Patent application number | Description | Published |
20100173340 | USE OF HEMATOPOIETIC GROWTH FACTOR INDUCIBLE NEUROKININ-1 (HGFIN) AS A NOVEL BIOMARKER - The invention provides, in certain embodiments, a method of detecting an indicator of renal injury or renal disease. The method entails assaying a urine sample for hematopoietic growth factor inducible neurokinin-1 (HGFIN), wherein the presence of HGFIN at an elevated level indicates the presence and/or degree of renal injury or renal disease, and/or the rate of loss of renal function. In other embodiments, the invention provides a method of detecting an indicator of systemic inflammation. This method entails assaying a biological sample for HGFIN, wherein the presence of HGFIN at an elevated level indicates the presence and/or degree of systemic inflammation. Also provided, are methods of determining progression of these conditions, as well as methods of determining subjects' response to treatment. | 07-08-2010 |
20110177613 | Use of periostin as a novel biomarker - The invention provides, in certain embodiments, a method of detecting an indicator of renal injury or renal disease. The method entails assaying a urine sample for periostin, wherein the presence of periostin at an elevated level indicates the presence and/or degree of renal injury or renal disease. Also provided, are methods of determining progression of these conditions, as well as methods of determining subjects' response to treatment. | 07-21-2011 |
20120329886 | USE OF PERIOSTIN AS A NOVEL BIOMARKER - The invention provides, in certain embodiments, a method of detecting an indicator of renal injury or renal disease. The method entails assaying a urine sample for periostin, wherein the presence of periostin at an elevated level indicates the presence and/or degree of renal injury or renal disease. Also provided, are methods of determining progression of these conditions, as well as methods of determining subjects' response to treatment. | 12-27-2012 |
20130303563 | TREATMENT OF PERITONEAL INJURY USING JAK INHIBITORS - The invention provides, in certain embodiments, a method of preventing and/or treating peritoneal injury and/or diminished function by administering an effective amount of one or more inhibitors of JAK. The invention also provides a pharmaceutical composition including a JAK inhibitor for the treatment of peritoneal injury and/or diminished function. In another aspect, the invention provides a method of detecting an indicator of peritoneal injury. The method entails assaying a biological sample for periostin, wherein the presence of periostin at an elevated level indicates the presence and/or degree of peritoneal injury. Also provided, are methods of identifying subject for treatment of peritoneal injury and/or diminished function, methods of determining progression of these conditions, as well as methods of determining subjects' response to treatment. | 11-14-2013 |
20130344511 | USE OF HEMATOPOIETIC GROWTH FACTOR INDUCIBLE NEUROKININ-1 (HGFIN) AS A NOVEL BIOMARKER - The invention provides, in certain embodiments, a method of detecting an indicator of renal injury or renal disease. The method entails assaying a urine sample for hematopoietic growth factor inducible neurokinin-1 (HGFIN), wherein the presence of HGFIN at an elevated level indicates the presence and/or degree of renal injury or renal disease, and/or the rate of loss of renal function. In other embodiments, the invention provides a method of detecting an indicator of systemic inflammation. This method entails assaying a biological sample for HGFIN, wherein the presence of HGFIN at an elevated level indicates the presence and/or degree of systemic inflammation. Also provided, are methods of determining progression of these conditions, as well as methods of determining subjects' response to treatment. | 12-26-2013 |
20140135227 | USE OF PERIOSTIN AS A NOVEL BIOMARKER - The invention provides, in certain embodiments, a method of detecting an indicator of renal injury or renal disease. The method entails assaying a urine sample for periostin, wherein the presence of periostin at an elevated level indicates the presence and/or degree of renal injury or renal disease. Also provided, are methods of determining progression of these conditions, as well as methods of determining subjects' response to treatment. | 05-15-2014 |
Patent application number | Description | Published |
20100291915 | MODULAR CIRCUIT ARRANGEMENT USED FOR ATTENUATION COMPENSATION - The invention relates to a multi-band, multi-part circuit arrangement for compensating the attenuation of HF wireless signals in the signal paths between a transmitting and receiving device and an external antenna. The circuit arrangement comprises power amplifiers, receiving amplifiers, at least one splitter, at least one combiner, duplexers and frequency and/or band filters, HF switching means as well as a detector circuit for the detection of transmission signals from the transmitting and receiving device and for providing control signals for the HF switching means. It consists of a universal front-end module with HF switching means disposed on the antenna side for switching the signal paths on the antenna side, a broadband receiving amplifier and at least one splitter dividing the output signal of the receiving amplifier to several outputs of the front-end module, as well as a universal back-end module with HF switching means which is disposed on the device side and which is coupled with the transmitting and receiving device via the detector circuit for switching the signal paths on the device side, at least one receiving amplifier and at least one combiner, bringing together the input signals of several inputs of the back-end module. The front-end and the back-end modules can be combined and wired differently with various power amplifiers and different frequency and/or band filters. | 11-18-2010 |
20110116422 | RADIO TRANSMISSION SIGNAL DETECTION CIRCUIT - A detection circuit has a detector unit for detecting a transmitted signal from a mobile radio terminal. The detection circuit forms a part of a circuit arrangement for processing or influencing received signals and transmitted signals associated with the mobile radio terminal (accessory circuit). It is involved in the accessory circuit via a switching means, which is arranged in a transmission path upstream of at least one transmission power amplifier which can be activated upon detection of a transmitted signal, and is coupled to the transmission path via a coupling element which is arranged downstream of the transmission power amplifier. At the start of the transmission burst, the whole power of the transmitted signal is first of all supplied to the detector unit before said detector unit changes over the transmitted signal to the transmission power amplifier by operating the switching means. The detection circuit has a self-hold function, so that the detector unit leaves the accessory circuit in its operating state which is provided for the presence of a transmitted signal, even after the switching means has been changed over, at least until the transmission power amplifier has completed the circuit and the component of the amplified transmitted signal which is coupled out by means of the coupling element is applied to the detector unit. | 05-19-2011 |
20120170519 | METHOD FOR CONNECTING SIGNAL PATHS, AND FUNCTION GROUP DESIGNED THEREFOR - A method and system for connecting signal paths in a circuit arrangement with multiband capability for processing and/or influencing signals in radio communication, on the basis of which at least the transmission paths of a corresponding circuit arrangement are activated or deactivated on the basis of the presence of a transmitted signal from a terminal which is operated with the circuit arrangement. The transmission paths, which are deactivated in a basic state of the circuit arrangement, are periodically checked in succession for the presence of a transmitted signal from the terminal with a multiplexer that forms a functional component of a detection unit and that is switched through by a controller for sequential scanning of the transmission paths for the presence of such a transmitted signal. If a signal is present, only a transmission path for the correct frequency band of the transmitted signal is activated and continuously checked for the presence of a transmitted signal. | 07-05-2012 |
20130045695 | TRANSMITTING AND RECEIVING RADIO SIGNALS IN VARIOUS FREQUENCY RANGES - A device transmits and receives radio signals, in particular radio signals in a cellular radio network. The device contains a first transmitting antenna for transmitting radio signals and a second receiving antenna. The antennas transmit and/or receive radio signals in different frequency ranges. The antennas are connected to a common cable connection via a radio signal splitter, by which cable connection the device can be connected to a radio terminal. The device contains a first radio signal amplifier disposed in a first radio signal path and/or a second radio signal amplifier disposed in a second radio signal path. The transmitting antenna and the receiving antenna have attenuation with respect to feedback of a radio signal transmitted from the transmitting antenna to the receiving antenna due to the arrangement thereof relative to each other and due to the transmitting and/or receiving characteristics thereof. | 02-21-2013 |