Patent application number | Description | Published |
20090294017 | OPTICAL CONTACTING ENABLED BY THIN FILM DIELECTRIC INTERFACE - A method of assembling precision optical or optomechanical components of otherwise incompatible chemistry that provides first and second components having respective first and second polished contacting surfaces to be bonded; deposits a thin film dielectric coating at the surface of the first and or second polished surface, and contacts the coated portion of the first or second components with the respective contacting surfaces to be bonded, while maintaining alignment of the two components, to form a single structure. | 12-03-2009 |
20090294050 | OPTICAL CONTACTING ENHANCED BY HYDROXIDE IONS IN A NON-AQUEOUS SOLUTION - This invention is a method of assembling precision optical or optomechanical components that provides first and second components having respective first and second polished contacting surfaces to be bonded; generates a hydrophilic surface on at least a portion of at least one of the first or second surfaces; rinses the hydrophilic portion with water or another suitable solvent; and contacts the hydrophilic portion of the first or second components with the respective contacting surfaces to be bonded, while maintaining alignment of the two components, to form a single structure | 12-03-2009 |
20090294051 | OPTICAL CONTACTING ENABLED BY THIN FILM DIELECTRIC INTERFACE - A method of assembling precision optical or optomechanical components of otherwise incompatible chemistry that provides first and second components having respective first and second polished contacting surfaces to be bonded; deposits a thin film dielectric coating at the surface of the first and or second polished surface, and contacts the coated portion of the first or second components with the respective contacting surfaces to be bonded, while maintaining alignment of the two components, to form a single structure. | 12-03-2009 |
20100284430 | SYSTEMS AND METHODS FOR GENERATING HIGH REPETITION RATE ULTRA-SHORT OPTICAL PULSES - Systems, methods, circuits and/or devices for generating high repetition rate ultra-short pulses are described. As one of many examples, an optical pulse generating laser system is described that produces mode-locked optical pulses. The laser system incorporates an optical pulse generation device that includes two optical loops coupled via a beam splitter. In addition, the optical pulse generation device includes an optical gain medium that is associated with the first optical loop, and a saturable element that is disposed in either the first optical loop or the second optical loop. The saturable element is operable to modulate a group of optical pulses propagating in at least one of the first optical loop and the second optical loop to create a group of substantially regular modulated pulses. | 11-11-2010 |
20110012026 | PLANAR OPTICAL WAVEGUIDE WITH CORE OF LOW-INDEX-OF-REFRACTION INTERROGATION MEDIUM - An apparatus for illuminating a sample includes a planar waveguide. The planar waveguide includes a first substrate, including a first outer surface and a first inner surface, and a second substrate, including a second outer surface and a second inner surface. The first and second inner surfaces of the first and second substrates, respectively, are spaced apart from each other and partly define a volume for confining the sample therein. The apparatus also includes a light source for providing light directed toward the planar waveguide, such that the light is optically coupled to and contained within the planar waveguide between the outer surfaces of the first and second substrates, while illuminating at least a portion of the sample confined within the volume. | 01-20-2011 |
20110065209 | Integrated Sample Preparation and Analyte Detection - A system for sample preparation and analyte detection includes a cartridge, with a fluidic channel, a waveguide, and a capture spot. The system further includes a force field generator, an imaging system, and a fluid, which includes a sample potentially containing a target analyte, first type particles, which include binding moieties specific for the target analyte and are responsive to a force field, and second type particles, which include binding moieties specific for the target analyte and are capable of generating a signal. When the sample contains the target analyte, specific binding interactions between the target analyte and binding moieties link first and second type particles via the target analyte to form multiple-particle complex capturable at a capture spot. The force field allows manipulation of the particles and multiple-particle complex such that the detected signal from the second type particles is indicative of the target analyte within the sample. | 03-17-2011 |
20120071342 | SYSTEM AND METHOD FOR DETECTING MULTIPLE MOLECULES IN ONE ASSAY - A rapid diagnostic system that delivers a panel of serologic assay results using a small amount of blood, serum, or plasma is described. The system includes a disposable cartridge and a reader instrument, based on planar waveguide imaging technology. The cartridge incorporates a microarray of recombinant antigens and antibody controls in a fluidic channel, providing multiple parallel fluorescence assay results for a single sample. | 03-22-2012 |
20120088230 | System And Method For Cell Analysis - A system for enumeration of objects such as cells in a sample is disclosed. The system uses a low-cost cartridge and a reader instrument, based on planar waveguide imaging technology. Cells of a blood sample may be stained with fluorescence-tagged antibodies and are loaded onto the cartridge where the differentially labeled cells may be distinguished and quantified. | 04-12-2012 |
20130203627 | System and Method For Detecting Multiple Molecules in One Assay - A rapid diagnostic system that delivers a panel of serologic assay results using a small amount of blood, serum, or plasma is described. The system includes a disposable cartridge, including an integral lens portion coupled to a planar waveguide, and a reader instrument, based on planar waveguide imaging technology. The cartridge incorporates a microarray of recombinant antigens and antibody controls in a fluidic channel, providing multiple parallel fluorescence assay results for a single sample. | 08-08-2013 |