Patent application number | Description | Published |
20110076230 | Novel Substituted Indoles - The present invention relates to novel amyloid binding compounds and methods for measuring effects of the compounds, by measuring changes of amyloid plaque level in living patients. More specifically, the present invention relates to a method of using the compounds of this invention as tracers in positron emission tomography (PET) imaging to study amyloid deposits in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel amyloid binding compounds as a diagnostic. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted indole derivatives, compositions, and therapeutic uses and processes for making such compounds. | 03-31-2011 |
20110081297 | Novel Substituted Pyrazoles, 1,2,4-Oxadiazoles, and 1,3,4-Oxadiazoles - The present invention relates to novel amyloid binding compounds and methods for measuring effects of the compounds, by measuring changes of amyloid plaque level in living patients. More specifically, the present invention relates to a method of using the compounds of this invention as tracers in positron emission tomography (PET) imaging to study amyloid deposits in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel amyloid binding compounds as a diagnostic. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted pyrazole derivatives, compositions, and therapeutic uses and processes for making such compounds. | 04-07-2011 |
20110085985 | NOVEL SUBSTITUTED AZABENZOXAZOLES - The present invention relates to novel amyloid binding compounds of formula (I) and methods for measuring effects of the compounds, by measuring changes of amyloid plaque level in living patients. More specifically, the present invention relates to a method of using the compounds of this invention as tracers in positron emission tomography (PET/) imaging to study amyloid deposits in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel amyloid binding compounds as a diagnostic. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted azabenzoxazole derivatives, compositions, and therapeutic uses and processes for making such compounds, or a pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof, wherein: X is O or S; A and Y independently are N, or CH; | 04-14-2011 |
Patent application number | Description | Published |
20140108381 | System and Method for Machine-to-Machine Privacy and Security Brokered Transactions - A machine-to-machine secure messaging system permits a first machine to send a message to a second machine, despite not knowing the addressing information (e.g., telephone number, IP address or other identifier) associated with the second machine. The system comprises an intermediary server with access to a database with information linking addressing information with other information related to the device, e.g., owner name, operator name and job title, etc., and facilitates a secure communication without the need for either party to the communication to know the other party's addressing information. | 04-17-2014 |
20150086068 | Instrument and Document Authentication System - A method of creating a document whose authenticity can be confirmed comprises printing a character on the document using a combination of a printing medium having a first appearance and a contaminant having a second appearance distinct from the first appearance, and wherein a first portion of the character has the first appearance but not the second appearance, and a second portion of the character has the second appearance; capturing an image containing the character; and storing the image and information relating to the document in a database. A method of authenticating a document comprises capturing an image of the document; identifying a pattern in the document, comparing the pattern to information in a database relating to an original pattern present on an originally printed document, to determine whether the pattern and the original pattern are within a specified level of similarity. | 03-26-2015 |