Michlitsch
Ken Michlitsch, Livermore, CA US
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20100211086 | APPARATUS AND METHODS FOR FORMING AND SECURING GASTROINTESTINAL TISSUE FOLDS - Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point and moving the first tissue contact point from a position initially distal to, or in line with, a second tissue contact point to a position proximal of the second contact point, thereby forming the tissue fold, and extending an anchor assembly through the tissue fold from a vicinity of the second tissue contact point. Adjustable anchor assemblies; as well as anchor delivery systems, shape-lockable guides and methods for endoluminally performing medical procedures, such as gastric reduction, treatment of gastroesophageal reflux disease, resection of lesions, and treatment of bleeding sites; are also provided. | 08-19-2010 |
Kenneth Michlitsch, Livermore, CA US
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20110098708 | POWERED TISSUE MODIFICATION DEVICES AND METHODS - A device for modifying tissue in a spine may include: a shaft having a proximal portion and a distal portion, the distal portion having dimensions which allow it to be passed into an epidural space of the spine and between target and non-target tissues; at least one distal force application member extending from the distal portion of the shaft and configured to facilitate application of at least one of anchoring force and tensioning force to the shaft; at least one movable tissue modifying member coupled with the shaft at or near its distal portion; at least one drive member coupled with the at least one tissue modifying member to activate the at least one tissue modifying member; and at least one power transmission member coupled with the at least one drive member to deliver power to the at least one drive member. | 04-28-2011 |
Kenneth J. Michlitsch, Berwyn, PA US
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20120264116 | METHODS AND APPARATUS FOR POINT-OF-CARE NUCLEIC ACID AMPLIFICATION AND DETECTION - Methods and apparatus are provided for point-of-care nucleic acid amplification and detection. One embodiment of the invention comprises a fully integrated, sample-to-answer molecular diagnostic instrument that optionally may be used in a multiplexed fashion to detect multiple target nucleic acid sequences of interest and that optionally may be configured for disposal after one-time use. Optionally, sample preparation is fully or partially achieved via heat treatment and/or using a filter paper, such as a chemically treated filter paper, e.g., an FTA card. The instrument preferable utilizes an isothermal nucleic acid amplification technique, such as loop-mediated isothermal amplification (LAMP), to reduce the instrumentation requirements associated with nucleic acid amplification. Detection of target amplification may be achieved, for example, via detection of a color shift or fluorescence in a dye added to the amplification reaction. | 10-18-2012 |
20130304054 | METHODS AND APPARATUS FOR PERFORMING RENAL NEUROMODULATION VIA CATHETER APPARATUSES HAVING INFLATABLE BALLOONS - Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided. | 11-14-2013 |
20130304064 | METHODS AND APPARATUS FOR PERFORMING RENAL NEUROMODULATION VIA CATHETER APPARATUSES HAVING INFLATABLE BALLOONS - Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided. | 11-14-2013 |
20140356874 | METHODS AND APPARATUS FOR POINT-OF-CARE NUCLEIC ACID AMPLIFICATION AND DETECTION - Methods and apparatus are provided for point-of-care nucleic acid amplification and detection. One embodiment of the invention comprises a fully integrated, sample-to-answer molecular diagnostic instrument that optionally may be used in a multiplexed fashion to detect multiple target nucleic acid sequences of interest and that optionally may be configured for disposal after one-time use. The instrument preferable utilizes an isothermal nucleic acid amplification technique, such as loop-mediated isothermal amplification (LAMP), to reduce the instrumentation requirements associated with nucleic acid amplification. Detection of target amplification may be achieved, for example, via detection of a color shift or fluorescence in a dye added to the amplification reaction. Such detection may be performed visually by an operator or may be achieved utilizing an imaging technique, e.g., spectrophotometric imaging. | 12-04-2014 |
Matthew P. Michlitsch, Torrance, CA US
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20100325008 | METHODS FOR TRANSFORMING AN AUCTIONED ITEM OF UNKNOWN VALUE AND BUYER INTO AN AUCTIONED ITEM OF KNOWN VALUE AND BUYER - Methods, including methods conducted with a computer system and/or over a telecommunications network, are provided for transforming an auctioned item of unknown value and buyer into an auctioned item of known value and buyer. The methods comprise sealed bid, second-best price auctions that diminish the effects of information asymmetry while aligning the interests of buyers and sellers by reducing common auction risks of the winner's curse, buyer's remorse, bid shading, shill bidding, bid sniping, and/or collusion. Bidders submit sealed bids for the auctioned item. At a successful auction's conclusion, a highest bidder is established as the item's buyer and a second-best price is established as the value. This second-best price is the second highest sealed bid obtained, or a reserve price that the highest bidder accepts as the value for the auctioned item when the highest sealed bid is the only sealed bid at least equal to the reserve price. The second-best price optionally may be one bid increment more than the second highest sealed bid or the reserve price. | 12-23-2010 |
Rita J. Michlitsch, Grand Haven, MI US
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20080257057 | Device for fatigue testing an implantable medical device - A device for fatigue testing an implantable medical device having a compression assembly and a first bending assembly. The compression assembly supports first and second portions of the implantable medical device so as to apply a compression force to the implantable medical device along a compression axis and at a compression angle. The first bending assembly is configured to apply a first bending force onto the implantable medical device to move the first portion of the implantable medical device about a first bending axis with respect to the second portion of the implantable medical device. The first bending assembly is coupled with the compression assembly such that the compression angle remains substantially constant regardless of the position of the first portion of the implantable medical device with respect to the second portion of the implantable medical device. | 10-23-2008 |