Patent application number | Description | Published |
20090215125 | DEVICES AND PROCESSES FOR NUCLEIC ACID EXTRACTION - Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in fluid communication with the first port and the second port. The binding chamber comprises an unmodified flat glass surface effective for binding a heterogeneous population of nucleic acids. The first port, second port, and binding chamber define a continuous fluid pathway that is essentially free of nucleic acid-specific binding sites. | 08-27-2009 |
20090325220 | METHODS AND APPARATUS FOR STERILITY TESTING - Methods and apparatus for testing the sterility of a product to be administered to a patient. The sterility of the product is tested by monitoring the pH change of a culture medium in contact with any culturable organisms (e.g., bacteria) that are collected by filtration of the product to be tested. | 12-31-2009 |
20100021958 | FLUORESCENT pH DETECTOR SYSTEM AND RELATED METHODS - Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector. | 01-28-2010 |
20100047808 | DEVICE AND METHOD FOR EXTRACTION AND ANALYSIS OF NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES - Device and methods for extracting and analyzing nucleic acids from biological samples. | 02-25-2010 |
20100174058 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS - Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group. | 07-08-2010 |
20110203688 | NUCLEIC ACID EXTRACTION ON CURVED GLASS SURFACES - Processes for extracting nucleic acid from a biological sample and related assemblies and kits are disclosed. The processes comprise the steps of (a) providing a device comprising an inner surface, an outer surface, a first port, and a second port, wherein the inner surface is composed of unmodified, smooth glass and defines a tubular lumen providing fluid communication between the first port and second port, wherein the lumen is circular, oval, or elliptical in cross-section, and wherein the lumen is essentially free of nucleic acid-specific binding sites; (b) introducing a nucleic acid-containing sample into the lumen of the device via the first port; (c) allowing nucleic acid in the sample to bind to the unmodified smooth glass surface; and (d) washing the bound nucleic acid. | 08-25-2011 |
20110236988 | FLUORESCENT pH DETECTOR SYSTEM AND RELATED METHODS - Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector. | 09-29-2011 |
20120237939 | DEVICES AND PROCESSES FOR NUCLEIC ACID EXTRACTION - Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in fluid communication with the first port and the second port. The binding chamber comprises an unmodified flat glass surface effective for binding a heterogeneous population of nucleic acids. The first port, second port, and binding chamber define a continuous fluid pathway that is essentially free of nucleic acid-specific binding sites. | 09-20-2012 |
20120252017 | DEVICE AND METHOD FOR EXTRACTION AND ANALYSIS OF NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES - Device and methods for extracting and analyzing nucleic acids from biological samples. | 10-04-2012 |
20120296075 | GRAVITY FLOW FLUIDIC DEVICE FOR NUCLEIC ACID EXTRACTION - A system, method, and kit for extracting nucleic acid from a sample containing nucleic acid uses an extraction device with an elongate channel. Fluids are provided to the channel via gravity feed to the inlet port. The flow rate and other flow behavior may be controlled with a siphon provided at the outlet port. | 11-22-2012 |
20120301880 | ALKYL AMINE COMPOUNDS FOR FLUORESCENT LABELING - Alkyl amine dyes, oligonucleotide probes prepared from the alkyl amine dyes, phosphoramidites and solid supports prepared from the alkyl amine dyes, and methods of labeling biological agents using the alkyl amine dyes. | 11-29-2012 |
20120322161 | FLUORESCENT pH DETECTOR SYSTEM AND RELATED METHODS - Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector. | 12-20-2012 |
20130130402 | FLUORESCENT COMPOUNDS, COMPOSITIONS, AND METHODS FOR USING THE COMPOUNDS AND COMPOSITIONS - Low pKa fluorescent compounds, compositions that include the compounds, bioconjugates made from the compounds, and methods for making and using the compounds and bioconjugates. | 05-23-2013 |
20140186849 | FLUORESCENT DETECTOR SYSTEMS FOR THE DETECTION OF CHEMICAL PERTURBATIONS IN STERILE STORAGE DEVICES - System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags. | 07-03-2014 |