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Moore, PA

Beverly A. Moore, Springhouse, PA US

Patent application numberDescriptionPublished
20090117104GLP-2 Mimetibodies, Polypeptides, Compositions, Methods and Uses - Mammalian GLP-2 mimetibodies, polypeptides and nucleic acids are disclosed. Methods of utilizing the mimetibodies and polypeptides to treat GLP-2 related diseases are also disclosed.05-07-2009

Charles C. Moore, Hibbs, PA US

Patent application numberDescriptionPublished
20090194346Automated Remote Carriage for Tightening Generator Wedges - A remote-controlled dynamoelectric machine maintenance vehicle that can fit and travel within the air gap between a stator and rotor of a dynamoelectric machine. The maintenance vehicle has an effectuator that can remotely attach to an adjustable wedge within a coil slot of the stator and tighten the wedge in position and then move on to repeat the process until all the wedges on the stator are secured.08-06-2009
20090301168Apparatus For Impact Testing For Electric Generator Stator Wedge Tightness - A remote-controlled dynamoelectric machine inspection vehicle that can fit and travel within a narrow air gap between a stator and rotor of a dynamoelectric machine. The inspection vehicle has an effectuator that can remotely activate a hammer driven by a high pressure pneumatic three-stage miniature piston that propels the hammer against a stator slot wedge creating an impact force that causes the wedge to vibrate. The vibrations are sensed to determine the tightness of the wedge.12-10-2009

Charles Crawford Moore, Hibbs, PA US

Patent application numberDescriptionPublished
20090126493NONDESTRUCTIVE INSPECTION HEADS FOR COMPONENTS HAVING LIMITED SURROUNDING SPACE - An inspection head where non-destructive inspection is structured to fit into narrow spaces, and to accurately and repeatably move an inspection probe along a surface to be inspected. Movement of the inspection head along an X, Y, Z, Θ, and Φ-axis is precisely controlled by individual drive mechanisms.05-21-2009

Charles S. Moore, Langhorne, PA US

Patent application numberDescriptionPublished
20080200129Method and apparatus for determining modulation levels that are supported on a channel - A logical channel is configured to match a modulation profile of an active channel. A network element is assigned to the logical channel and a ping request is sent to the network element. A response from the network element is measured, such as measuring the MER. The modulation profile is increased in the logical channel and another ping request is sent to the network element. The response is measured again, and the process is repeated until a non-linearity is detected in the response. The acceptable modulation profiles are indicated before the non-linearity is detected in the response.08-21-2008
20100157824Methods and System for Determining a Dominant Impairment of an Impaired Communication Channel - Methods are described for identifying a dominant impairment on a communication channel impaired by an interference issue. The methods include systematic examination of total power loading, systematic examination of signal power reduction, statistical examination of communication channel noise power, and systematic examination of interleaver effectiveness. Each relates to automatically diagnosing and characterizing distortion-based interference issues by monitoring the performance of a communication channel during a testing procedure. These methods enable a technician or engineer to remotely diagnose distortion-based interference issues relatively quickly without having to use external test equipment and without having to deploy technicians to various locations within the cable plant. A system by which these methods can be implemented is also disclosed.06-24-2010
20100158093Methods and System for Determining a Dominant Impairment of an Impaired Communication Channel - Methods are described for identifying a dominant impairment on a communication channel impaired by an interference issue. The methods include systematic examination of total power loading, systematic examination of signal power reduction, statistical examination of communication channel noise power, and systematic examination of interleaver effectiveness. Each relates to automatically diagnosing and characterizing distortion-based interference issues by monitoring the performance of a communication channel during a testing procedure. These methods enable a technician or engineer to remotely diagnose distortion-based interference issues relatively quickly without having to use external test equipment and without having to deploy technicians to various locations within the cable plant. A system by which these methods can be implemented is also disclosed.06-24-2010
20110069745USING EQUALIZATION COEFFICIENTS OF END DEVICES IN A CABLE TELEVISION NETWORK TO DETERMINE AND DIAGNOSE IMPAIRMENTS IN UPSTREAM CHANNELS - A system estimates impairment contributions for upstream communications in a cable television system. The system receives equalization coefficients used by end devices in the cable television system. The equalization coefficients are used by equalizers to mitigate distortion in upstream channels for the end devices. The system analyzes the coefficients based on impairment thresholds to determine whether impairment problems exist and to identify the types of impairment problems that exist.03-24-2011

Patent applications by Charles S. Moore, Langhorne, PA US

Donald E. Moore, Morrisville, PA US

Patent application numberDescriptionPublished
20100243979Animal Proof Hooded Barrier, Related Enclosure Systems and Method of Maintaining an Animal Proof Domain - The invention encompasses a substantially animal-proof barrier (“APB”) that includes (a) two supports that are laterally spaced apart to define a substantially vertical plane there between; (b) fencing material that is attached to each of the supports and spans the defined substantially vertical plane to form a simple barrier that has a top edge, a bottom edge, a front surface and a back surface, wherein the simple barrier divides a domain into a first area and a second area; and (c) a hood having an inner surface, the hood originating from the top edge of the simple barrier. An angle formed by the inner surface of the hood and the front surface of the simple barrier measures about 10 degrees to about 80 degrees, such that a channel having a substantially V-shaped cross section is formed.09-30-2010

D. Suzanne Moore, Kennett Square, PA US

Patent application numberDescriptionPublished
20100287246SYSTEM FOR PROCESSING ELECTRONIC MAIL MESSAGES WITH SPECIALLY ENCODED ADDRESSES - A method for processing an electronic mail message is disclosed comprising the steps of: accepting a request for e-mail server address information for an electronic message having an address, the address having an electronic mail receiving system domain with a recipient name encoded therein; providing an e-mail server address for the recipient name in response to the request; accepting the electronic message at the e-mail server address.11-11-2010

Patent applications by D. Suzanne Moore, Kennett Square, PA US

Gordon Moore, Wayne, PA US

Patent application numberDescriptionPublished
20080213829Materials and methods to increase peptide chain expression - DNA sequences that increase peptide chain expression when operably linked to a gene encoding the peptide chain and methods of generating a peptide chain expression host cell using the foregoing are disclosed. Peptide chain expression host cells are also disclosed.09-04-2008

Gordon Moore, Radnor, PA US

Patent application numberDescriptionPublished
20100028904WAY TO OBTAIN HIGH EXPRESSION CLONES OF MAMMALIAN CELLS USING A METHYLCELLULOSE WITH FLUORESCENT PROTEIN A OR G AND FLUORESCENT SCREENING METHOD - The invention provides a genetic screening method for identifying a transfected cell expressing the polypeptide of interest. The methods allows for high throughput screening of recombinant cells for elevated levels of expression of the polypeptide of interest using methylcellulose comprising fluorescent protein A or G to improve detection and cloning. The invention also provides capture media, formulations and methods of making and using thereof.02-04-2010

John R. Moore, Lansdale, PA US

Patent application numberDescriptionPublished
20090130317HOT AIR DRIER ASSEMBLY FOR A WATERBORNE PAINT SPRAY BOOTH - The disclosure relates to a hot air drier assembly for a solvent and waterborne paint spray booth for drying a substrate coated with liquid waterborne basecoat located inside the spray booth, comprising: a free-standing portable heat exchange device with a hot air outlet directed towards the substrate and a heat exchange fluid heating device located remotely from the paint spray booth and in fluid communication with the heat exchange device via heat exchange fluid conduits which are in fluid communication with heat exchange fluid conducting tubes for heating spray booth air directed from the spray booth air intake to the heat is exchange chamber and out the hot air outlet. The disclosure additionally relates to a paint spray booth incorporating the hot air drier assembly and methods for drying a substrate using the hot air drier assembly.05-21-2009
20100032872SOLUTION SPUN FIBER PROCESS - The invention relates to a process for forming fibers from a spinning solution utilizing a high speed rotary sprayer. The fibers can be collected into a uniform web for selective barrier end uses. Fibers with an average fiber diameter of less that 1,000 nm can be produced.02-11-2010

Jonathan T. Moore, Philadelphia, PA US

Patent application numberDescriptionPublished
20090313295System and Process for Connecting Media Content - A system for correlating a user's interests to media content, said system comprising: (a) at least one data store comprising media content data relating to people, works, and tags; (b) a relationship generator configured to generate direct relationships among said people, works and tags; (c) a connection module to generate connections between a primary person, work or tag and a first set of said people, works, and tags, wherein each person, work and tag of said first set has a direct relationship with said primary person, work or tag; and (d) a display module for causing the display of at least a portion of said first set of said people, works and tags.12-17-2009
20100299437Web Service System and Method - A system for providing a web service on a network of addressable nodes, said web service comprising a plurality of discrete, individually-addressable microservices, said system comprising: (a) at least one load balancer configured for routing a request from a node for a microservice to one of a plurality of virtual addresses, each virtual address corresponding to a unique microservice, and (b) one or more physical nodes associated with each virtual address, each physical node comprising one or more microservices, each microservice comprising a microservice-specific module for executing a particular function, said microservice-specific module linked to an interface for communicating over said network, each microservice being one of a plurality of individually-addressable microservices constituting a web service.11-25-2010
20110126296Method For Scalable Access Control Decisions - Content access may be provided and processed by assigning responsibility for obtaining entitlement data to the client's browser. Thus, in one example, the client may be configured to synchronize and coordinate data lookups associated with a content request, rather than relying on the server to do so. The network architecture may use a mediator design pattern, in which the client's browser acts as the mediator (i.e., middleman) between a content server and an entitlement data server. Accordingly, synchronous calls between server-side services might not be required. Instead, data necessary for the content server to process a client request for access to protected content may be received in the incoming request from the client's browser.05-26-2011

Patent applications by Jonathan T. Moore, Philadelphia, PA US

Keith P. Moore, North Wales, PA US

Patent application numberDescriptionPublished
20080269302Macrocyclic Tertiary Amine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease - The present invention is directed to macrocyclic tertiary amine compounds represented by general formula (I)10-30-2008
20100029701MACROCYCLIC SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - The present invention is directed to compounds of formula (I)02-04-2010

Patent applications by Keith P. Moore, North Wales, PA US

Keith P. Moore, Harleysville, PA US

Patent application numberDescriptionPublished
20100093811HIV PROTEASE INHIBITORS - Compounds of Formula I are disclosed: (I), wherein X04-15-2010
20100113415EPHA4 RTK INHIBITORS FOR TREATMENT OF NEUROLOGICAL AND NEURODEGENERATIVE DISORDERS AND CANCER - The present invention is directed to compounds of generic formula (I)05-06-2010
201100344832-AMINOIMIDAZOLE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - The present invention is directed to 2-aminoimidazole compounds of formula (I)02-10-2011

Kelly L. Moore, Dunbar, PA US

Patent application numberDescriptionPublished
20090236231ELECTRODEPOSITION OF DIELECTRIC COATINGS ON SEMICONDUCTIVE SUBSTRATES - A method includes: immersing a semiconductive substrate in an electrodeposition composition, wherein at least 20 percent by weight of resin solids in the composition is a highly cross-linked microgel component, and applying a voltage between the substrate and the composition to form a dielectric coating on the substrate. A composition for use in electrodeposition includes a resin blend, a coalescing solvent, a catalyst, water, and a highly cross-linked migrogel, wherein at least 20 percent by weight of resin solids in the composition is the highly cross-linked microgel. Another composition for use in electrodeposition includes a surfactant blend, a low ion polyol, phenoxypropanol, a catalyst, water, a flexibilizer, and a highly cross-linked migrogel, wherein at least 20 percent by weight of resin solids in the composition is the highly cross-linked microgel.09-24-2009

Matthew John Moore, Ephrata, PA US

Patent application numberDescriptionPublished
20100298772TRANCUTANEOUS DEVICES AND KITS THAT PROVIDE CUES FOR LOCATION OF INSERTION SITE, EXIT SITE AND DEVICE PATH, AND METHODS OF USE - Transcutaneous devices are disclosed that self-provide cues for exact location of transcutaneous insertion sites, exit sites, and/or the track of the device between the sites, as are methods and kits for using the transcutaenous devices to mark the sites and track of the device and for removing location cues.11-25-2010

Michael Moore, Clarks Summit, PA US

Patent application numberDescriptionPublished
20080228123BANDAGE WITH A HYDROPHILIC FOAM CONTAINING SILVER AND A HEMASTATIC AGENT - A compression stretch bandage formed from a hydrophillic foam having at least one layer of a stretchable, textile material attached to one side of the foam and a hemastasis agent attached to another side of the foam for activating the intrinsic arm of the hemostatic cascade of the healing process. The bandage may also include a silver material contained within the foam for reducing risk of infection. The bandage may be a flexible, stretchable, hydrophilic bandage that reduces the risk of infection at a wound by providing a moist environment that will aid in optimum release of silver ions into the wound.09-18-2008

Michael Charles Moore, Hibbs, PA US

Patent application numberDescriptionPublished
20090126493NONDESTRUCTIVE INSPECTION HEADS FOR COMPONENTS HAVING LIMITED SURROUNDING SPACE - An inspection head where non-destructive inspection is structured to fit into narrow spaces, and to accurately and repeatably move an inspection probe along a surface to be inspected. Movement of the inspection head along an X, Y, Z, Θ, and Φ-axis is precisely controlled by individual drive mechanisms.05-21-2009

Michael F. Moore, Dunmore, PA US

Patent application numberDescriptionPublished
20110091571METHOD OF CONTROLLING THE PROPAGATION OF MRSA, STAPH AND OTHER INFECTIONS THAT COLONIZE IN THE NOSE - A method or protocol for reducing the spread of bacterial infections such as MRSA among a population includes identifying a group of individuals at risk of carrying or becoming carriers of a bacterial infection that colonizes in the nose, determining whether any individuals can be excluded from treatment due to reasons relating to the individual's other activities or precautions taken, designating an individual or group of individuals who will receive treatment, providing a strip, the strip having an effective amount of antimicrobial agent capable of being delivered transdermally, the strip is exteriorly applied to the nose of the designated individual or group of individuals so to allow the antimicrobial agent to pass through the nose to interact with the colony to suppress the colonization, or altogether eradicate the colony.04-21-2011

Michael Lee Moore, Collegeville, PA US

Patent application numberDescriptionPublished
20090170882Methods and compositions - Compounds, compositions and methods relating to kinesin inhibition are described herein.07-02-2009
20090253908NOVEL M3 MUSCARINIC ACETYLCHOINE RECEPTOR ANTAGONISTS - Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.10-08-2009
20110136838CHEMICAL COMPOUNDS - The invention is directed to pyrido[4,3-d]pyrimidin-5(6H)-one derivatives. Specifically, the invention is directed to compounds according to Formula I:06-09-2011

M. Thomas Moore, Ephrata, PA US

Patent application numberDescriptionPublished
20110078940Single use hermetically sealing mousetrap with internal carbon dioxide killing mechanism - A single use, hermetically sealing mousetrap has a housing defining an enclosure that contains a killing mechanism which is accessible through a rotatably mounted door controlled by a spring-loaded door opening gear mechanism. Mounted to the bottom of the housing inside the enclosure is a spring-actuated setting axle and setting bar combination that is movable between a tripped position and a set position by manipulation of a setting handle positioned outside the enclosure. When the setting axle is moved to the set position, the door opening gear mechanism causes the door to open while tensioning a torsional door spring. A trip latch and bait pedal are configured to operate together to secure the setting bar in the set position, with subsequent movement of the bait pedal by a mouse serving to release the trip latch. When the trap is thereby triggered, the setting bar moves to the tripped position where it both activates the killing mechanism and releases the door opening gear mechanism. The tensioned door spring then closes the door and the killing mechanism kills the mouse. With the door closed, the enclosure is hermetically sealed with the dead mouse inside and the trap can be disposed of without any contact between the user and the carcass along with any parasites and pathogens associated therewith.04-07-2011

Patrick M. Moore, Pittsburgh, PA US

Patent application numberDescriptionPublished
20110135598METHODS TO DIAGNOSE AND IMMUNIZE AGAINST THE VIRUS CAUSING HUMAN MERKEL CELL CARCINOMA - The present invention provides isolated or substantially purified polypeptides, nucleic acids, and virus-like particles (VLPs) derived from a Merkel cell carcinoma virus (MCV), which is a newly-discovered virus. The invention further provides monoclonal antibody molecules that bind to MCV polypeptides. The invention further provides diagnostic, prophylactic, and therapeutic methods relating to the identification, prevention, and treatment of MCV-related diseases.06-09-2011

Patrick S. Moore, Pittsburgh, PA US

Patent application numberDescriptionPublished
20090068211IMMUNOGENICALLY-ENHANCED POLYPEPTIDES AND RELATED METHODS - Described herein are immunogenically-enhanced polypeptides, such as KSHV LANA1 polypeptides, related methods of eliciting an immune response to the polypeptides and related nucleotide sequences. Also described herein are novel polypeptides capable of inhibiting degradation and/or retarding synthesis of a protein when attached to or incorporated within that protein along with related methods and nucleotide sequences.03-12-2009

Peter Moore, Philadelphia, PA US

Patent application numberDescriptionPublished
20090048406PROCESS FOR PREPARING CONTINUOUSLY VARIABLE-COMPOSITION COPOLYMERS - A continuously variable composition copolymer is prepared in a reaction system, by (a) providing a reaction vessel comprising a first monomer composition; (b) providing a feed vessel comprising a second monomer composition; (c) initiating a polymerization reaction in the reaction vessel; (d) continuing the polymerization reaction during the gradual addition of the second monomer composition from the feed vessel to the reaction vessel, wherein the gradual addition of the second monomer composition is performed such that the continuously variable composition copolymer is obtained; (e) maintaining the polymerization until at least 90% of the total monomer composition has been converted to the copolymer; wherein the copolymer has a weight average molecular weight from 10,000 to 1,000,000; wherein the copolymer is soluble in lubricating oil, wherein the monomers of the first monomer composition provided in the reaction vessel comprise at least 50% by weight of all the monomers used to prepare the copolymer.02-19-2009

Richard L. Moore, Glenville, PA US

Patent application numberDescriptionPublished
20090068666Systems and Methods for Determining an Amount of Starting Reagent using the Polymerase Chain Reaction - Systems and methods for calculating an initial amount of target nucleic acid N03-12-2009
20090104605DIAGNOSIS OF SEPSIS - Methods and apparatus for predicting the development of sepsis in a subject at risk for developing sepsis are provided. Features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods and apparatus for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. A plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods and apparatus for diagnosing sepsis in a subject are provided. A plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.04-23-2009
20110105350DIAGNOSIS OF SEPSIS - Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.05-05-2011
20110118569Advanced Detection of Sepsis - The present invention relates to methods, monitors and systems measuring lysophosphatidylcholine, its derivatives and/or procalcitonin as well as at least one clinical marker (e.g. temperature or respiration rate) and/or at least one biomarker for the early detection of sepsis in a subject.05-19-2011

Patent applications by Richard L. Moore, Glenville, PA US

Robert Hunter Moore, Pittsburgh, PA US

Patent application numberDescriptionPublished
20080264184Wireless Sensors in Roll Covers - An industrial roll includes: a substantially cylindrical shell having an outer surface; a polymeric cover circumferentially overlying the shell outer surface; and a sensing system. The sensing system includes: a plurality of sensors embedded in the cover, each sensor configured to sense a data parameter; and a plurality of wireless transceivers, each transceiver connected to a respective sensor and embedded in the cover adjacent thereto. Each wireless transceiver is configured to transmit data signals from the respective sensor. Related methods and systems are also discussed.10-30-2008
20090320612Wireless Sensors in Roll Covers - An industrial roll includes: a substantially cylindrical shell having an outer surface; a polymeric cover circumferentially overlying the shell outer surface; and a sensing system. The sensing system includes: a plurality of sensors embedded in the cover, each sensor configured to sense a data parameter; and a plurality of wireless transceivers, each transceiver connected to a respective sensor and embedded in the cover adjacent thereto. Each wireless transceiver is configured to transmit data signals from the respective sensor. Related methods and systems are also discussed.12-31-2009
20100125428System and Method for Detecting and Measuring Vibration in an Industrial Roll - A system for determining the source of vibration of a nipped roll assembly includes: a first substantially cylindrical roll; a mating structure positioned relative to the first roll to form a nip therewith; a plurality of annular nip condition sensor units mounted on the first roll; each of the annular nip condition sensor units being positioned at different axial locations along the first roll and configured to provide nip condition signals from the nip, the signals indicating a nip condition at multiple circumferential locations; and a processor associated with the sensor units that receives signals from the sensor units. The processor is configured to convert the signals from the sensor units into nip condition readings for the multiple circumferential locations at each axial location. Such a system can detect irregularities in a roll or the mating structure that can cause undesired vibration.05-20-2010

Patent applications by Robert Hunter Moore, Pittsburgh, PA US

Robin D. Moore, Yardley, PA US

Patent application numberDescriptionPublished
20080262228Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof - The present invention relates to novel metabolites of 5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}quinoline, which can be useful in treating CNS disorders. The present invention further relates to processes for their preparation, to pharmaceutical compositions comprising them, and to methods of using them.10-23-2008

William J. Moore, Collegeville, PA US

Patent application numberDescriptionPublished
20100022594HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION - Compounds of Formula (I),01-28-2010
20110034513Heterocyclic Sulfonamide Inhibitors of Beta Amyloid Production - Compounds of Formula (I),02-10-2011

William Jay Moore, Collegeville, PA US

Patent application numberDescriptionPublished
20080287424AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS - The present invention provides an azolylacylquanidine compound of formula I11-20-2008
20100120725Substituted Phenylsulfonamide Inhibitors of Beta Amyloid Production - Compounds of Formula I,05-13-2010
20100267697ION CHANNEL MODULATORS - The present teachings provide compounds of Formula (I)10-21-2010

Patent applications by William Jay Moore, Collegeville, PA US