglobulins, cleavage products and other specified portions and variants thereof having enhanced ADCC activity, as well as anti-tissue factor antibody compositions, encoding or complementary nucleic acids, vectors, host cells, compositions, formulations, devices, transgenic animals, transgenic plants, and methods of making and using thereof. The antibodies of the invention bind human tissue factor and demonstrate enhanced ADCC activity. Accordingly, the antibodies can be used in a variety of methods for diagnosing, treating, and/or preventing diseases involving tissue factor, where enhanced ADCC activity is desirable such as cancer. | 09-17-2009 |
20140079628 | ANTI-TISSUE FACTOR ANTIBODIES AND COMPOSITIONS - Isolated anti-tissue factor antibodies, immunoglobulins, cleavage products and other specified portions and variants thereof having enhanced ADCC activity, as well as anti-tissue factor antibody compositions, encoding or complementary nucleic acids, vectors, host cells, compositions, formulations, devices, transgenic animals, transgenic plants, and methods of making and using thereof. The antibodies of the invention bind human tissue factor and demonstrate enhanced ADCC activity. Accordingly, the antibodies can be used in a variety of methods for diagnosing, treating, and/or preventing diseases involving tissue factor, where enhanced ADCC activity is desirable such as cancer. | 03-20-2014 |
Patent application number | Description | Published |
20110263884 | Process for Preparing Saturated Branched Chain Fatty Acids - A process for preparing saturated branched chain fatty acids or alkyl esters thereof involving subjecting unsaturated fatty acids having 10 to 25 carbon atoms, alkyl esters thereof or mixtures thereof to a skeletal isomerization reaction in the presence of water or a lower alcohol at a temperature of about 240° C. to about 280° C. using a combination of a stericly hindered Lewis base and zeolite as a Brönsted or Lewis acid catalyst, and isolating saturated branched chain fatty acids or alkyl esters thereof or mixtures thereof from the reaction mixture obtained by the skeletal isomerization reaction. The yield of said saturated branched chain fatty acids is ≧70 wt %. The stericly hindered Lewis base is a tertiary amine or phosphine with linear or branched C1 to C6 alkyl or phenyl groups attached thereto. | 10-27-2011 |
20110275844 | Process for Preparing Saturated Branched Chain Fatty Acids - A process for preparing saturated branched chain fatty acids or alkyl esters thereof involving subjecting unsaturated fatty acids having 10 to 25 carbon atoms, alkyl esters thereof or mixtures thereof to a skeletal isomerization reaction in the presence of water or a lower alcohol at a temperature of about 240° C. to about 280° C. using a combination of a stericly hindered Lewis base and zeolite as a Brönsted or Lewis acid catalyst, and isolating saturated branched chain fatty acids or alkyl esters thereof or mixtures thereof from the reaction mixture obtained by the skeletal-isomerization reaction. The yield of said saturated branched chain fatty acids is ≧70 wt %. The stericly hindered Lewis base is a tertiary amine or phosphine with linear or branched C1 to C6 alkyl or phenyl groups attached thereto. | 11-10-2011 |
20130310587 | Process for Preparing Saturated Branched Chain Fatty Acids - A process for preparing saturated branched chain fatty acids or alkyl esters thereof involving subjecting unsaturated fatty acids having 10 to 25 carbon atoms, alkyl esters thereof or mixtures thereof to a skeletal isomerization reaction in the presence of water or a lower alcohol at a temperature of about 240° C. to about 280° C. using a combination of a sterically hindered Lewis base and zeolite as a Brönsted or Lewis acid catalyst, and isolating saturated branched chain fatty acids or alkyl esters thereof or mixtures thereof from the reaction mixture obtained by the skeletal isomerization reaction; wherein the process further comprises (a) recycling said catalyst by washing said catalyst with an acid solution at about 55° C. for about 24 hours, recovering the catalyst followed by heating the catalyst at about 115° C. for about 20 hours for the first four or five cycles of use and (b) in the next subsequent cycle recycling the catalyst by heating the catalyst at about 115° C. for about 20 hours followed by adding Lewis base to the catalyst; steps (a) and (b) can be repeated in subsequent cycles. The yield of said saturated branched chain fatty acids is ≧70 wt %. The sterically hindered Lewis base is a tertiary amine or phosphine with linear or branched C1 to C6 alkyl or phenyl groups attached thereto. | 11-21-2013 |
Patent application number | Description | Published |
20080293267 | ELECTRICAL CONNECTOR WITH STRESS-DISTRIBUTION FEATURES - A connector capable of being mounted onto a substrate is disclosed. Such a connector may include a housing, and a contact mounted within the housing. The contact may include a body, terminal pins extending from a first edge of the body, contact beams extending from a second edge of the body, and a flared portion. The edges of a first contact beam and a second contact beam of the contact beams may be positioned proximate respective adjacent surfaces of the housing. The flared portion may also be positioned proximate a respective adjacent surface of the housing. The relationship between the first contact beam and its respective adjacent surface, the relationship between the second contact beam and its respective adjacent surface, and the relationship between the flared portion and its respective surface may inhibit bowing of the body of the contact when the connector is mounted on the substrate. | 11-27-2008 |
20090042417 | ELECTRICAL CONNECTORS HAVING POWER CONTACTS WITH ALIGNMENT/OR RESTRAINING FEATURES - Preferred embodiments of power contacts have alignment features that can maintain conductors of the power contacts in a state of alignment during and after insertion of the power contacts into a housing. | 02-12-2009 |
20090088028 | POWER CONNECTORS WITH CONTACT-RETENTION FEATURES - A power receptacle contact may include first and second contact beams that deflect independently of one another during mating of the power receptacle contact with a complementary blade contact. Each beam may extend from abutting respective body portions. The power receptacle contact may include a first clip that extends from the first contact beam. The first clip may define a blade receiving area between the first and second contact beams. A power connector may include a housing and a contact received in the housing. The contact may includes first and second protrusions that prevent the contact from moving in a first direction. | 04-02-2009 |
20100029126 | ELECTRICAL COMMUNICATION SYSTEM HAVING LATCHING AND STRAIN RELIEF FEATURES - An electrical communication system includes at least one electrical connector system that includes a header connector configured to mate with a receptacle connector through a back panel. The connector system includes a latch that releasably mates the header and receptacle connectors. The receptacle connector is mounted to a substrate, such as a printed circuit board, and the header connector is connected to a power cable assembly. The power cable assembly includes a faston that electrically connects a power cable to the electrical contacts of the header connector. | 02-04-2010 |
20100075528 | CABLE CONNECTOR - A cable connector includes an electrical contact configured to receive a cable at one end, and an electrical component at another end. The contact can be constructed as a one-piece contact body or a two-piece contact body, and the contact body can include a cable lock that assists in retaining the cable in the contact body. | 03-25-2010 |
20100184339 | LOW PROFILE POWER CONNECTOR HAVING HIGH CURRENT DENSITY - A receptacle power connector is provided having first and second rows of electrical power contacts retained in a connector housing. The connector housing has a low profile, and the power contacts are arranged in rows that each achieves a current density of about 120 Amps/linear inch (2.54 cm). | 07-22-2010 |
20100197166 | ELECTRICAL CONNECTOR HAVING POWER CONTACTS - An electrical power connector is provided that is configured to mate with a complementary electrical connector. The electrical power connector includes a connector housing that retains both electrical signal contacts and electrical power contacts. The electrical power connector includes an engagement assembly that includes 1) at least one polarization member configured to mate with a polarization member of the complementary electrical connector only when the electrical power connector is in a desired orientation relative to the complementary electrical connector, and 2) a securement member configured to releasably engage a securement member of the complementary electrical connector. | 08-05-2010 |
20100330846 | ELECTRICAL POWER CONNECTOR SYSTEM - An electrical power connector comprises a housing having a mounting interface and a mating interface. The mating interface defines a plurality of receptacles spaced apart in more than one direction. A plurality of electrical contacts is supported by the housing. These electrical contacts define respective mounting ends that are configured to electrically connect with an electrical component at the mounting interface, and opposed mating ends. At least one of the electrical contacts defines a common contact beam disposed within at least a select one of the receptacles. This common contact beam is configured to be electrically connected to a pair of adjacent electrical contacts of a mated electrical connector. | 12-30-2010 |
20110151701 | CARD-EDGE CONNECTOR - A card-edge connector may provide a physically secure attachment to a substrate without the use of removable hardware. The card-edge connector may include a straddle-mount card-edge connector housing and a retention assembly that extends from the connector housing. The retention assembly configured to releasably secure the connector to the substrate. | 06-23-2011 |
20110300759 | ELECTRICAL CARD-EDGE CONNECTOR - A card-edge connector has a housing that includes a housing body, and a plurality of electrical contacts carried by the housing body. The electrical contacts include a plurality of electrical signal contacts and a plurality of electrical power contacts. The electrical signal contacts are sized thinner than the electrical power contacts. The card-edge connector includes a mounting fastener extending out from only one side wall of the housing body at a location adjacent the electrical signal contacts. | 12-08-2011 |
20110300760 | ELECTRICAL CARD-EDGE CONNECTOR - A card-edge connector has a housing that includes a housing body, and a plurality of electrical contacts carried by the housing body. The housing is devoid of mounting ears that would extend out from the housing body. Rather, the housing includes opposing mounting guides carried by opposed housing side walls that are configured to receive a complimentary circuit board that the card-edge connector is mounted to. | 12-08-2011 |