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Muyldermans

Serge Muyldermans, Hoeilaart BE

Patent application number	Description	Published
20110091446	SINGLE DOMAIN ANTIBODIES CAPABLE OF MODULATING BACE ACTIVITY - The present invention relates to single domain antibodies with a specificity for BACE1. More specifically, the invention provides single variable domain antibodies derived from camelids which bind to BACE1 and are capable of inhibiting the activity of BACE1. Said antibodies can be used for research and medical applications. Specific applications include the use of BACE1 specific antibodies for the treatment of Alzheimer's disease.	04-21-2011

Serge Muyldermans, Hoelaart BE

Patent application number	Description	Published
20100047241	FUNCTIONAL HEAVY CHAIN ANTIBODIES, FRAGMENTS THEREOF, LIBRARY THEREOF AND METHODS OF PRODUCTION THEREOF - The present invention relates to functional heavy chain antibodies, functional single domain heavy chain antibodies, functional VH domains, or functional fragments thereof comprising an amino acid which is neither a charged amino acid nor a C at position 45, and comprising an amino acid at position 103 independently chosen from the group consisting of R, G, K, S, Q, L, and P, and optionally an amino acid at position 108 independently chosen from the group consisting of Q, L and R, said positions determined according to the Kabat numbering.	02-25-2010

Xavier D. Muyldermans, Shanghai CN

Patent application number	Description	Published
20100190912	THERMOPLASTIC ELASTOMER COMPOSITION - The present invention relates to a thermoplastic elastomer composition having a durometer hardness (ASTM D2240) of Shore A 30 to 90 comprising:	07-29-2010

Xavier Daniel Dominique Jean Muyldermans, Shanghai CN

Patent application number	Description	Published
20090264590	HIGH MOLECULAR WEIGHT COUPLED BLOCK COPOLYMER COMPOSITIONS - High molecular weight coupled block copolymer composition comprising	10-22-2009