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Michelin

Jean-Luc Michelin, Bois Colombes FR

Patent application numberDescriptionPublished
20090141290Optical Measuring Device Using Optical Triangulation - An optical triangulation measuring device includes an emmiter that emits two alternating light beams with different wavelengths along the same path; a beam splitter; an optical separator that directs the alternating split beams towards the surfaces from which they are reflected; an optical combiner that collects the beams and directs them along a path; optronic sensors that receive two light images and to deliver a signal indicating the position of the energy barycenter a time synchronizer for the two alternating beams and the two images on the optronic sensors; and a processor for processing the signals from the optronic sensors in order to supply information relating to the position and inclination of the surface.06-04-2009

Olivier Michelin, Lausanne CH

Patent application numberDescriptionPublished
20110112282IDO INHIBITORS AND THERAPEUTIC USES THEREOF - Compounds of formula (I), and pharmaceutically acceptable salts thereof, in which each compound is adapted to occupy the binding site of human IDO, which comprises a large hydrophobic pocket A and a second, proximal hydrophobic pocket B, the compound comprising at least one of the following elements: (i) a large hydrophobic fragment to substantially fill pocket A in the binding site of human IDO; (ii) an atom that can coordinate to the heme iron of human IDO, (iii) a positively charged group that can form a salt-bridge with the heme 7-propionate of the human IDO; (iv) a negatively charged group that can form a salt-bridge with Arg231 of the human IDO; (v) a hydrophobic group that can form van der Waals interactions with pocket B; and (vi) one or more substituents that can hydrogen bond to Ser167 and to Gly262, and as IDO inhibitors and their therapeutic use, eg in the treatment of cancer.05-12-2011

Philippe Michelin, Paris FR

Patent application numberDescriptionPublished
20110178794METHODS AND SYSTEMS FOR INTERPRETING TEXT USING INTELLIGENT GLOSSARIES - A computer implemented method used to interpret text, including from a set of formal glossaries which may refer one to the other and are intended to define precisely the terminology of a field of endeavor. Such glossaries are known as intelligent, in the sense that they allow machines to make deductions, without the need for human intervention. However, they may also accept human intervention. Once a word is defined in an intelligent glossary, all the logical consequences of the use of that word in a formal and well-formed sentence are computable. The process includes a question and answer mechanism, which applies the definitions contained in the intelligent glossaries to a given formal sentence. The methods may be applied in the development of knowledge management methods and tools that are based on semantics; for example: modeling of essential knowledge in the field based on the relevant semantics.07-21-2011