Miller-Moslin
Karen Miller-Moslin, Cambridge, MA US
Patent application number | Description | Published |
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20100041663 | Organic Compounds as Smo Inhibitors - The present invention relates generally to novel compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders. The present invention includes novel compounds, novel compositions, methods of their use and methods of their manufacture, where such compounds are generally pharmacologically useful as agents in therapies whose mechanism of action involve methods of inhibiting tumorigenesis, tumor growth and tumor survival using agents that inhibit the Hedgehog and Smo signaling pathway. | 02-18-2010 |
20100069368 | Organic Compounds and Their Uses - The present disclosure relates to compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders; specifically relating to compounds of formula I: | 03-18-2010 |
Karen Miller-Moslin, Princeton, NJ US
Patent application number | Description | Published |
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20120165298 | SULFONAMIDE COMPOUNDS - The present invention includes novel compound and methods of treating a disease or disorder by antagonizing Bcl-2 family proteins, particularly compounds of formula (I): | 06-28-2012 |
20120289507 | ORGANIC COMPOUNDS AS SMO INHIBITORS - The present invention relates generally to novel compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders. The present invention includes novel compounds, novel compositions, methods of their use and methods of their manufacture, where such compounds are generally pharmacologically useful as agents in therapies whose mechanism of action involve methods of inhibiting tumorigenesis, tumor growth and tumor survival using agents that inhibit the Hedgehog and Smo signaling pathway. | 11-15-2012 |
Karen Marie Miller-Moslin, Princeton, NJ US
Patent application number | Description | Published |
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20130261299 | PYRIDAZINYL DERIVATIVES AS SMO INHIBITORS - The present invention relates to compounds of formula I: | 10-03-2013 |
20150025070 | NOVEL 2-PIPERIDIN-1-YL-ACETAMIDE COMPOUNDS FOR USE AS TANKYRASE INHIBITORS - The present invention provides for compounds of formula (I): | 01-22-2015 |