Michaud, MA
Avida Michaud, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20150314454 | APPARATUS AND METHODS FOR PROVIDING A PERSISTENT COMPANION DEVICE - A development platform for developing a skill for a persistent companion device (PCD) includes an asset development library having an application programming interface (API) configured to enable a developer to at least one of find, create, edit and access one or more content assets utilizable for creating a skill, an expression tool suite having one or more APIs via which are received one or more expressions associated with the skill as specified by the developer wherein the skill is executable by the PCD in response to at least one defined input, a behavior editor for specifying one or more behavioral sequences of the PCD for the skill and a skill deployment facility having an API for deploying the skill to an execution engine of the PCD. | 11-05-2015 |
Christopher J. Michaud, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20150126335 | HEIGHT ADJUSTABLE PULL-UP BAR APPARATUS - A removably mountable, height adjustable pull-up bar allows the device to be rapidly mounted at a number of different heights to the pair of vertical support members. The pull-up bar interconnects a pair of brackets, the top end of each bracket containing a pin which slides into apertures on the sides of each vertical support member from a first direction while the bottom end of each bracket includes a U-shaped member which may be clamped around the front and/or sides of a vertical support member and secured thereto. | 05-07-2015 |
Corinne Michaud, Salem, MA US
Patent application number | Description | Published |
---|---|---|
20090098581 | Tyrosine phosphorylation sites - The invention discloses 482 novel phosphorylation sites identified in carcinoma and/or leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above. | 04-16-2009 |
Dennis Michaud, Waltham, MA US
Patent application number | Description | Published |
---|---|---|
20130133273 | Foldable Building Units - Foldable building units are provided based on structural frame and connection assembly designs that enable greater construction efficiency and flexibility. The structural frame and connection assembly designs allow for easier connection of frame elements in the prefabrication process of the foldable building units and for easier connection of frame elements at the building site, for example, of foldably connected frame elements after unfolding. They also allow for more finish in the pre-fabrication process, and/or less and faster work at the building site, for example, by enabling conventional structural lumber grids that can be continuous through the edges and corners of the building envelope for conventional exterior finishing, while providing a tight building envelope with reduced heat transfer, particularly, through the edges of the foldable building unit. | 05-30-2013 |
Dennis Michaud, Somerville, MA US
Patent application number | Description | Published |
---|---|---|
20140095122 | METHOD, APPARATUS AND SYSTEM FOR CUSTOMIZING A BUILDING VIA A VIRTUAL ENVIRONMENT - A configurator platform and a corresponding configurator environment, according to an embodiment of the invention enable a user to navigate a displayed virtual representation of a building configuration. The user is also enabled to customize the building configuration. The customization is based on a set of physical product specifications from which the user may make selections. A building configuration may be stored as a plurality of tags indicative of physical product specifications included in the building configuration. The building configuration may be sent to an engineering system where it is translated into an engineering model of the building. The configuration platform may further provide interaction with a geographic information system to provide environmental, geologic, and regulatory information as well as other location-based data associated with the geographic location of the building. | 04-03-2014 |
Dennis Michaud, Groton, MA US
Patent application number | Description | Published |
---|---|---|
20140059947 | Buildings Formed From Complementary Building Modules, And Methods For Building Same - Buildings are described that incorporate at least a folding building module and a complementary building module that also can be a folding building module. The building modules can be shipped to the building site separately and can be unfolded and connected quickly. The described foldable houses and buildings exhibit more design flexibility, are formed from easily transported building modules, and/or allow folded building modules that are substantially in finished condition. Additionally, methods for forming the buildings and houses are described. | 03-06-2014 |
Dennis Paul Michaud, Dracut, MA US
Patent application number | Description | Published |
---|---|---|
20110137022 | METHOD FOR THE ANALYSIS OF OLIGONUCLEOTIDES - A method for the analysis of oligonucleotides is provided. The method comprises: desalting a mixture of oligonucleotides under conditions such that there is substantially no separation of the mixture of oligonucleotides, and/or by on-line desalting, introducing the desalted mixture of oligonucleotides into a mass spectrometer; and quantifying one or more oligonucleotides comprised in the mixture by mass spectrometry. | 06-09-2011 |
Dennis R. Michaud, Cambridge, MA US
Patent application number | Description | Published |
---|---|---|
20120279142 | FOLDABLE BUILDING UNITS - Prefabricated foldable building units are described that have one or more of the following advantages. They are more easily prefabricated, more easily transported to building sites without requiring special permits, unloadable and unfoldable at the building sites without using cranes (they can be unloaded using ground-level lifting rigs and unfolded using, for example, a cable mechanism), allow precise and fast completion at the building site, and allow significant reduction in the scope of work to be completed on-site, where costs and scheduling are far less manageable. Further, methods for unloading and unfolding foldable building units are described that obviate the need for one or more cranes that can be expensive and project-complicating, thereby opening up a significant percentage of building sites for placement of prefabricated foldable building units. | 11-08-2012 |
Devin T. Michaud, Billerica, MA US
Patent application number | Description | Published |
---|---|---|
20140342447 | CASSETTE FOR STERILITY TESTING - The invention provides a device for growing cells—referred to as a cassette. The cell culturing device includes a housing that contains a lid having an optically clear window; a fluid distribution channel; a sample injection port fluidically connected to the fluid distribution channel; a base housing a porous media pad; and a media injection port fluidically connected to the media pad. The lid mates to the base to form a sterile seal; the fluid distribution channel is disposed over the media pad, which is viewable through the optical window; and sample fluid introduced into the fluid distribution channel is distributed evenly to the media pad, e.g., via a plurality of channels. The invention also provides kits that include cassettes of the invention and a tube set. | 11-20-2014 |
Donald A. Michaud, Marblehead, MA US
Patent application number | Description | Published |
---|---|---|
20080271413 | Compresent insulation arrangement for building openings - A window frame insulation assembly and sealing arrangement, comprising an elongated, extruded block of foam material having a first or inner side and a second or outer side. A unitary air fin is co-extruded therewith. The air fin comprises an elongated flange of flexible foam material. The air fin and the elongated block define an elongated receiving-channel that is filled with a foam compression rod there between creating a seal for blocking air and moisture from a building in which said window frame assembly has been placed. | 11-06-2008 |
20110067349 | Compresent insulation arrangement for building openings - A window frame insulation assembly and sealing arrangement, comprising an elongated, extruded block of foam material having a first or inner side and a second or outer side. A unitary air fin is co-extruded therewith. The air fin comprises an elongated flange of flexible foam material. The air fin and the elongated block define an elongated receiving-channel that is filled with a foam compression rod there between creating a seal for blocking air and moisture from a building in which said window frame assembly has been placed. | 03-24-2011 |
20130008106 | Transition assemblies for building opening - A sealing assembly for securely and insulatively maintaining a window or door and surrounding frame arrangement within an opening of a building wall. The sealing assembly comprises an elongated foam cell body member arranged within a channel of the surrounding frame arrangement of the window or door, wherein the elongated cell body member has a wall-opening-facing side. An elongated caulking band flange member is arranged in abutting relationship with a corner of the elongated foam cell body member. A thin flexible air fin is arranged in close environmental sealing relationship with the elongated foam cell body member and the opening in the wall of the building. A securement member is arranged to fasten the window or door surrounding frame arrangement, the elongated foam cell body member and the air fin, all to the building wall opening. | 01-10-2013 |
Francis P Michaud, Hudson, MA US
Patent application number | Description | Published |
---|---|---|
20110092838 | QT INTERVAL MONITORING SYSTEM WITH ALARMS AND TRENDING - An ECG monitoring system continuously monitors a patient's ECG waveform and periodically identifies the patient's QT interval. QT interval values are averaged over time and a corrected interval value QTc and a change in QTc relative to a baseline, dQTc, are periodically produced. An alarm is responsive to updated QT interval values and issues an alarm whenever a selected QT value exceeds an alarm limit. The periodically produced QT interval values are stored and a trend display may be produced showing changes in the QT interval information over different periods of time. The trend display may selectively display the trend information either graphically or in tabular form. | 04-21-2011 |
Gregory Allen Michaud, Stow, MA US
Patent application number | Description | Published |
---|---|---|
20100151484 | KINASE AND UBIQUINATION ASSAYS - Compositions, including antibodies, polypeptides, and organic molecules, kits, and methods for probing molecular interactions (e.g., deubiquination, ubiquination and kinase activity), e.g., using resonance energy transfer (RET) are provided. | 06-17-2010 |
Neil Michaud, Waltham, MA US
Patent application number | Description | Published |
---|---|---|
20100196388 | TARGETED BINDING AGENTS DIRECTED TO SONIC HEDGEHOG HOMOLOG AND USES THEREOF - The invention relates to targeted binding agents against human sonic hedgehog homolog (Shh) and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to Shh. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of Shh and as diagnostics. | 08-05-2010 |
20120328625 | TARGETED BINDING AGENTS DIRECTED TO SONIC HEDGEHOG HOMOLOG AND USES THEREOF - The invention relates to targeted binding agents against human sonic hedgehog homolog (Shh) and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to Shh. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of Shh and as diagnostics. | 12-27-2012 |
Richard O. Michaud, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20080288420 | Portfolio Optimization by Means of Meta-Resampled Efficient Frontiers - A computer-implemented method and computer program product for selecting a portfolio weight (subject to specified constraints) for each of a plurality of assets of an optimal portfolio. A mean-variance efficient frontier is calculated based on input data characterizing the defined expected return and the defined standard deviation of return of each of the plurality of assets. Multiple sets of optimization inputs are drawn from a distribution of simulated optimization inputs consistent with the defined expected return, the defined standard deviation of return of each of the plurality of assets and then a simulated mean-variance efficient frontier is computed for each set of optimization inputs. A meta-resampled efficient frontier is determined as a statistical mean of associated portfolios among the simulated mean-variance efficient frontiers, and a portfolio weight is selected for each asset from the meta-resampled efficient frontier according to a specified investment objective. The number of simulations and the number of simulation periods is determined on the basis of a specified level of forecast certainty. | 11-20-2008 |
20120116994 | Dynamic Portfolio Monitoring - Michaud rebalance probabilities are renormalized in the case of successive datasets, historical or simulated, where partial commonality of information is imputed to the two datasets. Two separate sets of optimization inputs correspond to a stochastic process and optimization subject to a set of constraints making the optimization analytically intractable. A subset of data drawn on the basis the first optimization input is recursively replaced with data sampled from the second optimization input, the extent of replacement governed by the extent of common information. A set of rebalance probabilities is calculated, and the L | 05-10-2012 |
20120246095 | Resampled Efficient Frontiers for Portfolios with Derivative Overlays - Computer-implemented methods for constructing a risk-return optimal allocation to a set of assets, where a subset of the assets is at least partially insured or modified by the addition of derivative securities. The methods entail resampling a plurality of sets of returns consistent with a return distribution for each asset, with at least one asset modified by a derivative overlay, subject to terms of at least one contract requirement. A statistical mean of associated optimal portfolios is established, generating a resampled efficient frontier, on the basis of which a portfolio weight is selected for each asset according to a specified risk objective. | 09-27-2012 |
20140289163 | Method and Computer Program for Minimizing Trading Costs Subject to a Probability Criterion of Optimality Acceptability - Embodiments model a series of partial trades on an investment portfolio to reduce the optimality discrepancy relative to a target optimal portfolio, and determine whether a partially rebalanced portfolio along the trading path is within a predefined threshold of statistical optimality relative to the target optimal portfolio. Certain embodiments maximize the impact of partial rebalancing of a portfolio by maximizing reduction of an optimality discrepancy while minimizing the trade cost function along the trading path from the initial portfolio toward the target optimal portfolio. | 09-25-2014 |
Robert Michaud, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20080288420 | Portfolio Optimization by Means of Meta-Resampled Efficient Frontiers - A computer-implemented method and computer program product for selecting a portfolio weight (subject to specified constraints) for each of a plurality of assets of an optimal portfolio. A mean-variance efficient frontier is calculated based on input data characterizing the defined expected return and the defined standard deviation of return of each of the plurality of assets. Multiple sets of optimization inputs are drawn from a distribution of simulated optimization inputs consistent with the defined expected return, the defined standard deviation of return of each of the plurality of assets and then a simulated mean-variance efficient frontier is computed for each set of optimization inputs. A meta-resampled efficient frontier is determined as a statistical mean of associated portfolios among the simulated mean-variance efficient frontiers, and a portfolio weight is selected for each asset from the meta-resampled efficient frontier according to a specified investment objective. The number of simulations and the number of simulation periods is determined on the basis of a specified level of forecast certainty. | 11-20-2008 |
20120116994 | Dynamic Portfolio Monitoring - Michaud rebalance probabilities are renormalized in the case of successive datasets, historical or simulated, where partial commonality of information is imputed to the two datasets. Two separate sets of optimization inputs correspond to a stochastic process and optimization subject to a set of constraints making the optimization analytically intractable. A subset of data drawn on the basis the first optimization input is recursively replaced with data sampled from the second optimization input, the extent of replacement governed by the extent of common information. A set of rebalance probabilities is calculated, and the L | 05-10-2012 |
20120246095 | Resampled Efficient Frontiers for Portfolios with Derivative Overlays - Computer-implemented methods for constructing a risk-return optimal allocation to a set of assets, where a subset of the assets is at least partially insured or modified by the addition of derivative securities. The methods entail resampling a plurality of sets of returns consistent with a return distribution for each asset, with at least one asset modified by a derivative overlay, subject to terms of at least one contract requirement. A statistical mean of associated optimal portfolios is established, generating a resampled efficient frontier, on the basis of which a portfolio weight is selected for each asset according to a specified risk objective. | 09-27-2012 |
20140289163 | Method and Computer Program for Minimizing Trading Costs Subject to a Probability Criterion of Optimality Acceptability - Embodiments model a series of partial trades on an investment portfolio to reduce the optimality discrepancy relative to a target optimal portfolio, and determine whether a partially rebalanced portfolio along the trading path is within a predefined threshold of statistical optimality relative to the target optimal portfolio. Certain embodiments maximize the impact of partial rebalancing of a portfolio by maximizing reduction of an optimality discrepancy while minimizing the trade cost function along the trading path from the initial portfolio toward the target optimal portfolio. | 09-25-2014 |