Patent application number | Description | Published |
20080267985 | Variants of Group 1 Allergens from Poaceae Having Reduced Allergenicity and Maintained T-Cell Reactivity - The present invention relates to the preparation and use of variants of the group 1 allergens of the Poaceae (sweet grasses) which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially maintained reactivity with T-lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventive immunotherapy of grass pollen allergies. | 10-30-2008 |
20100158955 | Phl p 5a derivatives having reduced allergeneity and retained t-cell reactivity - The present invention relates to the preparation and use of variants of the group 5 allergen of the Pooideae which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially retained reactivity with T lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventative immunotherapy of grass pollen allergies. | 06-24-2010 |
20100310472 | DNA SEQUENCE, AND RECOMBINANT PREPARATION OF THE GRASS POLLEN ALLERGEN LOL P 4 - The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies. | 12-09-2010 |
20110104209 | DNA SEQUENCE, AND RECOMBINANT PREPARATION OF THE GRASS POLLEN ALLERGEN LOL P4 - The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies. | 05-05-2011 |
20120288526 | DNA SEQUENCE AND PREPARATION OF GRASS POLLEN ALLERGEN PHL P4 BY RECOMBINANT METHODS - The present invention relates to the provision of the genetic sequence of the major grass pollen allergen Phl p 4. The invention covers fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for the in vitro and in vivo diagnosis of pollen allergies. | 11-15-2012 |
20130164313 | DNA SEQUENCE, AND RECOMBINANT PREPARATION OF GROUP 4 MAJOR ALLERGENS FROM CEREALS - The present invention relates to the provision of DNA sequences of group 4 major allergens from cereals. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies. | 06-27-2013 |
20130224251 | VARIANTS OF GROUP 6 ALLERGENS OF THE TRUE GRASSES HAVING REDUCED ALLERGENEITY DUE TO MUTAGENESIS OF PROLINE RESIDUES - The present invention relates to the preparation and use of recombinant variants of group 6 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes. | 08-29-2013 |
20140255434 | PHL P 5A DERIVATIVES HAVING REDUCED ALLERGENEITY AND RETAINED T-CELL REACTIVITY - The present invention relates to the preparation and use of variants of the group 5 allergen of the Pooideae which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially retained reactivity with T lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventative immunotherapy of grass pollen allergies. | 09-11-2014 |
20150056229 | DNA SEQUENCE, AND RECOMBINANT PREPARATION OF THE GRASS POLLEN ALLERGEN LOL P 4 - The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies. | 02-26-2015 |
20150071953 | VARIANTS OF GROUP 6 ALLERGENS OF THE TRUE GRASSES HAVING REDUCED ALLERGENEITY DUE TO MUTAGENESIS OF PROLINE RESIDUES - The present invention relates to the preparation and use of recombinant variants of group 6 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes. | 03-12-2015 |
20150079120 | DNA SEQUENCE AND PREPARATION OF GRASS POLLEN ALLERGEN PHL P4 BY RECOMBINANT METHODS - The present invention relates to the preparation and use of recombinant variants of group 6 allergens of the | 03-19-2015 |
20150140024 | VARIANTS OF GROUP 5 ALLERGENS OF THE TRUE GRASSES HAVING REDUCED ALLERGENEITY DUE TO MUTAGENESIS OF PROLINE RESIDUES - The present invention relates to the preparation and use of recombinant variants of group 5 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes. | 05-21-2015 |
Patent application number | Description | Published |
20130125098 | Transformation of Computer Programs - A method and system to transform a plurality of programs associated with a plurality of programming languages is provided. In the method, a request is received by a computer to transform a first program in a first programming language to a second program in a second programming language. The first program is then transformed, wherein the transformation includes eliminating errors using predefined criteria. Further, the method maps a statement of the first program with a corresponding statement of the second program. | 05-16-2013 |
20140325491 | TRANSFORMATION OF COMPUTER PROGRAMS AND ELIMINATING ERRORS - A method and system for transforming a first computer program having program statements to a second computer program. A parsed first computer program is translated to the second computer program. The first computer program includes a first program statement that includes a first error. The translating includes: (i) identifying a second program statement in the parsed first computer program that includes a second error and has thrown a translation exception with respect to the second error, (ii) rolling back the translating to a predefined check point prior to the second program statement in the parsed first computer program such that the predefined check point is associated with a statement in the parsed first computer program that was successfully translated, and (iii) generating an executable equivalent translation for the second statement. After the translating, a mapping of one or more statements is generated. | 10-30-2014 |
20140358820 | COMPUTER ASSISTED CLASSIFICATION OF PACKAGED APPLICATION OBJECTS AND ASSOCIATED CUSTOMIZATIONS INTO A BUSINESS PROCESS HIERARCHY - Methods and arrangements for providing classification for a business process hierarchy. Packaged application objects are received, comprising at least one of the standard application objects and custom objects. At least one of the standard application objects is mapped to at least one node of a business process hierarchy, thereby forming at least one mapping template. At least one of the standard application objects is mapped to at least one of the custom objects to create a first mapping, and at least one of the custom objects is mapped to at least one of the standard application objects to create a second mapping. The at least one mapping template, the first mapping and the second mapping are combined, to create a mapping of at least one of the custom objects to the business process hierarchy. Other variants and embodiments are broadly contemplated herein. | 12-04-2014 |
Patent application number | Description | Published |
20090316602 | Method and System for Network Topology Discovery - Methods and apparatus for topology discovery of a network having heterogeneous network devices are disclosed. A network appliance communicates with the network devices to acquire device descriptors and characterize the network devices accordingly. Topology discovery is based on device characteristics, media-access data, and encoded connectivity patterns, where each connectivity pattern is defined by devices of specific device types and respective media-access data. A topology deduction module of the network appliance synthesizes a network image starting with unconnected devices and progressively incorporating detected connectivity patterns. | 12-24-2009 |
20100091664 | REAL-TIME NETWORK ANALYZER - A real-time network-analysis system comprises a network appliance and a plurality of management devices. The network appliance continuously monitors an object network and synthesizes a current network image comprising contemporaneous indicators of connectivity, occupancy, and performance of the object network. A management-client device may gain access to the network image for timely control and for use in producing long-term network-evolution plans. To enable the creation of a real-time network image, optimized topology synthesis algorithms are devised to minimize the computational effort. The real-time network-analysis system is adapted for use with an object network employing a variety of routing protocols, such as link-state protocols, and network-management protocols, such as the Simple-Network-Management protocol. | 04-15-2010 |
20120213215 | MOBILE STATION TRAFFIC ROUTING - Devices, networks and methods relating to routing gateway traffic in a mesh network for wireless access. A mesh network has multiple nodes in at least one gateway node through which all incoming and outgoing data traffic pass through. The nodes provide wireless access to wireless and user devices, each of which is associated with anode in the mesh network. Each gateway node contains a record detailing which nodes are providing wireless access to which wireless end user device and which nodes are associated with which end user devices. This record of each end user device's location is periodically updated as the gateway node periodically receives data from the nodes which detail the device is being serviced by which node. Any incoming data traffic destined for an end user device is encapsulated and routed to the proper node servicing that end user device. | 08-23-2012 |
20150120856 | METHOD AND SYSTEM FOR PROCESSING NETWORK TRAFFIC FLOW DATA - Network traffic flow records received from a network probe are recorded in multiple sets of buckets of different granularity, optimized for the purpose of almost instant analysis and display as well as for longer term report generation. The flow data is pre-processed and stored redundantly in parallel in multiple bucketized data base tables of different time window sizes. Denormalized tables keyed on different combinations of traffic flow attributes are precomputed and stored in parallel tables redundantly to facilitate a near real time display of summarized network traffic data, and a capability to rapidly generate reports for different monitoring periods. | 04-30-2015 |
20150120959 | METHOD AND SYSTEM FOR MONITORING AND ANALYSIS OF NETWORK TRAFFIC FLOWS - Network traffic flow records received from a network probe are filtered and short traffic flows are selected so that the total number of short traffic flows is high but the number of bytes in the short traffic flows is negligible, followed by discarding of the short traffic flows. Traffic flow data is recorded in multiple sets of buckets of different granularity, optimized for the purpose of almost instant analysis and display as well as for longer term report generation. The traffic flow data is pre-processed and stored redundantly in parallel in multiple bucketized data base tables of different time window sizes. A corresponding method and system are provided. | 04-30-2015 |
Patent application number | Description | Published |
20140348345 | VAD DETECTION MICROPHONE AND METHOD OF OPERATING THE SAME - A microphone includes a microelectromechanical system (MEMS) circuit and an integrated circuit. The MEMS circuit is configured to convert a voice signal into an electrical signal, and the integrated circuit is coupled to the MEMS circuit and is configured to receive the electrical signal. The integrated circuit and the MEMS circuit receive a clock signal from an external host. The clock signal is effective to cause the MEMS circuit and integrated circuit to operate in full system operation mode during a first time period and in a voice activity mode of operation during a second time period. The voice activity mode has a first power consumption and the full system operation mode has a second power consumption. The first power consumption is less than the second power consumption. The integrated circuit is configured to generate an interrupt upon the detection of voice activity, and send the interrupt to the host. | 11-27-2014 |
20150043755 | VAD DETECTION MICROPHONE AND METHOD OF OPERATING THE SAME - A microphone includes a microelectromechanical system (MEMS) circuit and an integrated circuit. The MEMS circuit is configured to convert a voice signal into an electrical signal, and the integrated circuit is coupled to the MEMS circuit and is configured to receive the electrical signal. The integrated circuit and the MEMS circuit receive a clock signal from an external host. The clock signal is effective to cause the MEMS circuit and integrated circuit to operate in full system operation mode during a first time period and in a voice activity mode of operation during a second time period. The voice activity mode has a first power consumption and the full system operation mode has a second power consumption. The first power consumption is less than the second power consumption. The integrated circuit is configured to generate an interrupt upon the detection of voice activity, and send the interrupt to the host. | 02-12-2015 |
20150055799 | Synchronization of Buffered Data in Multiple Microphones - First analog signals are received from a first microphone, converted into first digital data and stored in a first buffer. A determination is made as to whether voice activity has occurred when voice activity is determined, a voice activity detect signal is sent to an external processor. The external processor responsively provides an exterior clock signal upon receiving the voice activity detect signal. Second analog signals are received from a second microphone, converted into second digital data and stored in a second buffer. The first digital data in the first buffer is not necessarily synchronized in real time with the second digital data in the second buffer. The first digital data from the first buffer and the second digital data from the second buffer is decimated using the external clock to provide decimated output data, the decimated output data having the first digital data and the second digital data aligned in real time. | 02-26-2015 |
20150055803 | Decimation Synchronization in a Microphone - An external clock signal having a first frequency is received. A division ratio is automatically determined based at least in part upon a second frequency of an internal clock. The second frequency is greater than the first frequency. A decimation factor is automatically determined based at least in part upon the first frequency of the external clock signal, the second frequency of the internal clock signal, and a predetermined desired sampling frequency. The division ratio is applied to the internal clock signal to reduce the first frequency to a reduced third frequency. The decimation factor is applied to the reduced third frequency to provide the predetermined desired sampling frequency. Data is clocked to a buffer using the predetermined desired sampling frequency. | 02-26-2015 |
20150112689 | Acoustic Activity Detection Apparatus And Method - Streaming audio is received. The streaming audio includes a frame having plurality of samples. An energy estimate is obtained for the plurality of samples. The energy estimate is compared to at least one threshold. In addition, a band pass estimate of the signal is determined. An energy estimate is obtained for the band-passed plurality of samples. The two energy estimates are compared to at least one threshold each. Based upon the comparison operation, a determination is made as to whether speech is detected. | 04-23-2015 |
20150120299 | VAD Detection Apparatus and Method of Operating the Same - At a processing device, a first signal from a first microphone and a second signal from a second microphone are received. The first signal indicates whether a voice signal has been determined at the first microphone, and the second signal indicates whether a voice signal has been determined at the second microphone. When the first signal indicates potential voice activity or the second signal indicates potential voice activity, the processing device is activated to receive data and the data is examined for a trigger word. When the trigger word is found, a signal is sent to an application processor to further process information from one or more of the first microphone and the second microphone. When no trigger word is found, the processing device is reset to deactivate data input and allowing the first microphone and the second microphone to enter or maintain an event detection mode of operation. | 04-30-2015 |
Patent application number | Description | Published |
20100016347 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS - The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin. | 01-21-2010 |
20120245393 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES - Compounds of structure (I): | 09-27-2012 |
20130209383 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS - The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin. | 08-15-2013 |
20140235899 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES - Compounds of structure (I): | 08-21-2014 |
20140363388 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS - The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin. | 12-11-2014 |
Patent application number | Description | Published |
20110062983 | REDUCING SWITCHING NOISE - Described herein are various principles for operating a transmitter circuit to reduce noise affecting a signal being generated and reducing jitter. In some embodiments, a circuit is operated in a way that switching occurs at or above a bit rate of transmission, such that at least one switch changes state at least for every bit. Operating the circuit in such a way leads to a switching rate that is above a resonant frequency of the circuit and prevents large oscillations and noise from being inserted into the signal and causing communication problems. | 03-17-2011 |
20110115561 | OUTPUT COMMON MODE VOLTAGE STABILIZER OVER LARGE COMMON MODE INPUT RANGE IN A HIGH SPEED DIFFERENTIAL AMPLIFIER - A circuit includes a differential amplifier having a folded cascode architecture with a pair of cascode transistors. A sensing circuit senses a common mode input voltage of a differential input signal applied to the differential amplifier. A bias generator circuit generates a bias voltage for application to the pair of cascode transistors in the folded cascode architecture. The bias generator circuit is connected to an output of the sensing circuit such that the generated bias voltage has a value which is dependent on the sensed common mode input voltage. This dependence stabilizes a common mode output voltage from the differential amplifier in response to changes in the common mode input voltage. | 05-19-2011 |
20120099832 | PORTABLE VIDEO PLAYER - A portable video player includes: a data input coupled to a memory module to store at least one video file, a video decoder coupled to the memory module via a memory interface to decode the video file, and a video interface connector to output to a display the decoded video file. | 04-26-2012 |
20120169403 | POWER HARVESTING IN OPEN DRAIN TRANSMITTERS - A transmitter having at least one channel comprising a first differential circuit driven by a differential data signal, the first differential circuit configured to output the differential data at a first and second output and a first control circuit coupled between the first differential circuit and the first and second output, the first control circuit driven by a drive voltage. | 07-05-2012 |
20120169438 | HDMI RECEIVER - An embodiment of a transmitter includes an amplifier having first and second differential output nodes, a first supply node, a first pull-up impedance having a first node coupled to the first differential output node and having a second node coupled to the supply node, and a second pull-up impedance having a first node coupled to the second differential output node and having a second node coupled to the supply node. An embodiment of a receiver includes an amplifier having first and second differential input nodes, a first supply node, a first pull-up impedance having a first node coupled to the first differential input node and having a second node coupled to the supply node, and a second pull-up impedance having a first node coupled to the second differential input node and having a second node coupled to the supply node. In an embodiment, the transmitter and receiver are capacitively coupled to one another. | 07-05-2012 |
20130127537 | OUTPUT COMMON MODE VOLTAGE STABILIZER OVER LARGE COMMON MODE INPUT RANGE IN A HIGH SPEED DIFFERENTIAL AMPLIFIER - A circuit includes a differential amplifier having a folded cascode architecture with a pair of cascode transistors. A sensing circuit senses a common mode input voltage of a differential input signal applied to the differential amplifier. A bias generator circuit generates a bias voltage for application to the pair of cascode transistors in the folded cascode architecture. The bias generator circuit is connected to an output of the sensing circuit such that the generated bias voltage has a value which is dependent on the sensed common mode input voltage. This dependence stabilizes a common mode output voltage from the differential amplifier in response to changes in the common mode input voltage. | 05-23-2013 |
20140292402 | SYNCLESS UNIT INTERVAL VARIATION TOLERANT PWM RECEIVER CIRCUIT, SYSTEM AND METHOD - A PWM receiver circuit receives and demodulates pulse width modulated (PWM) data signals without requiring synchronization such that no synchronization preamble need be provided with the PWM data signal. Embodiments may consume less power since there is no need to repeatedly synchronize a PLL, counter or other circuitry to the PWM data signal. Furthermore, the PWM receiver circuit operates in view of or is “tolerant” to jitter in the frequency of the PWM signal and also to a relatively wide range of intentional variation in the frequency. Interleaved operation of parallel PWM receiver circuits are utilized in some embodiments. In one embodiment currents are integrated during low and high portions of the duty cycle of the PWM data signal and the difference in the respective voltages generated through such integration used to demodulate the PWM data signal. | 10-02-2014 |
20150280898 | OVERSAMPLING CDR WHICH COMPENSATES FREQUENCY DIFFERENCE WITHOUT ELASTICITY BUFFER - A method, algorithm, architecture, circuit and/or system that compensates for frequency difference in oversampled CDRs. The oversampled CDR uses a programmable divider whose division ratio is changed, for one or more cycles, from its usual division ratio, when accumulated phase movement in either direction exceeds a threshold. Accordingly, the elasticity buffer in oversampled CDRs can be made much smaller or entirely eliminated, resulting in less area, and reduced or eliminated dependence of max allowed burst size on ppm difference. The threshold can be kept programmable, and more than half unit interval, to provide robustness towards high frequency jitter. | 10-01-2015 |
20150341017 | AUTOMATIC POWER SWITCHING AND POWER HARVESTING IN THIN OXIDE OPEN DRAIN TRANSMITTER CIRCUITS, SYSTEMS, AND METHODS - A power harvesting circuit includes a new transmitter topology that ensures that no junction of thin oxide transistors forming the power harvesting circuit will experience a voltage across junctions of the transistors that is more than a maximum tolerable junction voltage. A supplemental power feed circuit operates to provide a supplemental feed current to components in a transmitter circuit when power harvested from a receiver circuit is insufficient to adequately power these components of the transmitter circuit, which may occur during high frequency operation of communications channels coupling the transmitter and receiver circuits. The supplemental power feed circuit also operates to sink a shunt current when power harvested from the receiver circuit is more than is needed to power the components in the transmitter circuit. | 11-26-2015 |