| Patent application number | Description | Published |
|---|
| 20080306054 | Pharmaceutical Compounds - The invention provides a compound for use as an inhibitor of Hsp90, the compound having the formula (I): | 12-11-2008 |
| 20080306069 | Pyrazole Derivatives for the Inhibition of CDK'S and GSK'S - The invention provides compounds of the formula (I), or salts, tautomers, N-oxides or solvates thereof wherein: R1 is selected from: (a) 2,6-dichlorophenyl; (b) 2,6-difluorophenyl; (c) a 2,3,6-trisubstituted phenyl group wherein the substituents for the phenyl group are selected from fluorine, chlorine, methyl and methoxy; (d) a group RO; (e) a group R a; (f) a group RIb; (g) a group RIc; (h) a group RId; and 0) 2,6-difluorophenylamino; wherein R) 0υ, r R>llaa, T Rj HbD, T R) HcC, r R>Iidα, r R>>2zaa, r R>22bD and RJ are as defined in the claims. The compounds have activity as inhibitors of cdk kinase (such as cdk1 or cdk2) and glycogen synthase kinase-3 activity. | 12-11-2008 |
| 20090215772 | Hydroxybenzamide derivatives and their use as inhibitors of HSP90 - The invention provides compounds of the formula (I): | 08-27-2009 |
| 20090318500 | 4-(2, 6-Dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide for the Treatment of Cancer - The invention provides the compound of formula (I) 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide in a substantially crystalline form, therapeutic uses thereof and pharmaceutical compositions containing the crystalline compound. The invention also provides novel pharmaceutical formulations containing 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide and novel processes for preparing the compound. | 12-24-2009 |
| 20100160324 | PYRAZOLE DERIVATIVES AS THAT MODULATE THE ACTIVITY OF CDK, GSK AND AURORA KINASES - The invention provides a compound of the formula (I): for use in medicine: or salts or tautomers or N-oxides or solvates thereof; wherein R | 06-24-2010 |
| 20100216782 | HYDROXYBENZAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF HSP90 - This invention provides methods for treating, alleviating or reducing the incidence of a disease or condition comprising or arising from abnormal cell growth in a mammal, which comprise administering to the mammal a compound, salt, hydrate, tautomer or N-oxide according to formula (I): | 08-26-2010 |
| 20100286167 | DIHYDROXYPHENYL ISOINDOLYLMETHANONES - This invention provides methods for treating cancer, particularly hematopoietic tumors of lymphoid or myeloid lineage, prostate cancer, lung cancer, gastrointestinal stromal tumor, breast cancer and melanoma, which comprise administering to the mammal a compound, salt, hydrate, tautomer or N-oxide according to formula (I): | 11-11-2010 |
| Patent application number | Description | Published |
|---|
| 20080200354 | BREAKER AND DISPLACEMENT FLUID AND METHOD OF USE - A method of cleaning a wellbore prior to the production of oil or gas is disclosed, wherein the wellbore has been drilled with an invert emulsion drilling mud that forms an invert emulsion filter cake. The method may include the steps of circulating a breaker fluid into the wellbore, where the breaker fluid includes an aqueous fluid, and imino diacetic acid or salt thereof. Optionally an acid buffering agent, and a weighting age are also included. The breaker fluid is formulated such that after a predetermined period of time and the filter cake present in the wellbore or on the wellbore face is substantially degraded. Other methods may also include drilling the wellbore with a water-based drilling mud that forms a water-based filter cake, wherein the method may include the steps of circulating a breaker fluid into the wellbore, where the breaker fluid may include an aqueous fluid, and an iminodiacetic acid or a salt thereof. | 08-21-2008 |
| 20100212896 | GRAVEL-PACKING CARRIER FLUID WITH INTERNAL BREAKER - A method of gravel packing a hole in a subterranean formation having a filter cake coated on the surface thereof that includes injecting into the hole a gravel pack composition comprising gravel and a carrier fluid comprising a base fluid and at least one iminodiacetic acid or salt thereof is disclosed. | 08-26-2010 |
| 20100270017 | DELAYED BREAKER - A process that includes pumping a first wellbore fluid comprising an oxidative degradable polymer into a wellbore through a subterranean formation; pumping a second wellbore fluid comprising a pH-activated oxidative breaker into the wellbore; pumping a third wellbore fluid comprising a delayed acid source into the wellbore; and allowing the delayed acid source to acidify at least a portion of the wellbore to a pH of less than 7 so as to activate the pH-activated oxidative breaker at the lower pH and degrade the oxidative degradable polymers is disclosed. | 10-28-2010 |
