Mulligan, IE
Karl Mulligan, Belfast IE
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20090221437 | Transcriptome microarray technology and methods of using the same - Arrays containing a transcriptome of a diseased tissue and methods of using the arrays for diagnosis, prognosis, screening, and identification of disease are provided herein. The transcriptome arrays from diseased tissue are useful for diagnosis of a disease by analysis of the genetic profile of a tissue sample specific to a disease state. The genetic profiles are then correlated with data on the effectiveness of specific therapeutic agents. Correlating expression profiles to the effectiveness of therapeutic agents provides a way to screen and select further patients predicted to respond to those therapeutic agents, thereby minimizing needless exposure to ineffective therapy. | 09-03-2009 |
Karl Mulligan, Northern Ireland IE
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20090082218 | 3'-Based sequencing approach for microarray manufacture - Methods are described to derive design sequences for the production of nucleic acid microarrays. The present methods use high throughput 3′ sequencing of transcripts in a tissue sample or diseased state to design probes for nucleic acid microarrays. Also described are nucleic acid microarrays that possess probes directed to the extreme 3′ end of transcripts in a tissue. These microarrays preferably represent alternate polyadenylation sequences that are specific to the tissue from which the transcripts are derived. Also described are methods of using the microarrays directed to the extreme 3′ end of the transcript for evaluating gene expression in a tissue where there are reduced false positive and false negative results. | 03-26-2009 |
Niall Mulligan, County Offaly IE
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20110061337 | MASONRY SUPPORT SYSTEM AND METHOD - The invention relates to a masonry support system and method, suitable for bearing the load of a course of brick-work or defined brickwork panels, comprising a horizontal support section ( | 03-17-2011 |
Padraic Mulligan, Artane IE
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20140317078 | METHOD AND SYSTEM FOR RETRIEVING INFORMATION - The present disclosures relates to a computer implemented method and system for retrieving information. The method comprises inputting data to generate one or more records. Storing the one or more records. Classifying one or more pieces of data in the one or more records so as to associate the pieces of data to one or more concepts. Enriching the one or more records with metadata identifying concepts to which the pieces of data are associated. Inputting a search query to motivate a search of the one or more records. Classifying data of the search query by associating the data of the search query to one or more concepts. Matching the one or more concepts associated with the data of the search query with the one or more concepts associated with the one or more records. Ranking and filtering matching records based on one or more factors. Returning search hits based on the matching step. | 10-23-2014 |
Seamus Mulligan, Athlone IE
Patent application number | Description | Published |
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20100272795 | SUSTAINED RELEASE AMINOPYRIDINE COMPOSITION - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases. | 10-28-2010 |
20100272796 | SUSTAINED RELEASE AMINOPYRIDINE COMPOSITION - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases. | 10-28-2010 |
20100272807 | SUSTAINED RELEASE AMINOPYRIDINE COMPOSITION - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases. | 10-28-2010 |
20130045276 | SUSTAINED RELEASE AMINOPYRIDINE COMPOSITION - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases. | 02-21-2013 |
20140018397 | Sustained Release Aminopyridine Composition - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases. | 01-16-2014 |
Seamus Mulligan, Dublin IE
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20110172210 | METHOD FOR TITRATING CLOZAPINE - Method for titrating clozapine in treatment of psychotic disorders in a human patient in need of treatment with clozapine including administering once-a-day controlled release clozapine to the human patient titrating to a therapeutic dose of clozapine within a period of less than one week, or administering controlled release clozapine to the patient at an initial dose of at least 37.5 mg and titrating to a therapeutic dose within a period of less than ten days. | 07-14-2011 |
Thomas Mulligan, Galway IE
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20100150325 | TELEPHONE COMMUNICATION METHOD AND SYSTEM - The invention concerns telecommunications methods and systems, and more particularly methods and systems for enabling respondents, who may be potential customers, to respond to advertisements for items (goods or services) advertised by or on behalf of advertisers. Telecommunications methods and systems of the invention provide selective communication routing or forwarding to advertisers of communications made to anonymous contact identifiers selected from a pool of anonymous contact identifiers, each anonymous contact identifier able to be allocated to an item to be advertised by or on behalf of the advertiser. The anonymous contact identifier is a public telephone number or an email address, for example. The service is provided by way of hosted system for use by a plurality of advertisers. The invention has particular application in the area of classified or personal advertising in printed or online publications, such as for real estate, automotive, travel or job advertising, for sale or auction item advertising, or for dating agency advertising. | 06-17-2010 |
Thomas Mulligan, Knocknacarra IE
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20140348315 | TELEPHONE COMMUNICATION METHOD AND SYSTEM - The invention concerns telecommunications methods and systems, and more particularly methods and systems for enabling respondents, who may be potential customers, to respond to advertisements for items (goods or services) advertised by or on behalf of advertisers. Telecommunications methods and systems of the invention provide selective communication routing or forwarding to advertisers of communications made to anonymous contact identifiers selected from a pool of anonymous contact identifiers, each anonymous contact identifier able to be allocated to an item to be advertised by or on behalf of the advertiser. The anonymous contact identifier is a public telephone number or an email address, for example. The service is provided by way of hosted system for use by a plurality of advertisers. The invention has particular application in the area of classified or personal advertising in printed or online publications, such as for real estate, automotive, travel or job advertising, for sale or auction item advertising, or for dating agency advertising. | 11-27-2014 |
Tom Mulligan, Knocknacarra IE
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20090034015 | FAX CONVERSION - A fax conversion system for determining a measure of the number of pages transmitted by fax to or from a plurality of users, comprising: means for converting the transmitted pages into a format that can be output electronically rather than in hardcopy, means for counting the number of pages within an individual fax transmission, means for associating said fax transmission with a respective one of said plurality of users, and means for determining a measure of the total number of pages transmitted by fax to or from each of said plurality of users. The system may determine a measure of an equivalent number of trees saved, or the number of carbon credits gained, by not producing hardcopies of transmitted pages. | 02-05-2009 |
20130063762 | SYSTEM AND METHOD FOR MEASURING A FAX CONVERTED INTO ELECTRONIC FORMAT - A fax conversion system for determining a measure of the number of pages transmitted by fax to or from a plurality of users, comprising: means for converting the transmitted pages into a format that can be output electronically rather than in hardcopy, means for counting the number of pages within an individual fax transmission, means for associating said fax transmission with a respective one of said plurality of users, and means for determining a measure of the total number of pages transmitted by fax to or from each of said plurality of users. The system may determine a measure of an equivalent number of trees saved, or the number of carbon credits gained, by not producing hardcopies of transmitted pages. | 03-14-2013 |