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Michael J. Grogan, Winchester US

Michael J. Grogan, Winchester, MA US

Patent application numberDescriptionPublished
20080287420CYCLOPAMINE LACTAM ANALOGS AND METHODS OF USE THEREOF - The present invention relates to steroidal alkaloids useful in the treatment of hedgehog pathway related disorders, particularly cancer.11-20-2008
20080293754CYCLOPAMINE ANALOGS - The invention provides novel derivatives of cyclopamine having the following formula:11-27-2008
20080293755HETEROCYCLIC CYCLOPAMINE ANALOGS AND METHODS OF USE THEREOF - The present invention relates to steroidal alkaloids that can be used in the treatment of hedgehog pathway related disorders, particularly cancer.11-27-2008
20090012109CYCLOPAMINE ANALOGS - The invention provides novel derivatives of cyclopamine having the following formula:01-08-2009
20090099131INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III).04-16-2009
20090216022CYCLOPAMINE ANALOGS - The invention provides novel derivatives of cyclopamine having the following formula:08-27-2009
20100144775Heterocyclic Cyclopamine Analogs and Methods of Use Thereof - The present invention relates to steroidal alkaloids that can be used in the treatment of hedgehog pathway related disorders, particularly cancer.06-10-2010
20100190791Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners - The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer.07-29-2010
20100286180METHODS OF USE OF CYCLOPAMINE ANALOGS - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:11-11-2010
20110028478ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides isoxazoline FAAH inhibitors of the formula (I):02-03-2011
20110028482ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides isoxazoline FAAH inhibitors of the formula (I):02-03-2011
20110034437ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides isoxazoline FAAH inhibitors of the formula (I):02-10-2011

Patent applications by Michael J. Grogan, Winchester, MA US