Patent application number | Description | Published |
20100021744 | SUBSTRATE FOR PRODUCING ORGANIC NANOCRYSTALS - Substrates for growing small crystals, the substrates having a first layer consisting of glass, polymer, and/or metal; a second layer having hydrophilic SAMs and hydrophobic SAMs, wherein the hydrophilic SAMs are located only on discrete islands on the first layer and the hydrophobic SAMs are located only on areas of the first layer free of hydrophilic SAMs. | 01-28-2010 |
20100021851 | METHODS FOR PRODUCING ORGANIC NANOCRYSTALS - Methods for producing small crystals on islands formed on specialized substrates by, inter alia, subjecting the substrate to a hydrophilic SAMs solution for self-assembling hydrophilic SAMs on certain portions of the substrate surface and subjecting the substrate to a hydrophobic SAMs solution for self-assembling hydrophobic SAMs on certain other portions of the substrate surface. | 01-28-2010 |
20100105907 | CONTINUOUS ANTISOLVENT CRYSTALLIZATION PROCESS AND SYSTEM USING PLUG FLOW REACTORS - A process and system for continuous crystallization of a compound using antisolvent addition in which a solution is prepared with an organic compound and a solvent. An antisolvent is added to the solution in a continuous plug flow system comprising at least one process module. The antisolvent can be added in multiple addition points such that the overall amount of antisolvent added to the continuous plug flow reactor remains fixed. The multiple addition point technique provides every process module with an equal volume of antisolvent. Finally, crystals are recovered from the slurry upon exiting the system. Preferably, the mean crystal size is less than 100 μm. | 04-29-2010 |
20100174111 | PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS - Disclosed herein is a process for purifying aryl carboxylic acids, in particular terephthalic acid, wherein the impure acid is dissolved or dispersed in an ionic liquid and a non-solvent is added to precipitate the purified acid. The present disclosure further relates to compositions comprising terephthalic acid and one or more ionic liquids. | 07-08-2010 |
20120058236 | SWEETENER COMPOSITION COMPRISING HIGH SOLUBILITY FORM OF REBAUDIOSIDE A AND METHOD OF MAKING - Disclosed are sweetener compositions comprising rebaudioside A and methods of making the sweetener compositions. The sweetener compositions comprise a highly soluble crystal form of rebaudioside A that displays, in some embodiments, a solubility at 24° C. in water of about 25 (grams rebaudioside A/per 100 grams water) or greater. The high solubility of the sweetener composition of the invention allows it to be used in applications such as syrups and concentrates. | 03-08-2012 |
20120289687 | METHODS TO TREAT MIXTURES OF GLYCOSIDES TO OBTAIN ONE OR MORE OF THESE GLYCOSIDES IN MORE PURE FORM - The present invention provides methods to treat mixtures containing natural rebaudioside A (Reb A), rebaudioside B (Reb B), and rebaudioside D (Reb D), synthetic counterparts of these, and/or derivatives of the natural or synthetic embodiments obtain one or more of these glycosides in more pure form. In many embodiments, the invention can be used to process glycoside mixtures obtained at least in part from natural sources such as the | 11-15-2012 |
20130068996 | PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS - Disclosed herein is a process for purifying aryl carboxylic acids, in particular terephthalic acid, wherein the impure acid is dissolved or dispersed in an ionic liquid and a non-solvent is added to precipitate the purified acid. The present disclosure further relates to compositions comprising terephthalic acid and one or more ionic liquids. | 03-21-2013 |
Patent application number | Description | Published |
20120076860 | COMPOSITIONS, METHODS, AND SYSTEMS RELATING TO CONTROLLED CRYSTALLIZATION AND/OR NUCLEATION OF MOLECULAR SPECIES - The present invention generally relates to compositions, methods, and systems relating to controlled crystallization and/or nucleation of a molecular species. In some embodiments, the crystallization and/or nucleation of the molecular species may be controlled by tuning the surface chemistry and/or the morphology of a crystallization substrate. In some embodiments, the molecular species is a small organic molecule (e.g., pharmaceutically active agent). | 03-29-2012 |
20120305174 | LAYER PROCESSING FOR PHARMACEUTICALS - Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet. | 12-06-2012 |
20130118399 | METHODS AND SYSTEMS RELATING TO THE SELECTION OF SUBSTRATES COMPRISING CRYSTALLINE TEMPLATES FOR THE CONTROLLED CRYSTALLIZATION OF MOLECULAR SPECIES - The present invention generally relates to methods and systems relating to the selection of substrates comprising crystalline templates for the controlled crystallization of molecular species. In some embodiments, the methods and systems allow for the controlled crystallization of a molecular species in a selected polymorphic form. In some embodiments, the molecular species is a small organic molecule (e.g., pharmaceutically active agent). | 05-16-2013 |
20130295143 | ELECTROPROCESSING OF ACTIVE PHARMACEUTICAL INGREDIENTS - Electrospinning of crystalline particles comprising active pharmaceutical ingredients (API) from suspensions yields fibrous compositions comprising the API. The morphology and size of the crystalline particles may be preserved. The particles may be predominantly retained by fibers and distributed throughout the fibrous mesh. Tablet forms of the APIs prepared from the fibrous compositions demonstrate higher dissolution rates than tablets prepared from compacted powders of the APIs. | 11-07-2013 |
20140256984 | DEVICES AND METHODS FOR CRYSTALLIZATION - The invention in some aspects relates to devices and methods for nucleating crystals under controlled conditions. In some aspects of the invention, devices and methods are provided for continuous crystallization. | 09-11-2014 |
20150196489 | POLYMER MATRICES FOR CONTROLLING CRYSTALLIZATION - Compositions, methods, and systems for controlling crystallization of an agent are generally described. In some embodiments, an agent is crystallized in the presence of polymer matrices, such as polymer particles. The polymer matrix may influence at least a portion of the crystallization process and/or the resulting composition. In some such embodiments, the polymer matrix allows one or more aspect of the process and/or composition to be controlled and/or altered. For instance, the polymer matrix may act as a crystallization promoter and/or acceptable carriers of the crystallized agent. In certain embodiments, the polymer matrix described herein, can be used with any agent regardless of its chemical and/or physical properties. | 07-16-2015 |
Patent application number | Description | Published |
20090138096 | FOOT/ANKLE IMPLANT AND ASSOCIATED METHOD - A foot/ankle implant anatomically-shaped for implantation between two bone portions of the foot or ankle to correct associated deformities. The foot/ankle implant has a peripheral wall surrounding a central bore therethrough and defining an annular cross-section. The wall is constructed from a composite material that includes a ceramic component and a polymer component. The ceramic component is gradually resorbed after implantation, and the polymeric component gradually degrades after implantation. | 05-28-2009 |
20110093017 | METHOD AND PLATE FOR FUSING THE MEDIAL COLUMN BONES OF THE FOOT - A method for joining together a first, a second and a third bone part of a surgical patient includes obtaining a bone plate having a first, a second and a third portion arranged along a longitudinal axis. The first portion contains a first slot for receiving a first compressing screw. The second portion is adjacent to the first portion and contains a second slot for receiving a second compressing screw. The third portion is adjacent to the second portion and contains a threaded hole for receiving a locking screw. The method further includes positioning the first, second and third portions over the first, second and third bone parts. The method further includes inserting the locking screw into the threaded hole and into the third bone part, inserting the second compressing screw into the second slot and into the second bone part, and inserting the first compressing screw into the first slot and into the first bone part, thereby urging the first, second and third bone parts together. | 04-21-2011 |
20110093018 | DORSAL MIDFOOT BONE PLATE SYSTEM AND METHOD - A bone plate system for joining together adjacent bone parts of a surgical patient includes a bone plate having a first slot defining a first centerline axis, a second slot defining a second centerline axis, and a third slot defining a third centerline axis. The first, second and third slots are disposed in a triangular arrangement and simultaneously positionable over each of three adjacent bone parts. Each of a first compressing screw, a second compressing screw and a third compressing screw has a threaded shank for passage through the first, second and third slots, respectively, and engagement into the underlying bone part. Each of the first, second and third compressing screws also has a screw head configured to forcefully interact during insertion until fully seated with the first, second and third slot, respectively, thereby urging the first, second and third compressing screws to move along the first, second and third centerline axis, respectively, such that the three bone parts are multi-axially compressed towards each other. | 04-21-2011 |
20120065689 | Joint Fusion Construct And Method - A construct for fusing a joint between a proximal bone and a distal bone comprises a plate body having a proximal end, a distal end, and a longitudinal axis extending between the proximal and distal ends; a rigid joint bridge on the plate body intermediate the proximal and distal ends, the bridge separating the plate body between a proximal bone portion and a distal bone portion; a plurality of screw receiving holes extending through the proximal bone portion of the plate, the distal most pair of the holes defining a first transverse axis at an oblique angle relative the longitudinal axis; a plurality of screw receiving holes extending through the distal bone portion of the plate, the proximal most pair of the holes defining a second transverse axis at an oblique angle relative the longitudinal axis; a plurality of screws extending through the holes and attaching the plate body to the proximal and distal bones; and a joint screw traversing the joint between the first and second transverse axes. | 03-15-2012 |
20140012328 | MIDFOOT BONE PLATE SYSTEM - A bone plate system is provided for joining together bone parts of a surgical patient. The system includes an elongated bone plate defining a longitudinal axis and having a first portion containing a first slot; a second portion containing a second slot; and a third portion containing a threaded hole. First and second compressing screws are provided for passage through the first and second slots and engagement into first and second respective bone parts. The compressing screws are configured to forcefully interact with the slots, and to urge the bone parts towards one another. A locking screw is provided for passage through the threaded hole and engagement into a third bone part. | 01-09-2014 |
20140094913 | Scaffold For Spring Ligament Repair - A construct is disclosed that may be used to repair or replace a natural ligament. The construct may be formed of materials for biocompatibility and/or resorbtion. The construct may be provided or connected to a soft anchor for connection to a bone portion. | 04-03-2014 |
20140277447 | Scaffold For Spring Ligament Repair - A construct is disclosed that may be used to repair or replace a natural ligament. The construct may be formed of materials for biocompatibility and/or resorbtion. The construct may be provided or connected to a soft anchor for connection to a bone portion. | 09-18-2014 |
Patent application number | Description | Published |
20080270369 | FRAMEWORK FOR PROVIDING METRICS FROM ANY DATASOURCE - A metrics generation system provides IT and other computing system metrics from different data sources in a single display. Configuration files containing parameters and instructions are loaded by the system to access different data sources. The metrics generation system retrieves IT system health data, processes and aggregates metrics from the retrieved data and displays the metrics based on user defined parameters and instructions in the configuration files. The metrics generation system is flexible in that it can be changed to extract data from different IT data sources, calculate different metric information having a hierarchy of attribute types and values, and display a variety of metric data in different formats. | 10-30-2008 |
20080270469 | BUSINESS METRICS AGGREGATED BY CUSTOM HIERARCHY - A metrics generation system provides IT computing system metrics that are aggregated by a custom hierarchy. The custom hierarchy is specified by a user through configuration files. The metrics generation system retrieves IT system health data, processes and aggregates metrics from the retrieved data and displays the metrics based on user defined parameters and instructions in the configuration files. The metrics generation system is flexible in that it can be changed to extract data from different IT data sources, calculate different metric information having a hierarchy of attribute types and values, and display a variety of metric data in different formats. | 10-30-2008 |
20080313628 | METRICS PACK DISTRIBUTION FOR DATA REPORTING TOOL - Systems and methods for implementing non-executable configuration files into a resource reporting application are disclosed. In accordance with one embodiment, a method for implementing non-executable configuration files into a resource reporting application includes developing one or more non-executable data files for implementation into the resource reporting application. The non-executable data files are then bundled into a file pack. The file pack is then distributed to the resource reporting application. The resource reporting application then implements one or more non-executable data files into the resource reporting application. In further embodiments, the non-executable data files include XML files. In some embodiments, the non-executable data files are bundled into a .cab file pack. | 12-18-2008 |
Patent application number | Description | Published |
20140287723 | Mobile Applications For Dynamic De-Identification And Anonymity - Various systems, computer-readable media, and computer-implemented methods of providing improved data privacy and security by enabling subjects to which data pertains to remain “dynamically anonymous,” i.e., anonymous for as long as is desired—and to the extent that is desired—are disclosed herein. Embodiments may include systems that create, access, use (e.g., by collecting, processing, copying, analyzing, combining, modifying or disseminating, etc.), store and/or erase data with increased privacy and security, thereby facilitating the availability of more qualified and accurate information. When data is authorized by subjects to be shared with third parties, embodiments may facilitate sharing information in a dynamically controlled manner that enables delivery of temporally-, geographically-, and/or purpose-limited information to the receiving party. In one example, mobile/wearable/portable applications implementing a system or aspects thereof as disclosed herein may provide a controlling entity with control over both the timing and level of participation in location- and time-sensitive applications. | 09-25-2014 |
Patent application number | Description | Published |
20150128284 | Dynamic De-Identification And Anonymity - Various systems, computer-readable media, and computer-implemented methods of providing improved data privacy, anonymity and security by enabling subjects to which data pertains to remain “dynamically anonymous,” i.e., anonymous for as long as is desired—and to the extent that is desired—are disclosed herein. Embodiments include systems that create, access, use, store and/or erase data with increased privacy, anonymity and security, thereby facilitating the availability of more qualified and accurate information. When data is authorized by subjects to be shared with third parties, embodiments may facilitate sharing information in a dynamically controlled manner that enables delivery of temporally-, geographically-, and/or purpose-limited information to the receiving party. In one example, anonymity measurement scores may be calculated for the shared data elements so that a level of consent/involvement required by the Data Subject before sharing the relevant data elements to third parties may be specified. | 05-07-2015 |
20150128285 | Dynamic De-Identification And Anonymity - Various systems, computer-readable media, and computer-implemented methods of providing improved data privacy, anonymity and security by enabling subjects to which data pertains to remain “dynamically anonymous,” i.e., anonymous for as long as is desired—and to the extent that is desired—are disclosed herein. Embodiments include systems that create, access, use, store and/or erase data with increased privacy, anonymity and security, thereby facilitating the availability of more qualified and accurate information. When data is authorized by subjects to be shared with third parties, embodiments may facilitate sharing information in a dynamically controlled manner that enables delivery of temporally-, geographically-, and/or purpose-limited information to the receiving party. In one example, anonymity measurement scores may be calculated for the shared data elements so that a level of consent/involvement required by the Data Subject before sharing the relevant data elements to third parties may be specified. | 05-07-2015 |
20150128287 | Dynamic De-Identification And Anonymity - Various systems, computer-readable media, and computer-implemented methods of providing improved data privacy, anonymity and security by enabling subjects to which data pertains to remain “dynamically anonymous,” i.e., anonymous for as long as is desired—and to the extent that is desired—are disclosed herein. Embodiments include systems that create, access, use, store and/or erase data with increased privacy, anonymity and security, thereby facilitating the availability of more qualified and accurate information. When data is authorized by subjects to be shared with third parties, embodiments may facilitate sharing information in a dynamically controlled manner that enables delivery of temporally-, geographically-, and/or purpose-limited information to the receiving party. In one example, anonymity measurement scores may be calculated for the shared data elements so that a level of consent/involvement required by the Data Subject before sharing the relevant data elements to third parties may be specified. | 05-07-2015 |
20150310560 | Systems And Methods For Improving Government Financing Of Infrastructure Services/Improvements - Disclosed herein are various categorization and rating systems for tax liens, tax deeds, and/or non-ad valorem (NAV) liens, as well as associated methods that facilitate classifications and ratings across various local governmental jurisdictions according to a common, referenceable categorization and/or rating scheme. The common categorization and/or rating scheme facilitates identification of tax liens, tax deeds and/or NAV liens having common underlying real property characteristics, investment characteristics, or other characteristics. In one example, a computer categorizes the tax liens, tax deeds and/or NAV liens into subgroups, and determines a rating based on one or more characteristics, including the likely desirableness as an investment vehicle to certain classes of investors. The categorized tax lien/tax deed and/or NAV lien information and the ratings may be made available to third-party computing devices (such as mobile devices or tablets) used by potential investors to evaluate the possible purchase thereof. | 10-29-2015 |
20150379303 | Systems And Methods For Contextualized Data Protection - Various systems, computer-readable media, and computer-implemented methods of providing improved data privacy, anonymity, and security by enabling subjects to which data pertains to remain “dynamically anonymous,” i.e., anonymous for as long as is desired—and to the extent that is desired—are disclosed herein. This concept is also referred to herein as Just-In-Time-Identity, or “JITI.” Embodiments include systems that create, access, use, store and/or erase data with increased privacy, anonymity and security—thereby facilitating the availability of more qualified information—via the use of temporally unique, dynamically changing de-identifiers (“DDIDs”). In some embodiments, specialized JITI keys may be used to “unlock” different views of the same DDID (or its underlying value), thereby providing granular control over the level of detail or obfuscation visible to each user based on the context of said user's authorized use of data, e.g., authorized purpose(s), place(s), time(s), or other attributes of the use. | 12-31-2015 |
Patent application number | Description | Published |
20100280939 | FINANCIAL DATA PROCESSING SYSTEM - A method of processing financial articles of trade is provided. The method includes collecting real time data from a plurality of liquidity destinations in trading at least one of securities, commodities, options, futures and derivatives, the real time data including information on submitted transactions of financial articles of trade. The real time data collected from the plurality of liquidity destinations is aggregated. The real time data is streamed in a standardized form. User criteria are established to identify relevant portions of the streamed real time data. The streamed real time data is analyzed according to the user criteria. The analyzed real time data is consolidated into a computer data base. | 11-04-2010 |
20110161220 | Method and System for Monitoring Financial Market Trading Activity to Establish and Track Aggregate Trading Limits Based on Trading Sub-Limits Assigned by Prime Brokers for Particular Trading Entities - The present invention relates to systems and methods for monitoring market transaction activity data to determine when a trading entity has exceeded an aggregated limit consisting of one or more trading sub-limits corresponding to one or more custodial prime brokers facilitating trading for the trading entity. The method includes collecting at a centralized hub real time data related to conditions of a trading market from one or more liquidity destinations trading at least one financial article of trade. Trading activity for a trading entity is determined. An aggregate trading limit is determined that is based on one or more trading sub-limits assigned by one or more prime brokers for that trading entity. It is determined when that trading activity exceeds the aggregate trading limit. | 06-30-2011 |
20110166982 | INTRADAY RISK MANAGEMENT DATA CLOUD COMPUTING SYSTEM CAPABLE OF CONTROLLING EXECUTION OF ORDERS - In at least one embodiment, a method and system associated with financial articles of trade may include comparing relevant portions of data pertaining to an attempted transaction, wherein the transaction may pertain to one in which an entity is financially liable but unaware. At least one embodiment includes monitoring market transaction activity data to determine when a trading entity has exceeded an aggregated limit, such as one or more trading sub-limits corresponding to one or more custodial prime brokers facilitating trading for the trading entity. At least one embodiment includes a pre-trade gateway to determine if an order violates a pre-trade risk based on information collected by a front-end analyzer. Possible actions include, but are not limited to, placing a null order, terminating a connection associated with the order, modifying the order so as not to violate a pre-trade risk check, and/or notifications to one or more entities. | 07-07-2011 |
20110202447 | Financial data processing system - To process financial articles of trade, real time data is collected from a plurality of liquidity destinations in trading at least one of securities, commodities, options, futures and derivatives, the real time data including information on submitted transactions of financial articles of trade. The real time data collected from the plurality of liquidity destinations is aggregated. The real time data is streamed in a standardized form. User criteria are established to identify relevant portions of the streamed real time data. The streamed real time data is analyzed according to the user criteria. The analyzed real time data is consolidated into a computer data base. | 08-18-2011 |
20120203682 | FINANCIAL DATA PROCESSING SYSTEM - To process financial articles of trade and manage risk, data messages originating from a plurality of sources arranged to trade at least one of securities, commodities, options, futures and derivatives are collected. The collected data including information on submitted transactions and completed transactions of financial articles of trade. The collected data is analyzed against established user criteria to identify select portions of the collected data. If a match is detected a risk alert signal will be transmitted. | 08-09-2012 |
20150187003 | METHOD AND SYSTEM FOR MANAGING INTRADAY RISK OVER A COMMUNICATIONS NETWORK - Example embodiments include a method and system for managing intraday risk conditions. Data transaction specific data messages transmitted over a data communications network from a plurality of source nodes trading an article of trade with a plurality of destination nodes are processed. The messages include account parameter information. Intraday risk condition data is associated in memory with entity identification data associated with an entity. Using the entity identification data, account parameter information included in the processed data transaction specific data messages is identified that matches the intraday risk condition data for the entity. In response to an identified match, a data transaction involving the entity submitted via a communication session to a corresponding one of the plurality of destination nodes is modified to reduce intraday risk for the entity associated with the data transaction. | 07-02-2015 |