| Patent application number | Description | Published |
|---|
| 20080300241 | Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods - Non-steroidal tricyclic quinolinone and tricyclic quinoline compounds and compositions that are agonists, partial agonists and/or antagonists for androgen receptors (AR), their preparation and their uses are described. | 12-04-2008 |
| 20090076268 | Facile assembly of fused benzofuro-heterocycles - This invention concerns the synthesis of polycyclic structural components of pharmacological compounds, including the synthesis of fused benzofuro-heterocycles, through selective palladium-catalyzed cross-coupling and intramolecular cyclization. | 03-19-2009 |
| 20090093637 | Synthesis of 1,3,4-Trisubstituted and 1,3,4,5-Tetrasubstituted Pyrazoles - This invention concerns the synthesis of highly substituted pyrazoles, which are structural components of pharmacological compounds, through reaction of hydrazones with nitroolefins. | 04-09-2009 |
| 20090099157 | TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S - Tetrahydro-pyrazolo-pyridine thioether compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis. | 04-16-2009 |
| 20090124801 | Process for synthesizing phosphonic and phosphinic acid compounds - The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds. | 05-14-2009 |
| 20090258854 | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase - Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity. | 10-15-2009 |
| 20090264429 | Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase - Certain aryl-hydroxyethylamino-pyrimidine and triazine compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis). Methods of synthesizing such compounds are also disclosed. | 10-22-2009 |
| 20090291903 | SUBSTITUTED PYRROLIDINE AMIDES AS MODULATORS OF THE HISTAMINE H3 RECEPTOR - Certain substituted pyrrolidine amide compounds are histamine H | 11-26-2009 |
| 20100004450 | Process for the preparation of substituted pyrimidine derivatives - The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H | 01-07-2010 |
| 20100029942 | Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives - The present invention is directed to benzoimidazol-2-yl pyrimidine derivatives useful as histamine H | 02-04-2010 |
| 20100197689 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES - The present invention is directed to novel processes for the preparation of substituted piperazinyl and diazepanyl benzamides, useful for the treatment of disorders and conditions mediated by the histamine receptor. | 08-05-2010 |
| 20100267701 | SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR - Certain substituted pyridyl amide compounds are histamine H | 10-21-2010 |
| 20100286391 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES - The present invention is directed to novel processes for the preparation of cyclopropyl-amide derivatives, useful for the treatment of disorders and conditions mediated by the histamine receptor. | 11-11-2010 |
| 20110159563 | Thyazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase - Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity. | 06-30-2011 |
| 20110160451 | 2-Aminopyrimidine modulators of the histamine H4 receptor - 2-Aminopyrimidine compounds are described, which are useful as H | 06-30-2011 |
| 20110160452 | 2-Aminopyrimidine modulators of the histamine H4 receptor - 2-Aminopyrimidine compounds are described, which are useful as H | 06-30-2011 |
