Patent application number | Description | Published |
20080319404 | Microneedle Devices - Microneedles and microarrays comprising such microneedles are described. The microneedles comprise: a base; a shaft portion extending from the base to a second end distal from the base; a microblade structure extending from the second end; capillary spaces associated with the microblade structure; and a coating in the capillary spaces, the coating comprising an active component. The invention also provides a method for delivering an active component through mammalian skin, comprising: applying the medical device to mammalian skin so that the at least one microneedle is inserted through the stratum corneum and the active component is exposed to interstitial fluids; and allowing the at least one microneedle to remain inserted through the stratum corneum for a sufficient amount of time to dissolve the active component. In another aspect, the invention provides a method for applying an active component to a microneedle, comprising: providing a microneedle, comprising: a base, a shaft portion extending from the base to a second end distal from the base, a microblade structure extending from the second end, and capillary spaces associated with the microblade structure; applying a liquid coating to at least the microblade structure of the microneedle, the liquid coating comprising an active component; and drying the liquid coating to provide a dried coating of active component, the dried coating located at least within the capillary spaces of the microblade structure. | 12-25-2008 |
20090053448 | Protective Films and Related Methods - The invention features protective film constructions that may be used, for example, as a protective floor finish. | 02-26-2009 |
20090099537 | PROCESS FOR MAKING MICRONEEDLES, MICRONEEDLE ARRAYS, MASTERS, AND REPLICATION TOOLS - A process for making a microneedle array master comprises: (a) providing a photoreactive composition, the photoreactive composition comprising: (1) at least one reactive species that is capable of undergoing an acid- or radical-initiated chemical reaction, and (2) at least one multiphoton photoinitiator system; and (b) imagewise exposing at least a portion of the composition to light sufficient to cause simultaneous absorption of at least two photons, thereby inducing at least one acid- or radical-initiated chemical reaction where the composition is exposed to the light, the imagewise exposing being carried out in a pattern that is effective to define at least the surface of a plurality of microneedles. The microneedles may be solid and the outer surface of the microneedles may be characterized by at least one concave area. The master may be used to fabricate a tool for replication. | 04-16-2009 |
20090261499 | DIE HAVING MULTIPLE ORIFICE SLOT - The invention is a die for dispensing flowable material. The die is comprised of a die block. An external face is disposed on the die block. At least one slot extends perpendicularly into the external face. The slot has a longitudinal dimension, a first longitudinal side and a second longitudinal side. At least one support member extends from the external surface into the slot. The support member extends continuously from the first longitudinal side to the second longitudinal side. At least a portion of the support member is disposed in a direction other than perpendicular to the longitudinal dimension. The support member is disposed to such that at least a portion of any plane extending from the first longitudinal side to the second longitudinal side, in a direction perpendicular to the longitudinal dimension of the slot, passes through a void area. | 10-22-2009 |
20100024671 | SOLVENT-ASSISTED EMBOSSING OF FLEXOGRAPHIC PRINTING PLATES - Methods of forming a flexographic printing plate are described and include disposing a polymeric substrate onto a master tool having a plurality of recesses defining a master tool pattern. A solvent is disposed within the recesses. Then, the solvent is diffused into the polymeric substrate to form a substrate relief pattern that is complementary to the master pattern. The substrate relief pattern is then cured to form a flexographic printing plate. Flexographic printing plates are also described. | 02-04-2010 |
20100077932 | SOLVENT REMOVAL ASSISTED MATERIAL TRANSFER FOR FLEXOGRAPHIC PRINTING - Methods and systems for flexographic printing are discussed. The methods include removing solvent from a material to be transferred from a donor substrate to a feature of a flexographic printing plate. Solvent is removed from the material prior to transfer to the feature, resulting in improved transfer of the material to the feature. The systems include solvent removal apparatuses for facilitating removal of solvent from the material. | 04-01-2010 |
20110048621 | METHOD OF FORMING COMPOSITE OPTICAL FILM - Methods of forming composite optical film ( | 03-03-2011 |
20110088841 | APPARATUS AND METHOD OF IMPREGNATING FIBROUS WEBS - The present disclosure relates to an apparatus and method of impregnating fibrous webs. An apparatus generally includes a volume of liquid curable resin having a liquid surface, and a liquid curable resin ( | 04-21-2011 |
20110100957 | METHOD OF FORMING A PATTERNED SUBSTRATE - A method of forming a petterned substracte is provided. The method includes providing a substrate ( | 05-05-2011 |
20110111182 | METHOD OF FORMING A MICROSTRUCTURE - The present disclosure describes an article and a method of forming a microstructure. The method includes providing a substrate having a structured surface region comprising one or more recessed features with recessed surfaces. The structured surface region is substantially free of plateaus. The method includes disposing a fluid composition comprising a functional material and a liquid onto the structured surface region. The method includes evaporating liquid from the fluid composition. The functional material collects on the recessed surfaces such that a remainder of the structured surface region is substantially free of the functional material. | 05-12-2011 |
20110126730 | SOLVENT ASSISTED METHOD OF MICROCONTACT PRINTING - A method of microcontact printing comprises (a) providing an elastomeric stamp comprising a printing surface inked with an ink comprising surface-functionalizing molecules, (b) treating the inked printing surface of the stamp with solvent, and (c) contacting the treated inked printing surface of the stamp to a surface of a substrate. The printing surface of the stamp comprises a first relief pattern, or the surface of the substrate comprises a second relief pattern, or both of the surfaces comprise the relief patterns, and a pattern of surface-functionalizing molecules is transferred to the substrate according to one or both of the relief patterns. | 06-02-2011 |
20110151199 | NEEDLE COATING AND IN-LINE CURING OF A COATED WORKPIECE - A method for coating a work piece with resin including applying a controlled volume of liquid resin to the work piece with an applicator and allowing consecutive streams of resin to meld together to form a self leveling surface. The resin can be actively or passively cured. The work piece can be planar or cylindrical. | 06-23-2011 |
20110192977 | APPARATUS AND METHODS FOR ALTERING CHARGE ON A DIELECTRIC MATERIAL - Methods of altering charge on a dielectric material involve application of an at least weakly conductive liquid to at least a portion of the dielectric material. The liquid is then at least partially removed from the dielectric material leaving a substantially uniform electrostatic charge on at least the portion of the dielectric material. Some methods provide a dielectric material that is both net neutral and completely neutral. Other methods generate a charge pattern that is used for subsequent processing. | 08-11-2011 |
20120038984 | RETROREFLECTIVE SHEETING INCLUDING A LOW INDEX COATING - Retroreflective articles and constructions are disclosed. One exemplary retroreflective article or construction includes a retroreflective layer and a low refractive index layer. In one exemplary embodiment, the low refractive index layer is adjacent to at least a portion of a retroreflective structured major surface of the retroreflective layer. | 02-16-2012 |
20120137911 | FLEXOGRAPHIC PRINTING WITH CURING DURING TRANSFER TO SUBSTRATE - Methods and systems for flexographic printing are described and include curing of material to be printed while the material is in contact with both a feature of a flexographic printing plate and a recipient substrate. The systems and method are useful in preventing slippage between the feature and the recipient substrate, and are particularly useful when printing at high resolution. | 06-07-2012 |
20120247355 | APPARATUS AND METHOD FOR MICROCONTACT PRINTING USING A PRESSURIZED ROLLER - An apparatus and method for microcontact printing are described. The microcontact printing apparatus includes a planar stamp and a pressurized roller. The pressurized roller includes an inflatable bladder that can be inflated by a fluid to a pressure that reduces printing defects such as voids and stamp collapse. A substrate is disposed between the pressurized roller and a stamp coated with an ink of functionalizing molecules. As the pressurized roller moves over the substrate, at least a portion of the functionalizing molecules are transferred from the stamp to the substrate in the desired pattern. | 10-04-2012 |
20130004749 | SURFACE-MODIFIED ADHESIVES - Surface-modified adhesives may be prepared by contacting an adhesive layer to an at least partially discontinuous layer on a releasing substrate and removing the adhesive layer such that at least a portion of the at least partially discontinuous layer adheres to the adhesive surface. The modified adhesive surface remains an adhesive surface. The modified adhesive layer can be used to prepare adhesive articles, including articles containing multiple surface-modified adhesive layers. | 01-03-2013 |
20130034682 | RETROREFLECTIVE ARTICLES INCLUDING OPTICALLY ACTIVE AREAS AND OPTICALLY INACTIVE AREAS - This disclosure generally relates to retroreflective articles and methods of making such articles. | 02-07-2013 |
20130068723 | Method of Using a Mask to Provide a Patterned Substrate - A method of producing substrates having a patterned mask layer with fine features such as repeating stripes. The method including the steps of forming a substrate having a transfer layer with a predetermined pattern on a first major surface of the substrate; providing the substrate having the transfer layer on the first major surface; providing a structured tool having a body and a plurality of contact portions, the contact portions having a Young's Modulus between about 0.5 Gpa to about 30 Gpa; heating either the structured tool or the substrate; contacting the transfer layer with the structured tool; cooling the transfer layer; and withdrawing the structured tool from the transfer layer such that portions of the transfer layer separate with the structured tool leaving openings in the transfer layer that extend all the way through the transfer layer to the substrate forming the transfer layer with the predetermined pattern. | 03-21-2013 |
20130114142 | RETROREFLECTIVE ARTICLES INCLUDING OPTICALLY ACTIVE AREAS AND OPTICALLY INACTIVE AREAS - This disclosure generally relates to retroreflective articles and methods of making such articles. | 05-09-2013 |
20130243972 | NEEDLE COATING AND IN-LINE CURING OF A COATED WORKPIECE - A method for coating a work piece with resin including applying a controlled volume of liquid resin to the work piece with an applicator and allowing consecutive streams of resin to meld together to form a self leveling surface. The resin can be actively or passively cured. The work piece can be planar or cylindrical. | 09-19-2013 |
20130251945 | IMAGES AND METHOD OF MAKING THE SAME - An article having a first major surface with at least first and second regions, the first region comprising a plurality of first structures having a first surface roughness, the second region comprising a plurality of second structures having a second surface roughness, wherein at least a portion of the at least first and second regions have a surface roughness difference between them that together exhibit at least a portion of a first image. Exemplary uses of the articles include tool-less macro-patterning of transflectors, customized appearance for retroreflective sheeting, incorporation of security features, decorative patterns for lighting diffusers, images or logos in medical films without inks or contamination. | 09-26-2013 |
20140071653 | BACK-LIT TRANSMISSIVE DISPLAY HAVING VARIABLE INDEX LIGHT EXTRACTION LAYER - This application describes a back-lit transmissive display including a transmissive display ( | 03-13-2014 |
20140102327 | APPARATUS AND METHOD FOR MICROCONTACT PRINTING ON INDEFINITE LENGTH WEBS - An apparatus and a method for micro-contact printing on a substrate. A roll having very low drag is supported for rotation by air bearings and has a micro-contact printing stamp mounted to its outer surface. Contact between the substrate and the micro-contact printing stamp drives the roll and repeatedly imprints the pattern onto the web. In convenient embodiments, the roll is a sleeve positioned over a core with the sleeve supported for rotation by a layer of air between the sleeve and the core. | 04-17-2014 |
20140110879 | METHOD FOR MAKING, INKING, AND MOUNTING STAMPS FOR MICRO-CONTACT PRINTING - A method of preparing a patterned micro-contact printing stamp for micro contact printing including the making of a submaster of e.g. epoxy, against which a micro-contact printing stamp from polydimethylsiloxane or other stamp forming material can be formed. The micro-contact printing stamp can then be exposed to an inking material while the micro-contact printing stamp is still against the submaster, resulting in a micro-contact printing stamp capable of making numerous impressions before the inking material is exhausted. | 04-24-2014 |
20140199523 | METHOD OF FORMING A MICROSTRUCTURE - The present disclosure describes an article and a method of forming a microstructure. The method includes providing a substrate having a structured surface region comprising one or more recessed features with recessed surfaces. The structured surface region is substantially free of plateaus. The method includes disposing a fluid composition comprising a functional material and a liquid onto the structured surface region. The method includes evaporating liquid from the fluid composition. The functional material collects on the recessed surfaces such that a remainder of the structured surface region is substantially free of the functional material. | 07-17-2014 |
20150043074 | RETROREFLECTIVE ARTICLES INCLUDING A SECURITY MARK - The present disclosure relates to prismatic retroreflective articles that includes a security mark and to methods of making such articles. | 02-12-2015 |