Patent application number | Description | Published |
20090221679 | Novel HIV Targets - Using a method to measure the effect of downregulation of certain cellular proteins on HIV integration, host proteins implicated in HIV infection were identified. The identified proteins and encoding nucleic acids provide targets for inhibiting HIV infection and for evaluating the ability of compounds to inhibit HIV infection. Compounds inhibiting HIV infection include compounds targeting identified proteins and compounds targeting nucleic acids encoding the proteins. | 09-03-2009 |
20110065087 | NOVEL HIV TARGETS - A set of cellular genes that were identified by siRNA screening as being essential for Human Immunodeficiency Virus (HIV) infection. These genes are host cellular factors involved in DNA repair, specifically in the base excision repair pathway. | 03-17-2011 |
20130115227 | ANTI-ADDL MONOCLONAL ANTIBODY AND USES THEREOF - Disclosed are antibodies that bind amyloid beta-derived diffusible ligands, also known as ADDLs. The antibodies are selective for ADDLs, can penetrate the brain, and are useful in methods of detecting ADDLs and diagnosing Alzheimer's disease. The antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with ADDLs. | 05-09-2013 |
20150023952 | ANTI-ADDL MONOCLONAL ANTIBODY AND USES THEREOF - The present invention relates to antibodies that bind amyloid β-derived diffusible ligands, also known as ADDLs. The antibodies of the invention are selective for ADDLs, can penetrate the brain, and are useful in methods of detecting ADDLs and diagnosing Alzheimer's disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with ADDLs. | 01-22-2015 |
Patent application number | Description | Published |
20080266009 | Ultra-low power crystal oscillator - An ultra-low power crystal oscillator architecture that draws less than 2 μA during steady state operation. An amplifier stage is self biased and has input and output clamp circuits that limit its signal swing. Circuit values are selected such that there is sufficient transient load current for the first amplifier stage to oscillate, while at the same time the input and output clamp circuits maintain a sufficiently low swing of the stage such that the steady state average load current is on the order of less than 1 μA. | 10-30-2008 |
20090168854 | De-Emphasis Circuit for a Voltage Mode Driver Used to Communicate Via a Differential Communication Link - A circuit for de-emphasizing information transmitted via a differential communication link includes a voltage mode differential circuit and a bi-directional current source circuit. The voltage mode differential circuit includes a first and second output terminal. The voltage mode differential circuit provides a first voltage via the first output terminal and second voltage via the second output terminal in response to a differential input voltage. The bi-directional current source circuit is operatively coupled between the first and second terminals. The bi-directional current source circuit selectively provides current in a first and second direction between the first and second terminals based on the first and second voltage. | 07-02-2009 |
20100134161 | Phase Detector Circuit for Automatically Detecting 270 and 540 Degree Phase Shifts - Embodiments include implementing a phase detector for a delay-locked loop (DLL) circuit that is operable to detect substantially 270 degree and substantially 540 degree phase differences between two clock signals. In an embodiment, a DLL circuit comprises a delay line receiving a system clock signal and generating a substantially 270 degree phase shifted clock signal and a substantially 540 degree phase shifted clock signal, a phase detector receiving the system clock signal and the substantially 270 degree phase shifted clock signal, and configured to generate corresponding up and down signals upon detection of a phase shift of substantially 270 degrees between the system clock signal and the substantially 270 degree phase shifted clock signal, a charge pump coupled to the phase detector, and configured to receive the up and down signals and generate a control signal responsive to thereto, and a regulator circuit to receive the control signal from the charge pump and generate a voltage control signal to the delay chain to control delay of the system clock signal. | 06-03-2010 |
20100238598 | Electrostatic Discharge Power Clamp Trigger Circuit Using Low Stress Voltage Devices - Embodiments of an IC protection circuit that protects low voltage supply transistors and circuits within the IC from excessive power supply levels and ESD events are described. A protection circuit situated between the IO pins of the IC and the internal circuitry of the IC includes a voltage drop network and a plurality of shunt circuits to protect the IC against excessive supply voltages and ESD voltages. Each shunt circuit includes an RC trigger stage and an NMOS shunt stage that are made using low-voltage devices. A protection circuit of the embodiments includes a high voltage IO pin interface, a voltage drop network coupled to the IO pin and comprising a plurality of forward-biased diodes connected in series to drop a high voltage on the IO pin to a low voltage level, an NMOS shunt transistor coupled between the voltage drop network and a ground terminal, and a trigger circuit coupled to the NMOS shunt transistor to activate the shunt transistor when a sensed input voltage rise time is shorter than a defined supply voltage rise time. | 09-23-2010 |
20100238599 | Power Supply Equalization Circuit Using Distributed High-Voltage and Low-Voltage Shunt Circuits - Embodiments of an IC protection circuit that protects low voltage supply transistors and circuits within the IC from excessive power supply levels and ESD events are described. A protection circuit situated between the IO pins of the IC and the internal circuitry of the IC includes a voltage drop network and a plurality of shunt circuits to protect the IC against excessive supply voltages and ESD voltages, or other excessive current conditions. Each shunt circuit includes an RC trigger stage and an NMOS shunt stage that are made using low-voltage devices. A protection circuit of the embodiments includes a high voltage IO pin, a voltage drop network to drop a high voltage on the IO pin to a low voltage level on a floating voltage rail, a first shunt circuit coupled between the floating supply rail and ground, an equalizer circuit coupled between the floating supply rail and a low voltage supply rail, and a second shunt circuit coupled to the equalizer circuit through the low voltage supply rail. | 09-23-2010 |
20130057328 | PHASE DETECTOR CIRCUIT FOR AUTOMATICALLY DETECTING 270 AND 540 DEGREE PHASE SHIFTS - Embodiments include implementing a phase detector for a delay-locked loop (DLL) circuit that is operable to detect substantially 270 degree and substantially 540 degree phase differences between two clock signals. In an embodiment, a DLL circuit comprises a delay line receiving a system clock signal and generating phase shifted clock signals, a phase detector receiving the system clock signal and phase shifted clock signal, and configured to generate corresponding up and down signals upon detection of a phase shift of substantially 270 degrees between the system clock signal and the phase shifted clock signal, a charge pump coupled to the phase detector, and configured to receive the up and down signals and generate a control signal responsive to thereto, and a regulator circuit to receive the control signal from the charge pump and generate a voltage control signal to the delay chain to control delay of the system clock signal. | 03-07-2013 |
Patent application number | Description | Published |
20080242596 | BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE - Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition. | 10-02-2008 |
20100063141 | DEUTERATED BENZYLBENZENE DERIVATIVES AND METHODS OF USE - Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition. | 03-11-2010 |
20140213278 | Traffic Offload Method, Traffic Offload Function Entity and Traffic Offload System - Embodiments of the present invention provide a traffic offload method, a core network device, and a traffic offload system. The method includes: sending, user information that is of a user equipment within coverage of a first traffic offload function entity to the first traffic offload function entity; sending a traffic offload policy to the first traffic offload function entity, so that the first traffic offload function entity matches the user information with the traffic offload policy and offloads traffic corresponding to the user equipment according to the user information that successfully matches the traffic offload policy. | 07-31-2014 |
20140242994 | Network Handover Method and Apparatus - The present invention discloses a network handover method and apparatus. In the network handover method, by a base station gateway receives a handover request message or a radio link establishment request message that is sent by a source cell RNC. The base station gateway performs an access control process or initiating an access control process to a core network. | 08-28-2014 |
20150024765 | Method for Processing Message Between Micro Cell and Macro Cell, Base Station Gateway, and System - Embodiments of the present invention disclose a method and system for processing a message between a micro cell and a macro cell though a base station gateway. Embodiments solve the problems that a service message cannot be correctly processed due to a repeatedly used ID and a service process is disorderly implemented. In one embodiment the method of the present invention includes allocating a dedicated transmission channel to a micro cell base station by a base station gateway, wherein the allocation is managed by the base station gateway, and where the transmission channel performs a message transfer between the micro cell base station and a corresponding macro cell node. The method further includes transferring a message of the micro cell base station through the transmission channel. | 01-22-2015 |
20150085753 | SMALL CELL COVERAGE ADJUSTING METHOD, DEVICE, AND SYSTEM - A small cell coverage adjusting method, device, and system are disclosed. The method includes: determining whether a load of a macro cell meets a coverage parameter value adjusting condition of a small cell; and if the load of the macro cell meets the coverage parameter value adjusting condition of the small cell, sending a request message carrying a coverage parameter adjusting value to the small cell, so that after determining to accept the coverage parameter adjusting value, the small cell adjusts a current coverage parameter value of the small cell according to the coverage parameter adjusting value. By Embodiments of the present invention, a coverage parameter of the small cell can be dynamically adjusted, so that the small cell can offload services on the macro cell better, and decrease intra-frequency interference caused by the coverage of the small cell to the macro cell. | 03-26-2015 |
Patent application number | Description | Published |
20120224476 | Method and Apparatus for Maintaining Traffic Continuity - A method for maintaining traffic continuity through a Traffic Offload Function (TOF) entity includes the following steps: the TOF entity receives a downlink packet of offload traffic of a User Equipment (UE), where the downlink packet of the offload traffic is sent by a Packet Data Network (PDN); the TOF entity sends a Core Network (CN) paging message to the UE; the TOF entity receives a paging response sent by the UE to the CN, where the paging response includes a service request message of the UE; and the TOF entity forwards the service request message to the CN so that the CN sets up a Radio Access Bearer (RAB) after the service request message is received. With the method, the communication between the CN and the UE can be restored to guarantee the transmission of traffic. Accordingly, a TOF entity is also disclosed according to the present invention. | 09-06-2012 |
20120269134 | Traffic Offload Method, Traffic Offload Function Entity and Traffic Offload System - Embodiments of the present invention provide a traffic offload method, a traffic offload function entity, and a traffic offload system. The method includes: receiving, by a first traffic offload function entity, user information of a user equipment sent by a core network device; obtaining, a traffic offload policy and matching the traffic offload policy with the user information; and offloading traffic corresponding to the user equipment according to the user information that successfully matches the traffic offload policy. The traffic offload function entity may obtain the user information and may perform traffic offload according to the user information. | 10-25-2012 |
20120281543 | Dispatching Method in a CDMA System and Single Mode Chip - The present invention discloses a scheduling method in a code division multiple access system and single-mode chips, which method comprises the following steps: a single-mode chip of a terminal respectively calculating a paging slot and a paging frequency point of two subscribers with different international mobile subscriber identities of this terminal; doubling the length of a current paging period of each subscriber in the situation that the paging slots are the same and the paging frequency points are different; and scheduling two subscribers to monitor alternately within the extended paging period. The present invention facilitates the achievement of double treats in the CDMA system. | 11-08-2012 |
20130040642 | METHOD AND SYSTEM OF ALLOCATING NETWORK TEMPORARY IDENTITIES - The present invention discloses a method and system for allocating Network Temporary Identities. The method comprises: obtaining capability information of a Home NodeB; allocating information for performing identity allocation to the Home NodeB, according to the capability information; sending the allocated information for performing identity allocation to the Home NodeB, so that the Home NodeB implements network temporary identity allocation according to the information for performing identity allocation; wherein the different information for performing identity allocation corresponds to different Home NodeBs to implement the network temporary identity allocation. The technical solution disclosed by the present invention can reduce the implementation complexity of Home NodeB Gateway and the time delay. | 02-14-2013 |
20130170486 | Network searching method and device for CDMA single-mode chip multi-standby terminal - The present invention discloses a network searching method and device for a CDMA single-mode chip multi-standby terminal. The method comprises: a CDMA single-mode chip multi-standby terminal extracting Preferred Roaming Lists (PRLs) of multiple users who possess the terminal (S | 07-04-2013 |
20140018119 | METHOD, APPARATUS AND SYSTEM FOR INTERFERENCE MANAGEMENT - Disclosed in the present invention are a method, an apparatus and a system for interference management. In the embodiments of the present invention, a Home NodeB (HNB) registers in a macro cell in advance, so that a NodeB Controller (NBC) knows the information of a potential interference source HNB beforehand. Thus simply through a normal measurement and a report subsequently performed by a terminal, an interference source HNB can be found easily, and an interference management of the interference source HNB also can be performed. The solution can avoid the situation in the prior art that the interference management is performed necessarily with a cell identity of the interference source HNB obtained by the terminal. With the application of the solution, the interference management to the HNB can be performed timely and effectively and the interference experienced by the terminal from the HNB is reduced. | 01-16-2014 |
20140051479 | ELECTRONIC DEVICE WITH USB INTERFACE AND METHOD FOR STARTING USB COMMUNICATION THEREFOR - The disclosure provides an electronic device with a Universal Serial Bus (USB) interface and a method for starting USB communication for a USB interface, so as to solve the problem that a mobile phone terminal device can be damaged easily when a charger shares one interface with USB communication in the conventional art. A control pin of the control circuit of the device is connected with a VCHG pin of a power management chip; an output pin of the control circuit is connected with a USB_VBUS pin of a USB interface chip; a power pin of the control circuit is connected with a fixed voltage input end which inputs a high level; and the control circuit is configured to output a fixed voltage from the output pin of the control circuit when detecting that the voltage of the control pin is more than a set threshold and output a low level from the output pin of the control circuit when detecting that the voltage of the control pin is less than the set threshold. The charging voltage (VCHG) of the handheld terminal product is only used as the control signal which is isolated from the voltage output to the USB_VBUS pin, so that the damage to the device is avoided. | 02-20-2014 |
20140059363 | Electronic device having USB interface and method for starting USB communication with such device - The present disclosure provides an electronic device having a USB interface and a method for starting USB communication with such an electronic device, so as to solve the problem of a risk of damaging a mobile phone terminal device arising from sharing of an interface by a charger and a USB communication cable in the related art. In the electronic device, a port GPIO of a baseband chip is connected to a pin USB_VBUS of a USB interface of the baseband chip; based on this circuit, a power management chip detects a state of plugging-in-or-pulling-out of the charger and generates a corresponding interrupt request; and the baseband chip controls the GPIO to output a corresponding level according to the interrupt request. By connecting the port GPIO and the pin USB_VBUS and controlling an output level of GPIO with a software, a high level or a low level (as a triggering signal for starting or terminating the USB communication) is input to the pin USB_VBUS, thus avoiding damage to the device. | 02-27-2014 |