Patent application number | Description | Published |
20120037360 | ACTUATORS AND RELATED METHODS - Various embodiments of the present invention disclose enhanced and improved well production tools for increasing the stability of production zones in a wellbore. Various embodiments of the present invention generally relate to apparatuses, systems, and processes for efficiently and effectively isolating zones within a wellbore. | 02-16-2012 |
20120037380 | FRACTURE VALVE TOOLS AND RELATED METHODS - Various embodiments of the present invention disclose enhanced and improved well production tools for increasing the stability of production zones in a wellbore. Various embodiments of the present invention generally relate to apparatuses, systems, and processes for efficiently and effectively isolating zones within a wellbore. | 02-16-2012 |
20120043092 | BLAPPER VALVE TOOLS AND RELATED METHODS - Various embodiments of the present invention disclose enhanced and improved well production tools for increasing the stability of production zones in a wellbore. Various embodiments of the present invention generally relate to apparatuses, systems, and processes for efficiently and effectively isolating zones within a wellbore. | 02-23-2012 |
20120085547 | PROCESSES AND SYSTEMS FOR TREATING OIL AND GAS WELLS - Systems and processes are provided for removing fluid from a subterranean well and enhancing the production of oil and/or gas are herein disclosed. In one embodiment, the system includes an injection conduit, an injection valve, a relief valve, a container, a container valve, a return conduit valve, and a return conduit, all arranged within a subterranean well for removing at least one fluid from the well. The removal of at least one fluid from the well is controlled by the flow of gas into the injection conduit. | 04-12-2012 |
20120273210 | PROCESSES AND SYSTEMS FOR TREATING OIL AND GAS WELLS - Systems and processes are provided for removing fluid from a subterranean well and enhancing the production of oil and/or gas are herein disclosed. In one embodiment, the system includes an injection conduit, an injection valve, a relief valve, a container, a container valve, a return conduit valve, and a return conduit, all arranged within a subterranean well for removing at least one fluid from the well. The removal of at least one fluid from the well is controlled by the flow of gas into the injection conduit. | 11-01-2012 |
Patent application number | Description | Published |
20100035248 | SURFACE-BASED NUCLEIC ACID ASSAYS EMPLOYING MORPHOLINOS - The sequence determination, detection, and quantification of nucleic acid molecules through sequence-specific binding (hybridization) on a solid support, specifically when Morpholinos are used as the surface-immobilized probe species in surface-based nucleic acid assays, and the assays as disclosed herein. | 02-11-2010 |
20100187133 | CAPACITIVE MORPHOLINO DIAGNOSTICS FOR ANALYSIS OF NUCLEIC ACIDS - Surface hybridization, a reaction in which nucleic acid molecules in solution react with nucleic acid partners immobilized on a surface, is widely practiced in life science research. In these applications the immobilized partner, or “probe”, is typically single-stranded DNA. Because DNA is strongly charged, high salt conditions are required to enable binding between analyte nucleic acids (“targets”) in solution and the DNA probes. High salt, however, compromises prospects for label-free monitoring or control of the hybridization reaction through surface electric fields, as well as stabilizes secondary structure in target species that can interfere with probe-target recognition. In this work, initial steps toward addressing these challenges are taken by introducing Morpholinos, a class of uncharged DNA analogues, for surface-hybridization applications. Monolayers of Morpholino probes on gold supports can be fabricated with methods similar to those employed with DNA, and are shown to hybridize efficiently and sequence-specifically with target strands. Hybridization-induced changes in the interfacial charge organization are analyzed with electrochemical methods and compared for Morpholino and DNA probe monolayers. Molecular mechanisms connecting surface hybridization state to the interfacial capacitance are identified and interpreted through comparison to numerical Poisson-Boltzmann calculations. Interestingly, positive as well as negative capacitive responses (contrast inversion) to hybridization are possible, depending on surface populations of mobile ions as controlled by the applied potential. Quantitative comparison of surface capacitance with target coverage (targets/area) reveals a near-linear relationship, and demonstrates sensitivities (limits of quantification) in the pg mm | 07-29-2010 |
20120211375 | CAPACITIVE MORPHOLINO DIAGNOSTICS FOR ANALYSIS OF NUCLEIC ACIDS - Use of Morpholinos, a class of uncharged DNA analogues, for surface-hybridization applications. Monolayers of Morpholino probes on gold supports are fabricated with methods similar to those employed with DNA, and are used to hybridize efficiently and sequence-specifically with target strands. Hybridization-induced changes in the interfacial charge organization are analyzed with electrochemical methods and compared for Morpholino and DNA probe monolayers. Molecular mechanisms connecting surface hybridization state to the interfacial capacitance are identified and interpreted through comparison to numerical Poisson-Boltzmann calculations. Positive as well as negative capacitive responses (contrast inversion) to hybridization are possible, depending on surface populations of mobile ions as controlled by the applied potential. Quantitative comparison of surface capacitance with target coverage (targets/area) reveals a near-linear relationship, and demonstrates sensitivities (limits of quantification) in the pg mm | 08-23-2012 |