Patent application number | Description | Published |
20090131401 | Transcription factor modulating compounds and methods of use thereof - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms. | 05-21-2009 |
20090131481 | Transcription Factor Modulating Compounds and Methods of Use Thereof - Substituted benzimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of using substituted benzimidazole compounds, in, e.g., reducing virulence and infectivity, inhibiting biofilms and treating bacterial infections are also provided. | 05-21-2009 |
20090170812 | Transcription factor modulating compounds and methods of use thereof - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms. | 07-02-2009 |
20110059962 | TRANSCRIPTION FACTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of using substituted benzimidazole compounds, in, e.g., reducing virulence and infectivity, inhibiting biofilms and treating bacterial infections, are also provided. | 03-10-2011 |
20110218168 | SUBSTITUTED POLYAMINES AS INHIBITORS OF BACTERIAL EFFLUX PUMPS - Disclosed are methods of treating bacterial infections including those caused by multidrug resistant bacteria using polyamine efflux pump inhibiting compounds, including for example N-benzylated polyazaalkanes, N-benzylated polyaminoalkanes, or mixed N-benzylated poly(aza/amino)alkanes, optionally in combination with other drugs such as antibiotics, as well as pharmaceutical compositions thereof. | 09-08-2011 |
20120209003 | METHODS FOR IDENTIFYING AND USING MarR FAMILY POLYPEPTIDE BINDING COMPOUNDS - Methods for identifying MarR family inhibiting compounds are described. The methods include the use of computer aided rational based drug design programs and three dimensional structures of MarR family polypeptides. | 08-16-2012 |
20130109617 | SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF BACILLUS ANTHRACIS INFECTIONS | 05-02-2013 |
20130144038 | CRYSTAL STRUCTURE OF A MarR FAMILY POLYPEPTIDE - The crystal structure of the product, crystals of the MarR protein, a regulator of multiple antibiotic resistance in | 06-06-2013 |
20160030451 | SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF BACILLUS ANTHRACIS INFECTIONS - Methods and compositions for the treatment of | 02-04-2016 |
20160030453 | METHODS OF INCREASING ORAL BIOAVAILABILITY OF TETRACYCLINES - Methods for increasing the oral bioavailability of tetracycline compounds are described. | 02-04-2016 |
Patent application number | Description | Published |
20100227850 | METHODS FOR PREVENTING AND TREATING MICROBIAL INFECTIONS BY MODULATING TRANSCRIPTION FACTORS - The current invention is based, inter alia, on the finding that the transcription factor MarA, and homologues of MarA, e.g., Rob and SoxS, are virulence factors. Accordingly, the invention discloses methods for screening compounds for their ability to modulate these virulence factors. The invention further describes methods for treating and preventing bacterial infections by modulating the expression and/or activity of transcription factors. In addition, the invention provides a method for identifying other virulence factors. | 09-09-2010 |
20100298540 | Crystal Structure of a MarR Family Polypeptide - The crystal structure of the product, crystals of the MarR protein, a regulator of multiple antibiotic resistance in | 11-25-2010 |
20110015375 | Methods for Identifying and Using MarR Family Polypeptide Binding Compounds - Methods for identifying MarR family inhibiting compounds are described. The methods include the use of computer aided rational based drug design programs and three dimensional structures of MarR family polypeptides. | 01-20-2011 |
20110230523 | TRANSCRIPTION FACTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms. | 09-22-2011 |
20110306611 | Transcription factor modulating compounds and methods of use thereof - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms. | 12-15-2011 |
Patent application number | Description | Published |
20110291846 | EFFICIENT AND SAFE DOOR LOCKING CONTROL IN POWER-OFF AND POWER-ON CONDITIONS - Systems, methods, and devices that efficiently control the operating state of an electromagnetic lock under power on and power off conditions are presented. A lock component includes a solenoid component (e.g., bi-stable latching solenoid) that holds a lock pin in a locked or unlocked position without using power to hold the lock pin in the desired position, and using power to transition from one position to another position. A sensor component senses when power to the lock component will be lost, and if the lock pin is not in the desired position for the power off condition, the lock pin can be transitioned to the desired position, and if the lock pin is in the desired position for power off condition, the lock component can maintain the lock pin in the desired position, while the lock component is in the power off condition. | 12-01-2011 |
20110291848 | VARIABLE ADJUSTABLE DOOR LATCH - Systems, methods, and devices that efficiently stop and latch a door are presented. A first bracket component is attached to a door frame and has an overhang portion, comprising a holder component, that extends into the doorway to act as a door stop. A second bracket component, comprising an extended portion, is desirably adjusted in position in relation to the holder component and attached to the door such that the extended portion has a desired amount of overlap on the holder component, wherein the amount of overlap corresponds to an amount of latching force in accordance with the force profile associated with the extended portion based at least in part on shape of the extended portion. An operation device is attached to the first bracket component and/or second bracket component and the door latching holds the door in the desired position to facilitate operations of the operation component. | 12-01-2011 |
20120119523 | SELF-ALIGNING SAFETY LOCK - A safety lock mechanism is provided that facilitates accurate and consistent alignment between a locking bolt and a locking receptacle prior to engaging the locking bolt. To this end, a safety lock configured to mount to a door frame is provided with an internally disposed hard stop that protects the electrical and mechanical components within the safety lock housing from door impact shock. An extended portion of the hard stop protrudes through the housing facing the direction of door travel. A corresponding receptacle assembly configured to mount to the door is fabricated to include a bolt receptacle hole as well as an open window that engages with the extended portion of the hard stop when the door is in the closed position. When the window in the receptacle is engaged with the extended portion of the hard stop, door movement is limited in five directions even when the locking bolt is not yet engaged. An optional magnet embedded in the hard stop can limit door movement in the sixth direction by magnetically latching to a striking plate mounted behind the window. Thus, the window and the hard stop pre-position the receptacle for proper alignment between the locking bolt and the locking bolt receptacle, ensuring that the locking bolt will properly engage with the receptacle when advanced. | 05-17-2012 |
Patent application number | Description | Published |
20110099351 | Use of Similarity Hash to Route Data for Improved Deduplication in a Storage Server Cluster - A technique for routing data for improved deduplication in a storage server cluster includes computing, for each node in the cluster, a value collectively representative of the data stored on the node, such as a “geometric center” of the node. New or modified data is routed to the node which has stored data identical or most similar to the new or modified data, as determined based on those values. Each node stores a plurality of chunks of data, where each chunk includes multiple deduplication segments. A content hash is computed for each deduplication segment in each node, and a similarity hash is computed for each chunk from the content hashes of all segments in the chunk. A geometric center of a node is computed from the similarity hashes of the chunks stored in the node. | 04-28-2011 |
20110191522 | Managing Metadata and Page Replacement in a Persistent Cache in Flash Memory - A persistent cache is implemented in a flash memory that includes a journal section that stores metadata and a low frequency section and a high frequency section that store data entries. Writing new metadata to the persistent cache includes sequentially advancing to a next sector containing an invalid metadata entry, saving a working copy of the sector in RAM, writing metadata corresponding to one or more new data entries in the working copy, and overwriting the sector in the flash memory containing the invalid entry with the working copy. Writes to the low frequency and high frequency sections occur sequentially in the current locations of a low frequency section pointer and a high frequency section pointer, respectively. In a persistent cache, the reconstruction of a non-persistent cache utilizes the metadata entry that has the most recent timestamp. | 08-04-2011 |
20130018854 | USE OF SIMILARITY HASH TO ROUTE DATA FOR IMPROVED DEDUPLICATION IN A STORAGE SERVER CLUSTER - A technique for routing data for improved deduplication in a storage server cluster includes computing, for each node in the cluster, a value collectively representative of the data stored on the node, such as a “geometric center” of the node. New or modified data is routed to the node which has stored data identical or most similar to the new or modified data, as determined based on those values. Each node stores a plurality of chunks of data, where each chunk includes multiple deduplication segments. A content hash is computed for each deduplication segment in each node, and a similarity hash is computed for each chunk from the content hashes of all segments in the chunk. A geometric center of a node is computed from the similarity hashes of the chunks stored in the node. | 01-17-2013 |
20130332558 | USING LOGICAL BLOCK ADDRESSES WITH GENERATION NUMBERS AS DATA FINGERPRINTS FOR NETWORK DEDUPLICATION - The technique introduced here involves using a block address and a corresponding generation number as a “fingerprint” to uniquely identify a sequence of data within a given storage domain. Each block address has an associated generation number which indicates the number of times that data at that block address has been modified. This technique can be employed, for example, to determine whether a given storage server already has the data, and to avoid sending the data to that storage server over a network if it already has the data. It can also be employed to maintain cache coherency among multiple storage nodes. | 12-12-2013 |
20150248240 | USING LOGICAL BLOCK ADDRESSES WITH GENERATION NUMBERS AS DATA FINGERPRINTS FOR NETWORK DEDUPLICATION - The technique introduced here involves using a block address and a corresponding generation number as a “fingerprint” to uniquely identify a sequence of data within a given storage domain. Each block address has an associated generation number which indicates the number of times that data at that block address has been modified. This technique can be employed, for example, to determine whether a given storage server already has the data, and to avoid sending the data to that storage server over a network if it already has the data. It can also be employed to maintain cache coherency among multiple storage nodes. | 09-03-2015 |
Patent application number | Description | Published |
20130275396 | Systems and Methods for Selecting Data Compression for Storage Data in a Storage System - Storage systems and methods to improve space saving from data compression by providing a plurality of compression processes, and optionally, one or more parameters for controlling operation of the compression processes and selecting from the plurality of compression processes and the parameters to satisfy resource limits, such as CPU usage and memory usage. In one embodiment, the methods takes into account the content-type, such as text file or video file, and select the compression process and parameters that provide the greatest space savings for that content type while also remaining within a defined resource-usage limit. | 10-17-2013 |
20140136789 | HOST SIDE DEDUPLICATION - One or more techniques and/or systems are provided for performing host side deduplication. Host side deduplication may be performed upon writeable data within a write request received at a host computing device configured to access data stored by a storage server. The host side deduplication may be performed at the host computing device to determine whether the writeable data is already stored by the storage server based upon querying a host side cache comprising data stored by a storage server and/or a data structure comprising unique signatures of data stored by the storage server. If the writeable data is stored by the storage server, then a deduplication notification excluding the writeable data may be sent to the storage server, otherwise a write command comprising the writeable data may be sent. Accordingly, unnecessary network traffic of redundant data already stored by the storage server may be reduced. | 05-15-2014 |
20140173220 | Using Logical Block Addresses with Generation Numbers as Data Fingerprints to Provide Cache Coherency - The technique introduced here involves using a block address and a corresponding generation number as a “fingerprint” to uniquely identify a sequence of data within a given storage domain. Each block address has an associated generation number which indicates the number of times that data at that block address has been modified. This technique can be employed, for example, to maintain cache coherency among multiple storage nodes. It can also be employed to avoid sending the data to a network node over a network if it already has the data. | 06-19-2014 |
Patent application number | Description | Published |
20080220441 | Advanced drug development and manufacturing - X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical, for estimating the binding selectivity of a chemical versus chemical analogs, for measuring post-translational modifications of proteins, and for drug manufacturing. | 09-11-2008 |
20090087919 | Method and Apparatus for Measuring Protein Post-Translational Modification - The present invention includes a method for analyzing reactions. The method includes the steps of providing a solution of at least one acceptor chemical and at least one donor chemical. The donor chemical is capable of donating a chemical moiety to the acceptor chemical. The solution further includes at least one controller chemical that affects the reaction between the donor chemical and the acceptor chemical. The solution is then incubated so that a portion of the acceptor chemical reacts with the donor chemical to form an acceptor product. Unreacted donor chemical is separated from the acceptor product. The acceptor product or the donor chemical is then measured using X-ray fluorescence. Another aspect of the present invention includes a method for analyzing protein function. The method includes the steps of providing a solution of at least one acceptor chemical and at least one donor chemical. The donor chemical is capable of donating a chemical moiety to the acceptor chemical. The donor chemical includes a functional group selected from ester, anhydride, imide, acyl halide, and amide. The solution is then incubated so that a portion of the acceptor chemical reacts with the donor chemical to form an acceptor product. Unreacted donor chemical is separated from the acceptor product. The acceptor product or the donor chemical is then measured using X-ray fluorescence. Yet another aspect of the present invention includes a method for analyzing protein function. The method includes the steps of providing a solution of at least one acceptor chemical and at least one donor chemical. The solution is then incubated so that a portion of the acceptor chemical reacts with the donor chemical to form an acceptor product. Unreacted donor chemical is separated from the acceptor product. The acceptor product or the donor chemical is then measured using X-ray fluorescence. An additional analytical method is also used to measure either the acceptor product or the donor chemical. | 04-02-2009 |
20150309021 | Advanced Drug Development and Manufacturing - X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing. | 10-29-2015 |
Patent application number | Description | Published |
20100147240 | METHOD OF STARTING SPARK-IGNITION DIRECT INJECTION (SIDI) ENGINES - A cold start control module for a direct injection engine includes a fuel flow determination module and a cylinder activation/deactivation module. The fuel flow determination module determines a requested fuel flow. The cylinder activation/deactivation module deactivates at least one of cylinders when the requested fuel flow exceeds a maximum fuel flow of the fuel pump during cold start. | 06-17-2010 |
20100280742 | CONTROL SYSTEM AND METHOD FOR CONTROLLING AN ENGINE IN RESPONSE TO DETECTING AN OUT OF RANGE PRESSURE SIGNAL - A method and control module for operating an engine that includes a pressure range determination module that determines a pressure value for a pressure sensor in a fuel rail is out of range. A fuel rail pressure estimate module that determines a predicted pressure value. An engine control module that operates the engine using the predicted pressure value. | 11-04-2010 |
20100288231 | CONTROL SYSTEMS AND METHODS FOR NEWLY ASSEMBLED ENGINES - An engine control system for a vehicle comprises a combustion control module and an engine startup module. The combustion control module selectively controls a spark timing and airflow into an engine based on a counter value. The engine startup module, when the counter value is one of greater than and less than a predetermined final value, controls an equivalence ratio (EQR) of an air/fuel mixture provided to the engine during an engine cranking period based on a fuel rail pressure and controls the EQR during an engine running period based on the fuel rail pressure and an engine runtime period. The counter value is set to the predetermined final value after the engine is started for a first time after the engine is assembled. | 11-18-2010 |
20110288746 | CONTROL SYSTEM AND METHOD FOR IMPROVING COLD STARTABILITY OF SPARK IGNITION DIRECT INJECTION (SIDI) ENGINES - A control system includes an engine enable module and a fuel control module. The engine enable module determines whether predetermined operating conditions of a spark ignition direct injection (SIDI) engine are satisfied and enables an engine prime mode when the predetermined operating conditions are satisfied. The fuel control module controls a fuel injector to deliver a prime pulse to a cylinder of the SIDI engine when the engine prime mode is enabled. The fuel injector delivers the prime pulse by opening for a pulse width to inject fuel directly into the cylinder when the SIDI engine is stopped. | 11-24-2011 |
20120024252 | SYSTEM AND METHOD FOR STARTING AN ENGINE USING LOW ELECTRIC POWER - A method and a system are provided for starting an engine that is employed for propulsion of a vehicle. The method includes determining that an engine start via a starter is desired, wherein the starter is powered by an energy storage device. The method also includes determining a state of charge of the energy storage device. The method additionally includes commanding the starter to crank the engine at a first predetermined speed, if the energy storage device is at or above a predetermined state of charge and supplying fuel to the engine for a first predetermined number of fueling events. Furthermore, the method includes commanding the starter to crank the engine at a second predetermined speed that is lower than the first predetermined speed and supplying fuel to the engine for a second predetermined number of fueling events, if the energy storage device is below the predetermined state of charge. | 02-02-2012 |
Patent application number | Description | Published |
20090220979 | Methods and Apparatus for Magnetic Separation of Cells - Described here is an automated robotic device that isolates circulating tumor cells (CTCs) or other biological structures with extremely high purity. The device uses powerful magnetic rods covered in removable plastic sleeves. These rods sweep through blood samples, capturing, e.g., cancer cells labeled with antibodies linked to magnetically responsive particles such as superparamagnetic beads. Upon completion of the capturing protocol, the magnetic rods undergo several rounds of washing, thereby removing all contaminating blood cells. The captured target cells are released into a final capture solution by removing the magnetic rods from the sleeves. Additionally, cells captured by this device show no reduced viability when cultured after capture. Cells are captured in a state suitable for genetic analysis. Also disclosed are methods for single cell analysis. Being robotic allows the device to be operated with high throughput. | 09-03-2009 |
20110312518 | MICROFLUIDIC DEVICES FOR MEASUREMENT OR DETECTION INVOLVING CELLS OR BIOMOLECULES - Embodiments of the invention are related to microfluidic devices for detecting or determining the concentration of biomolecules in an analyte comprising: a channel, wherein a surface of said channel is fabricated to be functionalized with at least one molecule selected to interact with a biomolecule, said channel being configured to interact with a microsphere, wherein a surface of said microsphere is fabricated to be functionalized with at least one same or different molecule selected to interact with said biomolecule; a second channel in fluid communication with said first channel; a system to move fluid containing said microsphere through said first and second channels; and a system to measure a change in electrical impedance or optical microscopy across said second channel as said microsphere moves through said second channel. Other embodiments concern related devices, and methods of making and using. | 12-22-2011 |
20120045828 | Apparatus for Magnetic Separation of Cells - Described here is an automated robotic device that isolates circulating tumor cells (CTCs) or other biological structures with extremely high purity. The device uses powerful magnetic rods covered in removable plastic sleeves. These rods sweep through blood samples, capturing, e.g., cancer cells labeled with antibodies linked to magnetically responsive particles such as superparamagnetic beads. Upon completion of the capturing protocol, the magnetic rods undergo several rounds of washing, thereby removing all contaminating blood cells. The captured target cells are released into a final capture solution by removing the magnetic rods from the sleeves. Additionally, cells captured by this device show no reduced viability when cultured after capture. Cells are captured in a state suitable for genetic analysis. Also disclosed are methods for single cell analysis. Being robotic allows the device to be operated with high throughput. | 02-23-2012 |
20140102901 | NEGATIVE DIELECTROPHORESIS FOR SELECTIVE ELUTION OF IMMUMO-BOUND PARTICLES - The procedure of dielectric electrophoresis (dielectrophoresis or DEP) utilizes field-polarized particles that move under the application of positive (attractive) and/or negative (repulsive) applied forces. This invention uses negative dielectric electrophoresis (negative dielectrophoresis or nDEP) within a microchannel separation apparatus to make particles move (detached) or remain stationary (attached). In an embodiment of the present invention, the nDEP force generated was strong enough to detach Ag-Ab (antigen-antibody) bonds, which are in the order of 400 pN (piconewtons) while maintaining the integrity of the system components. | 04-17-2014 |
Patent application number | Description | Published |
20080234192 | COMPOSITIONS AND METHODS OF USE FOR TREATING CARDIOVASCULAR DISEASE - In one aspect, the present invention provides isolated oxidation resistant mutant apoA-I polypeptides comprising an amino acid sequence substantially homologous to SEQ ID NO:4, the mutant apoA-I polypeptide comprising a combination of: (1) a conservative amino acid substitution at residue Tyr192; and (2) at least one conservative amino acid substitution at residue Met86, Met112, or Met148, wherein the mutant apoA-I polypeptide is resistant to modification by an oxidizing agent. In another aspect, the invention provides a method of promoting cholesterol efflux activity in a mammalian subject in need thereof, the method comprising the step of administering an effective amount of an oxidation resistant apoA-I agonist to the subject to promote cholesterol efflux. | 09-25-2008 |
20100311595 | LIPOPHILIC DRUG DELIVERY VEHICLE AND METHODS OF USE THEREOF - The invention provides compositions and methods for delivery of a bioactive agent to an individual. Delivery vehicles are provided that include a bioactive agent in disc shaped particles that include one or more lipid binding polypeptides circumscribing the perimeter of a lipid bilayer in which the bioactive agent is localized. Chimeric lipid binding polypeptides are also provided and may be used to add additional functional properties to the delivery particles. | 12-09-2010 |
20120309628 | BIOACTIVE AGENT DELIVERY PARTICLES - The invention provides compositions and methods for delivery of a bioactive agent to an individual. Delivery vehicles are provided that include a bioactive agent in disc shaped particles that include one or more lipid binding polypeptides circumscribing the perimeter of a lipid bilayer in which the bioactive agent is localized. Chimeric lipid binding polypeptides are also provided and may be used to add additional functional properties to the delivery particles. | 12-06-2012 |
20140162376 | COMPOSITIONS AND METHODS TO ASSESS THE CAPACITY OF HDL TO SUPPORT REVERSE CHOLESTEROL TRANSPORT - The invention provides compositions and methods for assessing the capacity of high density lipoprotein (HDL) to support reverse cholesterol transport in blood by measuring exchange if HDL-specific spin-labeled lipoprotein probes and electron paramagnetic spectroscopy. The invention also provides methods to identify individuals at risk for cardiovascular disease, to monitor the treatment of cardiovascular disease and in the development of therapies to treat cardiovascular disease. The invention also provides methods to identify individuals at risk for Alzheimer's disease, to monitor the treatment of Alzheimer's disease and in the development of therapies to treat Alzheimer's disease. | 06-12-2014 |
20140308339 | LIPOPHILIC DRUG DELIVERY VEHICLE AND METHODS OF USE THEREOF - The invention provides compositions and methods for delivery of a bioactive agent to an individual. Delivery vehicles are provided that include a bioactive agent in disc shaped particles that include one or more lipid binding polypeptides circumscribing the perimeter of a lipid bilayer in which the bioactive agent is localized. Chimeric lipid binding polypeptides are also provided and may be used to add additional functional properties to the delivery particles. | 10-16-2014 |
Patent application number | Description | Published |
20090085347 | FLANGE-FORMING SYSTEM FOR TUBE AND RELATED METHODS - A system is configured for forming a flange at an end of a tube. The system includes a collar configured to receive the tube. A first roller engages the collar and a second roller is configured to cooperate with the first roller to rotate the collar and the tube. A rotatable cam is disposed about the second roller and includes a cam surface configured to bend the end of the tube to thereby form the flange. The collar may be configured to restrict axial movement of the tube relative to the collar. Additionally or alternatively, the collar may be configured to restrict rotational movement of the tube relative to the collar. | 04-02-2009 |
20090085349 | DUCT SYSTEMS AND RELATED METHODS - A juncture assembly between first and second tubes includes first and second flanges formed at the ends of the tubes. The flanges include respective legs in a confronting relationship and defining a gap between them. A gasket member contacts the flanges and is configured to prevent travel of fluids through the gap. The gasket member may, for example, be disposed in the gap between the first and second legs. | 04-02-2009 |
20100038902 | Tube Coupling and Related Methods - A juncture assembly is provided between first and second ends of respective first and second tubes. The assembly includes a first flange that is located at the first end and a second flange that is located at the second end, with the second flange being in confronting relationship with the first flange. The first and second flanges define a gap between them. A gasket member contacts the first and second flanges and is configured to prevent flow of fluids through the gap. A clamp member of the assembly secures the gasket member to the first and second flanges with the clamp member including a channel for receiving the first and second flanges and first and second restriction elements that extend into the channel for positioning the first and second flanges within the channel. | 02-18-2010 |
20110296888 | FLANGE-FORMING SYSTEM FOR TUBE AND RELATED METHODS - A system is configured for forming a flange at an end of a tube. The system includes a collar configured to receive the tube. A first roller engages the collar and a second roller is configured to cooperate with the first roller to rotate the collar and the tube. A rotatable cam is disposed about the second roller and includes a cam surface configured to bend the end of the tube to thereby form the flange. The collar may be configured to restrict axial movement of the tube relative to the collar. Additionally or alternatively, the collar may be configured to restrict rotational movement of the tube relative to the collar. | 12-08-2011 |
20110296894 | FLANGE-FORMING SYSTEM FOR TUBE AND RELATED METHODS - A system is configured for forming a flange at an end of a tube. The system includes a collar configured to receive the tube. A first roller engages the collar and a second roller is configured to cooperate with the first roller to rotate the collar and the tube. A rotatable cam is disposed about the second roller and includes a cam surface configured to bend the end of the tube to thereby form the flange. The collar may be configured to restrict axial movement of the tube relative to the collar. Additionally or alternatively, the collar may be configured to restrict rotational movement of the tube relative to the collar. | 12-08-2011 |
20130324028 | DAMPER ACCESS ASSEMBLY - A damper access assembly includes an adapter and a removable damper access duct section for use in a ventilation duct system to access a damper. The adapter includes a radially outwardly directed flange. Each of the ends of the damper access duct section includes a radially outwardly directed flange. The flange of the adapter is configured to be operatively and releasably coupled to one of the flanges of the damper access duct section. The other second flange at the other end of the damper access duct section is configured to be operatively and releasably coupled to the ductwork. A technician may release the damper access duct section from the adapter and from the ductwork and remove the damper access duct section to access the damper. The damper access assembly may include one or more clamps that cooperate with the flanges of the adapter and the removable access duct section. | 12-05-2013 |
20130324029 | DAMPER ACCESS ASSEMBLY, CLAMP ASSEMBLY, AND CLAMP MEMBER - A clamp assembly is provided for use in a duct system. The clamp assembly includes a clamp member including a base portion and first and second lateral portions. The first and second lateral portions extend less than the full circumferential length of the base portion. The clamp assembly may include a first member, a second member, and a hinge operatively coupling the first member to the second member. A damper access assembly includes an adapter, a damper access duct section, and an annular clamp member. A first flange of the adapter and a second flange of the duct section are configured to form a generally T-shaped joint between the adapter and the damper access duct section. The clamp member is configured to removably secure the adapter to the damper access duct section. The damper access duct section is configured to be removable relative to the damper enclosure and the ductwork. | 12-05-2013 |
20130331022 | FLUID CONDITIONING DEVICES AND ASSEMBLIES - A fluid conditioning assembly includes a fluid conditioning device defining a passage and having a first end and a second end. A control element is supported within the passage. At least the first end includes an integral radially outwardly directed flange. The integral radially outwardly directed flange is configured to be operatively and releasably coupled to a first radially outwardly directed flange of a first duct section. A technician may release the fluid conditioning device from the first duct section to remove the fluid conditioning device from the ventilation duct system for accessing the control element of the fluid conditioning device. | 12-12-2013 |
Patent application number | Description | Published |
20110202865 | PERSPECTIVE VIEW - A method is provided for displaying a graphical user interface to a user. The graphical user interface includes a perspective, which is an arrangement of areas, each area containing at least one portlet which presents one aspect of stored information. The graphical user interface allows a user to easily switch between different perspectives, each perspective presenting a different layout of areas. Within each area, different portlets can be made visible using tabs to switch between the portlets. A new portlet can also be created within an area, as long as that type of portlet is allowed in that particular area. The invention allows a user to easily manage the view of many pieces of information without the clutter usually associated with many windows. | 08-18-2011 |
20110202873 | MENU LAUCHING STRUCTURE - A method is provided for acting on a selected menu item. The menu items are defined so as to have associated with them a label, a launch type, and a parameter. Depending on the launch type of a selected menu item, different actions are taken and the parameter is used in different ways. If the launch type indicates that a list or a form is to be presented upon selection of a menu item, then the parameter is passed as an input to a list or form subsystem. If the launch type indicates that an action specific to the selected menu item is to be performed, then a pre-defined function within an object representing the entity indicated by the selected menu item is called, the name of the pre-defined function being determined from the value of the parameter. The method of defining and acting on menu items allows both common functions and functions specific to a menu item to be associated with menu items. | 08-18-2011 |
20120005607 | FLOATING WINDOW - A method is provided for creating a floating window in a perspective view of data, such as network management data. The floating window can be moved freely about the perspective and resized, thereby allowing other data of importance which is tied to areas of the perspective to be seen. Portlets, containing aspects of data, can be located in the floating window. The floating window in modal mode is particularly useful for requiring a user to interact with or view data without being able to interact with data in the rest of the perspective. The floating window can also be created in non-modal mode, which allows a user to move portlets from existing areas to the more flexible floating window. | 01-05-2012 |
20120005618 | SUBFORMS - A method is provided for displaying subforms in a perspective having areas and portlets. An entity represented by a portlet is configured using a form within the portlet. Sub-entities may require configuration as part of configuring the first entity. When a user configures a sub-entity, a subform is opened presenting means of configuring the sub-entity. The subform overlays most of the parent form, making the parent form inaccessible until configuration of the sub-entity is either accepted or cancelled. Using subforms, it is apparent to a user that configuration of the first entity is not complete until all related sub-entities have also been configured. Use of subforms within a portlet also allows other information necessary for configuration of the entity or sub-entities to be viewed by the user. | 01-05-2012 |
20120005620 | INTELLIGENT AUTO-CREATION OF NEW PORTLETS - A method is provided for keeping presentation of information to a minimum. A perspective comprises areas, and each area can have one or more portlets which display information. Each area has an associated list of portlet types that can be instantiated within the area. Each portlet can be manually placed into or out of a locked state. Various portlets can also be in a dirty state if they contain unsaved information, such as in a partially completed form. When a new portlet is to be added to the perspective, first an area which supports creation of that type of portlet is selected. The existing portlets within that area are then examined, and if one exists which is not locked and is not dirty, then it is replaced with the new portlet. If no such existing portlet is eligible for replacement, then the new portlet is created and added to the existing portlets. In this way, portlets in which a user is no longer interested may be replaced with newer portlets of more immediate interest, thereby reducing clutter within the perspective view of the information. | 01-05-2012 |
20120005629 | TIGHTLY COUPLED LISTS AND FORMS FOR CREATING/VIEWING/EDITING DATA - A graphic user interface is provided for displaying list portlets and form portlets within a perspective, the portlets representing data including entities represented in a database. The portlets have various widgets. Portlets are associated with other portlets, such that selection of a widget or of a name in one portlet may open another portlet. In this way, nested portlets can be easily navigated and entities can be configured easily. | 01-05-2012 |