Murthi
Krishna Murthi, Andover, MA US
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20110257207 | RAF INHIBITORS - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 10-20-2011 |
20140163003 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163004 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163005 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163006 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163007 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163222 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163223 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
Krishna K. Murthi, Andover, MA US
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20080200523 | Derivatives of squaric acid with anti-proliferative activity - The present invention provides derivatives of squaric acid, in particular derivatives of 3,4-diamino-cyclobut-3-ene-1,2-dione and tautomers and isomers thereof, as a single stereoisomer or a mixture of stereoisomers, or as a pharmaceutically acceptable salt thereof. These compounds show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 08-21-2008 |
Krishna K. Murthi, Cambridge, MA US
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20090209530 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO - The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation. | 08-20-2009 |
20100004207 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto - The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation. | 01-07-2010 |
Krisna Murthi, Andover, MA US
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20110201594 | PYRIDO [2,3-D] PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 08-18-2011 |
Raghu Murthi, Bellevue, WA US
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20120326959 | REGION OF INTEREST SEGMENTATION - A sensor manager provides dynamic input fusion using thermal imaging to identify and segment a region of interest. Thermal overlay is used to focus heterogeneous sensors on regions of interest according to optimal sensor ranges and to reduce ambiguity of objects of interest. In one implementation, a thermal imaging sensor locates a region of interest that includes an object of interest within predetermined wavelengths. Based on the thermal imaging sensor input, the regions each of the plurality of sensors are focused on and the parameters each sensor employs to capture data from a region of interest are dynamically adjusted. The thermal imaging sensor input may be used during data pre-processing to dynamically eliminate or reduce unnecessary data and to dynamically focus data processing on sensor input corresponding to a region of interest. | 12-27-2012 |
20120327218 | RESOURCE CONSERVATION BASED ON A REGION OF INTEREST - A detected region of interest is used to reduce the data processed by a capture device and/or transmitted by the capture device to a console, and/or to reduce power consumption by the capture device. Raw data from the one or more sensors is processed in the capture device to reduce data corresponding to regions outside the region of interest. Such a data reduces computational requirements, which conserves power. Operational parameters of the capture device are adjusted based on the region of interest mask. A field of view, the resolution, or the sensitivity of at least one of the sensors may be narrowed to focus resources on the region of interest. Adjusting the operational parameters of a sensor reduces the power consumption of the capture device and reduces data input. An illumination source may be adjusted to focus the illumination source on the region of interest to use less power. | 12-27-2012 |
20130132095 | AUDIO PATTERN MATCHING FOR DEVICE ACTIVATION - A system and method are disclosed for activating an electric device from a standby power mode to a full power mode. The system may include one or more microphones for monitoring audio signals in the vicinity of the electric device, and a standby power activation unit including a low-power microprocessor and a non-volatile memory. Audio captured by the one or more microphones is digitized and compared by the microprocessor against predefined activation pattern(s) stored in the non-volatile memory. If a pattern match is detected between the digital audio pattern and a predefined activation pattern, the electric device is activated. | 05-23-2013 |
Shiva Murthi, Bangalore IN
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20100186017 | System and method for medical image processing - An embodiment of the present invention provides a system and method for medical image processing. The proposed system includes a grid computing framework adapted for receiving patient data including one or more patient-scan images from an end-user application, and for scheduling image processing tasks to a plurality of nodes of a grid computing network. Each of the nodes includes a central processing unit and at least one of the nodes includes programmable graphics processing unit hardware. The proposed system further includes a second framework for image processing using graphics processing unit that is operative on each node of the network. The second framework operative on any node is adapted to execute the image processing task scheduled to that node based upon the availability of graphics processing unit hardware in that node. When graphics processing unit hardware is available in the node, the second framework is adapted to execute the task on the graphics processing unit of the node using stream computation. When graphics processing unit hardware is not available in the node, the second framework is adapted to execute the task on the central processing unit of the node. | 07-22-2010 |
Vijay Murthi, Glendale, CA US
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20080243480 | System and method for determining semantically related terms - Systems and methods for determining semantically related terms are disclosed. Generally, a semantically related term tool receives a seed set and identifies a plurality of terms that constitute the seed set. For each term of the seed set, the semantically related term tool identifies concept terms associated with terms of the seed set other than the term being processed, joins the term being processed with each of the identified concept terms, and adds the resulting terms to a plurality of semantically related terms. The semantically related term tool removes invalid terms from the plurality of semantically related terms based on a language model and ranks at least a portion of the remaining terms of the plurality of semantically related terms based on a metric indicating a degree of semantical relationship between a term of the plurality of semantically related terms and one or more terms of the set seed. | 10-02-2008 |
20080243826 | System and method for determining semantically related terms - Systems and methods for determining semantically related terms are disclosed. Generally, a semantically related term tool receives a seed set and identifies a plurality of terms that constitute the seed set. For each term of the seed set, the semantically related term tool identifies one or more concept terms associated with terms of the seed set other than the term being processed, determines a plurality of concept terms based on at least one of combinations and permutations of the concept terms associated with terms of the seed set other than the term being processed, and adds the resulting terms to a plurality of semantically related terms. The semantically related term tool removes invalid terms from the plurality of semantically related terms based on a language model and ranks at least a portion of the remaining terms of the plurality of semantically related terms based on a metric indicating a degree of semantical relationship between a term of the plurality of semantically related terms and one or more terms of the set seed. | 10-02-2008 |
Vijay Murthi, Milpitas, CA US
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20090037399 | System and Method for Determining Semantically Related Terms - Systems and methods for determining semantically related terms are disclosed. Generally, a semantically related term tool trains a model to predict a degree of relevance between a candidate term and one or more seed terms. The model may be trained based on data such as a plurality of seed sets, a plurality of semantically related term sets, and a plurality of modular optimized dynamic sets (“MODS”), where each semantically related term set is related to a seed set of the plurality of seed sets and each MODS is related to a seed set of the plurality of seed sets. The semantically related term tool then determines a plurality of terms that are semantically related to one or more terms in a new seed set based on the model, the one or more terms in the seed set, and a plurality of candidate terms. | 02-05-2009 |