Molnár, HU
Annamaria Molnar, Budapest HU
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20120083608 | PROCESS FOR THE PREPARATION OF [4-(2-CHLORO-4- METHOXY-5-METHYLPHENYL)-5-METHYL-THIAZOLO-2-YL]-[2-CYCLOPROPYL-1-(3-FLUOR- O-4-METHYLPHENYL)-ETHYL]-AMINE - The present invention is a process for the preparation of [4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-thiazolo-2-yl]-[2-cyclopropyl-1-(3-fluoro-4-methylphenyl)-ethyl]-amine as set forth in formula (I) | 04-05-2012 |
Attila Molnar, God HU
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20130279458 | ALLOCATING IDENTIFIERS TO COMMUNICATION DEVICES - A method of allocating a routing identifier to a subscription (FIG. | 10-24-2013 |
20140155112 | SUPPORT OF SHORT MESSAGE SERVICE IN IMS WITHOUT MSISDN - The application relates to Short Message Service SMS in IMS. The relevant standard is 3GPP TR 23.863. According to current standardised procedures, a UE in an originating network can submit an encapsulated SMS to an S-CSCF which forwards it to an IP-SM-GW in the originating network. The IP-SM-GW can extract the SMS and forward it to an SMS-SC. The SMS-SC can forward the SMS to an SMS-GMSC in the terminating network which delivers it to an IP-SM-GW in the terminating network. The can use the telephone uniform resource identifier associated with the IMSI of the message received for the target UE to send the short message encapsulated in the appropriate SIP method towards an S-CSCF which forwards it to the target UE. If the target UE is available via IMS forwarding via the SMS-SC is unnecessary. Therefore, the present application proposes to deliver a SIP message (S16) with encapsulated SMS content from the IP-SM-GW (300) in the originating network directly to an IP-SM-GW (500) in the terminating network without the usage of the SMS-SC. | 06-05-2014 |
Attila Molnar, God Kalman U. 30 HU
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20110212719 | METHOD, APPARATUS AND COMPUTER PROGRAM PRODUCT FOR RELAYING CAMEL RELATED MESSAGES IN A TELECOMMUNICATIONS NETWORK - The present invention refers to a method, an apparatus and a computer program product for relaying CAMEL related messages in a telecommunication network, wherein received CAMEL related messages and corresponding subscriber data are analyzed (S | 09-01-2011 |
Balazs Molnar, Isaszeg HU
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20120252784 | 2,3,4-BENZOTHIADIAZEPINE-2,2-DIOXIDE DERIVATIVES - Novel 2,3,4-benzothiadiazepines-2,2-dioxides and processes for the preparation thereof are disclosed. The compounds influence the central nervous system and may be used to treat or prevent Alzheimer's disease, Parkinson's disease or Huntington's disease, senile dementia not of the Alzheimer's type, vascular dementia, post-stroke dementia, Korsakoff's syndrome, Down's syndrome, schizophrenia, panic disorder, post-traumatic stress disorder, anxiety or depression. | 10-04-2012 |
Béla Molnár, Budapest HU
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20100231703 | METHOD AND SYSTEM FOR DIGITIZING A SPECIMEN WITH FLUORESCENT TARGET POINTS - The present invention relates to a method and an automated fluorescent imaging system for digitizing a specimen with fluorescent target points on a microscope slide. The method uses the fluorescence microscope system for detecting and scanning said fluorescent target points. The method comprises the steps of marking the position of said specimen on said slide by visible marking means to define a specimen area containing said specimen and said fluorescent target points; capturing a bright field image of at least a portion of the slide at a first optical magnification, said portion(s) containing the specimen area and determining, from the visible marking means, a position of target fields falling within said specimen area; and scanning the target fields of the specimen area at a second optical magnification higher than said first optical magnification, said scanning including focusing on at least a part of said target fields. | 09-16-2010 |
20100290868 | SYSTEM FOR HANDLING SLIDES - The invention relates to a system for handling slides comprising a tray moving on a carriage provided with seats for the slides and with a tray moving mechanism; a slide loading arm; and a slide holding frame provided with a slide loading arm driving motor, wherein the slide holder ( | 11-18-2010 |
20130063583 | SYSTEM AND METHOD FOR DIGITIZING A MOVING SLIDE - The present invention relates to a system and a method of digitizing a moving slide ( | 03-14-2013 |
Béla Molnár, Budapest HU
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20080306964 | METHOD AND SYSTEM FOR ACCESSING A SLIDE FROM A REMOTE WORKSTATION - The invention relates to a method for accessing a slide from a plurality of digitized microscope slides from a remote workstation, wherein the plurality of digitized microscope slides are accessible via a plurality of data station units (DSU), the method comprising: | 12-11-2008 |
20090022419 | Method for realistic stitching image blocks of an electronically recorded multipart image - A method for realistic stitching and showing image blocks of an electronically recorded multipart image wherein relative positional offset values of the image blocks recorded with overlap are determined in a co-ordinate system in directions x and y and stored in matrix format, and the image blocks to be presented are stitched together on the basis of the stored values the method comprising: subdividing the overlaps of the individual image blocks into smaller regions with fixed relative positions; picking up at least one region most useful for the determination of the stitching; determining the offset goodness value based on the similarity of pattern of the image blocks; stitching the blocks of the image so that first the two image blocks characterised by the best offset goodness values are stitched together and the two image blocks characterised by the worst offset goodness values are stitched together last, whereas only the co-ordinates of the images figuring in a table are modified in the course of the stitching process; and distributing the errors produced by the stitching process over several image blocks. | 01-22-2009 |
20090046192 | AUTOMATED DIGITAL IMAGE RECORDING SYSTEM FOR AND METHOD OF DIGITIZING SLIDES - The present invention relates to an automated digital image recording system ( | 02-19-2009 |
20100231703 | METHOD AND SYSTEM FOR DIGITIZING A SPECIMEN WITH FLUORESCENT TARGET POINTS - The present invention relates to a method and an automated fluorescent imaging system for digitizing a specimen with fluorescent target points on a microscope slide. The method uses the fluorescence microscope system for detecting and scanning said fluorescent target points. The method comprises the steps of marking the position of said specimen on said slide by visible marking means to define a specimen area containing said specimen and said fluorescent target points; capturing a bright field image of at least a portion of the slide at a first optical magnification, said portion(s) containing the specimen area and determining, from the visible marking means, a position of target fields falling within said specimen area; and scanning the target fields of the specimen area at a second optical magnification higher than said first optical magnification, said scanning including focusing on at least a part of said target fields. | 09-16-2010 |
20100290868 | SYSTEM FOR HANDLING SLIDES - The invention relates to a system for handling slides comprising a tray moving on a carriage provided with seats for the slides and with a tray moving mechanism; a slide loading arm; and a slide holding frame provided with a slide loading arm driving motor, wherein the slide holder ( | 11-18-2010 |
20130063583 | SYSTEM AND METHOD FOR DIGITIZING A MOVING SLIDE - The present invention relates to a system and a method of digitizing a moving slide ( | 03-14-2013 |
Csaba Molnár, Budapest HU
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20090187032 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17alpha-ACETOXY-11beta-[4-(N,N-DIMETHYL-AMINO)-PHENYL]-19-NORPREGNA-4,9-D- IENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS - The present invention relates to a new industrial process for the synthesis of solvate-free 17α-acetoxy-11β-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB-2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process. | 07-23-2009 |
20100137622 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-- DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS - The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones. The process has the following steps: i) formation of an epoxide; ii) addition of hydrogen cyanide; iii) silylation of a hydroxyl group; iv) reaction with 4-(dimethylamino)-phenyl magnesium bromide Grignard reagent in the presence of CuCl (Teutsch reaction); v) silylation of a hydroxyl group with trimethyl chlorosilane; vi) reaction with diisobutyl aluminum hydride and after addition of acid to the reaction mixture; vii) methoxy-methylation with methoxy-methyl Grignard reagent formed in situ, while hydrolyzing the trimethylsilyl protective groups; viii) oxidation of a hydroxyl group with dicyclohexyl carbodiimide in the presence of dimethyl sulfoxide and a strong organic acid (Swern oxidation), and in given case after purification by chromatography; ix) acetylation of a hydroxyl group with acetic anhydride in the presence of perchloric acid, and in given case, purification by chromatography. The invention also relates to new intermediates of the process. | 06-03-2010 |
Csaba Molnár, Budapest HU
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20100137622 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-- DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS - The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones. The process has the following steps: i) formation of an epoxide; ii) addition of hydrogen cyanide; iii) silylation of a hydroxyl group; iv) reaction with 4-(dimethylamino)-phenyl magnesium bromide Grignard reagent in the presence of CuCl (Teutsch reaction); v) silylation of a hydroxyl group with trimethyl chlorosilane; vi) reaction with diisobutyl aluminum hydride and after addition of acid to the reaction mixture; vii) methoxy-methylation with methoxy-methyl Grignard reagent formed in situ, while hydrolyzing the trimethylsilyl protective groups; viii) oxidation of a hydroxyl group with dicyclohexyl carbodiimide in the presence of dimethyl sulfoxide and a strong organic acid (Swern oxidation), and in given case after purification by chromatography; ix) acetylation of a hydroxyl group with acetic anhydride in the presence of perchloric acid, and in given case, purification by chromatography. The invention also relates to new intermediates of the process. | 06-03-2010 |
Enikó Molnár, Érd HU
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20090215757 | Process for Preparation of High-Purity Meloxicam and Meloxicam Potassium Salt - The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam. | 08-27-2009 |
Enikó Molnár, Erd HU
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20090209617 | DULOXETINE SALTS - The subject of the present invention is the provision of new salts of duloxetine of the Formula (I) with organic acids, process for their preparation and medicinal products containing thereof. The new salts are essentially free from the impurity of the Formula (II) and possess high purity and high stability. The new duloxetine salts are prepared by reacting duloxetine free base dissolved in an organic solvent with an approximately equimolar amount of an organic acid. Particularly advantageous crystalline salts are those formed with fumaric acid, citric acid or (−)-mandelic acid. | 08-20-2009 |
20090215757 | Process for Preparation of High-Purity Meloxicam and Meloxicam Potassium Salt - The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam. | 08-27-2009 |
20090221823 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES - The present invention is related to 1-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation of 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers and salts thereof. 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers thereof are important intermediates in the preparation of non-sedating antihistamine-type active pharmaceutical ingredients. | 09-03-2009 |
20100274020 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATES - The invention relates to a process for the preparation of cyclopropyl benzyl ketone compounds of formula (II) wherein R | 10-28-2010 |
20110040093 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATE - The invention relates to a process for the preparation of compounds of general formula (III), wherein R represents fluorine or chlorine atom and X represents chlorine or bromine atom, by halogenation of cyclopropyl benzyl ketone of general formula (II), wherein R represents fluorine or chlorine atom and the halogenation is carried out in the mixture of aqueous hydrogen halide and aqueous hydrogen peroxide in the presence of a water miscible solvent or in the presence of a phase transfer catalyst; or the halogenation is carried out in the mixture of sulfuric acid and an alkali metal salt of aqueous hydrogen halide. The process can be applied preferably on industrial scale. | 02-17-2011 |
20120330018 | PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS AND INTERMEDIATE COMPOUNDS - The object of the present invention is a process for preparing the 2-acetoxy-5-(2-fluor-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]pyridine (prasugrel) of the formula (I). The process starts form crystalline 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI). Further objects of the present invention are two novel crystalline forms of 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI) and the use thereof for preparing the compound of the formula (V) and process preparing thereof. | 12-27-2012 |
20130030183 | PROCESS FOR PREPARING A PHARMACEUTICAL COMPOUND - The object of the present invention is a one-pot process for preparing the 2-acetoxy-5-(2-fluoro-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]-pyridine (prasugrel) of the formula (I) by reacting the 5,6,7,7a-tetrahydro-4H-tieno[3,2-c]-pyridine-2-on of the formula (II) with 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)-etanone of the formula (III) or with 2-chloro-1-cyclopropyl-2-(2-fluorphenyl)-etanone of the formula (IIIa) and acetylating of the formed compound of the formula (IV), wherein the reaction is carried out in the presence of an organic base with an acetylation agent without isolating the compound of the formula (IV). The coupling and acetylation are carried out in the presence of the same organic base such as triethylamine, N,N-diisopropyl-ethylamine or pyridine. At the end of the process the prasugrel of the formula (I) is purified by recrystallization from an organic solvent or a mixture of solvents. | 01-31-2013 |
20130281694 | METHOD FOR PREPARING ROSUVASTATIN SALTS - The present invention is related to methods for the preparation of pharmaceutically acceptable salts of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3R,5S,6E)-dihydroxy-hept-6-enoic acid, intermediates thereof and methods for producing said intermediates. | 10-24-2013 |
Enikó Molnár, Erd HU
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20110040093 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATE - The invention relates to a process for the preparation of compounds of general formula (III), wherein R represents fluorine or chlorine atom and X represents chlorine or bromine atom, by halogenation of cyclopropyl benzyl ketone of general formula (II), wherein R represents fluorine or chlorine atom and the halogenation is carried out in the mixture of aqueous hydrogen halide and aqueous hydrogen peroxide in the presence of a water miscible solvent or in the presence of a phase transfer catalyst; or the halogenation is carried out in the mixture of sulfuric acid and an alkali metal salt of aqueous hydrogen halide. The process can be applied preferably on industrial scale. | 02-17-2011 |
20120035162 | PROCESS FOR PREPARATION OF HIGH-PURITY MELOXICAM AND MELOXICAM POTASSIUM SALT - The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam. | 02-09-2012 |
20120330018 | PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS AND INTERMEDIATE COMPOUNDS - The object of the present invention is a process for preparing the 2-acetoxy-5-(2-fluor-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]pyridine (prasugrel) of the formula (I). The process starts form crystalline 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI). Further objects of the present invention are two novel crystalline forms of 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI) and the use thereof for preparing the compound of the formula (V) and process preparing thereof. | 12-27-2012 |
20130030183 | PROCESS FOR PREPARING A PHARMACEUTICAL COMPOUND - The object of the present invention is a one-pot process for preparing the 2-acetoxy-5-(2-fluoro-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]-pyridine (prasugrel) of the formula (I) by reacting the 5,6,7,7a-tetrahydro-4H-tieno[3,2-c]-pyridine-2-on of the formula (II) with 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)-etanone of the formula (III) or with 2-chloro-1-cyclopropyl-2-(2-fluorphenyl)-etanone of the formula (IIIa) and acetylating of the formed compound of the formula (IV), wherein the reaction is carried out in the presence of an organic base with an acetylation agent without isolating the compound of the formula (IV). The coupling and acetylation are carried out in the presence of the same organic base such as triethylamine, N,N-diisopropyl-ethylamine or pyridine. At the end of the process the prasugrel of the formula (I) is purified by recrystallization from an organic solvent or a mixture of solvents. | 01-31-2013 |
Eszter Molnar, Pecs HU
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20100022415 | ACTIVE CARRIER, ITS PRODUCTION AND ITS USE - Active carrier that consists of a carrier base ( | 01-28-2010 |
20100184762 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF - The present invention relates to compounds that are suitable for treatment of disease states and influence cellular vesicular systems, especially the formation and/or function of lipid droplets, said compound having the general formula I (I) wherein X are each independently hydrogen, halogen, —C | 07-22-2010 |
Éva Molnár, Szeged HU
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20100021927 | CHOLESTEROL LOADED INSECT CELL MEMBRANES AS TEST SYSTEMS FOR ABC TRANSPORTER PROTEINS - The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane. | 01-28-2010 |
Gàbor Molnár, Bekesszentandras HU
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20150134783 | PROVIDING DATA TO A NETWORK TERMINAL - A method and apparatus for providing data to a network terminal. A network node receives information relating to a first instance of a node concurrently runs a second instance of the client that emulates the first instance. Using the second instance, the network node generates a request for data required by the first instance. Before receiving a request for data generated by the first instance, the network node sends the request for data required by the first instance to a remote server and receives a response that includes the required data. The required data is then sent to the network terminal. The advantage of this is that the request for data required is generated before the network node receives a request from the network terminal. This allows the request to be handled more quickly. | 05-14-2015 |
Gergely Molnar, Budapest HU
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20110107550 | Vacuum Cleaner - A vacuum cleaner having a main body and a dust collecting bin, the dust collecting bin is removably mounted in a mounting portion of the main body. | 05-12-2011 |
Gergö Attila Molnar, Pecs HU
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20140128472 | TREATMENT AND PREVENTION OF DISEASES RELATED TO OXIDATIVE STRESS - The present invention relates to the field of treatment and prevention of conditions related to oxidative stress and hormone resistance. Preferably, insulin resistance, erythropoietin resistance and acetyl-choline resistance are in the focus. The invention also relates to the field of use of amino acids, in particular p-L-Tyrosine and a precursor thereof as a medicament or composition or formulation in the prevention or treatment of said conditions. | 05-08-2014 |
Gyula Molnar, Szeged HU
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20140029832 | SYSTEMS AND METHODS FOR PERFORMING SEGMENTATION AND VISUALIZATION OF IMAGES - A method for visualizing an object of interest includes obtaining an image of an object of interest, automatically separating the image into tissue clusters, automatically selecting foreground clusters from the tissue clusters, automatically generating a contour based on the selected foreground clusters, and displaying an image of the object of interest including the foreground clusters and the contour. A system and non-transitory computer readable medium are also described herein. | 01-30-2014 |
Imre Molnar, Budapest HU
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20120170297 | REFLECTOR LAMP USED AS DAYTIME RUNNING LAMP - An automotive daytime running lamp assembly includes an incandescent light source received within a reflector member. The reflector member is formed as a surface of revolution about a longitudinal axis and has an enlarged, first end, and a narrowed, second end with an opening that receives at least a portion of a light source therethrough along the longitudinal axis. A sleeve is received over a portion of the light source and at least partially extends through the reflector member opening. A cap received over the second end of the reflector member about the opening is fixedly secured to a disk, preferably by fusing or welding the components together. Likewise, the disk and metal sleeve are fixedly secured or fused/welded together so that the light source is fixed relative to the reflector member. A mounting member is provided for secure optical positioning of the assembly in a fixture of the associated automotive vehicle. | 07-05-2012 |
20130051058 | OPTICALLY ADJUSTABLE LIGHT MODULE - An optically adjustable light module, such as a daytime running lamp of a motor vehicle, includes a light source (e.g., including an LED) which is rotatable about a rotational axis and has an optical axis. An arm is connected to the light source such that movement of the arm enables rotation of the light source and adjustment of the optical axis. | 02-28-2013 |
Jozsef Molnar, Budapest HU
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20130295933 | METHODS, APPARATUSES, SYSTEM, RELATED COMPUTER PROGRAM PRODUCT FOR HANDOVER PROCEDURES - It is disclosed methods, apparatuses, system and related computer program for handover procedures. The method comprises a network node verifying if a location area of a handover destination belongs to a zone wherein a subscriber is allowed to access services and based on such verification either successfully handing over a call or rejecting a handover request. | 11-07-2013 |
20150065179 | PRE-PAGING INDICATION IN ATI AND PSI - It is provided an apparatus, comprising checking means adapted to check, upon receipt of a detection point of a service for a subscriber, if a pre-paging support is related to the service; interrogating means adapted to interrogate a location of the subscriber, wherein the interrogation comprises an indication of the pre-paging support if the result of the checking by the checking means is affirmative. | 03-05-2015 |
Laszlo Molnar, Budapest HU
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20090270371 | QUINOLINE DERIVATIVES USEFUL IN THE TREATMENT OF MGLUR5 RECEPTOR-MEDIATED DISORDERS - Compounds of formula (I): and/or enantiomers and/or racemates and/or diastereomers and/or pharmaceutically acceptable salts thereof formed with acids or bases, to the process for their preparation, to the intermediates of the preparation process, to the pharmaceutical formulations containing these compounds and to their use in the prevention and/or treatment of mGluR5 receptor-mediated disorders. | 10-29-2009 |
20140112191 | Technique for Ensuring Congruency in Link Aggregation - The present disclosure provides a technique for ensuring that a service or conversation is carried in a congruent manner on a Link Aggregation Group (LAG). The Service ID (e.g., conversation ID) to link mapping is configured on both sides of the LAG independently of each other. The Service ID to link assignment is stored in a well-defined format, e.g. in an assignment table. A digest is then prepared on the assignment table. The digest is exchanged between the two sides of the LAG. If there is a mismatch between the digests, then the service is transmitted on a predefined and agreed-upon default link if congruency has to be enforced for that particular service. Furthermore, the digest exchange allows verification on the configuration to check whether all services to be handed-off are configured on both sides. | 04-24-2014 |
20150009861 | Technique for Handling a Status Change in an Interconnect Node - A technique for status change handling in an interconnect node is described, wherein the node comprises a data plane that can assume, per service, a passive or active status. A method aspect in the node comprises transmitting, to another node, a first indication that a change has been or is about to be performed, awaiting, from the other node, reception of a second indication that the data plane in the other node has been set to the passive status, and activating, responsive to the received indication, the data plane of the node from the passive status to the active status. The method aspect in the other node further comprises receiving, from the node, the first indication, passivating, responsive to the receiving step, the data plane being in the active status to the passive status, and transmitting, upon completion of the passivating step, the second indication. | 01-08-2015 |
László Molnár, Biatorbagy HU
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20150132388 | COMPLEXES OF FULVESTRANT AND ITS DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - The present invention relates to pharmaceutically acceptable complex formulae comprising complexes of Fulvestrant, or a salt, or derivatives thereof and complexation agents and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present invention have improved physicochemical properties which makes the compound orally available and makes oral administration of the compound possible in the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. | 05-14-2015 |
Miklos Molnar, Budapest HU
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20090017440 | INCREASING THE VIABILITY AND STRESS TOLERANCE OF VIABLE BIOLOGICAL MATERIAL - The present invention relates to a method for improving viability and/or stress tolerance of viable biological material and using the said material comprising applying hydrostatic pressure to said biological material; keeping the said viable biological material at the hydrostatic pressure for a predetermined time period; releasing the hydrostatic pressure; and using the said material for any desired purpose in accordance with any useful protocol. The usage of the said biological material incorporates any techniques, protocols that are applicable in the field of assisted reproductive techniques, biotechnical and/or biotechnological manipulations. | 01-15-2009 |
20130215252 | SAMPLE IMAGING SYSTEM AND METHOD FOR TRANSMITTING AN IMAGE OF CELLS OR TISSUES LOCATED IN A CULTURING SPACE TO DATA PRCESSING MEANS - A microscope unit positioned in a culturing space for imaging cells or tissues also located therein. The microscope unit has a frame, an object holder provided on the frame and allowing the cells or tissues to be held substantially immobile during a culturing period, an imaging device arranged on the frame for the optical imaging of the cells or tissues held on the object holder and an image capturing device for capturing an image projected by the imaging device. A connection leading out of the culturing space provides electrical power to the microscope unit and is adapted to be connected to a control unit and, in turn, a processor, both located outside of the culturing space. The invention also relates to a method for monitoring cells or tissues located in the culturing space and transmitting the image thereof. | 08-22-2013 |
20140093864 | INCREASING THE VIABILITY AND STRESS TOLERANCE OF VIABLE BIOLOGICAL MATERIAL - The present invention relates to a method for improving viability and/or stress tolerance of viable biological material and using the said material comprising applying hydrostatic pressure to said biological material; keeping the said viable biological material at the hydrostatic pressure for a predetermined time period; releasing the hydrostatic pressure; and using the said material for any desired purpose in accordance with any useful protocol. The usage of the said biological material incorporates any techniques, protocols that are applicable in the field of assisted reproductive techniques, biotechnical and/or biotechnological manipulations. | 04-03-2014 |
20140329222 | INCREASING THE VIABILITY AND STRESS TOLERANCE OF VIABLE BIOLOGICAL MATERIAL - The present invention relates to a method for improving viability and/or stress tolerance of viable biological material and using the said material comprising applying hydrostatic pressure to said biological material; keeping the said viable biological material at the hydrostatic pressure for a predetermined time period; releasing the hydrostatic pressure; and using the said material for any desired purpose in accordance with any useful protocol. The usage of the said biological material incorporates any techniques, protocols that are applicable in the field of assisted reproductive techniques, biotechnical and/or biotechnological manipulations. | 11-06-2014 |
Miklós Molnár, Budapest HU
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20110189648 | POST-THAW SURVIVAL OF CRYOPRESERVED BIOLOGICAL MATERIAL BY HYDROSTATIC PRESSURE CHALLENGE - The present invention relates to a method for improving post-thaw survival of cryopreserved biological material comprising applying hydrostatic pressure to said biological material; keeping the said biological material at the hydrostatic pressure for a predetermined time period; releasing the hydrostatic pressure; and freezing the said biological material using any protocol applicable thereto. | 08-04-2011 |
20120140056 | SAMPLE IMAGING SYSTEM AND METHOD FOR TRANSMITTING AN IMAGE OF CELLS OR TISSUES LOCATED IN A CULTURING SPACE TO DATA PRCESSING MEANS - The invention relates to a sample imaging system ( | 06-07-2012 |
20130215252 | SAMPLE IMAGING SYSTEM AND METHOD FOR TRANSMITTING AN IMAGE OF CELLS OR TISSUES LOCATED IN A CULTURING SPACE TO DATA PRCESSING MEANS - A microscope unit positioned in a culturing space for imaging cells or tissues also located therein. The microscope unit has a frame, an object holder provided on the frame and allowing the cells or tissues to be held substantially immobile during a culturing period, an imaging device arranged on the frame for the optical imaging of the cells or tissues held on the object holder and an image capturing device for capturing an image projected by the imaging device. A connection leading out of the culturing space provides electrical power to the microscope unit and is adapted to be connected to a control unit and, in turn, a processor, both located outside of the culturing space. The invention also relates to a method for monitoring cells or tissues located in the culturing space and transmitting the image thereof. | 08-22-2013 |
Norbert Molnar, Budapest HU
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20080262648 | DEMAND-DRIVEN SALES MODEL CAPITALIZING ON THE POWER OF ONLINE COMMUNITY - The business method according to the present invention concerns with spatially distributed configurable vending machines and their network, especially those which produce FMCG products, like beverages, hot drinks, cocktails, soups, soaps, perfumes, etc. The configurable vending machine can produce products in different phase, proportion, appearance, look and feel, etc. regarding its configuration set up. The different configurations are generally called recipe, formula which are stored in files in Internet servers. These files can be accessed by authorized persons, who can modify, delete, create new and share with other authorized users via an Internet based online community portal. The invention describes how the configurable vending machines and its network can be managed and the communication among consumers, resellers and franchise owner. The IT back office system automatically organizes product development, market survey, marketing communication, and logistics processes and serve information about actual trends, consumption, stock status in real-time. Variety of advantages are obtained by using the method invented, like a higher integration among B2C, B2B and C2C domains (processes) yielding shorter product development cycles, lower sales and development costs, and better market knowledge. | 10-23-2008 |
Pál Molnár, Balatonalmadi HU
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20130306284 | Heat Exchanger Panel And Method For Manufacturing Thereof - The invention relates to a heat exchanger panel ( | 11-21-2013 |
Pál Molnár, Balatonalmadi HU
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20130306284 | Heat Exchanger Panel And Method For Manufacturing Thereof - The invention relates to a heat exchanger panel ( | 11-21-2013 |
Peter Molnar, Szombathely HU
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20120122728 | Method Of Screening Drugs For Reversal Of Amyloid Beta Neurotoxicity - A method of screening a compound for effectiveness in treating amyloid beta neurotoxicity comprises culturing mammalian neurons in serum-free defined medium until the neurons are electrically functional, exposing the electrically stable neurons to amyloid beta, monitoring the exposed neurons for impairment of electrical functionality, and treating the exposed neurons with the candidate drug while monitoring their electrical activity for reversal of impairment. The invention also includes a method of identifying a mammalian neuron having a biological marker conferring predisposition to development of Alzheimer's disease, the method comprising culturing the mammalian neuron in serum-free medium until the neuron is electrically functional, exposing the electrically stable neuron to amyloid beta while monitoring for impairment of electrical functionality as an indicator of presence of said biological marker, and verifying presence of the biological marker by treating the impaired neuron with an anti-amyloidogenic compound while monitoring for return of neuron functionality. | 05-17-2012 |
20130096888 | Model and Methods for Identifying Points of Action in Electrically Active Cells - The invention provides a model for generating predicted action potentials of an electrically active cell. The disclosed model includes three operatively coupled submodels. A first submodel contains Hodgkin-Huxley elements generating action potentials based on electrical equivalent circuits. A second submodel is based on reaction kinetics of cell metabolism and is operatively coupled with the first submodel. A third submodel is based on Boolean dynamics representing signaling and associated cellular processes and is operatively coupled with the first and second submodels. The invention includes storing a library of calculated action potentials and associated cellular parameters generated by the model, applying a stimulus to the electrically active cell in vitro so that the cell generates an action potential; and comparing the cell-generated action potential with those stored in the library, wherein a match is predictive of the cellular point of action of the applied stimulus according to the parameters stored. | 04-18-2013 |
Reka Melinda Molnar, Debrecen HU
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20080237135 | Pb- ion binding by polyacid- based nanoparticles - Methods are disclosed for preparing novel biodegradable nanoparticles based on complexation of poly-gamma-glutamic acid (γ-PGA) or its cross-linked derivatives with bivalent lead ions. The final products are stable in aqueous media at low pH, neutral and mild alkaline conditions. The size of the complexes depends on the pH, concentrations and the ratios of γ-PGA and lead ions | 10-02-2008 |
Sandor Molnar, Debrecen HU
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20080241948 | Mycophenolate mofetil impurity - Provided is an impurity of mycophenolate mofetil, processes for its preparation and its use as a reference. | 10-02-2008 |
20080280977 | Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid - Provided are processes for the preparation of mycophenolate mofetil and other esters of mycophenolic acid. | 11-13-2008 |
20080281111 | Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid - Provided are processes for the preparation of mycophenolate mofetil and other esters of mycophenolic acid. | 11-13-2008 |
Zsolt Molnar, Miskolc HU
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20130084608 | FUNGAL PROTEASES - The present invention provides fungal proteases and improved fungal strains that are deficient in protease production. | 04-04-2013 |