Patent application number | Description | Published |
20150112214 | BLOOD PRESSURE MEASURING DEVICE AND BLOOD PRESSURE MEASURING METHOD - A blood pressure measuring device includes: a blood vessel diameter measurement unit which measures a blood vessel diameter of a measurement target blood vessel of a subject; a pressurizing-type sphygmomanometer which acquires a blood pressure of the subject; a calculation unit which calculates a correlation between the blood vessel diameter and the blood pressure on the basis of a result of the measurement by the blood vessel diameter measurement unit and a result of the measurement by the pressurizing-type sphygmomanometer at plural timings during artificial dialysis on the subject with different blood pressure values; and a blood pressure calculation unit which calculates a blood pressure on the basis of the blood vessel diameter of the blood vessel measured by the blood vessel diameter measurement unit, using the correlation, after the artificial dialysis. | 04-23-2015 |
20150238169 | ULTRASONIC MEASUREMENT APPARATUS AND ULTRASONIC MEASUREMENT METHOD - In an ultrasonic measurement apparatus, an ultrasonic sensor transmits an ultrasonic wave toward a blood vessel and receives a reflected wave. Then, in a processing unit of a main device, an ultrasonic measurement control section, a respiratory fluctuation component separation section, and a respiratory rate calculation section analyze the displacement of a vascular wall in a depth direction from the body surface using a received signal of the reflected wave, and detect the number of breaths per unit time using the analysis result. The unit time may be one minute or one second, for example. | 08-27-2015 |
20150289835 | ULTRASONIC BLOOD PRESSURE MEASURING DEVICE AND ULTRASONIC BLOOD PRESSURE MEASURING METHOD - An ultrasonic blood pressure measuring device receives a reflected wave of an ultrasonic wave transmitted to a blood vessel, and measures the degree of displacement of a blood vessel wall of the blood vessel based on the reflected wave of the ultrasonic wave during at least one heartbeat period. Then, cardiac systolic blood pressure and cardiac diastolic blood pressure are calculated from a maximum value of the blood vessel diameter, which appears after the peak of the degree of displacement of the blood vessel wall, and a minimum value of the blood vessel diameter, which appears before the peak, using a correlation between the diameter of blood vessel and blood pressure set in advance. | 10-15-2015 |
20150289836 | ULTRASONIC BLOOD PRESSURE MEASURING DEVICE AND ULTRASONIC BLOOD PRESSURE MEASURING METHOD - An ultrasonic blood pressure measuring device receives a reflected wave of an ultrasonic wave transmitted to a blood vessel, and measures the diameter of the blood vessel based on the reflected wave of the ultrasonic wave during at least one heartbeat period. Then, the ultrasonic blood pressure measuring device calculates cardiac systolic blood pressure and cardiac diastolic blood pressure from the maximum value of the blood vessel diameter, which appears after the peak of the degree of change in the measured blood vessel diameter, and the minimum value of the blood vessel diameter, which appears before the peak, using a correlation between the diameter of the blood vessel and blood pressure set in advance. | 10-15-2015 |
Patent application number | Description | Published |
20090169866 | NANOCOMPOSITE MATERIALS WITH DYNAMICALLY ADJUSTING REFRACTIVE INDEX AND METHODS OF MAKING THE SAME - A concept and synthesis technology for a composite nanoparticle material which can be used to develop nanocomposite films and suspension with 1) dynamic refractive index control across a wide temperature and wavelength of light, and specified refractive index range, or 2) magnetic susceptibility or electronic conductivity over a wide temperature, magnetic field and electric field range. Core-shell nanoparticles can be made from two or more materials whose temperature dependent, electric field dependent or magnetic field dependent properties compensate one another will dynamically maintain a targeted refractive index, electronic conductivity or magnetic susceptibility over a specified temperature, electric and/or magnetic field range. Mixtures of composite nanoparticles with complementary behavior can optionally be used to widen the operational range of the nanocomposite material further or dampen temperature dependency in a controlled manner, e.g. using a non-random distribution of particles to affect a compensating gradient in the property of interest. | 07-02-2009 |
20100285611 | PHOTOBLEACHING RESISTANT PH SENSITIVE DYE NANOREACTORS WITH DUAL WAVELENGTH EMISSION - A pH sensitive nanoreactor can include an aqueous core within a liposome. The aqueous core can include a pH responsive dye dispersed or dissolved within the core. The liposome provides a nanoscale environment for the dye. Further, a nanoshell can be present which encapsulates the liposome. The nanoshell can be permeable to hydrogen ions while also protecting the dye from exposure to deleterious compounds and photobleaching. | 11-11-2010 |
20120077662 | Method And Apparatus For Continuous Removal Of Submicron Sized Particles In A Closed Loop Liquid Flow System - A method and apparatus for continuous removal of submicron sized artificial oxygen carriers (rAOC) and other materials such as cancer cells and bacteria from blood and other liquids. A centrifuge rotor having a curved shape is offset on a spinning rotor base and creates contiguous areas of low to high centrifugal force depending on the distances from the axis of the rotor base. This creates a density gradient field that separates materials of different densities input to the centrifuge that exit via different outputs. A monitor detects any red blood cells (RBC) with the rAOC before they exit the centrifuge. If there are any RBC detected logic circuitry changes the speed of rotation of the rotor, and the flow rate of pumps inputting and removing separated blood and rAOC to and from the centrifuge until there are no RBC in the rAOC exiting the centrifuge. | 03-29-2012 |
20120164231 | Synthesis Of Oxygen Carrying, Turbulence Resistant, High Density Submicron Particulates - An artificial oxygen carrier (AOC) for use in the body. A first gas permeable first shell encloses an oxygen carrying agent. The first shell has a second oxygen carrying agent surrounding it, and there is a second gas permeable shell enclosing the second agent. The concentric shells are not subject to turbulent breakup, or chemical decomposition, do not release the agents. | 06-28-2012 |
20140008301 | THERAPEUTIC RETRIEVAL OF TARGETS IN BIOLOGICAL FLUIDS - Method and apparatus for removing high density particles from a biological fluid such as blood using aphaeresis. The particles are preferably sub-micron in size and denser than normally occurring components of the fluid and can be removed by a modified reverse-flow gradient density centrifuge without damaging the fluid. The particles can be provided to a patient in vivo or added to the fluid after it is removed from the patient. Some particles can carry and deliver oxygen and scavenge carbon dioxide. Other particles are conjugated to capture molecules for attaching to targets such as cancer cells, viruses, pathogens, toxins, or excess concentrations of a drug or element in the fluid. The targets are then removed from the fluid along with the particles by the aphaeresis instrument. | 01-09-2014 |
20150238432 | Synthesis Of Oxygen Carrying, Turbulence Resistant, High Density Submicron Particulates - An artificial oxygen carrier (AOC) for use as a blood substitute in the body. A first gas permeable shell encloses an oxygen carrying agent. The first gas-permeable shell has a second oxygen carrying agent surrounding it, and there is a second gas-permeable shell enclosing the second agent. The concentric shells are not subject to turbulent breakup, or chemical decomposition, and do not release the oxygen carrying agents into the blood. | 08-27-2015 |
20150321204 | Method And Apparatus For Continuous Removal Of Sub-Micron Sized Particles In A Closed Loop Liquid Flow System - A method and apparatus for continuous removal of sub-micron sized particles and other materials attached thereto such as cancer cells and bacteria from blood and other liquids. A centrifuge rotor having a curved shape is offset on a spinning rotor base and creates contiguous areas of low to high centrifugal force depending on the distances from the axis of the rotor base. This creates a density gradient field that separates materials of different densities input to the centrifuge that exit via different outputs. A monitor detects components of the fluid that are mixed with the particles before they exit the centrifuge. If there are any unwanted components detected with the particles logic circuitry changes the speed of rotation of the rotor, and the flow rate of pumps inputting and removing separated fluid and particles to and from the centrifuge until there are no unwanted components in the fluid exiting with the particles from the centrifuge. | 11-12-2015 |
20160038668 | Therapeutic Retrieval of Targets in Biological Fluids - Method and apparatus for removing high density particles from a biological fluid such as blood using aphaeresis. The particles are preferably sub-micron in size and denser than normally occurring components of the fluid and can be removed by a modified reverse-flow gradient density centrifuge without damaging the fluid. The particles can be provided to a patient in vivo or added to the fluid after it is removed from the patient. Some particles can carry and deliver oxygen and scavenge carbon dioxide. Other particles are conjugated to capture molecules for attaching to targets such as cancer cells, viruses, pathogens, toxins, or excess concentrations of a drug or element in the fluid. The targets are then removed from the fluid along with the particles by the aphaeresis instrument. | 02-11-2016 |