Napp
Christian Napp, Hamburg DE
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20150053820 | Line System for an Aircraft and Aircraft with a Line System - A line system for an aircraft comprises at least one double-walled fluid line with an outer line body, an inner line body arranged therein and at least one spacer. The outer line body and the inner line body are fluid-tight, wherein the inner line body is realized in one piece of a flexible material. The at least one spacer is arranged on at least one of the inner line body and the outer line body in order to space apart and/or electrically insulate the inner line body and the outer line body. | 02-26-2015 |
Malte I. Napp US
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20100198208 | DIAGNOSTIC CATHETERS, GUIDE CATHETERS, VISUALIZATION DEVICES AND CHORD MANIPULATION DEVICES, AND RELATED KITS AND METHODS - Described herein are devices, methods and kits for assessing and/or enhancing the accessibility of a subvalvular space of a heart, accessing the subvalvular space of the heart (e.g., to provide access for one or more other devices), and/or positioning one or more devices in the subvalvular space of the heart. The devices described herein may, for example, comprise catheters that may be used to manipulate one or more chordae tendineae, diagnostic catheters having different sizes and/or shapes (e.g., different curvatures), guide catheters having different sizes and/or shapes (e.g., different curvatures), and visualization catheters. In some variations, the devices, methods, and/or kits may be used to visualize a target site, such as a subannular groove of a heart valve. In certain variations, the devices, methods, and/or kits may be used to manipulate chordae tendineae to provide additional space in a ventricle of a heart (e.g., enhancing the accessibility of the ventricle). | 08-05-2010 |
Matthias Napp, Loerrach DE
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20110046397 | NEW PROCESSES - The invention relates to a new process for producing NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone. In detail, the new processes, according to the present invention, are ultimately related to the synthesis of intermediates to prepare the above NEP inhibitors, namely compounds according to formula (1), or salt thereof, | 02-24-2011 |
20140243546 | Processes - The invention relates to a new process for producing NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone. In detail, the new processes, according to the present invention, are ultimately related to the synthesis of intermediates to prepare the above NEP inhibitors, namely compounds according to formula (1), or salt thereof, | 08-28-2014 |
Matthias Napp, Lorrach DE
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20100113801 | Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid - The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, | 05-06-2010 |
20120142916 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID - The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, | 06-07-2012 |
Matthias Napp, Basel CH
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20110112121 | Pharmaceutical Compositions and Solid Forms - The present invention relates to pharmaceutical compositions of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide, to the use of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide and compositions of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide in therapeutic applications, especially indications with a dysregulation/overexpression of VEFG, (neo)-vascularisation and VEGF driven angiogenesis and to methods for manufacturing such compositions, the invention further relates to specific forms of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide and to the manufacturing and use of such forms. The present invention also relates to a new process to produce 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide. | 05-12-2011 |
Matthias Napp, Lorrach CH
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20140249320 | Process for Preparing 5-biphenyl-4-amino-2-methyl Pentanoic Acid - The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, | 09-04-2014 |