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Mizushima, Tokyo

Ayako Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20090166818Positive Photosensitive Resin Composition, and Semiconductor Device and Display Therewith - Disclosed is a positive photosensitive resin composition containing (A) an alkali-soluble resin, (B) a diazoquinone compound, (d1) an activated silicon compound and (d2) an aluminum complex. Also disclosed is a positive photosensitive resin composition containing (A) an alkali-soluble resin, (B) a diazoquinone compound, (C) a compound having two or more oxetanyl groups in one molecule and (D) a catalyst for accelerating the ring-opening reaction of the oxetanyl groups of the compound (C).07-02-2009
20100129456SUSTAINED-RELEASE NANOPARTICLE CONTAINING LOW-MOLECULAR-WEIGHT DRUG WITH NEGATIVELY CHARGED GROUP - A nanoparticle containing a low-molecular-weight drug having a negatively charged group is provided that is effectively targeted to an affected site, is capable of sufficiently sustained release of the drug, and has a reduced tendency to accumulate in the liver to cause reduced side effects. The nanoparticle containing a low-molecular-weight drug having a negatively charged group is obtained by hydrophobicizing the low-molecular-weight drug having a negatively charged group with a metal ion, and reacting the hydrophobicized drug with poly L-lactic acid or poly(L-lactic acid/glycolic acid) copolymer and poly DL- or L-lactic acid-polyethylene glycol block copolymer or poly(DL- or L-lactic acid/glycolic acid)-polyethylene glycol block copolymer.05-27-2010
20100143321THERAPEUTIC COMPOSITION FOR INTERSTITUAL PNEUMONIA - A therapeutic agent for interstitial pneumonia is provided which effectively exploits the effect of superoxide dismutase (SOD). The therapeutic composition for interstitial pneumonia contains 10 to 100 mg of lecithinized superoxide dismutase represented by the following general formula (I):06-10-2010
20100196808Positive photosensitive resin composition, cured film, protective film, insulating film, and semiconductor device and display device therewith - An objective of the present invention is to achieve both prevention of scum generation in an open area and improvement in sensitivity in patterning process of the positive photosensitive resin composition. This objective can be achieved by a positive photosensitive resin composition comprising an alkali-soluble resin (A) containing an ingredient having a molecular weight of 80,000 or more in 0.5% or less and a photosensitizing agent (B), wherein the amount of said photosensitizing agent (B) is 10 parts by weight or more and 40 parts by weight or less to 100 parts by weight of said alkali-soluble resin (A).08-05-2010

Ayoko Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20090317479NANOPARTICLES CONTAINING WATER-SOLUBLE NON-PEPTIDE LOW-MOLECULAR WEIGHT DRUG - Drug-containing nanoparticles are provided that enable effective targeting and sustained-release of a water-soluble, non-peptide, low-molecular weight drug and cause reduced accumulation of the drug in the liver. The nanoparticles containing a water-soluble, non-peptide, low-molecular weight drug are obtained by hydrophobicizing the water-soluble, non-peptide, low-molecular weight drug by a metal ion, and reacting the hydrophobicized drug with a poly(lactic acid)-polyethylene glycol block copolymer or a poly(lactic-co-glycolic acid)-polyethylene glycol block copolymer. The nanoparticles have favorable targeting and sustained-release properties and cause reduced accumulation of the drug in the liver.12-24-2009

Fuyuki Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20090097411COMMUNICATION QUALITY DIAGNOSTIC UNIT - The invention achieves a communication quality diagnostic unit capable of detecting an omen phenomenon of a communication trouble early in a stage prior to actual emergence of the communication trouble due to a noise, thereby issuing a warning. The communication quality diagnostic unit for diagnosing quality of communication for transmitting and receiving frames at predetermined interval time, comprising a frame-interval time detector for monitoring interval time between the frames, a frame-interval abnormality determiner for making determination as the case of diagnostic abnormality when a predetermined threshold value is exceeded by frame-interval time as detected, and a diagnostic abnormality notifier for notifying a host unit of the diagnostic abnormality as an alarm.04-16-2009

Hidefumi Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20080306247ANTIBODY-CONTAINING SOLUTION FORMULATIONS - An antibody-containing solution formulation comprising an organic acid and a surfactant as stabilizers; a method for suppressing the formation of visible insoluble matter and/or insoluble particles due to the presence of metal ions in an antibody-containing solution formulation, which comprises adding an organic acid to the solution; a method for suppressing the formation of visible insoluble matter and/or insoluble particles during shaking and freezing-thawing of an antibody-containing solution, which comprises adding a surfactant to the solution; and a method for stabilizing an antibody-containing solution, which comprises adding an organic acid and a surfactant.12-11-2008
20090131639ANTIBODY-CONTAINING SOLUTION FORMULATIONS - Antibody-containing solution formulations including a sugar as a stabilizer. Said solution formulations can further include a surfactant as a stabilizer.05-21-2009
20100234276ERYTHROPOIETIN SOLUTION PREPARATION - The present invention relates to an erythropoietin-containing solution preparation containing a poloxamer and having a pH of 6.5 to 7.5. The present invention also relates to a method for quantifying a protein in a trace amount, the method including the following steps: binding a protein sample to a high-intensity fluorescent dye; separating a desired analyte from the obtained sample by an appropriate separation means; and quantifying the desired analyte and converting the amount of the analyte into the amount of the protein.09-16-2010

Patent applications by Hidefumi Mizushima, Tokyo JP

Hiroshi Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20090255957Discharge Container - This discharge container is a discharge container provided with a container main body, a discharge pump and a fixing cap, in which the discharge pump is provided with a cylinder member made of a large-diameter cylinder and a small-diameter cylinder, a piston member mounted on the cylinder member and a nozzle head. The piston member is provided with a piston, a poppet valve, a piston guide, an air piston, an air piston valve and a stem. The air piston is provided with an inner tube portion engaged with the outer circumference of the piston guide, an upper wall portion having an air hole, and a sliding tube portion engaged with the large-diameter cylinder internally so as to slide freely. The stem is provided with a lower tube portion engaged with the upper part of the piston guide to form a gas-liquid mixing chamber including a ball valve internally at the upper part of the piston guide and also engaged with the upper inner tube of the inner tube portion so as to slide freely and a mesh ring mounted on the upper inner circumference of the air piston. The nozzle head is mounted on the outer circumference of the stem.10-15-2009
20090324321CONTAINER FOR VISCOUS COSMETIC - A container for a viscous cosmetic, in which upper and lower sections above and below an inner tray are air-tightly sealed off from each other to cause a viscous cosmetic received in a receiving body to be less possible to leak from the upper section to the lower section, and in which the inner tray can be smoothly moved out.12-31-2009
20100104345PROPELLING CONTAINER - A highly air-tight propelling container is provided, in which it is easy to recognize how much the content is extruded, and rotation of the rotator is prevented to avoid that the component are damaged by a wrong operation.04-29-2010
20110031276Discharge container - This discharge container is a discharge container provided with a container main body, a discharge pump and a fixing cap, in which the discharge pump is provided with a cylinder member made of a large-diameter cylinder and a small-diameter cylinder, a piston member mounted on the cylinder member and a nozzle head. The piston member is provided with a piston, a poppet valve, a piston guide, an air piston, an air piston valve and a stem. The air piston is provided with an inner tube portion engaged with the outer circumference of the piston guide, an upper wall portion, and a sliding tube portion engaged with the large-diameter cylinder internally so as to slide freely. The stem is provided with a lower tube portion engaged with the upper part of the piston guide to form a gas-liquid mixing chamber including a ball valve internally at the upper part of the piston guide and also engaged with the upper inner tube of the inner tube portion so as to slide freely and a mesh ring mounted on the upper inner circumference of the air piston. The nozzle head is mounted on the outer circumference of the stem.02-10-2011
20110062107Safety cap and container with safety cap - There is provided a safety cap which requires manual dexterity for a cover opening operation and is difficult for an infant or the like to open a cover, in which a safety function can be released, as necessary. In the safety cap configured such that a part of an outer circumferential wall of a cap main body is formed on an inward elastically deformable operating plate, a pair of engaging means and engageable with each other are provided on a peripheral wall of a cover connected to the upper portion of the cap main body via a hinge and at the upper portion of the operating plate, respectively, and the engagement is released by elastically deforming the operating plate inward so as to open the cover, the operating plate can be fixed to the cap main body or a neck portion of the container except for the operating plate by the fixing member in the inward deformed state.03-17-2011

Patent applications by Hiroshi Mizushima, Tokyo JP

Kazuki Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20120108133HEAT-RESISTANT LAMINATED CONVEYER BELT - A heat-resistant laminated conveyer belt includes a fluororesin-coated core and a reinforcement layer which is formed on the core through an adhesive layer. The core is obtained by impregnating an aramid fiber woven fabric in a fluororesin dispersion and drying and sintering the fabric. The reinforcement layer is obtained by impregnating an aramid fiber woven fabric to which stretch properties are applied in a fluororesin dispersion and drying and sintering the fabric. The aramid fiber woven fabric of the core is a woven fabric by a plain-weave seamless loom or a circular loom. The aramid fiber woven fabric of the core includes an S-twist weft yarn and a Z-twist weft yarn which are alternatively arranged.05-03-2012

Masanori Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20090115432ELASTIC BODY, ELECTROSTATIC CAPACITANCE FORCE SENSOR AND ELECTROSTATIC CAPACITANCE ACCELERATION SENSOR - The invention provides an elastic body that reduces the cost of manufacture, has high deformation stability and excellent restoration capability, and is easy to be formed, a force sensor and an acceleration sensor equipped with said elastic body.05-07-2009

Yasuo Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20090058214PLANETARY GEARED MOTOR AND DYNAMO - Provided is a DC motor capable of eliminating a DC current reverse rectification performed in a conventional DC motor and enabling rotation of maximum torque at all rotation angle and having a shape and a function for facilitating a combination with a speed change gear mechanism. Also provided is a planetary gear dynamo using the shape and the function of the present invention and capable of reducing inverse torque when the function is used as a generator.03-05-2009

Yutaka Mizushima, Tokyo JP

Patent application numberDescriptionPublished
20090317479NANOPARTICLES CONTAINING WATER-SOLUBLE NON-PEPTIDE LOW-MOLECULAR WEIGHT DRUG - Drug-containing nanoparticles are provided that enable effective targeting and sustained-release of a water-soluble, non-peptide, low-molecular weight drug and cause reduced accumulation of the drug in the liver. The nanoparticles containing a water-soluble, non-peptide, low-molecular weight drug are obtained by hydrophobicizing the water-soluble, non-peptide, low-molecular weight drug by a metal ion, and reacting the hydrophobicized drug with a poly(lactic acid)-polyethylene glycol block copolymer or a poly(lactic-co-glycolic acid)-polyethylene glycol block copolymer. The nanoparticles have favorable targeting and sustained-release properties and cause reduced accumulation of the drug in the liver.12-24-2009
20100129456SUSTAINED-RELEASE NANOPARTICLE CONTAINING LOW-MOLECULAR-WEIGHT DRUG WITH NEGATIVELY CHARGED GROUP - A nanoparticle containing a low-molecular-weight drug having a negatively charged group is provided that is effectively targeted to an affected site, is capable of sufficiently sustained release of the drug, and has a reduced tendency to accumulate in the liver to cause reduced side effects. The nanoparticle containing a low-molecular-weight drug having a negatively charged group is obtained by hydrophobicizing the low-molecular-weight drug having a negatively charged group with a metal ion, and reacting the hydrophobicized drug with poly L-lactic acid or poly(L-lactic acid/glycolic acid) copolymer and poly DL- or L-lactic acid-polyethylene glycol block copolymer or poly(DL- or L-lactic acid/glycolic acid)-polyethylene glycol block copolymer.05-27-2010
20100143321THERAPEUTIC COMPOSITION FOR INTERSTITUAL PNEUMONIA - A therapeutic agent for interstitial pneumonia is provided which effectively exploits the effect of superoxide dismutase (SOD). The therapeutic composition for interstitial pneumonia contains 10 to 100 mg of lecithinized superoxide dismutase represented by the following general formula (I):06-10-2010
20100322902DRUG-CONTAINING SUSTAINED RELEASE MICROPARTICLE, PROCESS FOR PRODUCING THE SAME AND PREPARATION CONTAINING THE MICROPARTICLE - Sustained release microparticles suitable for various types of drugs, or drug-containing sustained release microparticles capable of sustained release of drugs over a period of three days or more and capable of inhibiting initial burst release; a process for producing the same; and preparations containing the microparticles are disclosed. The drug-containing sustained release microparticles comprise a drug other than human growth hormone and a porous apatite derivative, and optionally include a water-soluble bivalent metal compound. The drug-containing sustained release microparticles can be produced by dispersing under agitation microparticles of a porous apatite derivative in an aqueous solution containing a drug so that the aqueous solution infiltrates into the porous apatite derivative; optionally adding an aqueous solution containing a water-soluble bivalent metal compound that may infiltrate into the porous apatite derivative; further adding additives such as a stabilizer to the mixture; and effecting lyophilization or vacuum drying.12-23-2010

Patent applications by Yutaka Mizushima, Tokyo JP