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Francoise Mechin, Charenton Le Pont FR
| Patent application number | Description | Published |
|---|---|---|
| 20090275701 | Curable Composition Based On Polyurethane And On Block Copolymers, And Transparent Material Obtained From Said Composition - Curable composition comprising: (a) one or more particular polyisocyanates or a polyurethane prepolymer obtained by the polycondensation of a polyisocyanate in excess, chosen from said polyisocyanates, with one or more polyols comprising at least two free alcohol functional groups, chosen from polypropoxylated or polyethoxylated bisphenol A compounds and polyfunctional polycaprolactone-alcohols; (b) one or more polyols comprising at least two free alcohol functional groups, chosen from polypropoxylated or polyethoxylated bisphenol A compounds and polyfunctional polycaprolactone-alcohols, and polyurethane prepolymers obtained by the polycondensation of one or more polyols in excess, chosen from the above polyols, with one or more particular polyisocyanates, the ratio of the number of isocyanate functional groups of the polyisocyanate component (a) to the number of alcohol functional groups of the polyol component (b) being between 1.00 and 1.20; and (c) 5% to 80% by weight, relative to the total weight of (a), (b) and (c), of one or more polystyrene-block-polybutadiene-block-poly(methyl methacrylate) block copolymers; | 11-05-2009 |
Francoise Mechin, Lyon FR
| Patent application number | Description | Published |
|---|---|---|
| 20090143545 | Thermosetting Poly(thio)urethane Formulation Comprising at Least One Block Copolymer and Use Thereof in Optics for the Production of Organic Lenses Having Improved Toughness - The invention relates to a polymerisable liquid mixture comprising: (a) a polymerisable thermosetting composition which is a precursor by polymerisation of a first thermoset polymer material, said composition containing at least one polythiol and/or one polyol, preferably a polythiol, and at least one polyiso(thio)cyanate; and (b) a second polymer material solubilised in the aforementioned polymerisable thermosetting composition, whereby the second material (i) contains at least one block copolymer comprising at least two polymer blocks A and B, namely an elastomer block A and a hydrophilic block B, and, following polymerisation of the polymerisable mixture, (ii) forms domains which are rich in elastomer block A and which are dispersed throughout the first material, said domains being smaller than 80 nanometers and preferably smaller than 50 nanometers. The invention also relates to a transparent article having improved toughness, which is produced by means of polymerisation of the above-mentioned polymerisable mixture, comprising an alloy of a first thermoset polymer material forming the matrix of said article and of a second polymer material which is dispersed throughout said first material. The aforementioned articles have improved resistance to impact and to crack propagation. The invention is suitable for use in ophthalmic optics. | 06-04-2009 |
Ingrid Mechin, Bridgewater, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100286429 | CRYSTALLOGRAPHIC MODEL OF THE BINDING SITE AND A MODULATOR REGULATING THE CATALYTIC ACTIVITY OF PHOSPHOFRUCTOKINASE (PFK), A METHOD OF DESIGNING, SELECTING AND PRODUCING THE PFK MODULATOR, A COMPUTER-BASED METHOD FOR THE ANALYSIS OF THE INTERACTIONS BETWEEN THE MODULATOR AND PFK - The subject matters of the invention are: a crystallographic model of the binding site and a modulator regulating the catalytic activity of phosphofructokinase (PFK), a method of designing, selecting and producing a PFK modulator, a computer-based method for the analysis of the interaction between the modulator and PFK and for the analysis of molecular structures, a computer-based method of drug design, a method of assessing the ability of the potential modulator to interact in the binding site on the PFK surface, a method of providing data for generating structures and/or performing design for drugs that bind PFK, PFK homologues or analogues, complexes of PFK with a potential modulator, or complexes of PFK homologues or analogues with potential modulators, a computer system. | 11-11-2010 |
| 20110060574 | COMPUTER-BASED MODELING AND DESIGNING OF PHOSPHOFRUCTOKINASE 1 (PFK) MODULATORS - The subject matters of the invention are: a crystallographic model of the binding site and a modulator regulating the catalytic activity of phosphofructokinase (PFK), a method of designing, selecting and producing a PFK modulator, a computer based method for the analysis of the interaction between the modulator and PFK, a computer-based method the analysis of molecular structures, a method of assessing the ability of the potential modulator to interact in the binding site on the PFK surface, a method of providing data for generating structures and/or performing design for ligands binding PFK, PFK homologues or analogues, complexes of PFK with a potential modulator, or complexes of PFK homologues or analogues with potential modulators, a computer system. The invention makes it possible to design a suitable activator, which could be used to modulate PFK activity, taking advantage of PFKs capability to bind in its effector site phosphate groups or other groups with a similar potential to interact, which correspond with the substituents in positions 1, 2 and 6 of the fructose ring, or groups corresponding with positions of the fructose ring groups interacting in the PFK effector site. | 03-10-2011 |
Olivier Mechin, Vyans Le Val FR
| Patent application number | Description | Published |
|---|---|---|
| 20100280695 | BRAKING METHOD FOR HYBRID VEHICLES COMPENSATING FOR AN ELECTRIC BRAKING TORQUE - The invention relates to a braking method for a hybrid vehicle ( | 11-04-2010 |
Olivier Mechin, Hericourt FR
| Patent application number | Description | Published |
|---|---|---|
| 20100106386 | METHOD FOR BRAKING A HYBRID VEHICLE AND METHOD FOR IMPROVING A HYBRID VEHICLE IMPLEMENTING SAID METHOD - The invention relates to a method for braking a hybrid vehicle ( | 04-29-2010 |