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Mui

Alice Mui, Burnaby CA

Patent application numberDescriptionPublished
20100311094Allosteric Modulation Of Ship Polypeptides And Uses Thereof - This invention provides a method for identifying allosteric modulators of a SHIP polypeptide, wherein said SHIP polypeptide is contacted with a test compound, and wherein said SHIP polypeptide comprises an allosteric site selected from the group consisting of a SHIP C2 domain and a SHIP PH domain.12-09-2010
20100323990SHIP 1 MODULATOR PRODRUGS - The present invention provides the use of prodrugs of pelorol and homopelorol, related compounds and pharmaceutical compositions thereof as modulators of SHIP1 activity. A compound or a pharmaceutical composition of the present invention may be used for the treatment or prophylaxis of an inflammatory, neoplastic, hematopoetic or immune disorder or condition in addition to other disorders and conditions.12-23-2010
20110171645METHODS OF DIAGNOSING ACUTE CARDIAC ALLOGRAFT REJECTION - The present invention relates to methods of diagnosing acute rejection of a cardiac allograft using genomic expression profiling, proteomic expression profiling, metabolite profiling, or alloreactive T-cell genomic expression profiling,07-14-2011
20110189680Methods of Diagnosing Rejection of a Kidney Allograft Using Genomic or Proteomic Expression Profiling - A method of determining the acute allograft rejection status of a subject, the method comprising the steps of: determining the nucleic acid expression profile of one or more than one nucleic acid markers, or one or more than one proteomic markers in a biological sample from the subject; comparing the expression profile of the one or more than one nucleic acid markers to a control profile; and determining whether the expression level of the one or more than one nucleic acid markers is increased relative to the control profile, wherein the increase of the one or more than one nucleic acid markers is indicative of the acute rejection status of the subject.08-04-2011

Alice Mui, Vancouver CA

Patent application numberDescriptionPublished
20100099737COMPOSITIONS AND METHODS FOR TREATING MYELOSUPPRESSION - The invention provides, in part, compositions and methods for protecting a hemopoietic cell, or for treating myelosuppression, in a subject in need thereof, by administering an effective amount of an inhibitor of a SH2-containing inositol-5′-phosphatase.04-22-2010

Andrew Mui, Rochester, NY US

Patent application numberDescriptionPublished
20100277253RF SIGNAL COMBINER/SPLITTER AND RELATED METHODS - A radio frequency (RF) signal combiner/splitter may include a printed circuit board (PCB) having first and second opposing major surfaces, and openings therethrough. The RF signal combiner/splitter may further include a ferromagnetic body. The ferromagnetic body may include a first portion spaced from the first major surface of the PCB, a second portion spaced from the second major surface of the PCB, and interconnecting portions coupling the first and second portions and extending through respective openings in the PCB. The PCB may include conductive traces cooperating with the ferromagnetic body to define circuitry for combining/splitting RF signals. For example, the PCB may further comprise additional conductive traces cooperating with the ferromagnetic body to define impedance matching circuitry coupled to the circuitry for combining/splitting RF signals.11-04-2010

Barbara Mui, Vancouver CA

Patent application numberDescriptionPublished
20090285878Compositions and methods for stabilizing liposomal drug formulations - The present invention is directed to liposomal compositions comprising a camptothecin, which are optimized to reduce camptothecin degradation and/or precipitation of camptothecin degradation products in the external medium. The invention further provides improved methods of formulating liposomal camptothecins, kits comprising liposome-encapsulated camptothecins, and methods of using the same to treat a variety of diseases and disorders, including cancer.11-19-2009
20110097720SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS - The invention features a method of identifying therapeutically relevant compositions which include a therapeutic agent and 2,2-Dilinoley 1-4-dimethylaminomethyl-[1,3]-dioxolane by screening for an effect of the agent on the liver of a model subject.04-28-2011
20110117125COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS - The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of specific target protein at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.05-19-2011

Patent applications by Barbara Mui, Vancouver CA

Barbara Low Shoud Mui, Vancvouer CA

Patent application numberDescriptionPublished
20110256175AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS - The present invention provides superior compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of specific target proteins at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.10-20-2011

Clifford Low Bor Mui, Burnaby CA

Patent application numberDescriptionPublished
20110104575GENERATING CLEAN SYNGAS FROM BIOMASS - Biomass is gasified to generate syngas. The syngas is subjected to thermal cracking. Heat from syngas exiting a thermal cracking stage is transferred to syngas entering the thermal cracking stage. Biomass gasification apparatus may include a thermal pathway connected to transfer heat from an outlet of a thermal cracking process to an inlet of the thermal cracking process. Energy efficiency is enhanced. Syngas may be used as fuel for engines or fuel cells, burned to yield heat, or processed into a fuel.05-05-2011

Danny Y. Mui, Birmingham, MI US

Patent application numberDescriptionPublished
20100235065METHOD FOR OPERATING A VEHICLE BRAKE SYSTEM - A method that compensates for temperature-related effects in a vehicle brake system. According to one embodiment, the method determines the temperature of a brake pad, calculates a temperature-based modifier, and then uses the temperature-based modifier to adjust one or more brake command signals provided to the vehicle brake system so that they are compensated for temperature-related changes in the coefficient of friction (μ) of the brake pad and rotor. The method may be used with brake-by-wire systems such as electrohydraulic braking (EHB) systems and electromechanical braking (EMB) systems.09-16-2010
20100280724METHODS AND SYSTEMS FOR CALIBRATING BRAKING SYSTEMS AND CONTROLLING BRAKING IN VEHICLES - A method for controlling braking in a vehicle having a brake pedal includes the steps of obtaining a first measure of braking intent based on movement of the brake pedal, obtaining a second measure of braking intent based on a force applied to the brake pedal, controlling the braking based on the first measure provided that a transition parameter is less than a first predetermined value, controlling the braking based on the second measure provided that the transition parameter is greater than a second predetermined value, and controlling the braking based on the first measure and the second measure provided that the transition parameter is greater than the first predetermined value and less than the second predetermined value.11-04-2010
20110015845METHODS AND SYSTEMS FOR CONTROLLING BRAKING OF A VEHICLE WHEN THE VEHICLE IS STATIONARY - A method for controlling braking of a vehicle includes the steps of calculating a first pressure based on a driver request, and providing pressure that does not exceed a predetermined pressure threshold if the vehicle is stationary and the first pressure is less than the predetermined pressure threshold.01-20-2011
20110049974METHODS AND SYSTEMS FOR BRAKING DIFFERENT AXLES OF A VEHICLE USING A DECELERATION VALUE - A method for controlling braking of a vehicle having a first axle and a second axle includes the steps of obtaining a deceleration value pertaining to an input from a driver of the vehicle, braking the first axle with a first pressure, braking the second axle with a second pressure that is substantially equal to the first pressure if the deceleration value has not exceeded a predetermined threshold, and braking the second axle with a third pressure that is greater than the first pressure if the deceleration value has exceeded the predetermined threshold.03-03-2011
20110130935METHODS AND SYSTEMS FOR BRAKE PEDAL TUNING AND BRAKING CONTROL IN VEHICLES - A method for calibrating a braking system of a vehicle having a brake pedal includes the steps of measuring, via a sensor, a speed of the vehicle, generating, via a processor, an optimized mapping relating a movement of the brake pedal and a deceleration of the vehicle based at least in part upon the speed of the vehicle, and calibrating, via the processor, a relationship between an engagement of the brake pedal and the deceleration of the vehicle using the optimized mapping.06-02-2011

Kathy Mui, Chelmsford, MA US

Patent application numberDescriptionPublished
20090087074METHODS AND SYSTEMS FOR PROCESSING BIOLOGICAL SPECIMENS UTILIZING MULTIPLE WAVELENGTHS - Methods, systems and computer readable media for processing one or more biological specimens carried by specimen slides. Images of objects in a specimen are acquired and objects of interest in the acquired images are identified. Additional images of identified objects of interest may be acquired at multiple wavelengths. Cellular features of objects of interest are extracted from images and may be used for classifying the specimen, e.g., as normal or suspicious/abnormal, based a probabilistic model that utilizes the extracted features.04-02-2009

Kenneth Mui, Coquitlam CA

Patent application numberDescriptionPublished
20090261073SYSTEM AND METHODS OF USING VARIABLE WAVEFORM AC ARC WELDING TO ACHIEVE SPECIFIC WELD METAL CHEMISTRIES - A system and methods for overlaying metal in an arc welding operation to achieve a resultant weld metal chemistry of the resultant weld metal. Various combinations of DC+/DC− balance settings and DC offset settings for an AC Waveform of an arc welding overlaying process may be correlated to resultant chemistries of resultant weld metals. The correlations may be subsequently used to select a combination of a balance setting and an offset setting for an AC waveform that results in a desired weld metal chemistry for an arc welding overlaying process using an overlay metal and a base substrate metal.10-22-2009

Paul Mui, Boise, ID US

Patent application numberDescriptionPublished
20110096371DUPLEX SCANNING - In one embodiment, a method for duplex scanning includes: illuminating a first side of an object with light of a first color from a group of colors; sensing the first color light reflected from the first side; illuminating a second side of the object opposite the first side with light of a second color from the group of colors simultaneously with the act of illuminating the first side with the first color light; and sensing the second color light reflected from the second side. In another embodiment, a duplex scanning method includes simultaneously illuminating each side of a document sequentially with each of multiple colors of light but in different color sequences for each side of the document so that the same color light does not illuminate both sides of the document at the same time.04-28-2011

Paul K. Mui, Boise, ID US

Patent application numberDescriptionPublished
20080247189Imaging device illumination system - An imaging device illumination system comprises first and second elongate light guides configured to emit light toward an object to be imaged, each of the first and second light guides having an input window at one end thereof for receiving light from a light source and an end face at an opposite end thereof, wherein the input window of the first light guide is disposed proximate to the end face of the second light guide.10-09-2008
20110181924IMAGE CAPTURE MODULE SUPPORT - In one embodiment, an apparatus includes a transparent platen supported over an inside of a tub, an elongated member situated in the tub in a horizontal plane, a plurality of biasing members operatively connected to the elongated member, and a plurality of gap-maintaining members operable to connect to an image capture module and operatively connected to the platen. The elongated member is movable within a tub in a vertical plane, to movably support an image capture module in a horizontal plane. The biasing members are operable to urge the elongated member towards the platen. The gap-maintaining members are operable to maintain a constant distance between platen and an image capture module.07-28-2011

Patent applications by Paul K. Mui, Boise, ID US

Raymond Mui US

Patent application numberDescriptionPublished
20110252475Complementary Character Encoding for Preventing Input Injection in Web Applications - Method to prevent the effect of web application injection attacks, such as SQL injection and cross-site scripting (XSS), which are major threats to the security of the Internet. Method using complementary character coding, a new approach to character level dynamic tainting, which allows efficient and precise taint propagation across the boundaries of server components, and also between servers and clients over HTTP. In this approach, each character has two encodings, which can be used to distinguish trusted and untrusted data. Small modifications to the lexical analyzers in components such as the application code interpreter, the database management system, and (optionally) the web browser allow them to become complement aware components, capable of using this alternative character coding scheme to enforce security policies aimed at preventing injection attacks, while continuing to function normally in other respects. This approach overcomes some weaknesses of previous dynamic tainting approaches by offering a precise protection against persistent cross-site scripting attacks, as taint information is maintained when data is passed to a database and later retrieved by the application program. The technique is effective on a group of vulnerable benchmarks and has low overhead.10-13-2011