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Michaud, MA
Corinne Michaud, Salem, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090098581 | Tyrosine phosphorylation sites - The invention discloses 482 novel phosphorylation sites identified in carcinoma and/or leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above. | 04-16-2009 |
Dennis Paul Michaud, Dracut, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110137022 | METHOD FOR THE ANALYSIS OF OLIGONUCLEOTIDES - A method for the analysis of oligonucleotides is provided. The method comprises: desalting a mixture of oligonucleotides under conditions such that there is substantially no separation of the mixture of oligonucleotides, and/or by on-line desalting, introducing the desalted mixture of oligonucleotides into a mass spectrometer; and quantifying one or more oligonucleotides comprised in the mixture by mass spectrometry. | 06-09-2011 |
Donald A. Michaud, Marblehead, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080271413 | Compresent insulation arrangement for building openings - A window frame insulation assembly and sealing arrangement, comprising an elongated, extruded block of foam material having a first or inner side and a second or outer side. A unitary air fin is co-extruded therewith. The air fin comprises an elongated flange of flexible foam material. The air fin and the elongated block define an elongated receiving-channel that is filled with a foam compression rod there between creating a seal for blocking air and moisture from a building in which said window frame assembly has been placed. | 11-06-2008 |
| 20110067349 | Compresent insulation arrangement for building openings - A window frame insulation assembly and sealing arrangement, comprising an elongated, extruded block of foam material having a first or inner side and a second or outer side. A unitary air fin is co-extruded therewith. The air fin comprises an elongated flange of flexible foam material. The air fin and the elongated block define an elongated receiving-channel that is filled with a foam compression rod there between creating a seal for blocking air and moisture from a building in which said window frame assembly has been placed. | 03-24-2011 |
Francis P Michaud, Hudson, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110092838 | QT INTERVAL MONITORING SYSTEM WITH ALARMS AND TRENDING - An ECG monitoring system continuously monitors a patient's ECG waveform and periodically identifies the patient's QT interval. QT interval values are averaged over time and a corrected interval value QTc and a change in QTc relative to a baseline, dQTc, are periodically produced. An alarm is responsive to updated QT interval values and issues an alarm whenever a selected QT value exceeds an alarm limit. The periodically produced QT interval values are stored and a trend display may be produced showing changes in the QT interval information over different periods of time. The trend display may selectively display the trend information either graphically or in tabular form. | 04-21-2011 |
Gregory Allen Michaud, Stow, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100151484 | KINASE AND UBIQUINATION ASSAYS - Compositions, including antibodies, polypeptides, and organic molecules, kits, and methods for probing molecular interactions (e.g., deubiquination, ubiquination and kinase activity), e.g., using resonance energy transfer (RET) are provided. | 06-17-2010 |
Neil Michaud, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100196388 | TARGETED BINDING AGENTS DIRECTED TO SONIC HEDGEHOG HOMOLOG AND USES THEREOF - The invention relates to targeted binding agents against human sonic hedgehog homolog (Shh) and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to Shh. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of Shh and as diagnostics. | 08-05-2010 |
Richard O. Michaud, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080288420 | Portfolio Optimization by Means of Meta-Resampled Efficient Frontiers - A computer-implemented method and computer program product for selecting a portfolio weight (subject to specified constraints) for each of a plurality of assets of an optimal portfolio. A mean-variance efficient frontier is calculated based on input data characterizing the defined expected return and the defined standard deviation of return of each of the plurality of assets. Multiple sets of optimization inputs are drawn from a distribution of simulated optimization inputs consistent with the defined expected return, the defined standard deviation of return of each of the plurality of assets and then a simulated mean-variance efficient frontier is computed for each set of optimization inputs. A meta-resampled efficient frontier is determined as a statistical mean of associated portfolios among the simulated mean-variance efficient frontiers, and a portfolio weight is selected for each asset from the meta-resampled efficient frontier according to a specified investment objective. The number of simulations and the number of simulation periods is determined on the basis of a specified level of forecast certainty. | 11-20-2008 |
Robert Michaud, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080288420 | Portfolio Optimization by Means of Meta-Resampled Efficient Frontiers - A computer-implemented method and computer program product for selecting a portfolio weight (subject to specified constraints) for each of a plurality of assets of an optimal portfolio. A mean-variance efficient frontier is calculated based on input data characterizing the defined expected return and the defined standard deviation of return of each of the plurality of assets. Multiple sets of optimization inputs are drawn from a distribution of simulated optimization inputs consistent with the defined expected return, the defined standard deviation of return of each of the plurality of assets and then a simulated mean-variance efficient frontier is computed for each set of optimization inputs. A meta-resampled efficient frontier is determined as a statistical mean of associated portfolios among the simulated mean-variance efficient frontiers, and a portfolio weight is selected for each asset from the meta-resampled efficient frontier according to a specified investment objective. The number of simulations and the number of simulation periods is determined on the basis of a specified level of forecast certainty. | 11-20-2008 |