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Negulescu
Cristina G. Negulescu, Santa Clara, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090202608 | Devices, formulations, and methods for delivery of multiple beneficial agents - The present invention relates to osmotic delivery devices, formulations, and methods for delivery of two or more beneficial agents. In one aspect, the present invention provides osmotic delivery devices useful for substantially concurrent administration of two or more beneficial agents. In another aspect, the present invention provides beneficial agent formulations for use in the osmotic delivery devices. The formulations include formulations wherein beneficial agents are soluble in the vehicle, suspension formulations comprising particle formulations of one or more beneficial agent, and combinations thereof. Further, methods for treatment of a variety of diseases or conditions using two or more beneficial agents are disclosed, wherein the methods are preferably practiced using the osmotic delivery devices and/or formulations of the invention. | 08-13-2009 |
Dimitrie Negulescu, Berlin DE
| Patent application number | Description | Published |
|---|---|---|
| 20090025363 | Vent for the lubricating oil system of a jet engine - The air exit hole of the vent line ( | 01-29-2009 |
| 20100155526 | AIRCRAFT WITH TAIL PROPELLER-ENGINE LAYOUT - An aircraft propeller-engine layout includes at least one engine ( | 06-24-2010 |
| 20100212285 | TURBOPROP PROPULSION UNIT WITH PUSHER PROPELLER - A turboprop propulsion unit includes at least one pusher propeller | 08-26-2010 |
| 20100215481 | RUNNING-GAP CONTROL SYSTEM OF AN AIRCRAFT GAS TURBINE - A running-gap control system of an aircraft gas turbine with a core engine including a turbine whose blade rows have a running gap | 08-26-2010 |
| 20110209458 | Aircraft gas turbine engine - The invention refers to an aircraft gas turbine engine including a core engine | 09-01-2011 |
Paul Negulescu, Solana Beach, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090162926 | PHOTON REDUCING AGENTS FOR FLUORESCENCE ASSAYS - The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides a method for reducing undesirable light emission from a sample (e.g. a biochemical or cellular sample) with at least one photon producing agent and at least one collisional quencher. The present invention also provides a method for reducing undesirable light emission from a sample (e.g., a biochemical or cellular sample) with at least one photon producing agent and at least one quencher, such as an electronic quencher. The present invention also provides a system and method of screening test chemicals in fluorescent assays using photon reducing agents. The present invention also provides compositions, pharmaceutical compositions, and kits for practicing these methods. | 06-25-2009 |
| 20110076711 | PHOTON REDUCING AGENTS FOR FLUORESCENCE ASSAYS - The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides a method for reducing undesirable light emission from a sample (e.g., a biochemical or cellular sample) with at least one photon producing agent and at least one collisional quencher. The present invention also provides a method for reducing undesirable light emission from a sample (e.g., a biochemical or cellular sample) with at least one photon producing agent and at least one quencher, such as an electronic quencher. The present invention also provides a system and method of screening test chemicals in fluorescent assays using photon reducing agents. The present invention also provides compositions, pharmaceutical compositions, and kits for practicing these methods. | 03-31-2011 |
Paul Adrian Negulescu, Del Mar, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110288122 | Pharmaceutical Compositions and Administrations Thereof - The present invention relates to the use of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, solids forms, and pharmaceutical compositions thereof for the treatment of CFTR mediated diseases, particularly cystic fibrosis, in patients possessing specific genetic mutations. | 11-24-2011 |
Radu Negulescu, Galati RO
| Patent application number | Description | Published |
|---|---|---|
| 20090201248 | Device and method for providing electronic input - An input apparatus comprises an input device comprising a shuttle capable to move substantially within a two-dimensional surface when engaged by a user member. The input device and a display are communicatively connected to a host. A cursor is displayed and moved on the display. The shuttle is moved by engaging it and there is kinesthetic or tactile feedback to a user depending on the position of said shuttle within the surface. The feedback indicates that the shuttle travels to one of several preset positions. The input device is biased towards the nearest position within a set of predetermined locations. The cursor is moved in a direction and by a distance substantially similar to the direction and distance traveled by said shuttle. The shuttle may be depressed to select items on the display. | 08-13-2009 |