Mir, CA
Alain Mir, Redwood City, CA US
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20150038336 | METHOD FOR RELATIVE QUANTIFICATION OF NUCLEIC ACID SEQUENCE, EXPRESSION, OR COPY CHANGES, USING COMBINED NUCLEASE, LIGATION, AND POLYMERASE REACTIONS - The present invention is directed to methods for identifying the presence of one or more target nucleotide sequences in a sample that involve a nuclease-ligation reaction. In some embodiments, the ligation products formed in the nuclease-ligation process of the present invention are subsequently amplified using a polymerase chain reaction. The ligated product sequences or extension products thereof are detected, and the presence of one or more target nucleotide sequences in the sample is identified based on the detection. | 02-05-2015 |
Alain Mir, Fremont, CA US
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20150362420 | SYSTEMS FOR SINGLE OR MULTIPLE CELL COUNTING AND DISPENSING - The present invention provides methods, device, assemblies, and systems for counting and dispensing single or multiple cells (e.g., into the open wells of a multi-well testing device). In certain embodiments, the systems comprise: a) a fluid movement component composed of upstream and downstream electrode conduits connected to a non-conductive conduit, and b) an electronic signal detector electrically linked to the upstream and downstream electrode conduits such that, when a fluid is present in the fluid movement component, an electrical circuit is established that is altered when a cell passes through the non-conductive conduit. In other embodiments, the systems comprises a) a fluid movement component composed of an upstream electrode conduit connected to a non-conductive conduit, b) an in-well electrode, and c) an electronic signal detector electrically linked to the upstream electrode conduit and the in-well electrode. | 12-17-2015 |
Alain Mir, Cupertino, CA US
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20100120038 | ASSAY METHODS FOR INCREASED THROUGHPUT OF SAMPLES AND/OR TARGETS - The present invention provides assay methods that increase the number of samples and/or target nucleic acids that can be analyzed in a single assay. | 05-13-2010 |
20100178655 | SINGLE-CELL NUCLEIC ACID ANALYSIS - The present invention provides methods for analysis of genomic DNA and/or RNA from small samples or even single cells. Methods for analyzing genomic DNA can entail whole genome amplification (WGA), followed by preamplification and amplification of selected target nucleic acids. Methods for analyzing RNA can entail reverse transcription of the desired RNA, followed by preamplification and amplification of selected target nucleic acids. | 07-15-2010 |
20100203538 | DETERMINATION OF COPY NUMBER DIFFERENCES BY AMPLIFICATION - The present invention provides for determining relative copy number difference for one or more target nucleic acid sequences between a test sample and a reference sample or reference value derived therefrom. The methods facilitate the detection of copy number differences less than 1.5-fold. | 08-12-2010 |
20140154679 | DETERMINATION OF COPY NUMBER DIFFERENCES BY AMPLIFICATION - The present invention provides for determining relative copy number difference for one or more target nucleic acid sequences between a test sample and a reference sample or reference value derived therefrom. The methods facilitate the detection of copy number differences less than 1.5-fold. | 06-05-2014 |
20140186827 | ASSAYS FOR THE DETECTION OF GENOTYPE, MUTATIONS, AND/OR ANEUPLOIDY - The present invention provides amplification-based methods for detection of genotype, mutations, and/or aneuploidy. These methods have broad applicability, but are particularly well-suited to detecting and quantifying target nucleic acids in free fetal DNA present in a maternal bodily fluid sample. | 07-03-2014 |
20140193812 | SINGLE-CELL NUCLEIC ACID ANALYSIS - The present invention provides methods for analysis of genomic DNA and/or RNA from small samples or even single cells. Methods for analyzing genomic DNA can entail whole genome amplification (WGA), followed by preamplification and amplification of selected target nucleic acids. Methods for analyzing RNA can entail reverse transcription of the desired RNA, followed by preamplification and amplification of selected target nucleic acids. | 07-10-2014 |
20140296090 | ASSAY METHODS FOR INCREASED THROUGHPUT OF SAMPLES AND/OR TARGETS - The present invention provides assay methods that increase the number of samples and/or target nucleic acids that can be analyzed in a single assay. | 10-02-2014 |
Ari Mir, Los Angeles, CA US
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20120303449 | SYSTEMS AND METHODS FOR ELECTRONICALLY MANAGING CONTENT - Systems and methods are provided for electronically managing content. In one embodiment, information identifying content items found on a page is received from a client system through code embedded on the page. Systems and methods for associating advertisement data with content items are also disclosed. | 11-29-2012 |
Ari Mir, San Francisco, CA US
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20130225266 | PROVIDING TOKEN-BASED ACCESS TO APPLICATION FEATURES - Systems and methods are provided for implementing token-based access to application features of an application executable by a computing device. In some embodiments, a number of initial electronic credits, or tokens, may be assigned to a user of an application, where a token enables the user to access one or more features of the application. The number of tokens to be assigned to the user may be determined based at least in part on data regarding users that were previously assigned tokens of varying amounts. When a user selection is received corresponding to a request to access certain features of the application, one or more tokens may automatically be subtracted from the number of tokens available to the user. In some embodiments, additional tokens may be purchased or otherwise obtained by the user. | 08-29-2013 |
Ashfaq Mir, Fountain Valley, CA US
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20090056123 | Friction lock design for adjustable pump head to allow for 360.degree. rotation - A method and apparatus are provided for coupling a pump head ( | 03-05-2009 |
Ashfaq M. Mir, Fountain Valley, CA US
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20080230124 | Method for replacing seals in recreational vehicles gate valves without removing valve housing from plumbing - The present invention provides a method for replacing seals in recreational vehicles gate valves without removing valve housing from plumbing. The method for replacing blade seals in a gate valve features coupling a valve housing of the gate valve to suitable plumbing, the valve housing having a removable blade seal cartridge slidably arranged and latched therein in order to receive a movable blade of a drive unit of the valve gate to control the flow of the medium through the valve gate and to prevent the medium from entering the drive unit; and unlatching the removable blade seal cartridge from the valve housing so as to enable replacement of the blade seal cartridge without having to remove the valve housing from the suitable plumbing. | 09-25-2008 |
20080230125 | Compartmentalized electric/manual gate valve - The present invention provides a gate valve for controlling the flow of a medium through suitable plumbing, featuring a valve housing for coupling the gate valve to the suitable plumbing; a detachable drive unit having a movable blade arranged therein; detachable blade seals for slidably arranging in the valve housing in order to receive the movable blade to control the flow of the medium through the gate valve and to prevent the medium from entering the drive unit; and a latching mechanism for detachably coupling both the drive unit and blade seals to and from the valve housing so as to replace either the drive unit, the blade seals, or both, without having to remove the gate valve from the suitable plumbing. | 09-25-2008 |
Hamid R. Mir, Santa Monica, CA US
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20100249842 | SPINOUS PROCESS CROSS-LINK - The present invention relates to a prosthetic spinous process cross-link for the replacement of a posterior vertebral element. The vertebral element may include a natural lamina extending from a pair of natural pedicles and a natural spinous process extending from the lamina. The prosthetic spinous process cross-link may include a first pair and a second pair of screws attached to a vertebral body and a first rod and a second rod, the first rod extending between the first pair of screws and the second rod extending between the second pair of screws. A prosthetic lamina attached to the rods is also provided, along with a prosthetic spinous process extending from the prosthetic lamina. | 09-30-2010 |
20110307012 | Spinous Process Cross-Link - A prosthetic spinous process cross-link implant for the replacement of a posterior vertebral element. The implant includes a cross link body member with a pair of adjustable link arms connected to the cross link body to size the implant to specific anatomical configurations. The implant includes a rod clamp that is spring loaded to a forward position such that capturing a spinal rod on to the adjustable link arms to achieve a snap on effect thereby increasing the ease of installation. A plurality of spinous process cross-link implants can be assembled as a kit wherein the set includes a group of spinous process type yokes and bridge type yokes each group including both fixed and variable sized implants. | 12-15-2011 |
Idris Mir, San Diego, CA US
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20100014459 | METHOD AND APPARATUS FOR MANAGING DATA SERVICES IN A MULTI-PROCESSOR COMPUTING ENVIRONMENT - Systems and methodologies are described that facilitate enhanced data service functionality for data services operating in a multi-processor computing environment. As described herein, respective processors and/or other components can be utilized to form a Smart Peripheral Subsystem (SPS). As further described herein, the SPS can operate in association with a modem processor and an application processor at a mobile computing device in order to reduce loading at the application processor and improve memory usage efficiency. In the case of a mobile computing device sharing a network connection with a tethered computing device, the SPS can couple a modem interface associated with the mobile computing device and an interface through which the disparate computing device is tethered to the mobile computing device such that operations such as Layer 2 (L2) framing and/or de-framing, Network Address Translation (NAT), or the like can be offloaded to the SPS under various circumstances. | 01-21-2010 |
20110106969 | SYSTEM AND METHOD FOR OPTIMIZING MEDIA PLAYBACK QUALITY FOR A WIRELESS HANDHELD COMPUTING DEVICE - A method for optimizing media playback quality for a wireless handheld computing device is disclosed. The system includes a client request manager that may be responsible for controlling or instructing a web browser on what file segments should be downloaded next to the wireless handheld mobile computing device to insure optimal video playback quality for the computing device. The request manager may be dynamic in that it may continually monitor elements of an application subsystem as well as the modem subsystem. The request manager may select one or more file segments for download that optimizes media playback on the wireless handheld computing device based on the data received from at least one of the application subsystem and modem subsystem. | 05-05-2011 |
20120084343 | SYSTEM AND METHOD OF PERFORMING DOMAIN NAME SERVER PRE-FETCHING - A method and system for performing domain name service (DNS) pre-fetching, content pre-fetching, or a combination thereof, are disclosed for a wireless portable computing device (PCD). The system and method may include rendering a web page on a display screen of the PCD and performing a DNS pre-fetch for any visible links within the web page. Further, the method may include determining whether a screen changing operation (i.e., a scrolling operation) is being performed and placing one or more DNS pre-fetch tasks in a queue for each link that is displayed on the display screen when the screen changing operation is performed. The method and system may reduce wait times for a wireless PCD when it is rendering webpages on its display screen. | 04-05-2012 |
20120084784 | SYSTEM AND METHOD FOR MANAGING MEMORY RESOURCE(S) OF A WIRELESS HANDHELD COMPUTING DEVICE - A method and system for managing one or more memory resources of a wireless handheld computing device is described. The method and system may include receiving a request to initiate a web browser module and receiving input for a web address. The method and system may also include receiving a file corresponding to the web address and reviewing one or more objects present within the file. The method and system may determine if an object already exists in the one or more memory resources. And if the object does not exist in the one or more memory resources, then the method and system may calculate a priority for the object. The priority of the object may then be assigned and stored. It may also be determined if the current object will exceed the threshold of the one or more memory resources, and discarding other objects with lower priority as needed. | 04-05-2012 |
20140068402 | SYSTEM AND METHOD OF PERFORMING DOMAIN NAME SERVER PRE-FETCHING - A method and system for performing domain name service (DNS) pre-fetching, content pre-fetching, or a combination thereof, are disclosed for a wireless portable computing device (PCD). The system and method may include rendering a web page on a display screen of the PCD and performing a DNS pre-fetch for any visible links within the web page. Further, the method may include determining whether a screen changing operation (i.e., a scrolling operation) is being performed and placing one or more DNS pre-fetch tasks in a queue for each link that is displayed on the display screen when the screen changing operation is performed. The method and system may reduce wait times for a wireless PCD when it is rendering webpages on its display screen. | 03-06-2014 |
Mustafa A.h. Mir, Oakland, CA US
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20140307261 | White Light Diffraction Tomography of Unlabeled Live Cells - Methods for obtaining a tomographic phase image of a specimen, either in transmission or in scatter. A specimen is illuminated by a temporally incoherent source and light collected in transmission or scattering is used to generate a scattered phase image of the specimen in multiple axial planes. The scattered field is solved for in wavevector space, and a derived instrument function is deconvolved to obtain specimen susceptibility in wavevector space. The specimen susceptibility is transformed to obtain a three-dimensional phase tomogram of the specimen. | 10-16-2014 |
Saad Mir, Burlingame, CA US
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20120131647 | System and Methods for Facilitating Secure Communications on a Website - A system and methods for facilitating secure communications on a website are presented. The system comprising a security server configured to receive a secure message from a creator device is disclosed. The security server encodes the received message and sends the encoded message or a representation of the encoded message for posting on the website so that one or more users of the website have the ability to request that the security server make the message available after the encoded message has been decoded. | 05-24-2012 |
20120317650 | SYSTEM AND METHODS FOR FACILITATING SECURE COMMUNICATIONS ON A WEBSITE - A system and methods for facilitating secure communications on a website are presented. The system comprising a security server configured to receive a secure message from a creator device is disclosed. The security server encodes the received message and sends the encoded message or a representation of the encoded message for posting on the website so that one or more users of the website have the ability to request that the security server make the message available after the encoded message has been decoded. | 12-13-2012 |
Saad Mir, Redwood City, CA US
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20120324217 | SYSTEM AND METHODS FOR FACILITATING SECURE COMMUNICATIONS ON A WEBSITE - A system and methods for facilitating secure communications on a website are presented. The system comprising a security server configured to receive a secure message from a creator device is disclosed. The security server encodes the received message and sends the encoded message or a representation of the encoded message for posting on the website so that one or more users of the website have the ability to request that the security server make the message available after the encoded message has been decoded. | 12-20-2012 |