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Mizusawa, Tokyo
Hidehiro Mizusawa, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20100234282 | SYSTEM FOR DELIVERING NUCLEIC ACIDS FOR SUPPRESSING TARGET GENE EXPRESSION BY UTILIZING ENDOGENOUS CHYLOMICRON - The object of present invention is to provide a system that can deliver in vivo nucleic acids such as an siRNA for suppressing a target gene expression in vivo more safely and efficiently, and to provide an expression-suppressing agent and a pharmaceutical composition utilizing the system. An introduction substance into chylomiclon, particularly nucleic acids to which an alpha-tocopherol is bound for suppressing a target gene expression, can be delivered more safely and efficiently into hepatic cells in vivo by administering the nucleic aids under the condition where the production of chylomicron is induced in the body. Alternatively, alpha-tocopherol-bound nucleic acids are mixed with extracted chylomiclon, and then they are administered. Consequently, a target gene expression is suppressed, thereby a disease caused by an elevated expression of the target gene can be treated more safely and efficiently. | 09-16-2010 |
Hiroshi Mizusawa, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20110064452 | Image forming apparatus, image forming method, and process cartridge - An image forming apparatus including multiple image bearing members that bear respective electrostatic latent images, provided in tandem; multiple developing devices that develop the respective electrostatic latent images with toner to form respective toner images; an intermediate transfer member onto which the multiple toner images are transferred to form a composite toner image; multiple first lubricant applicators that apply a lubricant to the respective image bearing members; and a second lubricant applicator that applies a lubricant to the intermediate transfer member, provided upstream from the extreme upstream image bearing member. In this image forming apparatus, the amount of lubricant applied from the extreme upstream first lubricant applicator to the extreme upstream image bearing member is smaller than that applied from each of the other lubricant applicators to the respective image bearing members. | 03-17-2011 |
Ken-Ichi Mizusawa, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20080206680 | Composition for forming anti-reflective coating for use in lithography - There is provided a composition for forming anti-reflective coating for anti-reflective coating that has a good absorption of light at a wavelength utilized for manufacturing a semiconductor device, that exerts a high protection effect against light reflection, that has a high dry etching rate compared with the photoresist layer. Concretely, the composition for forming anti-reflective coating contains a triazine trione compound, oligomer compound or polymer compound having hydroxyalkyl structure as substituent on nitrogen atom. | 08-28-2008 |
Masayuki Mizusawa, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20080212173 | Illumination Optical Apparatus and Optical Apparatus - There are provided an illumination optical apparatus and an optical apparatus using this illumination optical apparatus that are capable of efficiently collecting light emitted from a light-emitting section for illumination with less illumination nonuniformity, without having to employ a complicated structure. There are provided a light-emitting sections; a lens system for converting a diverging beam emitted from the light-emitting section into a beam of collimated light; an afocal optical system for adjusting the cross-sectional area of a beam of collimated light obtained by the lens array; a fly-eye lens for forming a plurality of light-source images from the collimated light whose cross-sectional area is adjusted by the afocal optical system; and a Koehler illumination optical system that uses the plurality of light-source images formed by the fly-eye lens as a light source. | 09-04-2008 |
| 20080252965 | EPI-ILLUMINATION OPTICAL SYSTEM FOR MICROSCOPES - The invention relates to an epi-illumination optical system for microscopes which relies upon a Köhler illumination system using a collective lens array, having simplified adjustment function capable of adjusting the image position of a light source to the back focal position of each microscope objective lens in operable association with microscope objective lens replacement. The invention provides an epi-illumination optical system for microscopes, with an objective lens serving as a condenser lens, which comprises a light source, a collimate lens, and a lens array. The epi-illumination optical system further comprises a projection optical system adapted to project an image of light source formed by collective lens array. The projection optical system comprises a partial optical system movable in an optical axis direction, so that the imaging position for the image array of light source is adjustable to the back focal position of the objective lens | 10-16-2008 |
Naomi Mizusawa, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20080227165 | Process for producing conjugated fatty acid and food/drink produced by the process - A conjugated fatty acid such as the cis-9, trans-11 isomer of conjugated linoleic acid having high bioactivities is selectively and efficiently produced by conjugating an unsaturated fatty acid having at least two double bonds with the use of viral cells, dead cells or a cell extract of at least one bacterium selected from the group consisting of | 09-18-2008 |
Susumu Mizusawa, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20080292751 | Lactic Acid Bacteria Fermented Substance and Fermented Milk Food Product Containing the Same - An object of the invention is to provide a lactic acid bacteria fermentation product, which has been obtained by culturing lactic acid bacteria on a medium containing an extract of at least one food material selected from the group consisting of rice bran, persimmon leaves, | 11-27-2008 |
| 20090252709 | NOVEL BACTERIUM BELONGING TO THE GENUS BIFIDOBACTERIUM AND UTILIZATION OF THE SAME - It is intended to provide | 10-08-2009 |
| 20100015281 | FERMENTED FOOD CONTAINING BIFIDOBACTERIUM BACTERIA AND METHOD FOR PRODUCING THE SAME - Provided is a fermented food containing an extract of at least one plant material selected from the group consisting of turmeric, | 01-21-2010 |