Miyazaki, US
Douglas Miyazaki, Winston-Salem, NC US
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20110269109 | PELVIC SURGERY TRAINING MODEL - A male or female human pelvic model for teaching, practicing, or evaluating proficiency in physical examination, medical or surgical techniques, or procedures involving the pelvis are disclosed. The pelvic model can include replaceable pelvic skeletal frame and normal, pathological, or other modules providing 3D anatomical representations of various body components, such as skin, organs, muscles, vessels, connective tissues, ligaments, tendons, or nerves. The pelvic model can include portions that can retain pressurized fluid, such as to mimic a body organ, cavity, or vessel that retains fluid, so that leakage can occur, such as upon unintended cutting or puncture. A rotating open-top pelvic region structure can permit viewing or video capture during the simulated procedure. | 11-03-2011 |
Douglas Wayne Miyazaki, Winston-Salem, NC US
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20110091855 | PELVIC SURGERY TRAINING MODEL - A male or female human pelvic model for teaching, practicing, or evaluating proficiency in physical examination, medical or surgical techniques, or procedures involving the pelvis are disclosed. The pelvic model can include replaceable pelvic skeletal frame and normal, pathological, or other modules providing 3D anatomical representations of various body components, such as skin, organs, muscles, vessels, connective tissues, ligaments, tendons, or nerves. The pelvic model can include portions that can retain pressurized fluid, such as to mimic a body organ, cavity, or vessel that retains fluid, so that leakage can occur, such as upon unintended cutting or puncture. A rotating open-top pelvic region structure can permit viewing or video capture during the simulated procedure. | 04-21-2011 |
Erika Miyazaki US
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20150230412 | WALL-SURFACE FLOWER BED STRUCTURE AND METHOD FOR FORMING WALL-SURFACE FLOWER BED - The present invention is a wall-surface flower bed structure, wherein work efficiency is better, root damage when plants are transferred is prevented, and the designability of the wall-surface flower bed is improving. This wall-surface flower bed structure ( | 08-20-2015 |
Makoto Miyazaki, Madison, WI US
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20090221677 | Methods for Reducing Body Fat and Increasing Lean Body Mass by Reducing Stearoyl-COA Desaturase 1 Activity - It is disclosed here that inhibiting the activity of the enzyme stearoyl-CoA desaturase (SCD1) in an animal causes the animal to have less body fat and greater lean body mass. The lower of SCD1 activity level can be accomplished by inhibiting activity of the enzyme or lowering levels of active enzyme in the subject. | 09-03-2009 |
20090260094 | Stearoyl-CoA Desaturase 4 Gene - The cloning of a fourth mouse SCD gene, mSCD4, as well as its corresponding cDNA and amino acid sequences are disclosed. Mouse SCD4 is expressed mainly in the heart tissue and synthesizes the bulk of monounsaturated fatty acids in the heart. The disclosure here enables new tools (e.g., nucleic acids, polypeptides, antibodies, vectors, recombinant cells, and transgenic and knock-out animals) for studying the function of various SCD isoforms and their connection to various disease conditions. New tools for converting saturated fatty acyl-CoA to monounsaturated acyl-CoA and for identifying SCD modulators including isoform-specific modulators are also enabled. In addition, given that accumulation of lipid in the heart (fatty heart) can have deleterious consequences, the present invention also provides a new prevention and treatment target for fatty heart as well as methods for screening candidate drugs. | 10-15-2009 |
20110060014 | Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents - The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids, wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases. | 03-10-2011 |
20110287084 | METHOD FOR REDUCING BODY FAT AND INCREASING LEAN BODY MASS BY REDUCING STEAROYL-COA DESATURASE 1 ACTIVITY - It is disclosed here that inhibiting the activity of the enzyme stearoyl-CoA desaturase (SCD1) in an animal causes the animal to have less body fat and greater lean body mass. The lower of SCD1 activity level can be accomplished by inhibiting activity of the enzyme or lowering levels of active enzyme in the subject. | 11-24-2011 |
20120164154 | METHOD FOR INCREASING INSULIN SENSITIVITY AND FOR TREATING AND PREVENTING TYPE 2 DIABETES - It is disclosed here that insulin sensitivity in a human or non-human animal can be increased by reducing stearoyl-CoA desaturase-1 (SCD1) activity in the animal. This provides a new tool for treating and preventing type 2 diabetes. Also disclosed are methods for identifying agents that can increase insulin sensitivity in a human or non-human animal through determining the agents' effects on SCD1 activity. | 06-28-2012 |
Masamitsu Miyazaki, Novi, MI US
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20120322423 | Hands-Free Device for Mobile-Phone Handset and Phone Book Registration Method - A hands-free device for a mobile-phone handset includes: a read unit that detects connection of a mobile-phone handset and reads identifying information of the mobile-phone handset connected; a phone book creation unit that creates a phone book for each piece of the identifying information; and a change unit that changes the identifying information assigned to the phone book to identifying information of another mobile-phone handset. | 12-20-2012 |
Tetsuro Miyazaki, Brookline, MA US
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20130064832 | NOTCH INHIBITION IN THE TREATMENT AND PREVENTION OF A METABOLIC DISEASE OR DISORDER AND CARDIOVASCULAR COMPLICATIONS THEREOF - The present invention is directed to methods of treating or preventing a metabolic disease or disorder and cardiovascular complications and other complications thereof by administering agents that inhibit the NOTCH signaling pathway. In addition, the invention encompasses methods for determining whether a patient is at increased risk for developing these conditions by determining the amount, function, or activity of NOTCH pathway components in biological samples derived from the patient or in imaging analyses. | 03-14-2013 |